| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Naproxen perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Naproxen_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.31495 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.11456 |
| UBC | ubiquitin C | 0.114363 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.102017 |
| EZR | ezrin | 0.091173 |
| PCBP2 | poly(rC) binding protein 2 | 0.0909569 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0811043 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0772009 |
| ENO1 | enolase 1, (alpha) | 0.0768273 |
| FLNB | filamin B, beta | 0.0721797 |
| GOLGA4 | golgin A4 | 0.0715609 |
| RPS2 | ribosomal protein S2 | 0.06671 |
| DUSP4 | dual specificity phosphatase 4 | 0.0648163 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0563227 |
| MKI67 | marker of proliferation Ki-67 | 0.0547671 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0537043 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0533936 |
| BRD2 | bromodomain containing 2 | 0.0507833 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0489687 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0466419 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0452825 |
| PLXNA1 | plexin A1 | 0.0438106 |
| FNIP1 | folliculin interacting protein 1 | 0.0416053 |
| NUP58 | nucleoporin 58 | 0.0415679 |
| AMOTL2 | angiomotin like 2 | 0.040728 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0401413 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0394602 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0389025 |
| BMP2K | BMP2 inducible kinase | 0.0379565 |
| LOXL3 | lysyl oxidase-like 3 | 0.0376956 |
| RPS27A | ribosomal protein S27a | 0.0375401 |
| RPL4 | ribosomal protein L4 | 0.0374441 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0370036 |
| PLK2 | polo-like kinase 2 | 0.0357202 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0355409 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0349688 |
| TMF1 | TATA element modulatory factor 1 | 0.0345926 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0343101 |
| RELA | v-rel avian reticuloendotheliosis viral oncogene homolog A | 0.03411 |
| EBNA1BP2 | EBNA1 binding protein 2 | 0.0340982 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0339828 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0337283 |
| PTK2 | protein tyrosine kinase 2 | 0.0336899 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0335808 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0333696 |
| SBF2 | SET binding factor 2 | 0.0329603 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0328102 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0322812 |
| SET | SET nuclear proto-oncogene | 0.0321254 |
| CENPF | centromere protein F, 350/400kDa | 0.0318741 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.031315 |
| PRELID2 | PRELI domain containing 2 | 0.0310555 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0307722 |
| ASPH | aspartate beta-hydroxylase | 0.0305639 |
| PNN | pinin, desmosome associated protein | 0.0303671 |
| PYGB | phosphorylase, glycogen; brain | 0.0300469 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0299283 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0295003 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0294511 |
| HDGF | hepatoma-derived growth factor | 0.029308 |
| SRPK2 | SRSF protein kinase 2 | 0.0288616 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0285451 |
| NBAS | neuroblastoma amplified sequence | 0.0283464 |
| RPL21 | ribosomal protein L21 | 0.0273299 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0273286 |
| ATP13A3 | ATPase type 13A3 | 0.0272904 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0272824 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.027132 |
| RBM39 | RNA binding motif protein 39 | 0.0267747 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0265633 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0265326 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | 0.0261012 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.025977 |
| CALR | calreticulin | 0.0256151 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0255874 |
| TPM3 | tropomyosin 3 | 0.0253968 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0252106 |
| ANO6 | anoctamin 6 | 0.0251322 |
| TLN1 | talin 1 | 0.0247561 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0246971 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.0246498 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0245365 |
| YEATS2 | YEATS domain containing 2 | 0.0244702 |
| H1-4 | H1.4 linker histone, cluster member | 0.024424 |
| OGA | O-GlcNAcase | 0.0243048 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.024295 |
| USP34 | ubiquitin specific peptidase 34 | 0.0242759 |
| TPD52 | tumor protein D52 | 0.0239996 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0236534 |
| CKAP5 | cytoskeleton associated protein 5 | 0.023423 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0228513 |
| AHNAK | AHNAK nucleoprotein | 0.0226909 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0225755 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.0225242 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0223957 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0222458 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0222047 |
| TUBA1B | tubulin, alpha 1b | 0.0221196 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0220302 |
| CABIN1 | calcineurin binding protein 1 | 0.021959 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.201334 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.126082 |
| RPL35A | ribosomal protein L35a | -0.102046 |
| TMSB4X | thymosin beta 4, X-linked | -0.0904918 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0894891 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0882124 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0750521 |
| ANXA1 | annexin A1 | -0.0649837 |
| FOXP1 | forkhead box P1 | -0.0607377 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0603683 |
| RPLP0 | ribosomal protein, large, P0 | -0.0582719 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0581815 |
| RPL11 | ribosomal protein L11 | -0.0577009 |
| ACTG1 | actin gamma 1 | -0.0574609 |
| RPS19 | ribosomal protein S19 | -0.0572348 |
| RPLP1 | ribosomal protein, large, P1 | -0.0561785 |
| NBEA | neurobeachin | -0.0555109 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0552324 |
| EGFR | epidermal growth factor receptor | -0.0539235 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0466226 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0457209 |
| RPL27A | ribosomal protein L27a | -0.0452971 |
| RPL31 | ribosomal protein L31 | -0.0437552 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0434298 |
| B2M | beta-2-microglobulin | -0.0424563 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0420676 |
| RPS20 | ribosomal protein S20 | -0.0416842 |
| RPS24 | ribosomal protein S24 | -0.0414242 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0403611 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0402235 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0384716 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0383858 |
| CCND1 | cyclin D1 | -0.03778 |
| BMP10 | bone morphogenetic protein 10 | -0.0376062 |
| RPL34 | ribosomal protein L34 | -0.0368551 |
| PTMA | prothymosin, alpha | -0.0356435 |
| MSI2 | musashi RNA-binding protein 2 | -0.0354212 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0353604 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0352955 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0350008 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0348971 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0335629 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0330907 |
| MED13 | mediator complex subunit 13 | -0.0324062 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.032299 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0318133 |
| MATR3 | matrin 3 | -0.0315203 |
| HLA-B | major histocompatibility complex, class I, B | -0.030928 |
| RPL19 | ribosomal protein L19 | -0.0305801 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0295736 |
| PKM | pyruvate kinase, muscle | -0.0288968 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0285593 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0283517 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0283228 |
| OSMR | oncostatin M receptor | -0.0280858 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0277711 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0275952 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0275631 |
| RTN3 | reticulon 3 | -0.0270435 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0265826 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0263801 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0263518 |
| LDHA | lactate dehydrogenase A | -0.0263124 |
| RPL7A | ribosomal protein L7a | -0.0259754 |
| RPL12 | ribosomal protein L12 | -0.0259058 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.025902 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0257951 |
| RIGI | RNA sensor RIG-I | -0.0256268 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0255788 |
| RPS21 | ribosomal protein S21 | -0.0254785 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | -0.0253094 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0253026 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0243395 |
| RLF | rearranged L-myc fusion | -0.0242937 |
| PRDX2 | peroxiredoxin 2 | -0.0242263 |
| PGK1 | phosphoglycerate kinase 1 | -0.0241766 |
| RPL7 | ribosomal protein L7 | -0.0238751 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0238084 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.023735 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0237334 |
| RPS13 | ribosomal protein S13 | -0.0236977 |
| YBX1 | Y box binding protein 1 | -0.0236977 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0236504 |
| RPS28 | ribosomal protein S28 | -0.0234426 |
| TMEM41B | transmembrane protein 41B | -0.0233412 |
| TCF12 | transcription factor 12 | -0.0233335 |
| OLA1 | Obg-like ATPase 1 | -0.0232647 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.0232624 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0230877 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0230664 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0230315 |
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | -0.0227848 |
| S100A4 | S100 calcium binding protein A4 | -0.0224825 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0223143 |
| SQSTM1 | sequestosome 1 | -0.0222164 |
| ARF1 | ADP-ribosylation factor 1 | -0.0219564 |
| CERT1 | ceramide transporter 1 | -0.021933 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | -0.0218481 |
| RPS6 | ribosomal protein S6 | -0.0218216 |
| S100A6 | S100 calcium binding protein A6 | -0.0218136 |
