Nemaline Myopathy_Gastrocnemius Muscle_GSE3384 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE3384
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Genes

600 genes differentially expressed during Nemaline Myopathy_Gastrocnemius Muscle_GSE3384 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) 3.74765
LIMS1 LIM and senescent cell antigen-like domains 1 3.6552
RAB11FIP5 RAB11 family interacting protein 5 (class I) 3.56179
BAG3 BCL2-associated athanogene 3 3.51407
PQLC1 PQ loop repeat containing 1 3.39818
ATXN2 ataxin 2 3.24865
PDCD7 programmed cell death 7 3.18928
MSL1 male-specific lethal 1 homolog (Drosophila) 3.18741
PRDX2 peroxiredoxin 2 3.15318
AKIRIN2 akirin 2 2.99679
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 2.93814
RCAN1 regulator of calcineurin 1 2.93489
MRPL43 mitochondrial ribosomal protein L43 2.88027
NKIRAS2 NFKB inhibitor interacting Ras-like 2 2.8177
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 2.80092
DSCR3 Down syndrome critical region 3 2.76247
POLR2G polymerase (RNA) II (DNA directed) polypeptide G 2.76184
PRRC1 proline-rich coiled-coil 1 2.7378
PDLIM1 PDZ and LIM domain 1 2.71684
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 2.70499
IGBP1 immunoglobulin (CD79A) binding protein 1 2.67295
HSPH1 heat shock 105kDa/110kDa protein 1 2.67085
DIAPH1 diaphanous-related formin 1 2.63283
CDC42SE1 CDC42 small effector 1 2.61522
MAEA macrophage erythroblast attacher 2.61286
STX7 syntaxin 7 2.61106
PTDSS1 phosphatidylserine synthase 1 2.58868
HSPA1L heat shock 70kDa protein 1-like 2.56846
XIRP1 xin actin binding repeat containing 1 2.56523
PUF60 poly-U binding splicing factor 60KDa 2.52442
SDHAF1 succinate dehydrogenase complex assembly factor 1 2.5011
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 2.49627
SRPK3 SRSF protein kinase 3 2.49334
MYH14 myosin, heavy chain 14, non-muscle 2.4611
LONP1 lon peptidase 1, mitochondrial 2.44713
MRPL27 mitochondrial ribosomal protein L27 2.44371
NRAP nebulin-related anchoring protein 2.44052
WFS1 Wolfram syndrome 1 (wolframin) 2.43875
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like 2.43637
CDC5L cell division cycle 5-like 2.42747
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) 2.41814
UCK2 uridine-cytidine kinase 2 2.41574
WDR1 WD repeat domain 1 2.39812
MRPS18B mitochondrial ribosomal protein S18B 2.39365
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 2.36731
PARD3 par-3 family cell polarity regulator 2.36326
ODC1 ornithine decarboxylase 1 2.35366
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 2.35191
SDR42E1 short chain dehydrogenase/reductase family 42E, member 1 2.34555
ATG13 autophagy related 13 2.33539
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25 2.31713
MAPT microtubule-associated protein tau 2.30054
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 2.29845
DGUOK deoxyguanosine kinase 2.28952
THUMPD1 THUMP domain containing 1 2.2873
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 2.27857
PDE8A phosphodiesterase 8A 2.26611
ARPP19 cAMP-regulated phosphoprotein, 19kDa 2.2592
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 2.24895
COL4A1 collagen, type IV, alpha 1 2.23268
DDR1 discoidin domain receptor tyrosine kinase 1 2.22708
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2.22396
SNAP47 synaptosomal-associated protein, 47kDa 2.21941
USP3 ubiquitin specific peptidase 3 2.21541
SOS1 son of sevenless homolog 1 (Drosophila) 2.21081
CAV3 caveolin 3 2.20896
SMAD1 SMAD family member 1 2.18633
GTF2A1 general transcription factor IIA, 1, 19/37kDa 2.14037
PRPF19 pre-mRNA processing factor 19 2.13342
COL4A2 collagen, type IV, alpha 2 2.13158
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 2.11712
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 2.11416
ADGRG1 adhesion G protein-coupled receptor G1 2.1025
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) 2.10205
DBNDD2 dysbindin (dystrobrevin binding protein 1) domain containing 2 2.10179
TMEM222 transmembrane protein 222 2.10171
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 2.09375
DOHH deoxyhypusine hydroxylase/monooxygenase 2.08571
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa 2.07834
MTMR9 myotubularin related protein 9 2.07039
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 2.06838
LMNA lamin A/C 2.06723
LMO7 LIM domain 7 2.06397
PLA2G12A phospholipase A2, group XIIA 2.05266
ZBTB20 zinc finger and BTB domain containing 20 2.04892
KIF22 kinesin family member 22 2.04379
TEX30 testis expressed 30 2.0367
LRRC4B leucine rich repeat containing 4B 2.03515
DDB1 damage-specific DNA binding protein 1, 127kDa 2.02613
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 2.02447
SKP1 S-phase kinase-associated protein 1 2.01205
MRPL18 mitochondrial ribosomal protein L18 2.00118
BOLA3 bolA family member 3 1.99832
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa 1.9972
ZMAT3 zinc finger, matrin-type 3 1.9839
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 1.97815
ANKRD17 ankyrin repeat domain 17 1.97175
MRPL28 mitochondrial ribosomal protein L28 1.9671
TRAK1 trafficking protein, kinesin binding 1 1.95255
TRNT1 tRNA nucleotidyl transferase, CCA-adding, 1 1.94984
TRAF3 TNF receptor-associated factor 3 1.94773
HSPB8 heat shock 22kDa protein 8 1.9472
GTPBP1 GTP binding protein 1 1.94407
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 1.94033
DUSP12 dual specificity phosphatase 12 1.93408
INCA1 inhibitor of CDK, cyclin A1 interacting protein 1 1.93351
SVIL supervillin 1.93277
DHRS7 dehydrogenase/reductase (SDR family) member 7 1.92727
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 1.92526
HSPA9 heat shock 70kDa protein 9 (mortalin) 1.92505
DCTN1 dynactin 1 1.92328
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 1.91462
TBC1D23 TBC1 domain family, member 23 1.90988
UNC119B unc-119 homolog B (C. elegans) 1.9064
NFIB nuclear factor I/B 1.89558
ZNF292 zinc finger protein 292 1.89406
ZNFX1 zinc finger, NFX1-type containing 1 1.88246
MAGOH mago-nashi homolog, proliferation-associated (Drosophila) 1.87475
FAM151A family with sequence similarity 151, member A 1.87128
TSNAX translin-associated factor X 1.87127
LEMD2 LEM domain containing 2 1.86893
GABARAP GABA(A) receptor-associated protein 1.86848
ZNF703 zinc finger protein 703 1.85841
AGTRAP angiotensin II receptor-associated protein 1.85725
WWTR1 WW domain containing transcription regulator 1 1.84964
PREPL prolyl endopeptidase-like 1.84592
COPS4 COP9 signalosome subunit 4 1.84433
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 1.8437
ZSWIM7 zinc finger, SWIM-type containing 7 1.84208
HAT1 histone acetyltransferase 1 1.84153
EGLN2 egl-9 family hypoxia-inducible factor 2 1.83928
SLMAP sarcolemma associated protein 1.83633
PIAS3 protein inhibitor of activated STAT, 3 1.8349
FGF6 fibroblast growth factor 6 1.83382
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 1.83199
PHF23 PHD finger protein 23 1.82868
TNPO2 transportin 2 1.82575
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 1.82454
WSB2 WD repeat and SOCS box containing 2 1.82391
PNPLA2 patatin-like phospholipase domain containing 2 1.82201
ERH enhancer of rudimentary homolog (Drosophila) 1.81777
APP amyloid beta (A4) precursor protein 1.80926
MRPS12 mitochondrial ribosomal protein S12 1.79952
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 1.79052
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) 1.78804
ABLIM1 actin binding LIM protein 1 1.7819
HIST1H3C histone cluster 1, H3c 1.77767
SWI5 SWI5 recombination repair homolog (yeast) 1.77171
NIT1 nitrilase 1 1.77002
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 1.76929
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 1.76224
ZC3H12C zinc finger CCCH-type containing 12C 1.75949
H2AFV H2A histone family, member V 1.75641
RAB31 RAB31, member RAS oncogene family 1.7512
MAPK12 mitogen-activated protein kinase 12 1.75
TMED7 transmembrane emp24 protein transport domain containing 7 1.74913
LPP LIM domain containing preferred translocation partner in lipoma 1.74798
VPS26B vacuolar protein sorting 26 homolog B (S. pombe) 1.74722
IGF2 insulin-like growth factor 2 1.74643
COLGALT1 collagen beta(1-O)galactosyltransferase 1 1.74232
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 1.74012
DENND5A DENN/MADD domain containing 5A 1.7385
SQSTM1 sequestosome 1 1.72863
WBP1 WW domain binding protein 1 1.72218
TMEM159 transmembrane protein 159 1.7216
CD160 CD160 molecule 1.71343
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 1.7115
PTPN1 protein tyrosine phosphatase, non-receptor type 1 1.70981
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 1.70869
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 1.70781
TUBA1B tubulin, alpha 1b 1.70003
RASA3 RAS p21 protein activator 3 1.699
SLC35E1 solute carrier family 35, member E1 1.69851
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 1.69792
JOSD2 Josephin domain containing 2 1.69438
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 1.68924
PLRG1 pleiotropic regulator 1 1.68877
CTPS2 CTP synthase 2 1.68687
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa 1.68609
NCKAP1 NCK-associated protein 1 1.68345
EXOC8 exocyst complex component 8 1.68309
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa 1.68124
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa 1.67987
PLEKHO1 pleckstrin homology domain containing, family O member 1 1.67468
RCSD1 RCSD domain containing 1 1.67313
RNF181 ring finger protein 181 1.67299
TCF12 transcription factor 12 1.66753
NTPCR nucleoside-triphosphatase, cancer-related 1.6665
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial 1.66556
ADIPOR2 adiponectin receptor 2 1.6644
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 1.6635
ZP2 zona pellucida glycoprotein 2 (sperm receptor) 1.66252
RIT1 Ras-like without CAAX 1 1.66109
UBXN1 UBX domain protein 1 1.65867
VAC14 Vac14 homolog (S. cerevisiae) 1.65698
MEF2D myocyte enhancer factor 2D 1.65624
TRAPPC2L trafficking protein particle complex 2-like 1.65554
TSEN34 TSEN34 tRNA splicing endonuclease subunit 1.65264
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.65084
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide 1.64797
SAMM50 SAMM50 sorting and assembly machinery component 1.64675
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 1.64648
SMNDC1 survival motor neuron domain containing 1 1.64035
PDCD2L programmed cell death 2-like 1.63705
LAS1L LAS1-like (S. cerevisiae) 1.6368
INPPL1 inositol polyphosphate phosphatase-like 1 1.63518
LMF1 lipase maturation factor 1 1.62893
CYB5R4 cytochrome b5 reductase 4 1.62836
CUL2 cullin 2 1.62648
TMEM131 transmembrane protein 131 1.62594
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G 1.62456
SSPN sarcospan 1.62442
MRPL20 mitochondrial ribosomal protein L20 1.62164
NCOR1 nuclear receptor corepressor 1 1.62116
BAZ1B bromodomain adjacent to zinc finger domain, 1B 1.62024
APC adenomatous polyposis coli 1.61948
SAE1 SUMO1 activating enzyme subunit 1 1.61639
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 1.61457
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 1.61257
METTL1 methyltransferase like 1 1.61227
RB1 retinoblastoma 1 1.61193
SFR1 SWI5-dependent recombination repair 1 1.60959
RALBP1 ralA binding protein 1 1.60804
MDN1 MDN1, midasin homolog (yeast) 1.60792
ATXN10 ataxin 10 1.60573
CPNE3 copine III 1.60149
AMOT angiomotin 1.59975
SPPL3 signal peptide peptidase like 3 1.59595
OXT oxytocin/neurophysin I prepropeptide 1.59293
UBFD1 ubiquitin family domain containing 1 1.5929
LENG9 leukocyte receptor cluster (LRC) member 9 1.59081
CECR5 cat eye syndrome chromosome region, candidate 5 1.59013
HIGD2A HIG1 hypoxia inducible domain family, member 2A 1.58539
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 1.57818
ACP1 acid phosphatase 1, soluble 1.57278
NPEPL1 aminopeptidase-like 1 1.57252
CUL4A cullin 4A 1.57175
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) 1.56586
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 1.56572
TP53 tumor protein p53 1.56473
FTH1 ferritin, heavy polypeptide 1 1.56057
MTA2 metastasis associated 1 family, member 2 1.55982
PCBP2 poly(rC) binding protein 2 1.55965
NME1 NME/NM23 nucleoside diphosphate kinase 1 1.55507
CUL1 cullin 1 1.55289
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 1.55281
AAMP angio-associated, migratory cell protein 1.55121
NCL nucleolin 1.54947
PRKCA protein kinase C, alpha 1.54209
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.53889
PHB2 prohibitin 2 1.53506
NMT1 N-myristoyltransferase 1 1.53419
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 1.53111
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha 1.52661
IQGAP1 IQ motif containing GTPase activating protein 1 1.52645
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 1.525
CHD4 chromodomain helicase DNA binding protein 4 1.51741
UBXN6 UBX domain protein 6 1.5159
TRAPPC3 trafficking protein particle complex 3 1.5133
COL13A1 collagen, type XIII, alpha 1 1.51306
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) 1.50911
DPF2 D4, zinc and double PHD fingers family 2 1.50608
HMGN1 high mobility group nucleosome binding domain 1 1.50447
VPRBP Vpr (HIV-1) binding protein 1.50324
CTSD cathepsin D 1.50168
NIP7 NIP7, nucleolar pre-rRNA processing protein 1.50039
TOM1 target of myb1 (chicken) 1.49717
MRPL2 mitochondrial ribosomal protein L2 1.49272
GPC4 glypican 4 1.49229
INPP5K inositol polyphosphate-5-phosphatase K 1.49161
ZZZ3 zinc finger, ZZ-type containing 3 1.4912
NFXL1 nuclear transcription factor, X-box binding-like 1 1.48886
AXIN1 axin 1 1.48713
NAV2 neuron navigator 2 1.48669
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 1.48505
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) 1.48426
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 1.48355
NXN nucleoredoxin 1.48286
CRAT carnitine O-acetyltransferase 1.4828
EIF1B eukaryotic translation initiation factor 1B 1.48264
RANGAP1 Ran GTPase activating protein 1 1.48049
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.47931
TMEM11 transmembrane protein 11 1.47827
ENAH enabled homolog (Drosophila) 1.47676
ATG7 autophagy related 7 1.47628
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 1.47614
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 1.47566
COX17 COX17 cytochrome c oxidase copper chaperone 1.47406
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2 1.47283
PTP4A1 protein tyrosine phosphatase type IVA, member 1 1.4711
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 1.46747
RGS2 regulator of G-protein signaling 2 1.46674
ARID1A AT rich interactive domain 1A (SWI-like) 1.46629
AGRP agouti related neuropeptide 1.46328
SF3B3 splicing factor 3b, subunit 3, 130kDa 1.46088
SMAP2 small ArfGAP2 1.45845
QRICH1 glutamine-rich 1 1.4548
RAB11B RAB11B, member RAS oncogene family 1.4532
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 1.45223
STX4 syntaxin 4 1.45169

decreased expression

Symbol Name Standardized Value
TMEM208 transmembrane protein 208 -3.2525
CD59 CD59 molecule, complement regulatory protein -3.24464
VMP1 vacuole membrane protein 1 -2.88473
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase -2.69235
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 -2.53949
CDK4 cyclin-dependent kinase 4 -2.52252
CDK8 cyclin-dependent kinase 8 -2.5208
FKBP9 FK506 binding protein 9, 63 kDa -2.46895
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 -2.4655
RPS27A ribosomal protein S27a -2.42917
IL1R1 interleukin 1 receptor, type I -2.41427
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) -2.4118
LPIN1 lipin 1 -2.38069
GP5 glycoprotein V (platelet) -2.29926
DAZ2 deleted in azoospermia 2 -2.27878
ANKFY1 ankyrin repeat and FYVE domain containing 1 -2.26715
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.22383
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 -2.20759
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B -2.19902
STMN2 stathmin 2 -2.17857
TBC1D14 TBC1 domain family, member 14 -2.17393
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 -2.16204
ALG2 ALG2, alpha-1,3/1,6-mannosyltransferase -2.15705
GNPDA1 glucosamine-6-phosphate deaminase 1 -2.12636
TM2D2 TM2 domain containing 2 -2.12139
PROSC proline synthetase co-transcribed homolog (bacterial) -2.11495
PARL presenilin associated, rhomboid-like -2.114
ZNF131 zinc finger protein 131 -2.10258
REEP5 receptor accessory protein 5 -2.08216
TM9SF1 transmembrane 9 superfamily member 1 -2.0818
PROCR protein C receptor, endothelial -2.06897
RP9 retinitis pigmentosa 9 (autosomal dominant) -2.06826
SYNJ2BP synaptojanin 2 binding protein -2.05675
DNM1L dynamin 1-like -2.05005
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial -2.02448
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -2.02295
HOXC8 homeobox C8 -2.01711
FBXW4 F-box and WD repeat domain containing 4 -2.01053
PEX11B peroxisomal biogenesis factor 11 beta -2.00932
INTS3 integrator complex subunit 3 -2.00212
ITGB7 integrin, beta 7 -1.98556
JKAMP JNK1/MAPK8-associated membrane protein -1.97828
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2 -1.97646
HES2 hes family bHLH transcription factor 2 -1.96844
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit -1.96591
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 -1.96426
AK4 adenylate kinase 4 -1.95334
C7ORF55 chromosome 7 open reading frame 55 -1.94444
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) -1.94072
COPE coatomer protein complex, subunit epsilon -1.92996
HIF3A hypoxia inducible factor 3, alpha subunit -1.92495
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) -1.91968
MPV17 MpV17 mitochondrial inner membrane protein -1.91946
GOLM1 golgi membrane protein 1 -1.91054
CUL7 cullin 7 -1.91051
RSU1 Ras suppressor protein 1 -1.90966
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A -1.90233
NUP50 nucleoporin 50kDa -1.89992
BRAP BRCA1 associated protein -1.89837
CPT2 carnitine palmitoyltransferase 2 -1.89636
CSF1 colony stimulating factor 1 (macrophage) -1.89467
DRD2 dopamine receptor D2 -1.87802
SOCS5 suppressor of cytokine signaling 5 -1.87108
DPYSL2 dihydropyrimidinase-like 2 -1.86704
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit -1.86062
SREBF1 sterol regulatory element binding transcription factor 1 -1.85848
RBM15 RNA binding motif protein 15 -1.85371
NDFIP2 Nedd4 family interacting protein 2 -1.85238
ZNRD1 zinc ribbon domain containing 1 -1.849
ZFYVE19 zinc finger, FYVE domain containing 19 -1.8263
SIPA1 signal-induced proliferation-associated 1 -1.825
RIN2 Ras and Rab interactor 2 -1.82003
CYFIP1 cytoplasmic FMR1 interacting protein 1 -1.81883
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 -1.81607
ATOX1 antioxidant 1 copper chaperone -1.81535
SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae) -1.81495
WIZ widely interspaced zinc finger motifs -1.79827
EGFL8 EGF-like-domain, multiple 8 -1.79723
WLS wntless Wnt ligand secretion mediator -1.79603
PTCH1 patched 1 -1.79568
CKB creatine kinase, brain -1.78276
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -1.78264
TMX1 thioredoxin-related transmembrane protein 1 -1.77872
FBXO45 F-box protein 45 -1.77586
SIX5 SIX homeobox 5 -1.77182
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase -1.77055
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae) -1.76851
RGS3 regulator of G-protein signaling 3 -1.76686
BCAT2 branched chain amino-acid transaminase 2, mitochondrial -1.76083
NOG noggin -1.75046
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -1.74927
ATG12 autophagy related 12 -1.74294
NEDD1 neural precursor cell expressed, developmentally down-regulated 1 -1.73932
FLOT1 flotillin 1 -1.73061
OSTF1 osteoclast stimulating factor 1 -1.72993
RAB4A RAB4A, member RAS oncogene family -1.72829
GOLGA3 golgin A3 -1.72627
ELOF1 elongation factor 1 homolog (S. cerevisiae) -1.72132
SELK selenoprotein K -1.72081
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 -1.72062
ARMC10 armadillo repeat containing 10 -1.71577
RIC8A RIC8 guanine nucleotide exchange factor A -1.71197
HOPX HOP homeobox -1.71169
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa -1.70649
NCOA1 nuclear receptor coactivator 1 -1.70443
GLTSCR2 glioma tumor suppressor candidate region gene 2 -1.70337
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 -1.69788
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -1.6945
CXXC1 CXXC finger protein 1 -1.69375
CTNND1 catenin (cadherin-associated protein), delta 1 -1.69146
KLC1 kinesin light chain 1 -1.68876
VRK3 vaccinia related kinase 3 -1.68316
RPS29 ribosomal protein S29 -1.68046
NECAP1 NECAP endocytosis associated 1 -1.68027
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) -1.67967
NUDT16L1 nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1 -1.67813
C11ORF31 chromosome 11 open reading frame 31 -1.6775
FOXRED1 FAD-dependent oxidoreductase domain containing 1 -1.67326
PPIA peptidylprolyl isomerase A (cyclophilin A) -1.67075
TOMM7 translocase of outer mitochondrial membrane 7 homolog (yeast) -1.66918
PLK2 polo-like kinase 2 -1.66794
IL9R interleukin 9 receptor -1.66705
RER1 retention in endoplasmic reticulum sorting receptor 1 -1.66228
SYT3 synaptotagmin III -1.65673
ACTB actin, beta -1.65552
LEFTY1 left-right determination factor 1 -1.6542
EFHD2 EF-hand domain family, member D2 -1.64301
MBTD1 mbt domain containing 1 -1.63975
CRCP CGRP receptor component -1.6385
DTYMK deoxythymidylate kinase (thymidylate kinase) -1.63786
IPO11 importin 11 -1.62988
IFRD2 interferon-related developmental regulator 2 -1.62911
PALM paralemmin -1.62868
GLE1 GLE1 RNA export mediator -1.62712
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide -1.62642
OSBPL5 oxysterol binding protein-like 5 -1.62539
MERTK MER proto-oncogene, tyrosine kinase -1.62483
ACP6 acid phosphatase 6, lysophosphatidic -1.62458
TENM4 teneurin transmembrane protein 4 -1.62455
PARP16 poly (ADP-ribose) polymerase family, member 16 -1.6245
FBXL3 F-box and leucine-rich repeat protein 3 -1.62343
ANAPC1 anaphase promoting complex subunit 1 -1.62126
C9ORF64 chromosome 9 open reading frame 64 -1.62101
EXTL3 exostosin-like glycosyltransferase 3 -1.62
BLVRA biliverdin reductase A -1.61881
EDF1 endothelial differentiation-related factor 1 -1.61749
MSX2 msh homeobox 2 -1.61739
SOD1 superoxide dismutase 1, soluble -1.61332
ADCY4 adenylate cyclase 4 -1.61239
THAP4 THAP domain containing 4 -1.61026
G0S2 G0/G1 switch 2 -1.60996
AP3S1 adaptor-related protein complex 3, sigma 1 subunit -1.6089
SEC31A SEC31 homolog A (S. cerevisiae) -1.60497
CASP9 caspase 9, apoptosis-related cysteine peptidase -1.60346
RPS26 ribosomal protein S26 -1.59567
REG1A regenerating islet-derived 1 alpha -1.59408
GSN gelsolin -1.59012
GKAP1 G kinase anchoring protein 1 -1.58907
ITSN1 intersectin 1 (SH3 domain protein) -1.588
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase -1.58779
MRPS36 mitochondrial ribosomal protein S36 -1.58186
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta -1.57876
CTSV cathepsin V -1.57411
CDK18 cyclin-dependent kinase 18 -1.57102
RNH1 ribonuclease/angiogenin inhibitor 1 -1.56889
CNPY2 canopy FGF signaling regulator 2 -1.56841
ZNF322 zinc finger protein 322 -1.5664
FAM8A1 family with sequence similarity 8, member A1 -1.55969
PGM2 phosphoglucomutase 2 -1.55916
PI4K2A phosphatidylinositol 4-kinase type 2 alpha -1.5582
TTC17 tetratricopeptide repeat domain 17 -1.554
TM9SF3 transmembrane 9 superfamily member 3 -1.54888
MDH1 malate dehydrogenase 1, NAD (soluble) -1.54483
MITF microphthalmia-associated transcription factor -1.53938
DCAF11 DDB1 and CUL4 associated factor 11 -1.5352
YY1 YY1 transcription factor -1.53421
S100PBP S100P binding protein -1.53249
RPL10 ribosomal protein L10 -1.53076
CHMP2B charged multivesicular body protein 2B -1.53052
SLC39A1 solute carrier family 39 (zinc transporter), member 1 -1.5292
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) -1.52662
AP1M1 adaptor-related protein complex 1, mu 1 subunit -1.52613
FZD8 frizzled class receptor 8 -1.5244
C1QTNF1 C1q and tumor necrosis factor related protein 1 -1.5236
PPP4R2 protein phosphatase 4, regulatory subunit 2 -1.52193
CWC15 CWC15 spliceosome-associated protein -1.52111
SNX9 sorting nexin 9 -1.51424
NKX2-8 NK2 homeobox 8 -1.51326
TM4SF1 transmembrane 4 L six family member 1 -1.51187
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -1.51117
TUBB3 tubulin, beta 3 class III -1.51057
APLNR apelin receptor -1.50954
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -1.50913
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -1.50824
NDRG1 N-myc downstream regulated 1 -1.50665
RFC1 replication factor C (activator 1) 1, 145kDa -1.50656
JAM3 junctional adhesion molecule 3 -1.50551
TXNRD2 thioredoxin reductase 2 -1.5053
CDC16 cell division cycle 16 -1.50524
PRPF38A pre-mRNA processing factor 38A -1.50281
RPL5 ribosomal protein L5 -1.49899
MFN1 mitofusin 1 -1.49794
PPOX protoporphyrinogen oxidase -1.49474
RPS12 ribosomal protein S12 -1.4942
MYDGF myeloid-derived growth factor -1.49381
C16ORF74 chromosome 16 open reading frame 74 -1.49207
ARHGAP1 Rho GTPase activating protein 1 -1.49202
COPZ2 coatomer protein complex, subunit zeta 2 -1.48933
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 -1.48589
UNG uracil-DNA glycosylase -1.48299
SDC3 syndecan 3 -1.48086
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B -1.47988
CDKN3 cyclin-dependent kinase inhibitor 3 -1.47838
CDH4 cadherin 4, type 1, R-cadherin (retinal) -1.47728
CRYGS crystallin, gamma S -1.47437
SF3A3 splicing factor 3a, subunit 3, 60kDa -1.47376
GUCY2C guanylate cyclase 2C -1.47012
MNAT1 MNAT CDK-activating kinase assembly factor 1 -1.46992
GRIK5 glutamate receptor, ionotropic, kainate 5 -1.46776
GBA glucosidase, beta, acid -1.46578
HK2 hexokinase 2 -1.46051
SRSF2 serine/arginine-rich splicing factor 2 -1.45954
RBPJ recombination signal binding protein for immunoglobulin kappa J region -1.4582
MEMO1 mediator of cell motility 1 -1.45699
PTGES prostaglandin E synthase -1.45601
RGS19 regulator of G-protein signaling 19 -1.45528
MBD6 methyl-CpG binding domain protein 6 -1.45504
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) -1.45485
UBA1 ubiquitin-like modifier activating enzyme 1 -1.45267
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa -1.45081
CD200 CD200 molecule -1.44871
SETD6 SET domain containing 6 -1.44419
RRAGC Ras-related GTP binding C -1.44321
MPHOSPH9 M-phase phosphoprotein 9 -1.44266
RNF20 ring finger protein 20, E3 ubiquitin protein ligase -1.44245
DGAT1 diacylglycerol O-acyltransferase 1 -1.44165
TAGLN transgelin -1.44122
ESR2 estrogen receptor 2 (ER beta) -1.43958
MAP2K6 mitogen-activated protein kinase kinase 6 -1.43513
METTL20 methyltransferase like 20 -1.43363
CNOT1 CCR4-NOT transcription complex, subunit 1 -1.43309
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 -1.43285
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 -1.43135
ITK IL2-inducible T-cell kinase -1.43014
NR1D1 nuclear receptor subfamily 1, group D, member 1 -1.42526
PLXNA1 plexin A1 -1.42486
TBCEL tubulin folding cofactor E-like -1.42373
PTGDS prostaglandin D2 synthase 21kDa (brain) -1.4216
HIST1H3F histone cluster 1, H3f -1.4208
NT5E 5'-nucleotidase, ecto (CD73) -1.41708
RNASEH2B ribonuclease H2, subunit B -1.41663
GOLGA7 golgin A7 -1.4159
ANAPC11 anaphase promoting complex subunit 11 -1.41389
WNT5B wingless-type MMTV integration site family, member 5B -1.41221
DMBT1 deleted in malignant brain tumors 1 -1.41197
GON4L gon-4-like (C. elegans) -1.41188
DDX49 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 -1.40759
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae) -1.40711
LRWD1 leucine-rich repeats and WD repeat domain containing 1 -1.40406
HLTF helicase-like transcription factor -1.40386
KHK ketohexokinase (fructokinase) -1.40277
RNF4 ring finger protein 4 -1.40102
RPS24 ribosomal protein S24 -1.40092
TMEM109 transmembrane protein 109 -1.39987
GPX3 glutathione peroxidase 3 -1.39981
FMNL3 formin-like 3 -1.39813
CSHL1 chorionic somatomammotropin hormone-like 1 -1.39641
CTPS1 CTP synthase 1 -1.39621
PCGF2 polycomb group ring finger 2 -1.39538
MAST3 microtubule associated serine/threonine kinase 3 -1.39536
CLPTM1L CLPTM1-like -1.39228
TEF thyrotrophic embryonic factor -1.38979
PHLDB1 pleckstrin homology-like domain, family B, member 1 -1.38946
GATAD2A GATA zinc finger domain containing 2A -1.38768
MLX MLX, MAX dimerization protein -1.38721
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) -1.38672
UTS2R urotensin 2 receptor -1.38559
ARRB1 arrestin, beta 1 -1.38282
FAM71D family with sequence similarity 71, member D -1.3814
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa -1.3799
NICN1 nicolin 1 -1.37713
TIMP3 TIMP metallopeptidase inhibitor 3 -1.37699
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 -1.37566
IHH indian hedgehog -1.37364
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -1.37175
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic -1.36993
DPP8 dipeptidyl-peptidase 8 -1.36731
SOCS2 suppressor of cytokine signaling 2 -1.36584
ZBTB45 zinc finger and BTB domain containing 45 -1.36572
PPP1R7 protein phosphatase 1, regulatory subunit 7 -1.36272
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 -1.36199
SFXN5 sideroflexin 5 -1.36136
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 -1.35824
INTS4 integrator complex subunit 4 -1.35775
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -1.35753
ZKSCAN3 zinc finger with KRAB and SCAN domains 3 -1.35743
SIGMAR1 sigma non-opioid intracellular receptor 1 -1.35652
ANXA3 annexin A3 -1.35358
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) -1.35338
PPP1R12C protein phosphatase 1, regulatory subunit 12C -1.35189