Nasopharyngitis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A nasopharyngeal disease which involves inflammation of the nasal passages and upper part of the pharynx. (Human Disease Ontology, DOID_10460)
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Genes

333 genes co-occuring with the disease Nasopharyngitis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
DPP4 dipeptidyl-peptidase 4 2.644
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 2.634
IL17A interleukin 17A 2.631
JAK1 Janus kinase 1 2.496
TYK2 tyrosine kinase 2 2.473
JAK3 Janus kinase 3 2.426
TNF tumor necrosis factor 2.366
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.344
PCSK9 proprotein convertase subtilisin/kexin type 9 2.304
IL13 interleukin 13 2.286
IL31 interleukin 31 2.272
IL17F interleukin 17F 2.26
IL5 interleukin 5 2.246
GCG glucagon 2.245
CRP C-reactive protein, pentraxin-related 2.229
PDE4A phosphodiesterase 4A, cAMP-specific 2.224
IL17RA interleukin 17 receptor A 2.221
IL4 interleukin 4 2.21
JAK2 Janus kinase 2 2.18
IL23A interleukin 23, alpha subunit p19 2.169
IL22 interleukin 22 2.167
GLP1R glucagon-like peptide 1 receptor 2.158
IL6 interleukin 6 2.138
IL5RA interleukin 5 receptor, alpha 2.11
IFNB1 interferon, beta 1, fibroblast 2.108
GIP gastric inhibitory polypeptide 2.092
INS insulin 2.092
TSLP thymic stromal lymphopoietin 2.074
IL4R interleukin 4 receptor 2.062
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 2.04
CD4 CD4 molecule 2.029
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 2.021
IFNG interferon, gamma 2.012
PDE5A phosphodiesterase 5A, cGMP-specific 2.009
PPIG peptidylprolyl isomerase G (cyclophilin G) 1.986
DPP8 dipeptidyl-peptidase 8 1.976
S1PR5 sphingosine-1-phosphate receptor 5 1.919
DPP9 dipeptidyl-peptidase 9 1.916
IL25 interleukin 25 1.915
APOB apolipoprotein B 1.907
SI sucrase-isomaltase (alpha-glucosidase) 1.902
MGAM maltase-glucoamylase 1.897
IL1B interleukin 1, beta 1.896
DCLRE1A DNA cross-link repair 1A 1.893
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 1.893
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.86
FLG filaggrin 1.856
ALB albumin 1.839
FLG2 filaggrin family member 2 1.83
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1.823
CKMT1B creatine kinase, mitochondrial 1B 1.822
CKM creatine kinase, muscle 1.821
CKB creatine kinase, brain 1.819
IL17C interleukin 17C 1.812
IL10 interleukin 10 1.805
CD8A CD8a molecule 1.805
CCL26 chemokine (C-C motif) ligand 26 1.796
S1PR1 sphingosine-1-phosphate receptor 1 1.778
CCL17 chemokine (C-C motif) ligand 17 1.776
IL31RA interleukin 31 receptor A 1.77
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.766
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.766
IL2 interleukin 2 1.763
SPIRE1 spire-type actin nucleation factor 1 1.757
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.737
IL13RA1 interleukin 13 receptor, alpha 1 1.728
SPIRE2 spire-type actin nucleation factor 2 1.727
EGLN3 egl-9 family hypoxia-inducible factor 3 1.705
IL33 interleukin 33 1.702
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) 1.702
BORA bora, aurora kinase A activator 1.701
EGLN2 egl-9 family hypoxia-inducible factor 2 1.699
IL1A interleukin 1, alpha 1.696
S1PR4 sphingosine-1-phosphate receptor 4 1.692
IFNA1 interferon, alpha 1 1.69
EPO erythropoietin 1.684
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 1.679
SEPTIN3 septin 3 1.676
ACE angiotensin I converting enzyme 1.667
MAOB monoamine oxidase B 1.665
ANGPTL3 angiopoietin-like 3 1.657
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled 1.652
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 1.651
BTK Bruton agammaglobulinemia tyrosine kinase 1.638
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.636
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.63
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 1.628
DHODH dihydroorotate dehydrogenase (quinone) 1.623
CXCL8 chemokine (C-X-C motif) ligand 8 1.621
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 1.61
CD19 CD19 molecule 1.608
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.6
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.6
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.6
IL23R interleukin 23 receptor 1.597
EGLN1 egl-9 family hypoxia-inducible factor 1 1.591
S1PR3 sphingosine-1-phosphate receptor 3 1.588
IL36R interleukin 36 receptor 1.586
POSTN periostin, osteoblast specific factor 1.585
THPO thrombopoietin 1.583
IL9 interleukin 9 1.579
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 1.57
IL7 interleukin 7 1.556
TAC1 tachykinin, precursor 1 1.556
FCGRT Fc fragment of IgG, receptor, transporter, alpha 1.556
RNASE11 ribonuclease, RNase A family, 11 (non-active) 1.549
IL12RB1 interleukin 12 receptor, beta 1 1.549
REN renin 1.533
CCL11 chemokine (C-C motif) ligand 11 1.533
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.532
SEPTIN8 septin 8 1.522
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 1.518
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 1.512
MAOA monoamine oxidase A 1.507
IL15 interleukin 15 1.504
CSF3 colony stimulating factor 3 (granulocyte) 1.502
IL3 interleukin 3 1.498
IL17RC interleukin 17 receptor C 1.498
STAT1 signal transducer and activator of transcription 1, 91kDa 1.49
RNASE3 ribonuclease, RNase A family, 3 1.485
MPL MPL proto-oncogene, thrombopoietin receptor 1.476
IVL involucrin 1.469
ARL2BP ADP-ribosylation factor-like 2 binding protein 1.467
IL26 interleukin 26 1.467
IL19 interleukin 19 1.46
ADRB3 adrenoceptor beta 3 1.454
CALCB calcitonin-related polypeptide beta 1.453
TGFB1 transforming growth factor, beta 1 1.449
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 1.448
APOE apolipoprotein E 1.447
SYK spleen tyrosine kinase 1.443
CD52 CD52 molecule 1.436
LDLR low density lipoprotein receptor 1.434
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.433
RAMP1 receptor (G protein-coupled) activity modifying protein 1 1.428
DPP7 dipeptidyl-peptidase 7 1.419
STAT4 signal transducer and activator of transcription 4 1.408
IL17D interleukin 17D 1.406
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 1.402
KRT16 keratin 16, type I 1.402
APOA1 apolipoprotein A-I 1.399
KNG1 kininogen 1 1.396
IAPP islet amyloid polypeptide 1.395
HAMP hepcidin antimicrobial peptide 1.393
HCRT hypocretin (orexin) neuropeptide precursor 1.389
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.388
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.386
EDNRA endothelin receptor type A 1.386
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 1.376
CD80 CD80 molecule 1.375
STAT2 signal transducer and activator of transcription 2, 113kDa 1.373
IL17B interleukin 17B 1.368
POMC proopiomelanocortin 1.358
IL17RE interleukin 17 receptor E 1.356
NPPB natriuretic peptide B 1.35
SEPTIN6 septin 6 1.35
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.346
CD28 CD28 molecule 1.345
CXCL10 chemokine (C-X-C motif) ligand 10 1.338
STAT5B signal transducer and activator of transcription 5B 1.337
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9 1.337
PTGDR2 prostaglandin D2 receptor 2 1.336
KLKB1 kallikrein B, plasma (Fletcher factor) 1 1.334
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.33
CCL2 chemokine (C-C motif) ligand 2 1.328
APOC3 apolipoprotein C-III 1.324
OSMR oncostatin M receptor 1.322
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.319
PRL prolactin 1.318
CRLF2 cytokine receptor-like factor 2 1.31
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.309
IL18 interleukin 18 1.304
EDNRB endothelin receptor type B 1.3
CCL20 chemokine (C-C motif) ligand 20 1.296
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 1.287
AHR aryl hydrocarbon receptor 1.282
CD86 CD86 molecule 1.28
ADAMTSL5 ADAMTS-like 5 1.28
ACE2 angiotensin I converting enzyme 2 1.278
SIGLEC8 sialic acid binding Ig-like lectin 8 1.277
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.276
TNFRSF4 tumor necrosis factor receptor superfamily, member 4 1.276
IL6R interleukin 6 receptor 1.276
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 1.275
EDARADD EDAR-associated death domain 1.274
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.273
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 1.271
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 1.27
EDN1 endothelin 1 1.27
APP amyloid beta (A4) precursor protein 1.266
ICAM1 intercellular adhesion molecule 1 1.266
CCL22 chemokine (C-C motif) ligand 22 1.266
LTF lactotransferrin 1.265
VCAM1 vascular cell adhesion molecule 1 1.256
CAMP cathelicidin antimicrobial peptide 1.254
SLCO1B1 solute carrier organic anion transporter family, member 1B1 1.254
STAT5A signal transducer and activator of transcription 5A 1.252
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1 1.247
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.245
S1PR2 sphingosine-1-phosphate receptor 2 1.244
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.241
CD40LG CD40 ligand 1.235
TACR1 tachykinin receptor 1 1.233
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.231
IL13RA2 interleukin 13 receptor, alpha 2 1.228
DEFB4A defensin, beta 4A 1.226
CD27 CD27 molecule 1.225
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2 1.223
C3 complement component 3 1.222
CARD14 caspase recruitment domain family, member 14 1.221
FAP fibroblast activation protein, alpha 1.215
ADRB2 adrenoceptor beta 2, surface 1.212
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 1.211
BMX BMX non-receptor tyrosine kinase 1.209
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.2
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 1.198
PPARG peroxisome proliferator-activated receptor gamma 1.196
EPX eosinophil peroxidase 1.192
AAK1 AP2 associated kinase 1 1.191
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 1.191
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 1.19
LIPG lipase, endothelial 1.19
NPY neuropeptide Y 1.189
TRPV1 transient receptor potential cation channel, subfamily V, member 1 1.184
NEFL neurofilament, light polypeptide 1.183
NGF nerve growth factor (beta polypeptide) 1.175
CCL5 chemokine (C-C motif) ligand 5 1.174
CD40 CD40 molecule, TNF receptor superfamily member 5 1.171
IFNAR1 interferon (alpha, beta and omega) receptor 1 1.17
NLRP3 NLR family, pyrin domain containing 3 1.17
SLC47A2 solute carrier family 47 (multidrug and toxin extrusion), member 2 1.164
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.159
SPHK2 sphingosine kinase 2 1.158
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 1.156
TXK TXK tyrosine kinase 1.153
MTTP microsomal triglyceride transfer protein 1.152
FOXP3 forkhead box P3 1.151
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1.145
CD59 CD59 molecule, complement regulatory protein 1.141
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 1.138
SOST sclerostin 1.138
S100A7 S100 calcium binding protein A7 1.137
IL1R1 interleukin 1 receptor, type I 1.136
CREM cAMP responsive element modulator 1.135
F8 coagulation factor VIII, procoagulant component 1.134
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 1.134
GIPR gastric inhibitory polypeptide receptor 1.131
IFNA2 interferon, alpha 2 1.128
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.125
PDE4C phosphodiesterase 4C, cAMP-specific 1.121
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7 1.117
F9 coagulation factor IX 1.117
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3 1.111
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 1.109
EGF epidermal growth factor 1.108
HRH4 histamine receptor H4 1.108
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 1.108
IL36RN interleukin 36 receptor antagonist 1.107
LEP leptin 1.107
CFB complement factor B 1.104
IL1RAP interleukin 1 receptor accessory protein 1.103
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.099
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 1.098
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.098
EID1 EP300 interacting inhibitor of differentiation 1 1.096
SPHK1 sphingosine kinase 1 1.095
EGFR epidermal growth factor receptor 1.094
CALCRL calcitonin receptor-like 1.092
OSM oncostatin M 1.092
CCR7 chemokine (C-C motif) receptor 7 1.09
MMP9 matrix metallopeptidase 9 1.089
UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4 1.085
BCHE butyrylcholinesterase 1.085
JUN jun proto-oncogene 1.082
UGT2B11 UDP glucuronosyltransferase 2 family, polypeptide B11 1.076
PSEN2 presenilin 2 1.076
CD38 CD38 molecule 1.073
CXCL9 chemokine (C-X-C motif) ligand 9 1.073
CHIT1 chitinase 1 (chitotriosidase) 1.073
FN1 fibronectin 1 1.063
DEFB4B defensin, beta 4B 1.062
IFNA17 interferon, alpha 17 1.062
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 1.062
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.06
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.056
CCK cholecystokinin 1.054
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.052
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10 1.051
IL2RG interleukin 2 receptor, gamma 1.05
TLR7 toll-like receptor 7 1.048
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7 1.047
IFNA16 interferon, alpha 16 1.047
IFNA14 interferon, alpha 14 1.046
IFNA21 interferon, alpha 21 1.046
IFNA10 interferon, alpha 10 1.046
IFNA7 interferon, alpha 7 1.046
IFNA8 interferon, alpha 8 1.045
IFNA6 interferon, alpha 6 1.045
IFNA5 interferon, alpha 5 1.044
IFNA13 interferon, alpha 13 1.043
IFNA4 interferon, alpha 4 1.04
IL17RB interleukin 17 receptor B 1.04
DHFR2 dihydrofolate reductase 2 1.034
UGT1A5 UDP glucuronosyltransferase 1 family, polypeptide A5 1.034
SLCO1B3 solute carrier organic anion transporter family, member 1B3 1.033
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 1.032
LPL lipoprotein lipase 1.032
UGT2A3 UDP glucuronosyltransferase 2 family, polypeptide A3 1.031
UGT2A2 UDP glucuronosyltransferase 2 family, polypeptide A2 1.031
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 1.031
NPC1L1 NPC1-like 1 1.031
PDE4D phosphodiesterase 4D, cAMP-specific 1.031
PLA2G4D phospholipase A2, group IVD (cytosolic) 1.029
CD34 CD34 molecule 1.029
GAST gastrin 1.028
LTA lymphotoxin alpha 1.027
CD6 CD6 molecule 1.026
UGT2B10 UDP glucuronosyltransferase 2 family, polypeptide B10 1.025
IL17RD interleukin 17 receptor D 1.024
IGBP1 immunoglobulin (CD79A) binding protein 1 1.024
TPMT thiopurine S-methyltransferase 1.02
BCL2 B-cell CLL/lymphoma 2 1.019
CCL4 chemokine (C-C motif) ligand 4 1.019
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 1.018
BCR breakpoint cluster region 1.018
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 1.017
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 1.014
PTH parathyroid hormone 1.013
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.009
ALAS1 5'-aminolevulinate synthase 1 1.008
PDE4B phosphodiesterase 4B, cAMP-specific 1.005
DRD2 dopamine receptor D2 1.002
ACHE acetylcholinesterase (Yt blood group) 1.001