Neonatal Abstinence Syndrome Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A withdrawal disorder that is characterized by a group of problems that occur in a newborn who was exposed to addictive illegal or prescription drugs while in the mother's womb or postnatally following the discontinuance of drug treatment. (Human Disease Ontology, DOID_9828)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D009357
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Genes

42 genes/proteins associated with the disease Neonatal Abstinence Syndrome from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
OPRM1 opioid receptor, mu 1 1.82919
BDNF brain-derived neurotrophic factor 1.69617
OPRK1 opioid receptor, kappa 1 1.65908
DRD2 dopamine receptor D2 1.58678
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.58607
OPRD1 opioid receptor, delta 1 1.57354
FOS FBJ murine osteosarcoma viral oncogene homolog 1.43537
MAPK3 mitogen-activated protein kinase 3 1.42266
MAPK1 mitogen-activated protein kinase 1 1.41559
SIGMAR1 sigma non-opioid intracellular receptor 1 1.37475
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.30788
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.28088
TNF tumor necrosis factor 1.27286
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.25307
EGR1 early growth response 1 1.21823
IL2 interleukin 2 1.21206
PDYN prodynorphin 1.19047
NEFH neurofilament, heavy polypeptide 1.17101
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.16933
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 1.13793
CES2 carboxylesterase 2 1.13279
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.13075
CREB1 cAMP responsive element binding protein 1 1.12703
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 1.12703
GSK3B glycogen synthase kinase 3 beta 1.11396
BAX BCL2-associated X protein 1.10872
CRH corticotropin releasing hormone 1.10527
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.08797
NUPR1 nuclear protein, transcriptional regulator, 1 1.08655
GRM1 glutamate receptor, metabotropic 1 1.08231
DRD4 dopamine receptor D4 1.07983
ENHO energy homeostasis associated 1.06297
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 1.06261
IL1A interleukin 1, alpha 1.05721
HOMER1 homer scaffolding protein 1 1.05312
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 1.04978
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.03976
IL6 interleukin 6 1.02559
JUNB jun B proto-oncogene 1.02447
RGS4 regulator of G-protein signaling 4 1.02151
MAPK8 mitogen-activated protein kinase 8 1.01512
MAP2 microtubule-associated protein 2 1.01361