Nephroblastoma_Renal Tissue_GSE2712 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE2712
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Genes

600 genes differentially expressed during Nephroblastoma_Renal Tissue_GSE2712 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
TTF1 transcription termination factor, RNA polymerase I 3.008
RPS19 ribosomal protein S19 2.93691
POP4 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) 2.7016
SOBP sine oculis binding protein homolog (Drosophila) 2.68388
SUMO2 small ubiquitin-like modifier 2 2.68058
FPGS folylpolyglutamate synthase 2.67788
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 2.51936
SCNM1 sodium channel modifier 1 2.51675
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 2.48863
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 2.47799
HARS2 histidyl-tRNA synthetase 2, mitochondrial 2.45142
KCMF1 potassium channel modulatory factor 1 2.38111
CIB1 calcium and integrin binding 1 (calmyrin) 2.32808
EIF3H eukaryotic translation initiation factor 3, subunit H 2.26779
LAPTM4B lysosomal protein transmembrane 4 beta 2.26625
NMB neuromedin B 2.21138
DGUOK deoxyguanosine kinase 2.17161
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) 2.16861
ESYT1 extended synaptotagmin-like protein 1 2.1537
DRG2 developmentally regulated GTP binding protein 2 2.14686
CSNK1A1 casein kinase 1, alpha 1 2.14015
RPS6 ribosomal protein S6 2.12174
TEX10 testis expressed 10 2.11356
RPL39 ribosomal protein L39 2.10309
STAMBP STAM binding protein 2.09847
ELP3 elongator acetyltransferase complex subunit 3 2.09418
RPS27L ribosomal protein S27-like 2.08596
PTCD1 pentatricopeptide repeat domain 1 2.08547
TUBA1A tubulin, alpha 1a 2.08032
TNIP2 TNFAIP3 interacting protein 2 2.0781
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 2.07524
EMG1 EMG1 N1-specific pseudouridine methyltransferase 2.06573
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 2.05397
RPS23 ribosomal protein S23 2.04037
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 2.03682
UNC5B unc-5 homolog B (C. elegans) 2.03433
SND1 staphylococcal nuclease and tudor domain containing 1 2.02084
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 2.00806
UQCRH ubiquinol-cytochrome c reductase hinge protein 1.98005
LRPPRC leucine-rich pentatricopeptide repeat containing 1.96793
SUMO4 small ubiquitin-like modifier 4 1.93837
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.93663
NXPH4 neurexophilin 4 1.93127
VPS33B vacuolar protein sorting 33 homolog B (yeast) 1.91954
GRAMD4 GRAM domain containing 4 1.91241
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 1.91241
UBE2D2 ubiquitin-conjugating enzyme E2D 2 1.90183
RPS27 ribosomal protein S27 1.89295
RBPJ recombination signal binding protein for immunoglobulin kappa J region 1.89171
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa 1.88802
PIGT phosphatidylinositol glycan anchor biosynthesis, class T 1.88415
GFRA4 GDNF family receptor alpha 4 1.87357
OSTM1 osteopetrosis associated transmembrane protein 1 1.87151
SFN stratifin 1.86734
RAD51C RAD51 paralog C 1.85723
PRDX2 peroxiredoxin 2 1.85477
TNPO1 transportin 1 1.84921
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) 1.84637
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 1.83923
RALGDS ral guanine nucleotide dissociation stimulator 1.83914
JTB jumping translocation breakpoint 1.83596
KIAA1324 KIAA1324 1.82826
CNPY2 canopy FGF signaling regulator 2 1.82704
GPBP1L1 GC-rich promoter binding protein 1-like 1 1.81433
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 1.81293
PTGES3 prostaglandin E synthase 3 (cytosolic) 1.81028
PPP2R5D protein phosphatase 2, regulatory subunit B', delta 1.80696
RPAP1 RNA polymerase II associated protein 1 1.80344
PARL presenilin associated, rhomboid-like 1.80284
ATP13A1 ATPase type 13A1 1.80132
COMMD3 COMM domain containing 3 1.79202
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) 1.78605
NFS1 NFS1 cysteine desulfurase 1.7846
HLA-F major histocompatibility complex, class I, F 1.78039
PCCB propionyl CoA carboxylase, beta polypeptide 1.77781
SNRPE small nuclear ribonucleoprotein polypeptide E 1.777
TRAPPC2 trafficking protein particle complex 2 1.7709
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.76944
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 1.76801
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 1.76419
MORF4L1 mortality factor 4 like 1 1.76005
SKP1 S-phase kinase-associated protein 1 1.75852
NKAIN1 Na+/K+ transporting ATPase interacting 1 1.75683
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein 1.75238
RPS10 ribosomal protein S10 1.74881
ACVR1 activin A receptor, type I 1.74744
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa 1.7446
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 1.74181
NUDC nudC nuclear distribution protein 1.7391
NFIL3 nuclear factor, interleukin 3 regulated 1.73762
CHMP7 charged multivesicular body protein 7 1.73716
RPL19 ribosomal protein L19 1.7356
NUP85 nucleoporin 85kDa 1.73362
MORF4L2 mortality factor 4 like 2 1.72974
SEC16A SEC16 homolog A (S. cerevisiae) 1.72738
VAV1 vav 1 guanine nucleotide exchange factor 1.7263
KIF1B kinesin family member 1B 1.71518
RPS3A ribosomal protein S3A 1.71344
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.70756
MRPL34 mitochondrial ribosomal protein L34 1.70361
POLR1E polymerase (RNA) I polypeptide E, 53kDa 1.70056
UFC1 ubiquitin-fold modifier conjugating enzyme 1 1.69823
DBF4B DBF4 zinc finger B 1.69226
RPL7A ribosomal protein L7a 1.68979
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) 1.6873
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 1.68421
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 1.68359
LONP1 lon peptidase 1, mitochondrial 1.67687
TBC1D22A TBC1 domain family, member 22A 1.67422
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 1.66771
C17ORF70 chromosome 17 open reading frame 70 1.66078
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 1.65603
TPT1 tumor protein, translationally-controlled 1 1.64168
NACA nascent polypeptide-associated complex alpha subunit 1.64111
USP5 ubiquitin specific peptidase 5 (isopeptidase T) 1.64006
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 1.63436
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa 1.63096
WIPI2 WD repeat domain, phosphoinositide interacting 2 1.63084
HCLS1 hematopoietic cell-specific Lyn substrate 1 1.6214
RPL17 ribosomal protein L17 1.61769
THOP1 thimet oligopeptidase 1 1.61467
OSBPL10 oxysterol binding protein-like 10 1.6097
RPS15 ribosomal protein S15 1.60908
BRMS1 breast cancer metastasis suppressor 1 1.60898
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 1.60641
HDGFRP3 hepatoma-derived growth factor, related protein 3 1.60069
RPS3 ribosomal protein S3 1.59691
PCGF3 polycomb group ring finger 3 1.59681
CSNK2A1 casein kinase 2, alpha 1 polypeptide 1.59547
TMEM160 transmembrane protein 160 1.59229
HIATL1 hippocampus abundant transcript-like 1 1.59197
BRD9 bromodomain containing 9 1.5883
YY2 YY2 transcription factor 1.58824
RPSAP20 ribosomal protein SA pseudogene 20 1.58698
ACTG1 actin gamma 1 1.57977
RPS17 ribosomal protein S17 1.57613
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2 1.57599
SRSF9 serine/arginine-rich splicing factor 9 1.57557
PHF3 PHD finger protein 3 1.57217
PHB2 prohibitin 2 1.57171
CAND1 cullin-associated and neddylation-dissociated 1 1.57134
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4 1.57131
ASNA1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) 1.57097
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing 1.56893
DNAH17 dynein, axonemal, heavy chain 17 1.56673
RPS20 ribosomal protein S20 1.56311
MRPS30 mitochondrial ribosomal protein S30 1.56187
MOB4 MOB family member 4, phocein 1.56113
UCK2 uridine-cytidine kinase 2 1.5598
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 1.55543
NKRF NFKB repressing factor 1.55208
CALCOCO2 calcium binding and coiled-coil domain 2 1.5504
DGCR14 DiGeorge syndrome critical region gene 14 1.54974
MAP2 microtubule-associated protein 2 1.54817
TIMP1 TIMP metallopeptidase inhibitor 1 1.548
C15ORF39 chromosome 15 open reading frame 39 1.54232
THAP10 THAP domain containing 10 1.53601
ZC3H13 zinc finger CCCH-type containing 13 1.53478
PCGF2 polycomb group ring finger 2 1.53355
SLC39A1 solute carrier family 39 (zinc transporter), member 1 1.52892
UBAP2L ubiquitin associated protein 2-like 1.52852
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 1.52797
IGKC immunoglobulin kappa constant 1.52624
PTPRM protein tyrosine phosphatase, receptor type, M 1.52519
RPS21 ribosomal protein S21 1.5246
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 1.52158
ARID4A AT rich interactive domain 4A (RBP1-like) 1.51959
IPP intracisternal A particle-promoted polypeptide 1.51902
CYFIP1 cytoplasmic FMR1 interacting protein 1 1.51676
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) 1.51428
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 1.51295
RPL9 ribosomal protein L9 1.5121
RPL23A ribosomal protein L23a 1.51123
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 1.5093
SOX2 SRY (sex determining region Y)-box 2 1.50756
ECE1 endothelin converting enzyme 1 1.50719
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 1.50598
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 1.50528
ATF6 activating transcription factor 6 1.50494
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 1.50325
SPRED2 sprouty-related, EVH1 domain containing 2 1.5027
IGFLR1 IGF-like family receptor 1 1.49837
DGKE diacylglycerol kinase, epsilon 64kDa 1.49503
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 1.4946
AP5S1 adaptor-related protein complex 5, sigma 1 subunit 1.48485
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 1.48413
GRB2 growth factor receptor-bound protein 2 1.48274
RNF130 ring finger protein 130 1.48188
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.48145
FZD7 frizzled class receptor 7 1.47783
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 1.47572
HMGB1 high mobility group box 1 1.47506
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.47492
CACYBP calcyclin binding protein 1.47463
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) 1.47363
MBOAT7 membrane bound O-acyltransferase domain containing 7 1.46991
NRBP1 nuclear receptor binding protein 1 1.46716
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.467
RNF40 ring finger protein 40, E3 ubiquitin protein ligase 1.46563
TP53BP2 tumor protein p53 binding protein 2 1.46499
TLE4 transducin-like enhancer of split 4 1.46432
SURF1 surfeit 1 1.464
UBFD1 ubiquitin family domain containing 1 1.46388
KIF26B kinesin family member 26B 1.46386
LRRC49 leucine rich repeat containing 49 1.4607
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 1.46035
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 1.45764
C1ORF35 chromosome 1 open reading frame 35 1.45729
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 1.45571
SRRM1 serine/arginine repetitive matrix 1 1.45129
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 1.45109
FTH1 ferritin, heavy polypeptide 1 1.45035
CLTA clathrin, light chain A 1.44946
QSOX1 quiescin Q6 sulfhydryl oxidase 1 1.44941
SAV1 salvador family WW domain containing protein 1 1.44936
STK38L serine/threonine kinase 38 like 1.44906
PPP1R10 protein phosphatase 1, regulatory subunit 10 1.44836
DOT1L DOT1-like histone H3K79 methyltransferase 1.44696
NOSIP nitric oxide synthase interacting protein 1.44604
IDE insulin-degrading enzyme 1.44292
KLK10 kallikrein-related peptidase 10 1.44013
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 1.43989
RPS16 ribosomal protein S16 1.43962
C17ORF59 chromosome 17 open reading frame 59 1.43945
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 1.43759
TBL2 transducin (beta)-like 2 1.4367
PRIM2 primase, DNA, polypeptide 2 (58kDa) 1.43247
TUBA3C tubulin, alpha 3c 1.43071
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1 1.42864
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) 1.42845
WBSCR22 Williams Beuren syndrome chromosome region 22 1.42834
RPS18 ribosomal protein S18 1.42679
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 1.42448
GON4L gon-4-like (C. elegans) 1.42443
GRK6 G protein-coupled receptor kinase 6 1.42441
EFTUD1 elongation factor Tu GTP binding domain containing 1 1.4193
RPL6 ribosomal protein L6 1.4182
SH2D2A SH2 domain containing 2A 1.41725
ADAR adenosine deaminase, RNA-specific 1.41359
HAX1 HCLS1 associated protein X-1 1.41093
ZNF143 zinc finger protein 143 1.41046
DIO2 deiodinase, iodothyronine, type II 1.40857
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 1.40775
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 1.40698
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 1.40698
CD300C CD300c molecule 1.40609
PNPLA2 patatin-like phospholipase domain containing 2 1.40252
EXTL3 exostosin-like glycosyltransferase 3 1.40067
SVIL supervillin 1.39931
RPL28 ribosomal protein L28 1.39906
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 1.3959
CLK2 CDC-like kinase 2 1.39569
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 1.395
ETV5 ets variant 5 1.39333
CBX1 chromobox homolog 1 1.39225
HARS histidyl-tRNA synthetase 1.39099
COL2A1 collagen, type II, alpha 1 1.38749
MX2 MX dynamin-like GTPase 2 1.387
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 1.38679
OLA1 Obg-like ATPase 1 1.38599
KDM5B lysine (K)-specific demethylase 5B 1.38593
LAPTM5 lysosomal protein transmembrane 5 1.38592
DARS2 aspartyl-tRNA synthetase 2, mitochondrial 1.38353
CCNT1 cyclin T1 1.38319
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.38247
ALKBH4 alkB, alkylation repair homolog 4 (E. coli) 1.38226
MOCS1 molybdenum cofactor synthesis 1 1.38165
DNAH3 dynein, axonemal, heavy chain 3 1.38092
TUFM Tu translation elongation factor, mitochondrial 1.37803
RGS19 regulator of G-protein signaling 19 1.37793
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa 1.37704
KPNB1 karyopherin (importin) beta 1 1.3756
PCDHA12 protocadherin alpha 12 1.37527
VGLL4 vestigial-like family member 4 1.37493
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle 1.37492
ELK1 ELK1, member of ETS oncogene family 1.37185
NAAA N-acylethanolamine acid amidase 1.37
ZNF43 zinc finger protein 43 1.36943
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) 1.36484
MYO7A myosin VIIA 1.36475
CPSF3L cleavage and polyadenylation specific factor 3-like 1.36287
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa 1.36161
TWF2 twinfilin actin binding protein 2 1.35638
ZBTB43 zinc finger and BTB domain containing 43 1.35511
NAP1L1 nucleosome assembly protein 1-like 1 1.35497
C1ORF68 chromosome 1 open reading frame 68 1.35062
BTBD1 BTB (POZ) domain containing 1 1.35018
ASIC1 acid sensing (proton gated) ion channel 1 1.34873
PRKCSH protein kinase C substrate 80K-H 1.34798
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) 1.34332
FGL1 fibrinogen-like 1 1.343
CCNG1 cyclin G1 1.33817
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 1.3364
IFFO1 intermediate filament family orphan 1 1.3358
FAM193A family with sequence similarity 193, member A 1.33523
RPL36 ribosomal protein L36 1.33337
BMI1 BMI1 proto-oncogene, polycomb ring finger 1.32984
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor 1.32937
SF3A3 splicing factor 3a, subunit 3, 60kDa 1.32697
UBE3A ubiquitin protein ligase E3A 1.32676

decreased expression

Symbol Name Standardized Value
HBZ hemoglobin, zeta -3.4907
CA4 carbonic anhydrase IV -3.33492
PODXL podocalyxin-like -3.28062
LGI1 leucine-rich, glioma inactivated 1 -3.075
HBG2 hemoglobin, gamma G -2.9091
AMBP alpha-1-microglobulin/bikunin precursor -2.76359
AGR2 anterior gradient 2 -2.73056
S100P S100 calcium binding protein P -2.67142
SEPHS2 selenophosphate synthetase 2 -2.63653
HSDL2 hydroxysteroid dehydrogenase like 2 -2.62517
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 -2.61717
ALX1 ALX homeobox 1 -2.61454
COBLL1 cordon-bleu WH2 repeat protein-like 1 -2.61076
PNN pinin, desmosome associated protein -2.5521
STARD8 StAR-related lipid transfer (START) domain containing 8 -2.53625
FAM149A family with sequence similarity 149, member A -2.53494
TRAM2 translocation associated membrane protein 2 -2.49513
PTPRO protein tyrosine phosphatase, receptor type, O -2.47933
KNG1 kininogen 1 -2.44934
IQCK IQ motif containing K -2.4166
USP25 ubiquitin specific peptidase 25 -2.4157
GSTM5 glutathione S-transferase mu 5 -2.41121
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase -2.40987
AKAP11 A kinase (PRKA) anchor protein 11 -2.38946
COMT catechol-O-methyltransferase -2.3807
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A -2.36291
GPRC5B G protein-coupled receptor, class C, group 5, member B -2.34922
DESI2 desumoylating isopeptidase 2 -2.34921
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 -2.3252
CALB1 calbindin 1, 28kDa -2.31917
AIM1 absent in melanoma 1 -2.3011
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 -2.30046
S100A14 S100 calcium binding protein A14 -2.29523
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 -2.26253
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase -2.25032
C7ORF49 chromosome 7 open reading frame 49 -2.24172
FGFR4 fibroblast growth factor receptor 4 -2.2341
FXYD3 FXYD domain containing ion transport regulator 3 -2.22925
GLS glutaminase -2.22667
DEFB1 defensin, beta 1 -2.22386
LUC7L2 LUC7-like 2 (S. cerevisiae) -2.22383
AFP alpha-fetoprotein -2.20753
AMD1 adenosylmethionine decarboxylase 1 -2.18278
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -2.18088
PREPL prolyl endopeptidase-like -2.16146
CLDN10 claudin 10 -2.16135
XBP1 X-box binding protein 1 -2.14361
CALCOCO1 calcium binding and coiled-coil domain 1 -2.13829
FZD4 frizzled class receptor 4 -2.13551
SCAPER S-phase cyclin A-associated protein in the ER -2.1302
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) -2.12918
UPK3A uroplakin 3A -2.11822
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F -2.11551
DPP4 dipeptidyl-peptidase 4 -2.11397
YTHDC1 YTH domain containing 1 -2.10633
RAB11FIP2 RAB11 family interacting protein 2 (class I) -2.09201
FBXO9 F-box protein 9 -2.08909
TUG1 taurine up-regulated 1 (non-protein coding) -2.08304
AMIGO2 adhesion molecule with Ig-like domain 2 -2.07321
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) -2.05628
TRAK1 trafficking protein, kinesin binding 1 -2.05567
ACTN4 actinin, alpha 4 -2.05496
KLHL35 kelch-like family member 35 -2.04622
MAP4 microtubule-associated protein 4 -2.04052
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -2.0385
NIP7 NIP7, nucleolar pre-rRNA processing protein -2.0273
NCOA3 nuclear receptor coactivator 3 -2.02561
MKRN1 makorin ring finger protein 1 -2.01477
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.01124
S100PBP S100P binding protein -2.00885
PTPRD protein tyrosine phosphatase, receptor type, D -2.00756
HGD homogentisate 1,2-dioxygenase -2.00492
METTL21B methyltransferase like 21B -1.9995
SPATA2 spermatogenesis associated 2 -1.9917
MAGED2 melanoma antigen family D2 -1.98838
SCFD1 sec1 family domain containing 1 -1.98514
VGLL1 vestigial-like family member 1 -1.98361
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) -1.97555
YAP1 Yes-associated protein 1 -1.97457
WIPF2 WAS/WASL interacting protein family, member 2 -1.97154
FABP1 fatty acid binding protein 1, liver -1.961
LAMB2 laminin, beta 2 (laminin S) -1.95043
HMGN3 high mobility group nucleosomal binding domain 3 -1.94915
SHANK2 SH3 and multiple ankyrin repeat domains 2 -1.94502
EMC2 ER membrane protein complex subunit 2 -1.94317
ZNF266 zinc finger protein 266 -1.94238
GK glycerol kinase -1.93926
TOM1L1 target of myb1 (chicken)-like 1 -1.93564
PSEN1 presenilin 1 -1.93398
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 -1.92856
PGPEP1 pyroglutamyl-peptidase I -1.92108
SMO smoothened, frizzled class receptor -1.91498
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 -1.91259
HBA1 hemoglobin, alpha 1 -1.91104
TYRO3 TYRO3 protein tyrosine kinase -1.90937
NEK3 NIMA-related kinase 3 -1.90722
PMS2P1 postmeiotic segregation increased 2 pseudogene 1 -1.90254
TMPRSS2 transmembrane protease, serine 2 -1.90042
HBA2 hemoglobin, alpha 2 -1.89771
LMBRD1 LMBR1 domain containing 1 -1.89707
ZNF419 zinc finger protein 419 -1.89592
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase -1.8863
TRPM3 transient receptor potential cation channel, subfamily M, member 3 -1.88267
SNX5 sorting nexin 5 -1.88262
ERBB4 erb-b2 receptor tyrosine kinase 4 -1.87849
TJP1 tight junction protein 1 -1.87769
PLCL1 phospholipase C-like 1 -1.87767
AKAP8 A kinase (PRKA) anchor protein 8 -1.87753
EIF5 eukaryotic translation initiation factor 5 -1.87566
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) -1.86889
MFN1 mitofusin 1 -1.86421
BRD2 bromodomain containing 2 -1.85702
DAAM2 dishevelled associated activator of morphogenesis 2 -1.84815
GYPA glycophorin A (MNS blood group) -1.84679
WWOX WW domain containing oxidoreductase -1.84302
RXRB retinoid X receptor, beta -1.83957
VDAC3 voltage-dependent anion channel 3 -1.83152
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein -1.82817
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) -1.82054
AFTPH aftiphilin -1.81885
TSEN2 TSEN2 tRNA splicing endonuclease subunit -1.81867
CALCA calcitonin-related polypeptide alpha -1.81809
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase -1.81464
KDR kinase insert domain receptor -1.80704
LAMA5 laminin, alpha 5 -1.80473
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) -1.78201
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans) -1.78139
ACAA1 acetyl-CoA acyltransferase 1 -1.78099
ALAS2 5'-aminolevulinate synthase 2 -1.78041
PPARG peroxisome proliferator-activated receptor gamma -1.77903
L1CAM L1 cell adhesion molecule -1.77002
EGFL6 EGF-like-domain, multiple 6 -1.76825
TSPAN15 tetraspanin 15 -1.76383
ERBB3 erb-b2 receptor tyrosine kinase 3 -1.76012
STX5 syntaxin 5 -1.76011
SEPT7 septin 7 -1.75596
ADORA2A adenosine A2a receptor -1.74888
TPPP3 tubulin polymerization-promoting protein family member 3 -1.74761
ERCC5 excision repair cross-complementation group 5 -1.74396
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 -1.74245
APOM apolipoprotein M -1.73821
PFKL phosphofructokinase, liver -1.73549
HIPK2 homeodomain interacting protein kinase 2 -1.73401
TMEM30A transmembrane protein 30A -1.72903
GALC galactosylceramidase -1.72212
HHEX hematopoietically expressed homeobox -1.71404
OLFML2A olfactomedin-like 2A -1.71205
COA3 cytochrome c oxidase assembly factor 3 -1.71039
EZR ezrin -1.70872
PDLIM2 PDZ and LIM domain 2 (mystique) -1.70565
TFCP2L1 transcription factor CP2-like 1 -1.70494
GSTK1 glutathione S-transferase kappa 1 -1.70062
DDN dendrin -1.69966
WDFY3 WD repeat and FYVE domain containing 3 -1.69471
FECH ferrochelatase -1.69333
GTF2H5 general transcription factor IIH, polypeptide 5 -1.68103
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -1.67875
BCL2L1 BCL2-like 1 -1.6715
SIN3B SIN3 transcription regulator family member B -1.66955
SFPQ splicing factor proline/glutamine-rich -1.66491
ALB albumin -1.66353
GSTM3 glutathione S-transferase mu 3 (brain) -1.66241
ZDHHC7 zinc finger, DHHC-type containing 7 -1.66144
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 -1.66053
FAM102A family with sequence similarity 102, member A -1.66005
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 -1.65278
DET1 de-etiolated homolog 1 (Arabidopsis) -1.6515
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5 -1.64962
ERLIN2 ER lipid raft associated 2 -1.6482
IQGAP1 IQ motif containing GTPase activating protein 1 -1.64612
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) -1.64606
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -1.64168
ANXA11 annexin A11 -1.63947
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) -1.63939
RAP2A RAP2A, member of RAS oncogene family -1.62616
MID1 midline 1 -1.61802
CD248 CD248 molecule, endosialin -1.61617
SUCLG1 succinate-CoA ligase, alpha subunit -1.61312
ACSS3 acyl-CoA synthetase short-chain family member 3 -1.61223
CCBL1 cysteine conjugate-beta lyase, cytoplasmic -1.60962
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) -1.60923
KIF15 kinesin family member 15 -1.60919
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -1.60722
PCYT2 phosphate cytidylyltransferase 2, ethanolamine -1.60574
RAD17 RAD17 homolog (S. pombe) -1.60143
DTYMK deoxythymidylate kinase (thymidylate kinase) -1.60061
DCP2 decapping mRNA 2 -1.5965
REPS2 RALBP1 associated Eps domain containing 2 -1.5926
RHOD ras homolog family member D -1.58967
SGK2 serum/glucocorticoid regulated kinase 2 -1.58836
PDIA6 protein disulfide isomerase family A, member 6 -1.58022
DMXL1 Dmx-like 1 -1.57869
IVD isovaleryl-CoA dehydrogenase -1.57607
ARRB1 arrestin, beta 1 -1.57417
PICALM phosphatidylinositol binding clathrin assembly protein -1.57032
ACAD8 acyl-CoA dehydrogenase family, member 8 -1.56969
UPK1A uroplakin 1A -1.56928
CES2 carboxylesterase 2 -1.56837
FERMT2 fermitin family member 2 -1.56712
ELOVL1 ELOVL fatty acid elongase 1 -1.5665
DHCR24 24-dehydrocholesterol reductase -1.56478
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD) -1.5647
ZNF211 zinc finger protein 211 -1.56344
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) -1.56005
KRT8 keratin 8, type II -1.56001
MEF2A myocyte enhancer factor 2A -1.55176
KIRREL kin of IRRE like (Drosophila) -1.551
FHOD1 formin homology 2 domain containing 1 -1.54351
CALCRL calcitonin receptor-like -1.5424
SMAD1 SMAD family member 1 -1.54213
ACYP1 acylphosphatase 1, erythrocyte (common) type -1.53942
ETFDH electron-transferring-flavoprotein dehydrogenase -1.53931
EXOC7 exocyst complex component 7 -1.53564
RELN reelin -1.53553
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 -1.53538
CSHL1 chorionic somatomammotropin hormone-like 1 -1.53492
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle -1.53394
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -1.53298
PRPS2 phosphoribosyl pyrophosphate synthetase 2 -1.53009
C7ORF26 chromosome 7 open reading frame 26 -1.52895
ELF5 E74-like factor 5 (ets domain transcription factor) -1.52885
PHACTR2 phosphatase and actin regulator 2 -1.52439
UBE2A ubiquitin-conjugating enzyme E2A -1.5238
GSTM2 glutathione S-transferase mu 2 (muscle) -1.52362
ATP7A ATPase, Cu++ transporting, alpha polypeptide -1.52168
MSMO1 methylsterol monooxygenase 1 -1.5216
BBS1 Bardet-Biedl syndrome 1 -1.51917
AIF1 allograft inflammatory factor 1 -1.51838
REN renin -1.51754
GATAD1 GATA zinc finger domain containing 1 -1.51608
CAB39 calcium binding protein 39 -1.51418
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) -1.51017
UXS1 UDP-glucuronate decarboxylase 1 -1.50943
PRR5 proline rich 5 (renal) -1.50574
TPM4 tropomyosin 4 -1.50512
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa -1.50227
BCAT1 branched chain amino-acid transaminase 1, cytosolic -1.49991
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila) -1.49903
PTGER3 prostaglandin E receptor 3 (subtype EP3) -1.49336
ADAM12 ADAM metallopeptidase domain 12 -1.49301
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -1.49216
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -1.49215
DHRS2 dehydrogenase/reductase (SDR family) member 2 -1.49141
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) -1.4913
GYPB glycophorin B (MNS blood group) -1.49008
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -1.48775
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 -1.48409
RNF144A ring finger protein 144A -1.48202
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -1.48196
HIBCH 3-hydroxyisobutyryl-CoA hydrolase -1.47904
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -1.47861
NUBPL nucleotide binding protein-like -1.47784
MCPH1 microcephalin 1 -1.4721
COL4A5 collagen, type IV, alpha 5 -1.47001
GAL3ST1 galactose-3-O-sulfotransferase 1 -1.46836
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa -1.46835
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) -1.46625
UPK1B uroplakin 1B -1.46534
DHRS1 dehydrogenase/reductase (SDR family) member 1 -1.46494
SUOX sulfite oxidase -1.46126
CDC25B cell division cycle 25B -1.45941
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 -1.45867
HIF3A hypoxia inducible factor 3, alpha subunit -1.45832
TPST2 tyrosylprotein sulfotransferase 2 -1.45801
FXYD2 FXYD domain containing ion transport regulator 2 -1.45582
CC2D2B coiled-coil and C2 domain containing 2B -1.45572
ELMO3 engulfment and cell motility 3 -1.45368
TMEM115 transmembrane protein 115 -1.45355
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -1.45151
C14ORF159 chromosome 14 open reading frame 159 -1.45146
DNPEP aspartyl aminopeptidase -1.45021
PIEZO1 piezo-type mechanosensitive ion channel component 1 -1.44518
EDNRB endothelin receptor type B -1.44457
PPAP2A phosphatidic acid phosphatase type 2A -1.44426
LIMK2 LIM domain kinase 2 -1.44373
PGRMC2 progesterone receptor membrane component 2 -1.43885
ADD1 adducin 1 (alpha) -1.43884
PPIA peptidylprolyl isomerase A (cyclophilin A) -1.43596
PEX3 peroxisomal biogenesis factor 3 -1.43147
BLCAP bladder cancer associated protein -1.43052
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) -1.42996
PPP1R3C protein phosphatase 1, regulatory subunit 3C -1.42949
DNAAF5 dynein, axonemal, assembly factor 5 -1.42895
TGOLN2 trans-golgi network protein 2 -1.42601
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -1.4257
MLF1 myeloid leukemia factor 1 -1.42478
MIOS missing oocyte, meiosis regulator, homolog (Drosophila) -1.42446
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -1.42186
RNF10 ring finger protein 10 -1.417
PTPN21 protein tyrosine phosphatase, non-receptor type 21 -1.41082
TM9SF3 transmembrane 9 superfamily member 3 -1.40865
CNOT4 CCR4-NOT transcription complex, subunit 4 -1.40764
HBBP1 hemoglobin, beta pseudogene 1 -1.40701
AK2 adenylate kinase 2 -1.40687
NCAPG2 non-SMC condensin II complex, subunit G2 -1.40683
ZNF544 zinc finger protein 544 -1.40667
AACS acetoacetyl-CoA synthetase -1.40381
ATF4 activating transcription factor 4 -1.40266
WFS1 Wolfram syndrome 1 (wolframin) -1.40182
NME6 NME/NM23 nucleoside diphosphate kinase 6 -1.40013
Funding