| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Naproxen perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Naproxen_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.136283 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.108955 |
| UBC | ubiquitin C | 0.103559 |
| GOLGA4 | golgin A4 | 0.0942963 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0877019 |
| SET | SET nuclear proto-oncogene | 0.0845023 |
| PCBP2 | poly(rC) binding protein 2 | 0.0843608 |
| RPS27A | ribosomal protein S27a | 0.0742325 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.066852 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0654423 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0633358 |
| VIM | vimentin | 0.0632547 |
| FMNL2 | formin-like 2 | 0.0613551 |
| RBM39 | RNA binding motif protein 39 | 0.0572135 |
| RPL4 | ribosomal protein L4 | 0.0564809 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0551418 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.0546121 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0522642 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0511505 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0502498 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0481499 |
| SNX14 | sorting nexin 14 | 0.0481072 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0480757 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0478445 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0469805 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0463339 |
| TPM3 | tropomyosin 3 | 0.0459796 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0447876 |
| H1-4 | H1.4 linker histone, cluster member | 0.0443965 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0440797 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0440551 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.04343 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0429828 |
| PAPOLA | poly(A) polymerase alpha | 0.0428262 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0425798 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0422893 |
| ZNF292 | zinc finger protein 292 | 0.0412422 |
| OGA | O-GlcNAcase | 0.0410727 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0409031 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0407525 |
| TPR | translocated promoter region, nuclear basket protein | 0.0406526 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0398917 |
| FLNB | filamin B, beta | 0.0396721 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0394456 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0392467 |
| CLASP1 | cytoplasmic linker associated protein 1 | 0.0383958 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0379706 |
| IL6ST | interleukin 6 signal transducer | 0.0374723 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0368408 |
| PRELID2 | PRELI domain containing 2 | 0.0368113 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0361325 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0361127 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0357793 |
| ZFR | zinc finger RNA binding protein | 0.0357434 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | 0.0355486 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0354873 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0352659 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0350431 |
| CD44 | CD44 molecule (Indian blood group) | 0.0349711 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0347648 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.0338677 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0338554 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0335966 |
| TMEM245 | transmembrane protein 245 | 0.0332467 |
| TOP1 | topoisomerase (DNA) I | 0.0327678 |
| FLNA | filamin A, alpha | 0.0325726 |
| CCDC88A | coiled-coil domain containing 88A | 0.0325541 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.0324026 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0323115 |
| RPL26 | ribosomal protein L26 | 0.0322943 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0322777 |
| PPP6R2 | protein phosphatase 6, regulatory subunit 2 | 0.0322178 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0319566 |
| ZNF670 | zinc finger protein 670 | 0.0319273 |
| PRRC2B | proline-rich coiled-coil 2B | 0.031676 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0316415 |
| VMP1 | vacuole membrane protein 1 | 0.0315692 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.031451 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0313474 |
| SAFB2 | scaffold attachment factor B2 | 0.0312868 |
| RBM33 | RNA binding motif protein 33 | 0.0309551 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0308341 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0308307 |
| HDLBP | high density lipoprotein binding protein | 0.0308208 |
| RPL10A | ribosomal protein L10a | 0.03074 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0305793 |
| RPS17 | ribosomal protein S17 | 0.0305712 |
| CEP250 | centrosomal protein 250kDa | 0.0302603 |
| RPS2 | ribosomal protein S2 | 0.0302574 |
| SMAD3 | SMAD family member 3 | 0.0301481 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0301428 |
| YY1 | YY1 transcription factor | 0.0301021 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0299301 |
| RPL5 | ribosomal protein L5 | 0.0298367 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0298133 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0295699 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0294715 |
| NONO | non-POU domain containing, octamer-binding | 0.029396 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0293869 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0289941 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.128679 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.107004 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0841722 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0600852 |
| ACTG1 | actin gamma 1 | -0.0543975 |
| ANXA2 | annexin A2 | -0.051788 |
| DST | dystonin | -0.0489206 |
| INTS6 | integrator complex subunit 6 | -0.0480559 |
| RPLP0 | ribosomal protein, large, P0 | -0.0463188 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0453637 |
| GPC6 | glypican 6 | -0.0432884 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0428046 |
| ERBIN | erbb2 interacting protein | -0.0423419 |
| IGF2 | insulin-like growth factor 2 | -0.0422277 |
| TMSB10 | thymosin beta 10 | -0.0415273 |
| CCNH | cyclin H | -0.0404524 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0403546 |
| PRKCA | protein kinase C, alpha | -0.0392651 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 | -0.0390063 |
| S100A10 | S100 calcium binding protein A10 | -0.0388551 |
| POTEF | POTE ankyrin domain family, member F | -0.0387725 |
| BSG | basigin (Ok blood group) | -0.0381936 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.037846 |
| SLC36A4 | solute carrier family 36 (proton/amino acid symporter), member 4 | -0.0373855 |
| MED13L | mediator complex subunit 13-like | -0.0368735 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0363428 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | -0.0359053 |
| NDRG1 | N-myc downstream regulated 1 | -0.035605 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0349591 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0349319 |
| TMEM123 | transmembrane protein 123 | -0.0348151 |
| VCL | vinculin | -0.0346371 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0337993 |
| PRR16 | proline rich 16 | -0.0329039 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0321346 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0321027 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0320012 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0319397 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0313686 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0312266 |
| RDX | radixin | -0.030779 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0307379 |
| CEP290 | centrosomal protein 290kDa | -0.0305998 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0302012 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0300889 |
| SMAD2 | SMAD family member 2 | -0.030036 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.029968 |
| USP34 | ubiquitin specific peptidase 34 | -0.029902 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0298502 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0297501 |
| MYADM | myeloid-associated differentiation marker | -0.0296183 |
| OSMR | oncostatin M receptor | -0.0294124 |
| MAP1B | microtubule-associated protein 1B | -0.0288601 |
| SP100 | SP100 nuclear antigen | -0.0287525 |
| PGK1 | phosphoglycerate kinase 1 | -0.0287417 |
| CDC73 | cell division cycle 73 | -0.0285096 |
| SQSTM1 | sequestosome 1 | -0.028397 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0280508 |
| PHF21A | PHD finger protein 21A | -0.0279231 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | -0.0277053 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0277038 |
| PCDH7 | protocadherin 7 | -0.0275213 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0274943 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | -0.0273866 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0273764 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.027361 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0273516 |
| RAB2A | RAB2A, member RAS oncogene family | -0.027316 |
| MT2A | metallothionein 2A | -0.0272337 |
| TRAPPC8 | trafficking protein particle complex 8 | -0.026902 |
| SEPTIN7 | septin 7 | -0.0265889 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0265448 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0264734 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0263 |
| SS18 | synovial sarcoma translocation, chromosome 18 | -0.0262439 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0261341 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0259403 |
| IDS | iduronate 2-sulfatase | -0.0259364 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0259172 |
| SETX | senataxin | -0.025661 |
| PRMT2 | protein arginine methyltransferase 2 | -0.0256415 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0256281 |
| RPS23 | ribosomal protein S23 | -0.0255377 |
| ZNF217 | zinc finger protein 217 | -0.0254036 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0252725 |
| SEC24D | SEC24 family member D | -0.0251011 |
| CEP350 | centrosomal protein 350kDa | -0.0250312 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0249614 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.024848 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0246651 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0245626 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0245329 |
| RASAL2 | RAS protein activator like 2 | -0.0245288 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0244953 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0243012 |
| TOP6BL | TOP6B like initiator of meiotic double strand breaks | -0.0242232 |
| CERT1 | ceramide transporter 1 | -0.0240097 |
| BBX | bobby sox homolog (Drosophila) | -0.0239221 |
| COMMD10 | COMM domain containing 10 | -0.0238609 |
| SOGA1 | suppressor of glucose, autophagy associated 1 | -0.0238186 |
