Nephrogenic Syndrome Of Inappropriate Antidiuresis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Nephrogenic syndrome of inappropriate antidiuresis (NSIAD) is a rare genetic disorder of water balance, closely resembling the far more frequent syndrome of inappropriate antidiuretic secretion (SIAD), and characterized by euvolemic hypotonic hyponatremia due to impaired free water excretion and undetectable or low plasma arginine vasopressin (AVP) levels. (Orphanet Rare Disease Ontology, Orphanet_93606)
External Link https://www.disgenet.org/browser/0/1/0/C1845202
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Genes

14 genes associated with the disease Nephrogenic Syndrome Of Inappropriate Antidiuresis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACKR3 atypical chemokine receptor 3
ADRA1A adrenoceptor alpha 1A
ADRA2B adrenoceptor alpha 2B
AQP2 aquaporin 2 (collecting duct)
AVP arginine vasopressin
AVPR2 arginine vasopressin receptor 2
BRS3 bombesin-like receptor 3
CXCR6 chemokine (C-X-C motif) receptor 6
EDNRA endothelin receptor type A
GPR42 G protein-coupled receptor 42 (gene/pseudogene)
LPAR2 lysophosphatidic acid receptor 2
MSN moesin
SSTR4 somatostatin receptor 4
VWF von Willebrand factor