Necrotizing Enterocolitis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0520459
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Genes

100 genes associated with the disease Necrotizing Enterocolitis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
ACTA1 actin, alpha 1, skeletal muscle
ADCY4 adenylate cyclase 4
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase)
ALB albumin
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ARRB2 arrestin, beta 2
ASL argininosuccinate lyase
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BANP BTG3 associated nuclear protein
CAV1 caveolin 1, caveolae protein, 22kDa
CCR9 chemokine (C-C motif) receptor 9
CD14 CD14 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CLDN2 claudin 2
COX2
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CRHR1 corticotropin releasing hormone receptor 1
CRHR2 corticotropin releasing hormone receptor 2
CRP C-reactive protein, pentraxin-related
CRYL1 crystallin, lambda 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DEFA6 defensin, alpha 6, Paneth cell-specific
DEFB103A defensin, beta 103A
DEFB103B defensin, beta 103B
DEFB4A defensin, beta 4A
DEFB4B defensin, beta 4B
EGF epidermal growth factor
EGFR epidermal growth factor receptor
ENO1 enolase 1, (alpha)
EPO erythropoietin
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FOXA1 forkhead box A1
GLRX glutaredoxin (thioltransferase)
HBEGF heparin-binding EGF-like growth factor
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HMGB1 high mobility group box 1
HSPA9 heat shock 70kDa protein 9 (mortalin)
IGF1 insulin-like growth factor 1 (somatomedin C)
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL10 interleukin 10
IL10RB interleukin 10 receptor, beta
IL11 interleukin 11
IL17A interleukin 17A
IL18 interleukin 18
IL1B interleukin 1, beta
IL22 interleukin 22
IL23A interleukin 23, alpha subunit p19
IL23R interleukin 23 receptor
IL33 interleukin 33
IL4 interleukin 4
IL4R interleukin 4 receptor
IL6 interleukin 6
IRF5 interferon regulatory factor 5
LGALS2 lectin, galactoside-binding, soluble, 2
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LTF lactotransferrin
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK8 mitogen-activated protein kinase 8
MBL2 mannose-binding lectin (protein C) 2, soluble
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MMP3 matrix metallopeptidase 3
MUC2 mucin 2, oligomeric mucus/gel-forming
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
NOD2 nucleotide-binding oligomerization domain containing 2
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NR1I2 nuclear receptor subfamily 1, group I, member 2
OAT ornithine aminotransferase
PARK7 parkinson protein 7
PARP1 poly (ADP-ribose) polymerase 1
PPARG peroxisome proliferator-activated receptor gamma
PTAFR platelet-activating factor receptor
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
REN renin
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SMAD7 SMAD family member 7
SNAI3 snail family zinc finger 3
SOD2 superoxide dismutase 2, mitochondrial
SORD sorbitol dehydrogenase
TGFB2 transforming growth factor, beta 2
THBD thrombomodulin
TJP1 tight junction protein 1
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR6 toll-like receptor 6
TLR7 toll-like receptor 7
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TOLLIP toll interacting protein
TUBB tubulin, beta class I
VEGFA vascular endothelial growth factor A
VIP vasoactive intestinal peptide