Neointimal Hyperplasia Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C4049446
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Genes

182 genes associated with the disease Neointimal Hyperplasia in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACCS 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)
ACSS2 acyl-CoA synthetase short-chain family member 2
ACTB actin, beta
ADIPOQ adiponectin, C1Q and collagen domain containing
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT1S1 AKT1 substrate 1 (proline-rich)
ANGPT2 angiopoietin 2
ANGPTL2 angiopoietin-like 2
APOE apolipoprotein E
BMP2 bone morphogenetic protein 2
BMP3 bone morphogenetic protein 3
BSG basigin (Ok blood group)
CALCA calcitonin-related polypeptide alpha
CASP1 caspase 1, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CAVIN1 caveolae associated protein 1
CCL2 chemokine (C-C motif) ligand 2
CCN1 cellular communication network factor 1
CCR2 chemokine (C-C motif) receptor 2
CD36 CD36 molecule (thrombospondin receptor)
CD59 CD59 molecule, complement regulatory protein
CDK1 cyclin-dependent kinase 1
CDK4 cyclin-dependent kinase 4
CDK9 cyclin-dependent kinase 9
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CETP cholesteryl ester transfer protein, plasma
CHGA chromogranin A
CIB1 calcium and integrin binding 1 (calmyrin)
CKLF chemokine-like factor
CLU clusterin
COX2
CREG1 cellular repressor of E1A-stimulated genes 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSK cathepsin K
CTSL cathepsin L
CTSS cathepsin S
DAPK1 death-associated protein kinase 1
DAPK3 death-associated protein kinase 3
DBN1 drebrin 1
DCN decorin
DCTN6 dynactin 6
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DOCK2 dedicator of cytokinesis 2
DYM dymeclin
EFNB2 ephrin-B2
ELN elastin
ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8
EPHB4 EPH receptor B4
EPO erythropoietin
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F10 coagulation factor X
FHL2 four and a half LIM domains 2
FMOD fibromodulin
FOXO3 forkhead box O3
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GATA4 GATA binding protein 4
GATA6 GATA binding protein 6
GDNF glial cell derived neurotrophic factor
GIP gastric inhibitory polypeptide
GJA1 gap junction protein, alpha 1, 43kDa
HDAC2 histone deacetylase 2
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMGB1 high mobility group box 1
HMGB2 high mobility group box 2
HMOX1 heme oxygenase 1
IER3 immediate early response 3
IFI27 interferon, alpha-inducible protein 27
IFI35 interferon-induced protein 35
IFNG interferon, gamma
IL1B interleukin 1, beta
IL6 interleukin 6
IRF1 interferon regulatory factor 1
ISYNA1 inositol-3-phosphate synthase 1
JAK3 Janus kinase 3
KAT2B K(lysine) acetyltransferase 2B
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KDM3A lysine (K)-specific demethylase 3A
KDM6B lysine (K)-specific demethylase 6B
KLF4 Kruppel-like factor 4 (gut)
LEP leptin
LGALS1 lectin, galactoside-binding, soluble, 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK6 mitogen-activated protein kinase 6
MARCKS myristoylated alanine-rich protein kinase C substrate
MBD2 methyl-CpG binding domain protein 2
MFAP4 microfibrillar-associated protein 4
MFN2 mitofusin 2
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP9 matrix metallopeptidase 9
MMRN1 multimerin 1
MSRA methionine sulfoxide reductase A
MYBPH myosin binding protein H
MYH11 myosin, heavy chain 11, smooth muscle
MYO1E myosin IE
MYO1F myosin IF
NCF1 neutrophil cytosolic factor 1
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOXA1 NADPH oxidase activator 1
NPPC natriuretic peptide C
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRP1 neuropilin 1
NUCB2 nucleobindin 2
PCNA proliferating cell nuclear antigen
PDZK1 PDZ domain containing 1
PEA15 phosphoprotein enriched in astrocytes 15
PECAM1 platelet/endothelial cell adhesion molecule 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLA2G15 phospholipase A2, group XV
PLAU plasminogen activator, urokinase
PNPLA2 patatin-like phospholipase domain containing 2
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
PPARG peroxisome proliferator-activated receptor gamma
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKG1 protein kinase, cGMP-dependent, type I
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTCH1 patched 1
PTEN phosphatase and tensin homolog
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPRJ protein tyrosine phosphatase, receptor type, J
RAD50 RAD50 homolog (S. cerevisiae)
REN renin
REST RE1-silencing transcription factor
RNF10 ring finger protein 10
S100A12 S100 calcium binding protein A12
S100B S100 calcium binding protein B
S1PR1 sphingosine-1-phosphate receptor 1
S1PR3 sphingosine-1-phosphate receptor 3
SARAF store-operated calcium entry-associated regulatory factor
SELE selectin E
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SERP1 stress-associated endoplasmic reticulum protein 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SETD2 SET domain containing 2
SIRT1 sirtuin 1
SIRT3 sirtuin 3
SMAD3 SMAD family member 3
SOS1 son of sevenless homolog 1 (Drosophila)
SPAG11A sperm associated antigen 11A
SPAG11B sperm associated antigen 11B
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STIM1 stromal interaction molecule 1
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TAGLN transgelin
TGFB1 transforming growth factor, beta 1
TGM2 transglutaminase 2
TICAM2 toll-like receptor adaptor molecule 2
TMED7 transmembrane emp24 protein transport domain containing 7
TMED7-TICAM2 TMED7-TICAM2 readthrough
TNF tumor necrosis factor
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNFSF12-TNFSF13 TNFSF12-TNFSF13 readthrough
TP53 tumor protein p53
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TSPO translocator protein (18kDa)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VEGFA vascular endothelial growth factor A
VWF von Willebrand factor
XBP1 X-box binding protein 1