| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/5311309 |
| Similar Terms | |
| Downloads & Tools |
199 proteins with high or low expression in Nateglinide relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GREB1 | growth regulation by estrogen in breast cancer 1 | 3.21 |
| PIP | prolactin-induced protein | 1.44 |
| DNAH6 | dynein, axonemal, heavy chain 6 | 1.34 |
| TRIM29 | tripartite motif containing 29 | 1.2 |
| FBXW8 | F-box and WD repeat domain containing 8 | 1.07 |
| C12ORF66 | chromosome 12 open reading frame 66 | 1.04 |
| KMT2B | lysine (K)-specific methyltransferase 2B | 0.95 |
| RGN | regucalcin | 0.92 |
| RAD52 | RAD52 homolog (S. cerevisiae) | 0.89 |
| MYH16 | myosin, heavy chain 16 pseudogene | 0.87 |
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 | 0.86 |
| SRSF8 | serine/arginine-rich splicing factor 8 | 0.82 |
| CNPY2 | canopy FGF signaling regulator 2 | 0.81 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.75 |
| WDR20 | WD repeat domain 20 | 0.74 |
| ZBED9 | zinc finger, BED-type containing 9 | 0.71 |
| ESAM | endothelial cell adhesion molecule | 0.71 |
| HAS3 | hyaluronan synthase 3 | 0.71 |
| SPPL2A | signal peptide peptidase like 2A | 0.7 |
| ST5 | suppression of tumorigenicity 5 | 0.7 |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.68 |
| PNPO | pyridoxamine 5'-phosphate oxidase | 0.57 |
| PRKD3 | protein kinase D3 | 0.55 |
| ONECUT3 | one cut homeobox 3 | 0.55 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 0.53 |
| MT-ATP6 | ATP synthase F0 subunit 6 | 0.53 |
| CD81 | CD81 molecule | 0.53 |
| NIPSNAP1 | nipsnap homolog 1 (C. elegans) | 0.52 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | 0.52 |
| SNRPD1 | small nuclear ribonucleoprotein D1 polypeptide 16kDa | 0.52 |
| SUMO1 | small ubiquitin-like modifier 1 | 0.51 |
| EXOSC2 | exosome component 2 | 0.5 |
| KLHL5 | kelch-like family member 5 | 0.5 |
| NPHP3 | nephronophthisis 3 (adolescent) | 0.49 |
| SPCS1 | signal peptidase complex subunit 1 homolog (S. cerevisiae) | 0.49 |
| TFCP2 | transcription factor CP2 | 0.49 |
| ZNF263 | zinc finger protein 263 | 0.48 |
| PGPEP1 | pyroglutamyl-peptidase I | 0.47 |
| NFYA | nuclear transcription factor Y, alpha | 0.47 |
| PAAF1 | proteasomal ATPase-associated factor 1 | 0.46 |
| FKBP2 | FK506 binding protein 2, 13kDa | 0.45 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.45 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | 0.41 |
| ROGDI | rogdi homolog (Drosophila) | 0.41 |
| IFFO2 | intermediate filament family orphan 2 | 0.4 |
| TSLIG3C | tRNA splicing ligase complex subunit 3C | 0.4 |
| CEPT1 | choline/ethanolamine phosphotransferase 1 | 0.38 |
| PRDM10 | PR domain containing 10 | 0.38 |
| B2M | beta-2-microglobulin | 0.38 |
| ZNF320 | zinc finger protein 320 | 0.37 |
| GLI2 | GLI family zinc finger 2 | 0.36 |
| FAM102A | family with sequence similarity 102, member A | 0.36 |
| USP11 | ubiquitin specific peptidase 11 | 0.36 |
| MGLL | monoglyceride lipase | 0.36 |
| TMPO | thymopoietin | 0.35 |
| S100A4 | S100 calcium binding protein A4 | 0.35 |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa | 0.35 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.35 |
| DHDDS | dehydrodolichyl diphosphate synthase | 0.35 |
| NOP10 | NOP10 ribonucleoprotein | 0.35 |
| ATPAF2 | ATP synthase mitochondrial F1 complex assembly factor 2 | 0.34 |
| C20ORF27 | chromosome 20 open reading frame 27 | 0.34 |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma | 0.34 |
| SELENOI | selenoprotein I | 0.34 |
| RPL30 | ribosomal protein L30 | 0.34 |
| ELOC | elongin C | 0.34 |
| WNT10B | wingless-type MMTV integration site family, member 10B | 0.33 |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H | 0.33 |
| RNF2 | ring finger protein 2 | 0.33 |
| BSG | basigin (Ok blood group) | 0.33 |
| YBX3 | Y box binding protein 3 | 0.33 |
| DCHS1 | dachsous cadherin-related 1 | 0.33 |
| E2F8 | E2F transcription factor 8 | 0.32 |
| PPP3CB | protein phosphatase 3, catalytic subunit, beta isozyme | 0.32 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.32 |
| KCTD5 | potassium channel tetramerization domain containing 5 | 0.32 |
| ETAA1 | Ewing tumor-associated antigen 1 | 0.32 |
| ZNF91 | zinc finger protein 91 | 0.32 |
| MTCH2 | mitochondrial carrier 2 | 0.31 |
| FKBP4 | FK506 binding protein 4, 59kDa | 0.31 |
| COPS7A | COP9 signalosome subunit 7A | 0.31 |
| XDH | xanthine dehydrogenase | 0.31 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.31 |
| ZBTB1 | zinc finger and BTB domain containing 1 | 0.31 |
| PSPH | phosphoserine phosphatase | 0.31 |
| SKIL | SKI-like proto-oncogene | 0.3 |
| MICOS10 | mitochondrial contact site and cristae organizing system subunit 10 | 0.3 |
| RPGR | retinitis pigmentosa GTPase regulator | 0.29 |
| MAIP1 | matrix AAA peptidase interacting protein 1 | 0.29 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 0.29 |
| EIF4E2 | eukaryotic translation initiation factor 4E family member 2 | 0.29 |
| STX12 | syntaxin 12 | 0.29 |
| SLC41A1 | solute carrier family 41 (magnesium transporter), member 1 | 0.29 |
| MTIF3 | mitochondrial translational initiation factor 3 | 0.29 |
| LIN7A | lin-7 homolog A (C. elegans) | 0.29 |
| RPA2 | replication protein A2, 32kDa | 0.28 |
| WDR6 | WD repeat domain 6 | 0.28 |
| SLC25A30 | solute carrier family 25, member 30 | 0.28 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 0.28 |
| BRCC3 | BRCA1/BRCA2-containing complex, subunit 3 | 0.27 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C | -1.03 |
| HELQ | helicase, POLQ-like | -0.95 |
| TAPT1 | transmembrane anterior posterior transformation 1 | -0.79 |
| MEGF8 | multiple EGF-like-domains 8 | -0.69 |
| LMLN | leishmanolysin-like (metallopeptidase M8 family) | -0.69 |
| ZFP30 | ZFP30 zinc finger protein | -0.69 |
| ZNF628 | zinc finger protein 628 | -0.65 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.62 |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase | -0.61 |
| NFYB | nuclear transcription factor Y, beta | -0.59 |
| COA4 | cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) | -0.58 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.57 |
| BTG3 | BTG family, member 3 | -0.56 |
| METTL4 | methyltransferase like 4 | -0.56 |
| POMP | proteasome maturation protein | -0.55 |
| TBC1D32 | TBC1 domain family, member 32 | -0.53 |
| TRAF3IP2 | TRAF3 interacting protein 2 | -0.52 |
| NPDC1 | neural proliferation, differentiation and control, 1 | -0.51 |
| DYNC2LI1 | dynein, cytoplasmic 2, light intermediate chain 1 | -0.51 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | -0.5 |
| ZNF408 | zinc finger protein 408 | -0.5 |
| XTBD1 | XRN2 binding domain containing 1 | -0.49 |
| JAK2 | Janus kinase 2 | -0.48 |
| CLIC3 | chloride intracellular channel 3 | -0.48 |
| YAF2 | YY1 associated factor 2 | -0.48 |
| ZXDB | zinc finger, X-linked, duplicated B | -0.47 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) | -0.47 |
| ANTXR2 | anthrax toxin receptor 2 | -0.46 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.46 |
| BHMT | betaine--homocysteine S-methyltransferase | -0.45 |
| MED10 | mediator complex subunit 10 | -0.44 |
| GNB5 | guanine nucleotide binding protein (G protein), beta 5 | -0.44 |
| PXYLP1 | 2-phosphoxylose phosphatase 1 | -0.43 |
| ZNF12 | zinc finger protein 12 | -0.43 |
| KSR2 | kinase suppressor of ras 2 | -0.43 |
| TSTD1 | thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 | -0.42 |
| S100A14 | S100 calcium binding protein A14 | -0.42 |
| KIAA1109 | KIAA1109 | -0.42 |
| RAB11FIP4 | RAB11 family interacting protein 4 (class II) | -0.41 |
| TBC1D16 | TBC1 domain family, member 16 | -0.41 |
| PLEC | plectin | -0.41 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.4 |
| SPIDR | scaffolding protein involved in DNA repair | -0.4 |
| WDR25 | WD repeat domain 25 | -0.4 |
| KLHL20 | kelch-like family member 20 | -0.4 |
| CMC4 | C-x(9)-C motif containing 4 | -0.39 |
| TOX2 | TOX high mobility group box family member 2 | -0.39 |
| LYPLA2 | lysophospholipase II | -0.39 |
| C20ORF194 | chromosome 20 open reading frame 194 | -0.39 |
| USP27X | ubiquitin specific peptidase 27, X-linked | -0.38 |
| ANKS6 | ankyrin repeat and sterile alpha motif domain containing 6 | -0.38 |
| C2ORF76 | chromosome 2 open reading frame 76 | -0.38 |
| CCDC9B | coiled-coil domain containing 9B | -0.38 |
| ZBTB4 | zinc finger and BTB domain containing 4 | -0.37 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.37 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 | -0.36 |
| ANKRD13B | ankyrin repeat domain 13B | -0.36 |
| CYB5A | cytochrome b5 type A (microsomal) | -0.36 |
| FKRP | fukutin related protein | -0.36 |
| TMEM102 | transmembrane protein 102 | -0.36 |
| TRAF5 | TNF receptor-associated factor 5 | -0.36 |
| KIF26A | kinesin family member 26A | -0.36 |
| ATP6V1F | ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F | -0.35 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.35 |
| NOTCH3 | notch 3 | -0.35 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -0.35 |
| GALT | galactose-1-phosphate uridylyltransferase | -0.35 |
| KIF1B | kinesin family member 1B | -0.34 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | -0.34 |
| RAB27B | RAB27B, member RAS oncogene family | -0.34 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | -0.34 |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 | -0.34 |
| ZBED8L | ZBED8 like | -0.34 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.34 |
| ERVMER34-1 | endogenous retrovirus group MER34, member 1 | -0.34 |
| TMEM147 | transmembrane protein 147 | -0.33 |
| ZNF16 | zinc finger protein 16 | -0.33 |
| CCNF | cyclin F | -0.33 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.33 |
| SUPT7L | suppressor of Ty 7 (S. cerevisiae)-like | -0.33 |
| MID2 | midline 2 | -0.33 |
| DOCK11 | dedicator of cytokinesis 11 | -0.32 |
| RHBDD1 | rhomboid domain containing 1 | -0.32 |
| COMMD8 | COMM domain containing 8 | -0.32 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.32 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.32 |
| METTL25 | methyltransferase like 25 | -0.32 |
| ZNF319 | zinc finger protein 319 | -0.32 |
| AGPAT2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 | -0.32 |
| ADIRF | adipogenesis regulatory factor | -0.32 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | -0.32 |
| BAG4 | BCL2-associated athanogene 4 | -0.32 |
| FAM104A | family with sequence similarity 104, member A | -0.32 |
| DEDD | death effector domain containing | -0.31 |
| RGPD2 | RANBP2-like and GRIP domain containing 2 | -0.31 |
| CHKB | choline kinase beta | -0.31 |
| BAHD1 | bromo adjacent homology domain containing 1 | -0.31 |
| TUSC2 | tumor suppressor candidate 2 | -0.31 |
| PRXL2C | peroxiredoxin like 2C | -0.31 |
