Nephritis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0027697
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Genes

276 genes associated with the disease Nephritis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACE2 angiotensin I converting enzyme 2
ACKR2 atypical chemokine receptor 2
ACR acrosin
ACTN4 actinin, alpha 4
ADIPOQ adiponectin, C1Q and collagen domain containing
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AIF1 allograft inflammatory factor 1
AIM2 absent in melanoma 2
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
ALB albumin
ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
ALMS1 Alstrom syndrome protein 1
ALOX15 arachidonate 15-lipoxygenase
ANGPT1 angiopoietin 1
ANXA2 annexin A2
ATN1 atrophin 1
AXL AXL receptor tyrosine kinase
B2M beta-2-microglobulin
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCL2 B-cell CLL/lymphoma 2
BGN biglycan
BRAF B-Raf proto-oncogene, serine/threonine kinase
BTG3 BTG family, member 3
BTK Bruton agammaglobulinemia tyrosine kinase
C1QA complement component 1, q subcomponent, A chain
C1R complement component 1, r subcomponent
C3 complement component 3
CAMK4 calcium/calmodulin-dependent protein kinase IV
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAST calpastatin
CAV1 caveolin 1, caveolae protein, 22kDa
CCL2 chemokine (C-C motif) ligand 2
CCL3 chemokine (C-C motif) ligand 3
CCL5 chemokine (C-C motif) ligand 5
CCN2 cellular communication network factor 2
CCND2 cyclin D2
CCR1 chemokine (C-C motif) receptor 1
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD151 CD151 molecule (Raph blood group)
CD1C CD1c molecule
CD274 CD274 molecule
CD28 CD28 molecule
CD34 CD34 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CD46 CD46 molecule, complement regulatory protein
CD86 CD86 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CFH complement factor H
CIC capicua transcriptional repressor
CLDN2 claudin 2
COL4A2 collagen, type IV, alpha 2
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL4A4 collagen, type IV, alpha 4
COL4A5 collagen, type IV, alpha 5
COX1
COX2
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CRP C-reactive protein, pentraxin-related
CRYGD crystallin, gamma D
CST3 cystatin C
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR3 chemokine (C-X-C motif) receptor 3
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
DNASE1 deoxyribonuclease I
DNASE1L3 deoxyribonuclease I-like 3
EDN1 endothelin 1
EGFR epidermal growth factor receptor
ELANE elastase, neutrophil expressed
EMB embigin
ENO1 enolase 1, (alpha)
ERN1 endoplasmic reticulum to nucleus signaling 1
ERVW-1 endogenous retrovirus group W, member 1
ESR1 estrogen receptor 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FAS Fas cell surface death receptor
FCAR Fc fragment of IgA receptor
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FGF2 fibroblast growth factor 2 (basic)
FGF23 fibroblast growth factor 23
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLII flightless I homolog (Drosophila)
FN1 fibronectin 1
FOXP3 forkhead box P3
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GAS6 growth arrest-specific 6
GATA3 GATA binding protein 3
GORASP1 golgi reassembly stacking protein 1, 65kDa
GPBAR1 G protein-coupled bile acid receptor 1
GREM1 gremlin 1, DAN family BMP antagonist
GSTT1 glutathione S-transferase theta 1
HAMP hepcidin antimicrobial peptide
HAVCR1 hepatitis A virus cellular receptor 1
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGB1 high mobility group box 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPE1 heat shock 10kDa protein 1
HVCN1 hydrogen voltage gated channel 1
ICAM1 intercellular adhesion molecule 1
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IGBP1 immunoglobulin (CD79A) binding protein 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL10 interleukin 10
IL10RA interleukin 10 receptor, alpha
IL11 interleukin 11
IL17A interleukin 17A
IL17F interleukin 17F
IL17RD interleukin 17 receptor D
IL18 interleukin 18
IL18BP interleukin 18 binding protein
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL21 interleukin 21
IL22 interleukin 22
IL23A interleukin 23, alpha subunit p19
IL24 interleukin 24
IL4 interleukin 4
IL5 interleukin 5
IL6 interleukin 6
IL7R interleukin 7 receptor
IRAK1 interleukin-1 receptor-associated kinase 1
IRF8 interferon regulatory factor 8
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KDR kinase insert domain receptor
KLK4 kallikrein-related peptidase 4
LCN2 lipocalin 2
LEPR leptin receptor
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS9 lectin, galactoside-binding, soluble, 9
LRRK2 leucine-rich repeat kinase 2
LST1 leukocyte specific transcript 1
LTA lymphotoxin alpha
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK3 mitogen-activated protein kinase 3
MBL2 mannose-binding lectin (protein C) 2, soluble
MET MET proto-oncogene, receptor tyrosine kinase
MMP3 matrix metallopeptidase 3
MMP8 matrix metallopeptidase 8
MPO myeloperoxidase
MT1A metallothionein 1A
MT1B metallothionein 1B
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1M metallothionein 1M
MT1X metallothionein 1X
MT2A metallothionein 2A
MTNR1A melatonin receptor 1A
MYD88 myeloid differentiation primary response 88
MYH9 myosin, heavy chain 9, non-muscle
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NEU1 sialidase 1 (lysosomal sialidase)
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NLRP1 NLR family, pyrin domain containing 1
NLRP3 NLR family, pyrin domain containing 3
NLRP6 NLR family, pyrin domain containing 6
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOV nephroblastoma overexpressed
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
OGG1 8-oxoguanine DNA glycosylase
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1
PADI4 peptidyl arginine deiminase, type IV
PAX2 paired box 2
PDCD1 programmed cell death 1
PDGFB platelet-derived growth factor beta polypeptide
PF4 platelet factor 4
PLA2G1B phospholipase A2, group IB (pancreas)
PLAU plasminogen activator, urokinase
PLB1 phospholipase B1
PLG plasminogen
PODXL podocalyxin-like
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PROCR protein C receptor, endothelial
PTEN phosphatase and tensin homolog
PTGDR2 prostaglandin D2 receptor 2
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRO protein tyrosine phosphatase, receptor type, O
PTX3 pentraxin 3, long
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
RBM45 RNA binding motif protein 45
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SIRT1 sirtuin 1
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SMAD6 SMAD family member 6
SMAD7 SMAD family member 7
SNRPA small nuclear ribonucleoprotein polypeptide A
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa
SOCS1 suppressor of cytokine signaling 1
SOX9 SRY (sex determining region Y)-box 9
SPAG11A sperm associated antigen 11A
SPAG11B sperm associated antigen 11B
SPP1 secreted phosphoprotein 1
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STAT4 signal transducer and activator of transcription 4
SUMO4 small ubiquitin-like modifier 4
SYT1 synaptotagmin I
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THEMIS2 thymocyte selection associated family member 2
THRA thyroid hormone receptor, alpha
THY1 Thy-1 cell surface antigen
TIMP4 TIMP metallopeptidase inhibitor 4
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR7 toll-like receptor 7
TLR9 toll-like receptor 9
TM7SF2 transmembrane 7 superfamily member 2
TNF tumor necrosis factor
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNIP1 TNFAIP3 interacting protein 1
TRAP1 TNF receptor-associated protein 1
TREX1 three prime repair exonuclease 1
TXNIP thioredoxin interacting protein
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UMOD uromodulin
VANGL2 VANGL planar cell polarity protein 2
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VTCN1 V-set domain containing T cell activation inhibitor 1
WNK1 WNK lysine deficient protein kinase 1
XK X-linked Kx blood group
YBX1 Y box binding protein 1
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta