| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Naproxen perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Naproxen_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.181695 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.154487 |
| VIM | vimentin | 0.119304 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0891075 |
| PRRC2C | proline-rich coiled-coil 2C | 0.087291 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0847014 |
| GOLGA4 | golgin A4 | 0.0825459 |
| VEGFA | vascular endothelial growth factor A | 0.0783867 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0779516 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0722522 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0720452 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0717326 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.067716 |
| PKM | pyruvate kinase, muscle | 0.061902 |
| TMEM165 | transmembrane protein 165 | 0.0597037 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0584824 |
| SMOX | spermine oxidase | 0.0583375 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0582787 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0575234 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.056501 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0563371 |
| CALR | calreticulin | 0.0562206 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0551476 |
| TPM3 | tropomyosin 3 | 0.0549059 |
| HDGF | hepatoma-derived growth factor | 0.0546561 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0532972 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0518655 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0512236 |
| ENO1 | enolase 1, (alpha) | 0.0494982 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0491988 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0491054 |
| TLN1 | talin 1 | 0.0483425 |
| FLNA | filamin A, alpha | 0.0479721 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0476341 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.047399 |
| LOC112694756 | uncharaterized LOC112694756 | 0.047055 |
| RBM39 | RNA binding motif protein 39 | 0.0466009 |
| ASPH | aspartate beta-hydroxylase | 0.0464137 |
| TPR | translocated promoter region, nuclear basket protein | 0.0461948 |
| RACK1 | receptor for activated C kinase 1 | 0.0458301 |
| RNF145 | ring finger protein 145 | 0.0454325 |
| EFNA5 | ephrin-A5 | 0.0448667 |
| ITGA1 | integrin, alpha 1 | 0.0444322 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0435099 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.042652 |
| PNN | pinin, desmosome associated protein | 0.0424429 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.041225 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0407325 |
| SFTPA2 | surfactant protein A2 | 0.0403846 |
| RPS2 | ribosomal protein S2 | 0.0400769 |
| RPL26 | ribosomal protein L26 | 0.0400204 |
| CLTC | clathrin, heavy chain (Hc) | 0.0389736 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0385099 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0382943 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.038262 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0382413 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0379157 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0378919 |
| FAT1 | FAT atypical cadherin 1 | 0.0377287 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0370184 |
| RPS6 | ribosomal protein S6 | 0.0367263 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0358216 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0357963 |
| CENPF | centromere protein F, 350/400kDa | 0.0357918 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0353685 |
| TMSB10 | thymosin beta 10 | 0.0351973 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0348835 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0346853 |
| PRELID2 | PRELI domain containing 2 | 0.0344485 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0340579 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0337962 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0337576 |
| RTN4 | reticulon 4 | 0.0337428 |
| KIF5B | kinesin family member 5B | 0.0333428 |
| PCBP2 | poly(rC) binding protein 2 | 0.0330241 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0329717 |
| FAM13A | family with sequence similarity 13, member A | 0.0328735 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0320687 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0319741 |
| RO60 | Ro60, Y RNA binding protein | 0.0319076 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0316863 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0314884 |
| SFXN1 | sideroflexin 1 | 0.031357 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0312371 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0311857 |
| PAPOLA | poly(A) polymerase alpha | 0.0311804 |
| ETV6 | ets variant 6 | 0.0309061 |
| NDRG1 | N-myc downstream regulated 1 | 0.0308626 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0303737 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0303498 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0302588 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0300316 |
| TMF1 | TATA element modulatory factor 1 | 0.0293575 |
| RPL3 | ribosomal protein L3 | 0.0291848 |
| FNIP1 | folliculin interacting protein 1 | 0.0290167 |
| ATN1 | atrophin 1 | 0.0288043 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0286172 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0286081 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0281783 |
| CREBRF | CREB3 regulatory factor | 0.0281388 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.166017 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.148186 |
| NRG1 | neuregulin 1 | -0.105111 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.102721 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0899609 |
| CANX | calnexin | -0.0884485 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0806147 |
| MT2A | metallothionein 2A | -0.0790163 |
| FN1 | fibronectin 1 | -0.0743004 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.053153 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0513354 |
| IER3 | immediate early response 3 | -0.0505805 |
| RPL35A | ribosomal protein L35a | -0.0492331 |
| HLA-B | major histocompatibility complex, class I, B | -0.0438909 |
| TMEM156 | transmembrane protein 156 | -0.0415637 |
| VCL | vinculin | -0.0410579 |
| SVIL | supervillin | -0.0380248 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0378911 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0377357 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0362858 |
| RHEB | Ras homolog enriched in brain | -0.0347665 |
| INTS6 | integrator complex subunit 6 | -0.0346758 |
| RPS24 | ribosomal protein S24 | -0.0344154 |
| H1-0 | H1.0 linker histone | -0.0333423 |
| SYT1 | synaptotagmin I | -0.0333373 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0331317 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0324385 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0323416 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0322312 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0321361 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0321197 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0317595 |
| PGK1 | phosphoglycerate kinase 1 | -0.0313851 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0313291 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0310939 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0302846 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0302414 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.030162 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0300719 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0296536 |
| KLHL5 | kelch-like family member 5 | -0.0294612 |
| RPLP1 | ribosomal protein, large, P1 | -0.0292018 |
| MT1X | metallothionein 1X | -0.0289334 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0286858 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0283423 |
| PELO | pelota homolog (Drosophila) | -0.0283141 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0279344 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0278116 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0274048 |
| TXNRD1 | thioredoxin reductase 1 | -0.0272089 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0267738 |
| THBS1 | thrombospondin 1 | -0.0266801 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0261693 |
| YBX3 | Y box binding protein 3 | -0.0261049 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0257954 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0252847 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0249479 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.0247996 |
| FOXP1 | forkhead box P1 | -0.0245194 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0243394 |
| OLA1 | Obg-like ATPase 1 | -0.0240588 |
| RPL34 | ribosomal protein L34 | -0.0240124 |
| MTPN | myotrophin | -0.0239615 |
| DNM1L | dynamin 1-like | -0.0239137 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0235583 |
| ZNF217 | zinc finger protein 217 | -0.0234398 |
| NTN4 | netrin 4 | -0.0234327 |
| AEBP2 | AE binding protein 2 | -0.0232823 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0232255 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0230884 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0230008 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.022887 |
| MAP1B | microtubule-associated protein 1B | -0.0227025 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0224633 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0224277 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.0221975 |
| RPLP0 | ribosomal protein, large, P0 | -0.0218729 |
| CPLANE1 | ciliogenesis and planar polarity effector complex subunit 1 | -0.0217928 |
| AFTPH | aftiphilin | -0.0217584 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0214617 |
| S100A10 | S100 calcium binding protein A10 | -0.021417 |
| FBN1 | fibrillin 1 | -0.0213171 |
| CYRIB | CYFIP related Rac1 interactor B | -0.021162 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.021055 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0204223 |
| ZNF207 | zinc finger protein 207 | -0.0204099 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0203706 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0202667 |
| RPS20 | ribosomal protein S20 | -0.0201498 |
| MORF4L2 | mortality factor 4 like 2 | -0.0201366 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0200029 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0197158 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0196079 |
| RPS5 | ribosomal protein S5 | -0.0195798 |
| RPL19 | ribosomal protein L19 | -0.0195597 |
| HPCAL1 | hippocalcin-like 1 | -0.0195122 |
| PDLIM5 | PDZ and LIM domain 5 | -0.019413 |
| SSH1 | slingshot protein phosphatase 1 | -0.0193867 |
| RNF213 | ring finger protein 213 | -0.0193081 |
| CCDC138 | coiled-coil domain containing 138 | -0.0193073 |
