| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Naproxen perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Naproxen_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.220426 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.204569 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.142404 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.11196 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.100137 |
| MSN | moesin | 0.0882478 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0875 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0874663 |
| PCBP2 | poly(rC) binding protein 2 | 0.0871354 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0857992 |
| NAV2 | neuron navigator 2 | 0.0820149 |
| RPS12 | ribosomal protein S12 | 0.0816394 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0810531 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.076561 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0722633 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0714101 |
| CD44 | CD44 molecule (Indian blood group) | 0.0672727 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0653659 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0645001 |
| RPS2 | ribosomal protein S2 | 0.0631721 |
| FLNB | filamin B, beta | 0.0631156 |
| UBC | ubiquitin C | 0.0625445 |
| GOLGA4 | golgin A4 | 0.0623246 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0616703 |
| RPS6 | ribosomal protein S6 | 0.061293 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0610671 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0568567 |
| RTN4 | reticulon 4 | 0.0561472 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0553657 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0547453 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0539941 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0532605 |
| STC1 | stanniocalcin 1 | 0.0525386 |
| FLNA | filamin A, alpha | 0.0525044 |
| RPS27A | ribosomal protein S27a | 0.0522698 |
| EGR1 | early growth response 1 | 0.0519607 |
| DST | dystonin | 0.051878 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0513644 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0511565 |
| JMJD1C | jumonji domain containing 1C | 0.0511174 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0498704 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0483712 |
| MLPH | melanophilin | 0.0481181 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0480199 |
| DUSP5 | dual specificity phosphatase 5 | 0.0476888 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0471784 |
| IL6ST | interleukin 6 signal transducer | 0.0470612 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0464048 |
| FRMD4A | FERM domain containing 4A | 0.0459215 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0457847 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0456916 |
| B2M | beta-2-microglobulin | 0.0455048 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0455034 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0454652 |
| SYAP1 | synapse associated protein 1 | 0.0449368 |
| VMP1 | vacuole membrane protein 1 | 0.0446042 |
| CENPF | centromere protein F, 350/400kDa | 0.0437196 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0434782 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0426105 |
| TPM3 | tropomyosin 3 | 0.0425321 |
| SEPTIN9 | septin 9 | 0.0423587 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0419083 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0411601 |
| CLIC4 | chloride intracellular channel 4 | 0.040657 |
| CCNL1 | cyclin L1 | 0.0405707 |
| ENO1 | enolase 1, (alpha) | 0.0384803 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0384038 |
| NAV1 | neuron navigator 1 | 0.0369602 |
| VCAN | versican | 0.036448 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0361875 |
| MCL1 | myeloid cell leukemia 1 | 0.0358105 |
| SET | SET nuclear proto-oncogene | 0.0356267 |
| RPL4 | ribosomal protein L4 | 0.0355283 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0355185 |
| DSTN | destrin (actin depolymerizing factor) | 0.0352244 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0351175 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0350599 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0348946 |
| PRELID2 | PRELI domain containing 2 | 0.0346476 |
| USP47 | ubiquitin specific peptidase 47 | 0.0346125 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0345606 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0345058 |
| MKI67 | marker of proliferation Ki-67 | 0.0343635 |
| NONO | non-POU domain containing, octamer-binding | 0.0343143 |
| RPL21 | ribosomal protein L21 | 0.0337036 |
| RPL9 | ribosomal protein L9 | 0.0329589 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0328581 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0326388 |
| AXL | AXL receptor tyrosine kinase | 0.032632 |
| RBM39 | RNA binding motif protein 39 | 0.0315957 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0314664 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0312089 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0307029 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0303884 |
| RAI1 | retinoic acid induced 1 | 0.0302117 |
| BRD2 | bromodomain containing 2 | 0.0300427 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | 0.0298546 |
| TUBA1B | tubulin, alpha 1b | 0.0295364 |
| TAPBP | TAP binding protein (tapasin) | 0.0295263 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0294992 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.129199 |
| VIM | vimentin | -0.118659 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.118464 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0953527 |
| IER3 | immediate early response 3 | -0.0927697 |
| PGK1 | phosphoglycerate kinase 1 | -0.0871962 |
| FTL | ferritin, light polypeptide | -0.0755011 |
| FN1 | fibronectin 1 | -0.073774 |
| RPS24 | ribosomal protein S24 | -0.0708628 |
| BICC1 | BicC family RNA binding protein 1 | -0.0692803 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0671977 |
| RPL35A | ribosomal protein L35a | -0.0608815 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0548322 |
| GLIS3 | GLIS family zinc finger 3 | -0.0536985 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0503952 |
| RPLP1 | ribosomal protein, large, P1 | -0.0501751 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0495681 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0493111 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0470455 |
| GPC6 | glypican 6 | -0.0465359 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.045733 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0431406 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.042243 |
| HLA-C | major histocompatibility complex, class I, C | -0.0422175 |
| RPS4X | ribosomal protein S4, X-linked | -0.0417386 |
| DEK | DEK proto-oncogene | -0.0370739 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0359964 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0353516 |
| NDRG1 | N-myc downstream regulated 1 | -0.0350507 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0350157 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0348859 |
| WTAP | Wilms tumor 1 associated protein | -0.0346526 |
| INTS6 | integrator complex subunit 6 | -0.0336985 |
| RPLP0 | ribosomal protein, large, P0 | -0.0331085 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -0.030532 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0304181 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0303137 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0302976 |
| PDE10A | phosphodiesterase 10A | -0.0302806 |
| RAB1A | RAB1A, member RAS oncogene family | -0.028989 |
| HMGA2 | high mobility group AT-hook 2 | -0.0286586 |
| RPL38 | ribosomal protein L38 | -0.028631 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0282828 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0278628 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0276409 |
| CTSB | cathepsin B | -0.0274071 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0265261 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0259247 |
| THBS2 | thrombospondin 2 | -0.0252304 |
| TMEM132D | transmembrane protein 132D | -0.0249212 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | -0.0246071 |
| FAM162A | family with sequence similarity 162, member A | -0.0240971 |
| AUTS2 | autism susceptibility candidate 2 | -0.023665 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.023173 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0231575 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.0230805 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0229338 |
| ACTG1 | actin gamma 1 | -0.0229311 |
| RPS20 | ribosomal protein S20 | -0.0227451 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0222094 |
| CRY1 | cryptochrome circadian clock 1 | -0.0220079 |
| CAVIN1 | caveolae associated protein 1 | -0.0218258 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0215366 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0214896 |
| HBS1L | HBS1-like translational GTPase | -0.0211485 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0211035 |
| KIF13A | kinesin family member 13A | -0.0210858 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | -0.0210816 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0209549 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0209488 |
| WDR45B | WD repeat domain 45B | -0.0209292 |
| HMGA1 | high mobility group AT-hook 1 | -0.0208737 |
| RASAL2 | RAS protein activator like 2 | -0.020849 |
| RPL39 | ribosomal protein L39 | -0.0207595 |
| ADM | adrenomedullin | -0.0207234 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0205284 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.020264 |
| TCEAL9 | transcription elongation factor A like 9 | -0.0200332 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0199385 |
| TUBB | tubulin, beta class I | -0.0199157 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0198917 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0198662 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0198478 |
| TKT | transketolase | -0.0197203 |
| RPL12 | ribosomal protein L12 | -0.0197083 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | -0.0197047 |
| SFTPA2 | surfactant protein A2 | -0.0195456 |
| TRIM55 | tripartite motif containing 55 | -0.0194846 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0194681 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0194469 |
| ASTN2 | astrotactin 2 | -0.0194364 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0193504 |
| PATL1 | protein associated with topoisomerase II homolog 1 (yeast) | -0.0191136 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.018983 |
| ERBIN | erbb2 interacting protein | -0.0189107 |
| C3 | complement component 3 | -0.0188333 |
| RNF213 | ring finger protein 213 | -0.0187851 |
| BSG | basigin (Ok blood group) | -0.0187296 |
| MORF4L2 | mortality factor 4 like 2 | -0.0186549 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0185682 |
