Nephrogenic systemic fibrosis (NSF) is a rare systemic fibrosing condition observed in renally impaired patients and characterized by a hardening and thickening of the skin with fibrotic plaques or papules, pruritus, joint pain and stiffness, muscle weakness, limitation of range of motion, and yellowed eyes. It is generally associated with administration of gadolinium-based magnetic resonance imaging contrast agents (GBCA) in patients with kidney disease. (Orphanet Rare Disease Ontology, Orphanet_137617)
12 genes associated with the disease Nephrogenic Systemic Fibrosis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
