Neddylation Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-8951664
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Genes

231 proteins participating in the Neddylation pathway from the Reactome Pathways 2024 dataset.

Symbol Name
ADRM1 adhesion regulating molecule 1
AMER1 APC membrane recruitment protein 1
ANKRD9 ankyrin repeat domain 9
ASB1 ankyrin repeat and SOCS box containing 1
ASB10 ankyrin repeat and SOCS box containing 10
ASB11 ankyrin repeat and SOCS box containing 11, E3 ubiquitin protein ligase
ASB12 ankyrin repeat and SOCS box containing 12
ASB13 ankyrin repeat and SOCS box containing 13
ASB14 ankyrin repeat and SOCS box containing 14
ASB15 ankyrin repeat and SOCS box containing 15
ASB16 ankyrin repeat and SOCS box containing 16
ASB17 ankyrin repeat and SOCS box containing 17
ASB18 ankyrin repeat and SOCS box containing 18
ASB2 ankyrin repeat and SOCS box containing 2
ASB3 ankyrin repeat and SOCS box containing 3
ASB4 ankyrin repeat and SOCS box containing 4
ASB5 ankyrin repeat and SOCS box containing 5
ASB6 ankyrin repeat and SOCS box containing 6
ASB7 ankyrin repeat and SOCS box containing 7
ASB8 ankyrin repeat and SOCS box containing 8
ASB9 ankyrin repeat and SOCS box containing 9
BIRC5 baculoviral IAP repeat containing 5
BRCA1 breast cancer 1, early onset
BTBD1 BTB (POZ) domain containing 1
BTBD6 BTB (POZ) domain containing 6
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CAND1 cullin-associated and neddylation-dissociated 1
CCDC22 coiled-coil domain containing 22
CCDC8 coiled-coil domain containing 8
CCNF cyclin F
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CISH cytokine inducible SH2-containing protein
COMMD1 copper metabolism (Murr1) domain containing 1
COMMD10 COMM domain containing 10
COMMD2 COMM domain containing 2
COMMD3 COMM domain containing 3
COMMD4 COMM domain containing 4
COMMD5 COMM domain containing 5
COMMD6 COMM domain containing 6
COMMD7 COMM domain containing 7
COMMD8 COMM domain containing 8
COMMD9 COMM domain containing 9
COP1 COP1 E3 ubiquitin ligase
COPS2 COP9 signalosome subunit 2
COPS3 COP9 signalosome subunit 3
COPS4 COP9 signalosome subunit 4
COPS5 COP9 signalosome subunit 5
COPS6 COP9 signalosome subunit 6
COPS7A COP9 signalosome subunit 7A
COPS7B COP9 signalosome subunit 7B
COPS8 COP9 signalosome subunit 8
CUL1 cullin 1
CUL2 cullin 2
CUL3 cullin 3
CUL4A cullin 4A
CUL4B cullin 4B
CUL5 cullin 5
CUL7 cullin 7
CUL9 cullin 9
DCAF10 DDB1 and CUL4 associated factor 10
DCAF11 DDB1 and CUL4 associated factor 11
DCAF13 DDB1 and CUL4 associated factor 13
DCAF16 DDB1 and CUL4 associated factor 16
DCAF17 DDB1 and CUL4 associated factor 17
DCAF4 DDB1 and CUL4 associated factor 4
DCAF5 DDB1 and CUL4 associated factor 5
DCAF6 DDB1 and CUL4 associated factor 6
DCAF7 DDB1 and CUL4 associated factor 7
DCAF8 DDB1 and CUL4 associated factor 8
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DCUN1D3 DCN1, defective in cullin neddylation 1, domain containing 3
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4
DCUN1D5 DCN1, defective in cullin neddylation 1, domain containing 5
DDA1 DET1 and DDB1 associated 1
DDB1 damage-specific DNA binding protein 1, 127kDa
DDB2 damage-specific DNA binding protein 2, 48kDa
DPP3 dipeptidyl-peptidase 3
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
ELOB elongin B
ELOC elongin C
ERCC8 excision repair cross-complementation group 8
FBXL12 F-box and leucine-rich repeat protein 12
FBXL13 F-box and leucine-rich repeat protein 13
FBXL14 F-box and leucine-rich repeat protein 14
FBXL15 F-box and leucine-rich repeat protein 15
FBXL16 F-box and leucine-rich repeat protein 16
FBXL18 F-box and leucine-rich repeat protein 18
FBXL19 F-box and leucine-rich repeat protein 19
FBXL20 F-box and leucine-rich repeat protein 20
FBXL22 F-box and leucine-rich repeat protein 22
FBXL3 F-box and leucine-rich repeat protein 3
FBXL4 F-box and leucine-rich repeat protein 4
FBXL5 F-box and leucine-rich repeat protein 5
FBXL7 F-box and leucine-rich repeat protein 7
FBXL8 F-box and leucine-rich repeat protein 8
FBXO10 F-box protein 10
FBXO11 F-box protein 11
FBXO15 F-box protein 15
FBXO17 F-box protein 17
FBXO2 F-box protein 2
FBXO21 F-box protein 21
FBXO22 F-box protein 22
FBXO27 F-box protein 27
FBXO30 F-box protein 30
FBXO31 F-box protein 31
FBXO32 F-box protein 32
FBXO4 F-box protein 4
FBXO40 F-box protein 40
FBXO41 F-box protein 41
FBXO44 F-box protein 44
FBXO6 F-box protein 6
FBXO7 F-box protein 7
FBXO9 F-box protein 9
FBXW10 F-box and WD repeat domain containing 10
FBXW11 F-box and WD repeat domain containing 11
FBXW12 F-box and WD repeat domain containing 12
FBXW2 F-box and WD repeat domain containing 2
FBXW4 F-box and WD repeat domain containing 4
FBXW5 F-box and WD repeat domain containing 5
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FBXW8 F-box and WD repeat domain containing 8
FBXW9 F-box and WD repeat domain containing 9
FEM1A fem-1 homolog a (C. elegans)
FEM1B fem-1 homolog b (C. elegans)
FEM1C fem-1 homolog c (C. elegans)
GAN gigaxonin
GPS1 G protein pathway suppressor 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIF3A hypoxia inducible factor 3, alpha subunit
KBTBD13 kelch repeat and BTB (POZ) domain containing 13
KBTBD6 kelch repeat and BTB (POZ) domain containing 6
KBTBD7 kelch repeat and BTB (POZ) domain containing 7
KBTBD8 kelch repeat and BTB (POZ) domain containing 8
KCTD6 potassium channel tetramerization domain containing 6
KCTD7 potassium channel tetramerization domain containing 7
KEAP1 kelch-like ECH-associated protein 1
KLHL11 kelch-like family member 11
KLHL13 kelch-like family member 13
KLHL2 kelch-like family member 2
KLHL20 kelch-like family member 20
KLHL21 kelch-like family member 21
KLHL22 kelch-like family member 22
KLHL25 kelch-like family member 25
KLHL3 kelch-like family member 3
KLHL41 kelch-like family member 41
KLHL42 kelch-like family member 42
KLHL5 kelch-like family member 5
KLHL9 kelch-like family member 9
LMO7 LIM domain 7
LRR1 leucine rich repeat protein 1
LRRC41 leucine rich repeat containing 41
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NAE1 NEDD8 activating enzyme E1 subunit 1
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NEURL2 neuralized E3 ubiquitin protein ligase 2
NFE2L2 nuclear factor, erythroid 2-like 2
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae)
NUB1 negative regulator of ubiquitin-like proteins 1
OBSL1 obscurin-like 1
PALB2 partner and localizer of BRCA2
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PUM2 pumilio RNA-binding family member 2
RBBP5 retinoblastoma binding protein 5
RBBP7 retinoblastoma binding protein 7
RBX1 ring-box 1, E3 ubiquitin protein ligase
RNF7 ring finger protein 7
RPS27A ribosomal protein S27a
SEM1 SEM1 26S proteasome subunit
SENP8 SUMO/sentrin specific peptidase family member 8
SKP1 S-phase kinase-associated protein 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SOCS2 suppressor of cytokine signaling 2
SOCS3 suppressor of cytokine signaling 3
SOCS5 suppressor of cytokine signaling 5
SOCS6 suppressor of cytokine signaling 6
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SPSB2 splA/ryanodine receptor domain and SOCS box containing 2
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
SPSB4 splA/ryanodine receptor domain and SOCS box containing 4
SQSTM1 sequestosome 1
TULP4 tubby like protein 4
UBA3 ubiquitin-like modifier activating enzyme 3
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBD ubiquitin D
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2D2 ubiquitin-conjugating enzyme E2D 2
UBE2D3 ubiquitin-conjugating enzyme E2D 3
UBE2F ubiquitin-conjugating enzyme E2F (putative)
UBE2M ubiquitin-conjugating enzyme E2M
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
UFD1 ubiquitin recognition factor in ER associated degradation 1
VCP valosin containing protein
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WDR5 WD repeat domain 5
WDTC1 WD and tetratricopeptide repeats 1
WIPF1 WAS/WASL interacting protein family, member 1
WSB1 WD repeat and SOCS box containing 1
WSB2 WD repeat and SOCS box containing 2
ZBTB16 zinc finger and BTB domain containing 16