Negative regulators of RIG-I/MDA5 signaling Gene Set

Dataset Reactome Pathways 2014
Category structural or functional annotations
Type pathway
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-936440
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Genes

33 proteins participating in the Negative regulators of RIG-I/MDA5 signaling pathway from the Reactome Pathways dataset.

Symbol Name
ATG12 autophagy related 12
ATG5 autophagy related 5
CYLD cylindromatosis (turban tumor syndrome)
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
IFIH1 interferon induced with helicase C domain 1
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IRF3 interferon regulatory factor 3
ISG15 ISG15 ubiquitin-like modifier
ITCH itchy E3 ubiquitin protein ligase
MAVS mitochondrial antiviral signaling protein
NLRC5 NLR family, CARD domain containing 5
NLRX1 NLR family member X1
OTUD5 OTU deubiquitinase 5
PCBP2 poly(rC) binding protein 2
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF135 ring finger protein 135
RPS27A ribosomal protein S27a
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TBK1 TANK-binding kinase 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRAF3 TNF receptor-associated factor 3
TRIM25 tripartite motif containing 25
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBA7 ubiquitin-like modifier activating enzyme 7
UBB ubiquitin B
UBC ubiquitin C
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2D2 ubiquitin-conjugating enzyme E2D 2
UBE2D3 ubiquitin-conjugating enzyme E2D 3
UBE2K ubiquitin-conjugating enzyme E2K
UBE2L6 ubiquitin-conjugating enzyme E2L 6