| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Naproxen perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Naproxen_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AHNAK | AHNAK nucleoprotein | 0.1821 |
| GPC6 | glypican 6 | 0.154563 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.146579 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.144611 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.139342 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.135117 |
| EGFR | epidermal growth factor receptor | 0.114449 |
| UBC | ubiquitin C | 0.108941 |
| DSTN | destrin (actin depolymerizing factor) | 0.105886 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.103289 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0980294 |
| FN1 | fibronectin 1 | 0.0870427 |
| SRPK2 | SRSF protein kinase 2 | 0.0812455 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0811463 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.079335 |
| CERS6 | ceramide synthase 6 | 0.0776888 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0729161 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0721938 |
| LDHA | lactate dehydrogenase A | 0.0697149 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0681054 |
| JMJD1C | jumonji domain containing 1C | 0.0679829 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0668363 |
| TMSB10 | thymosin beta 10 | 0.0645681 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0637691 |
| ASPH | aspartate beta-hydroxylase | 0.0632237 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0628929 |
| PGK1 | phosphoglycerate kinase 1 | 0.0621844 |
| RPLP1 | ribosomal protein, large, P1 | 0.0609595 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0599676 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0579159 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0566794 |
| BBX | bobby sox homolog (Drosophila) | 0.0562813 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.055645 |
| SETD5 | SET domain containing 5 | 0.0555043 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0554081 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0549322 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0547056 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.052638 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0521496 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0518689 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0508582 |
| PARD3 | par-3 family cell polarity regulator | 0.0505081 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.050473 |
| SMAD3 | SMAD family member 3 | 0.0501172 |
| RPS27A | ribosomal protein S27a | 0.0495609 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0488578 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0483357 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0465751 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0461948 |
| PDE10A | phosphodiesterase 10A | 0.0460991 |
| ANXA2 | annexin A2 | 0.0451138 |
| GPHN | gephyrin | 0.044229 |
| PCBP2 | poly(rC) binding protein 2 | 0.0420933 |
| YTHDC1 | YTH domain containing 1 | 0.0419473 |
| PTMA | prothymosin, alpha | 0.0413547 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0410704 |
| RPL5 | ribosomal protein L5 | 0.039639 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0387621 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0382681 |
| RPL23 | ribosomal protein L23 | 0.037681 |
| WDR43 | WD repeat domain 43 | 0.0354896 |
| ITGA6 | integrin, alpha 6 | 0.0351023 |
| CANX | calnexin | 0.0348519 |
| YBX1 | Y box binding protein 1 | 0.0331263 |
| RACK1 | receptor for activated C kinase 1 | 0.0324662 |
| DST | dystonin | 0.0315681 |
| LSAMP | limbic system-associated membrane protein | 0.0304546 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.029684 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0291562 |
| GNAS | GNAS complex locus | 0.0284458 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0278805 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0277827 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0265944 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0262366 |
| RPL28 | ribosomal protein L28 | 0.0261253 |
| FLNB | filamin B, beta | 0.0257103 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0227218 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0224367 |
| APP | amyloid beta (A4) precursor protein | 0.0214323 |
| ACTG1 | actin gamma 1 | 0.0207814 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0193962 |
| PTK2 | protein tyrosine kinase 2 | 0.0191512 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0188143 |
| RUNX1 | runt-related transcription factor 1 | 0.0180079 |
| OSMR | oncostatin M receptor | 0.0160755 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0155788 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0151416 |
| TCF12 | transcription factor 12 | 0.0147426 |
| S100A10 | S100 calcium binding protein A10 | 0.0131221 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0117933 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0117425 |
| RPS12 | ribosomal protein S12 | 0.0117224 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0110248 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.010792 |
| RPS23 | ribosomal protein S23 | 0.00878296 |
| NCOR1 | nuclear receptor corepressor 1 | 0.00842403 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.00776722 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.00682361 |
| RPS25 | ribosomal protein S25 | 0.00656661 |
| ZNF292 | zinc finger protein 292 | 0.0065478 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.205077 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.173423 |
| VIM | vimentin | -0.16409 |
| CDH13 | cadherin 13 | -0.126882 |
| MT2A | metallothionein 2A | -0.12065 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.118382 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.11706 |
| STC1 | stanniocalcin 1 | -0.115149 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.113329 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.111378 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.110967 |
| PDLIM5 | PDZ and LIM domain 5 | -0.11085 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.107578 |
| HMGA2 | high mobility group AT-hook 2 | -0.0987194 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0876728 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0836511 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0807853 |
| AOPEP | aminopeptidase O (putative) | -0.0806774 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0783348 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0781984 |
| LAMA4 | laminin, alpha 4 | -0.075354 |
| NAV2 | neuron navigator 2 | -0.0709824 |
| H3-3B | H3.3 histone B | -0.0679873 |
| RPL37A | ribosomal protein L37a | -0.0640996 |
| VMP1 | vacuole membrane protein 1 | -0.0627269 |
| SLTM | SAFB-like, transcription modulator | -0.0626592 |
| SMYD3 | SET and MYND domain containing 3 | -0.0619588 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0614095 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0598147 |
| PKM | pyruvate kinase, muscle | -0.0588457 |
| PRKCA | protein kinase C, alpha | -0.0583706 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0567832 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0565401 |
| TXNRD1 | thioredoxin reductase 1 | -0.0528162 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0521291 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0517156 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0509339 |
| RPL35A | ribosomal protein L35a | -0.0501276 |
| DIAPH2 | diaphanous-related formin 2 | -0.0496016 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0484406 |
| FAM13A | family with sequence similarity 13, member A | -0.048151 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0473779 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0473442 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0471733 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0471055 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0455481 |
| RPL15 | ribosomal protein L15 | -0.0430837 |
| EXT1 | exostosin glycosyltransferase 1 | -0.041601 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0412543 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0412239 |
| MYOF | myoferlin | -0.040261 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0395957 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0389343 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.038384 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0374745 |
| RPS3 | ribosomal protein S3 | -0.0362653 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0361377 |
| COL5A1 | collagen, type V, alpha 1 | -0.0355109 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0340828 |
| PRKD3 | protein kinase D3 | -0.0339148 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0323604 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0318274 |
| SPAG9 | sperm associated antigen 9 | -0.0316811 |
| RPL34 | ribosomal protein L34 | -0.0314425 |
| NDRG1 | N-myc downstream regulated 1 | -0.03087 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.030139 |
| NOP58 | NOP58 ribonucleoprotein | -0.0277266 |
| RIGI | RNA sensor RIG-I | -0.0271552 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0265826 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.026564 |
| RPS8 | ribosomal protein S8 | -0.0253306 |
| EFNA5 | ephrin-A5 | -0.0240988 |
| RTN4 | reticulon 4 | -0.0234509 |
| VCL | vinculin | -0.0229038 |
| MED13 | mediator complex subunit 13 | -0.0225026 |
| TPM4 | tropomyosin 4 | -0.0221891 |
| GOLGA4 | golgin A4 | -0.0189709 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0187557 |
| RPL9 | ribosomal protein L9 | -0.0186992 |
| SSH2 | slingshot protein phosphatase 2 | -0.0169772 |
| USP34 | ubiquitin specific peptidase 34 | -0.0160399 |
| IGF2 | insulin-like growth factor 2 | -0.0157788 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0151502 |
| RPS6 | ribosomal protein S6 | -0.014864 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0140427 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0133562 |
| ATP9B | ATPase, class II, type 9B | -0.0122858 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0121933 |
| LMO7 | LIM domain 7 | -0.0113747 |
| MYO1E | myosin IE | -0.0113216 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0105553 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.00980902 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00940071 |
| NBEAL1 | neurobeachin-like 1 | -0.00929739 |
| LAMB3 | laminin, beta 3 | -0.00920693 |
| MCL1 | myeloid cell leukemia 1 | -0.00861942 |
| ENO1 | enolase 1, (alpha) | -0.00825818 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.00793548 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.00778594 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00727315 |
