Narcolepsy Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A sleep disorder that involves an excessive urge to sleep at inappropriate times, such as while at work. (Human Disease Ontology, DOID_8986)
External Link https://www.disgenet.org/browser/0/1/0/C0027404
Similar Terms
Downloads & Tools

Genes

268 genes associated with the disease Narcolepsy in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACSS1 acyl-CoA synthetase short-chain family member 1
ADAMTSL3 ADAMTS-like 3
AGBL1 ATP/GTP binding protein-like 1
AGTR1 angiotensin II receptor, type 1
AK5 adenylate kinase 5
AKAP6 A kinase (PRKA) anchor protein 6
ALKBH8 alkB, alkylation repair homolog 8 (E. coli)
ANO3 anoctamin 3
ANTXR2 anthrax toxin receptor 2
ASIC2 acid sensing (proton gated) ion channel 2
ASTN1 astrotactin 1
ATF6 activating transcription factor 6
ATG5 autophagy related 5
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
ATXN3 ataxin 3
BARX2 BARX homeobox 2
BBS9 Bardet-Biedl syndrome 9
BCR breakpoint cluster region
BLMH bleomycin hydrolase
BTNL2 butyrophilin-like 2
C6ORF10 chromosome 6 open reading frame 10
C8ORF34 chromosome 8 open reading frame 34
CA10 carbonic anhydrase X
CACNG2 calcium channel, voltage-dependent, gamma subunit 2
CATSPER4 cation channel, sperm associated 4
CCDC68 coiled-coil domain containing 68
CCR1 chemokine (C-C motif) receptor 1
CCR3 chemokine (C-C motif) receptor 3
CCS copper chaperone for superoxide dismutase
CD200R1 CD200 receptor 1
CD40LG CD40 ligand
CDK8 cyclin-dependent kinase 8
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CENPC centromere protein C
CEP112 centrosomal protein 112kDa
CHKB choline kinase beta
CIITA class II, major histocompatibility complex, transactivator
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLOCK clock circadian regulator
COL14A1 collagen, type XIV, alpha 1
COLGALT1 collagen beta(1-O)galactosyltransferase 1
COMT catechol-O-methyltransferase
CPT1B carnitine palmitoyltransferase 1B (muscle)
CRP C-reactive protein, pentraxin-related
CSF3 colony stimulating factor 3 (granulocyte)
CSMD3 CUB and Sushi multiple domains 3
CTNNA2 catenin (cadherin-associated protein), alpha 2
CTNND2 catenin (cadherin-associated protein), delta 2
CTSH cathepsin H
CXCL8 chemokine (C-X-C motif) ligand 8
CYB5B cytochrome b5 type B (outer mitochondrial membrane)
DAP3 death associated protein 3
DCDC2C doublecortin domain containing 2C
DCHS1 dachsous cadherin-related 1
DDAH1 dimethylarginine dimethylaminohydrolase 1
DENND3 DENN/MADD domain containing 3
DHODH dihydroorotate dehydrogenase (quinone)
DLGAP1 discs, large (Drosophila) homolog-associated protein 1
DLGAP2 discs, large (Drosophila) homolog-associated protein 2
DNAH8 dynein, axonemal, heavy chain 8
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DPP10 dipeptidyl-peptidase 10 (non-functional)
DPP6 dipeptidyl-peptidase 6
DPYD dihydropyrimidine dehydrogenase
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1
EDNRA endothelin receptor type A
EGFLAM EGF-like, fibronectin type III and laminin G domains
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EIF3G eukaryotic translation initiation factor 3, subunit G
ELMO1 engulfment and cell motility 1
EPHB1 EPH receptor B1
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
ERI1 exoribonuclease 1
FAM171A1 family with sequence similarity 171, member A1
FAM179A family with sequence similarity 179, member A
FAM3D family with sequence similarity 3, member D
FBXO15 F-box protein 15
FGF10 fibroblast growth factor 10
FGF21 fibroblast growth factor 21
FHIT fragile histidine triad
FHOD3 formin homology 2 domain containing 3
FOLR1 folate receptor 1 (adult)
FOXP2 forkhead box P2
FREM2 FRAS1 related extracellular matrix protein 2
FRMPD2 FERM and PDZ domain containing 2
FRY furry homolog (Drosophila)
FSTL5 follistatin-like 5
FXN frataxin
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GCG glucagon
GDNF glial cell derived neurotrophic factor
GH1 growth hormone 1
GHRH growth hormone releasing hormone
GLIS3 GLIS family zinc finger 3
GLP1R glucagon-like peptide 1 receptor
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GPC5 glypican 5
GRID1 glutamate receptor, ionotropic, delta 1
GRM5 glutamate receptor, metabotropic 5
GRM8 glutamate receptor, metabotropic 8
HCRT hypocretin (orexin) neuropeptide precursor
HCRTR1 hypocretin (orexin) receptor 1
HCRTR2 hypocretin (orexin) receptor 2
HDAC9 histone deacetylase 9
HDC histidine decarboxylase
HINT3 histidine triad nucleotide binding protein 3
HIST1H2AC histone cluster 1, H2ac
HLA-A major histocompatibility complex, class I, A
HLA-DOB major histocompatibility complex, class II, DO beta
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HLA-F major histocompatibility complex, class I, F
HRH3 histamine receptor H3
HS6ST3 heparan sulfate 6-O-sulfotransferase 3
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNA17 interferon, alpha 17
IFNA2 interferon, alpha 2
IFNG interferon, gamma
ITCH itchy E3 ubiquitin protein ligase
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
JAKMIP2 janus kinase and microtubule interacting protein 2
JPH1 junctophilin 1
KALRN kalirin, RhoGEF kinase
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4
KIAA0922 KIAA0922
KLF12 Kruppel-like factor 12
LEP leptin
LOC285423 uncharacterized LOC285423
LRRC4C leucine rich repeat containing 4C
LRRC7 leucine rich repeat containing 7
LRRN1 leucine rich repeat neuronal 1
LYRM4 LYR motif containing 4
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAOA monoamine oxidase A
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MCC mutated in colorectal cancers
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MMP26 matrix metallopeptidase 26
MOG myelin oligodendrocyte glycoprotein
MRAS muscle RAS oncogene homolog
MRPL24 mitochondrial ribosomal protein L24
MTUS2 microtubule associated tumor suppressor candidate 2
MX2 MX dynamin-like GTPase 2
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NDST3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFRKB nuclear factor related to kappaB binding protein
NKAIN2 Na+/K+ transporting ATPase interacting 2
NKAIN3 Na+/K+ transporting ATPase interacting 3
NOL4 nucleolar protein 4
NOTCH4 notch 4
NOX4 NADPH oxidase 4
NPFFR2 neuropeptide FF receptor 2
NRXN1 neurexin 1
NT5DC1 5'-nucleotidase domain containing 1
NUP37 nucleoporin 37kDa
NXPH1 neurexophilin 1
OXR1 oxidation resistance 1
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
P2RX6 purinergic receptor P2X, ligand gated ion channel, 6
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
P2RY11 purinergic receptor P2Y, G-protein coupled, 11
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PALLD palladin, cytoskeletal associated protein
PARK2 parkin RBR E3 ubiquitin protein ligase
PDE4B phosphodiesterase 4B, cAMP-specific
PDE7B phosphodiesterase 7B
PDYN prodynorphin
PENK proenkephalin
PHF20 PHD finger protein 20
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLB1 phospholipase B1
POLE polymerase (DNA directed), epsilon, catalytic subunit
POLI polymerase (DNA directed) iota
PPAN peter pan homolog (Drosophila)
PPAN-P2RY11 PPAN-P2RY11 readthrough
PPARA peroxisome proliferator-activated receptor alpha
PRCP prolylcarboxypeptidase (angiotensinase C)
PSG5 pregnancy specific beta-1-glycoprotein 5
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTPRD protein tyrosine phosphatase, receptor type, D
PYROXD2 pyridine nucleotide-disulphide oxidoreductase domain 2
QRFP pyroglutamylated RFamide peptide
RAD50 RAD50 homolog (S. cerevisiae)
RANGAP1 Ran GTPase activating protein 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBM45 RNA binding motif protein 45
RBMS3 RNA binding motif, single stranded interacting protein 3
REM1 RAS (RAD and GEM)-like GTP-binding 1
RIT2 Ras-like without CAAX 2
RNGTT RNA guanylyltransferase and 5'-phosphatase
RYR2 ryanodine receptor 2 (cardiac)
SALL4 spalt-like transcription factor 4
SDK1 sidekick cell adhesion molecule 1
SERAC1 serine active site containing 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SFRP1 secreted frizzled-related protein 1
SHC4 SHC (Src homology 2 domain containing) family, member 4
SHKBP1 SH3KBP1 binding protein 1
SKOR1 SKI family transcriptional corepressor 1
SLC14A2 solute carrier family 14 (urea transporter), member 2
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SNX29 sorting nexin 29
SOCS2 suppressor of cytokine signaling 2
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
STIM1 stromal interaction molecule 1
SUMF1 sulfatase modifying factor 1
SUN5 Sad1 and UNC84 domain containing 5
SWAP70 SWAP switching B-cell complex 70kDa subunit
TAAR1 trace amine associated receptor 1
TAC1 tachykinin, precursor 1
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TCERG1 transcription elongation regulator 1
TENM2 teneurin transmembrane protein 2
TF transferrin
TIAM1 T-cell lymphoma invasion and metastasis 1
TJP1 tight junction protein 1
TMEM108 transmembrane protein 108
TMEM132B transmembrane protein 132B
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TRA T cell receptor alpha locus
TRH thyrotropin-releasing hormone
TRIB2 tribbles pseudokinase 2
TRIM9 tripartite motif containing 9
UBXN2B UBX domain protein 2B
UNC5D unc-5 homolog D (C. elegans)
VAT1L vesicle amine transport 1-like
VAV1 vav 1 guanine nucleotide exchange factor
VAV2 vav 2 guanine nucleotide exchange factor
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WDR48 WD repeat domain 48
ZGLP1 zinc finger, GATA-like protein 1
ZNF365 zinc finger protein 365
ZNF385D zinc finger protein 385D
ZYG11B zyg-11 family member B, cell cycle regulator