Nephrolithiasis_Kidney_GSE10162 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE10162
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Genes

600 genes differentially expressed during Nephrolithiasis_Kidney_GSE10162 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
ZFP36 ZFP36 ring finger protein 4.68219
TREH trehalase (brush-border membrane glycoprotein) 4.43812
SLC25A46 solute carrier family 25, member 46 4.13812
DEPDC1B DEP domain containing 1B 3.65731
HBEGF heparin-binding EGF-like growth factor 3.65455
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 3.47985
UBR4 ubiquitin protein ligase E3 component n-recognin 4 3.40927
ADAT2 adenosine deaminase, tRNA-specific 2 3.07652
TM6SF2 transmembrane 6 superfamily member 2 2.93882
FAM114A2 family with sequence similarity 114, member A2 2.77022
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase 2.66977
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 2.62567
TUFT1 tuftelin 1 2.61724
TMEM39A transmembrane protein 39A 2.60586
FUOM fucose mutarotase 2.55332
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 2.52903
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 2.52814
SQLE squalene epoxidase 2.4612
TMPRSS2 transmembrane protease, serine 2 2.44901
PIGF phosphatidylinositol glycan anchor biosynthesis, class F 2.43912
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial 2.39921
CNDP1 carnosine dipeptidase 1 (metallopeptidase M20 family) 2.32152
SDC4 syndecan 4 2.316
MLXIPL MLX interacting protein-like 2.27571
NUAK2 NUAK family, SNF1-like kinase, 2 2.25648
CLIC4 chloride intracellular channel 4 2.25521
CLU clusterin 2.24288
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 2.24076
TMBIM4 transmembrane BAX inhibitor motif containing 4 2.23197
MEP1B meprin A, beta 2.22175
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 2.2029
RHBG Rh family, B glycoprotein (gene/pseudogene) 2.17552
CHID1 chitinase domain containing 1 2.1629
PNPLA6 patatin-like phospholipase domain containing 6 2.16252
DUSP1 dual specificity phosphatase 1 2.15873
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 2.15788
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 2.13107
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 2.11934
MRPL44 mitochondrial ribosomal protein L44 2.11623
C4ORF27 chromosome 4 open reading frame 27 2.10484
INTS9 integrator complex subunit 9 2.06531
OSBPL8 oxysterol binding protein-like 8 2.03005
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 2.02948
RBBP4 retinoblastoma binding protein 4 1.99584
ACOT9 acyl-CoA thioesterase 9 1.98921
TTI1 TELO2 interacting protein 1 1.92157
AGTR1 angiotensin II receptor, type 1 1.90761
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 1.90692
COX18 COX18 cytochrome c oxidase assembly factor 1.88432
NDRG3 NDRG family member 3 1.87147
APOM apolipoprotein M 1.87015
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) 1.85695
FTCD formimidoyltransferase cyclodeaminase 1.83399
CLSTN1 calsyntenin 1 1.82789
AADAT aminoadipate aminotransferase 1.82252
PAK1IP1 PAK1 interacting protein 1 1.81023
WDR6 WD repeat domain 6 1.79924
CNOT6 CCR4-NOT transcription complex, subunit 6 1.78931
ENPEP glutamyl aminopeptidase (aminopeptidase A) 1.78276
ERGIC3 ERGIC and golgi 3 1.77488
JTB jumping translocation breakpoint 1.77314
SCAMP2 secretory carrier membrane protein 2 1.77234
RNF26 ring finger protein 26 1.77197
GNA14 guanine nucleotide binding protein (G protein), alpha 14 1.76813
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 1.76065
GPC4 glypican 4 1.73272
TTC13 tetratricopeptide repeat domain 13 1.7185
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 1.70591
RDH10 retinol dehydrogenase 10 (all-trans) 1.69115
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 1.68248
PES1 pescadillo ribosomal biogenesis factor 1 1.66793
CDK5RAP1 CDK5 regulatory subunit associated protein 1 1.64042
CROCC ciliary rootlet coiled-coil, rootletin 1.63956
AP1S3 adaptor-related protein complex 1, sigma 3 subunit 1.6369
CBX6 chromobox homolog 6 1.63237
SAMD9L sterile alpha motif domain containing 9-like 1.6125
BLVRA biliverdin reductase A 1.61004
SUSD2 sushi domain containing 2 1.57452
DPY19L3 dpy-19-like 3 (C. elegans) 1.57432
UMOD uromodulin 1.56603
EGR1 early growth response 1 1.56231
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 1.55071
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae) 1.548
MOGAT1 monoacylglycerol O-acyltransferase 1 1.52216
HDAC1 histone deacetylase 1 1.51833
NHP2 NHP2 ribonucleoprotein 1.51265
RARS2 arginyl-tRNA synthetase 2, mitochondrial 1.49529
TMEM25 transmembrane protein 25 1.49458
ETHE1 ethylmalonic encephalopathy 1 1.48411
ACSL5 acyl-CoA synthetase long-chain family member 5 1.48087
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 1.47396
COL4A4 collagen, type IV, alpha 4 1.46116
SERF2 small EDRK-rich factor 2 1.45073
FBXO36 F-box protein 36 1.43802
BSDC1 BSD domain containing 1 1.43729
UBIAD1 UbiA prenyltransferase domain containing 1 1.43297
LAP3 leucine aminopeptidase 3 1.4286
CLCN3 chloride channel, voltage-sensitive 3 1.42739
THUMPD2 THUMP domain containing 2 1.42431
GRAMD1B GRAM domain containing 1B 1.41951
SLC35B3 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3 1.40694
JUN jun proto-oncogene 1.40117
FGD5 FYVE, RhoGEF and PH domain containing 5 1.40055
PIGR polymeric immunoglobulin receptor 1.38525
TMIGD1 transmembrane and immunoglobulin domain containing 1 1.37747
SEC16A SEC16 homolog A (S. cerevisiae) 1.37315
RPA1 replication protein A1, 70kDa 1.3726
ERRFI1 ERBB receptor feedback inhibitor 1 1.3712
IGF1R insulin-like growth factor 1 receptor 1.37076
SLC26A4 solute carrier family 26 (anion exchanger), member 4 1.36497
THBS1 thrombospondin 1 1.36132
IQCF1 IQ motif containing F1 1.35994
TRIM41 tripartite motif containing 41 1.35974
RPL15 ribosomal protein L15 1.35807
ZC3H11A zinc finger CCCH-type containing 11A 1.35457
EHMT1 euchromatic histone-lysine N-methyltransferase 1 1.34575
PRMT1 protein arginine methyltransferase 1 1.34572
UBC ubiquitin C 1.34464
CMIP c-Maf inducing protein 1.34087
CD9 CD9 molecule 1.34041
VASP vasodilator-stimulated phosphoprotein 1.3369
CHD1L chromodomain helicase DNA binding protein 1-like 1.33678
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 1.33673
SCRN3 secernin 3 1.33553
MED28 mediator complex subunit 28 1.33424
CACHD1 cache domain containing 1 1.33367
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) 1.32041
RRP36 ribosomal RNA processing 36 homolog (S. cerevisiae) 1.31582
GPD1L glycerol-3-phosphate dehydrogenase 1-like 1.30941
CSRP1 cysteine and glycine-rich protein 1 1.30034
CADM1 cell adhesion molecule 1 1.29619
H1F0 H1 histone family, member 0 1.28788
SNAP47 synaptosomal-associated protein, 47kDa 1.28419
PHAX phosphorylated adaptor for RNA export 1.28219
TSN translin 1.27928
MARK3 MAP/microtubule affinity-regulating kinase 3 1.2768
DENND5A DENN/MADD domain containing 5A 1.27668
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 1.27518
CALB1 calbindin 1, 28kDa 1.27463
IGSF11 immunoglobulin superfamily, member 11 1.2741
SUCNR1 succinate receptor 1 1.26793
PLXNB1 plexin B1 1.26783
DALRD3 DALR anticodon binding domain containing 3 1.26103
PIAS1 protein inhibitor of activated STAT, 1 1.25691
BDH1 3-hydroxybutyrate dehydrogenase, type 1 1.25514
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.25475
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1.25262
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.25192
NIPSNAP1 nipsnap homolog 1 (C. elegans) 1.24989
GADD45G growth arrest and DNA-damage-inducible, gamma 1.24959
PPP4R2 protein phosphatase 4, regulatory subunit 2 1.24905
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 1.24343
NUDT8 nudix (nucleoside diphosphate linked moiety X)-type motif 8 1.2383
INPP5B inositol polyphosphate-5-phosphatase, 75kDa 1.23696
CC2D1A coiled-coil and C2 domain containing 1A 1.23111
EPC2 enhancer of polycomb homolog 2 (Drosophila) 1.22623
SPINT2 serine peptidase inhibitor, Kunitz type, 2 1.21363
CSF1R colony stimulating factor 1 receptor 1.2095
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae) 1.20917
PARL presenilin associated, rhomboid-like 1.19642
SEC23IP SEC23 interacting protein 1.1931
SRSF3 serine/arginine-rich splicing factor 3 1.1887
SPINK8 serine peptidase inhibitor, Kazal type 8 (putative) 1.18844
HDDC3 HD domain containing 3 1.17368
CAMLG calcium modulating ligand 1.1734
EMG1 EMG1 N1-specific pseudouridine methyltransferase 1.17329
CDR2 cerebellar degeneration-related protein 2, 62kDa 1.17158
LYZ lysozyme 1.1666
CCDC90B coiled-coil domain containing 90B 1.16569
LARP4B La ribonucleoprotein domain family, member 4B 1.16569
LITAF lipopolysaccharide-induced TNF factor 1.15878
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 1.15782
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 1.15671
PTPDC1 protein tyrosine phosphatase domain containing 1 1.1547
FAM129B family with sequence similarity 129, member B 1.15425
ZWILCH zwilch kinetochore protein 1.15383
TTC1 tetratricopeptide repeat domain 1 1.15312
TMEM185A transmembrane protein 185A 1.15246
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 1.15161
TRIM7 tripartite motif containing 7 1.14543
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 1.14386
ADRBK1 adrenergic, beta, receptor kinase 1 1.14015
TDG thymine-DNA glycosylase 1.12686
MKRN1 makorin ring finger protein 1 1.12374
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) 1.12347
CLCNKA chloride channel, voltage-sensitive Ka 1.12069
HAUS7 HAUS augmin-like complex, subunit 7 1.1178
LPIN1 lipin 1 1.11262
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2 1.11239
ORC3 origin recognition complex, subunit 3 1.11219
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 1.10323
SHMT1 serine hydroxymethyltransferase 1 (soluble) 1.10089
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 1.09778
AHCY adenosylhomocysteinase 1.09591
NUMA1 nuclear mitotic apparatus protein 1 1.08766
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 1.08359
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.08127
WNT5A wingless-type MMTV integration site family, member 5A 1.07875
COL1A1 collagen, type I, alpha 1 1.07707
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.0678
PFN1 profilin 1 1.06525
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 1.06027
AURKAIP1 aurora kinase A interacting protein 1 1.05754
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 1.05231
C18ORF32 chromosome 18 open reading frame 32 1.05061
L2HGDH L-2-hydroxyglutarate dehydrogenase 1.04648
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 1.04492
GDF15 growth differentiation factor 15 1.04321
CRYZL1 crystallin, zeta (quinone reductase)-like 1 1.03665
SMAD4 SMAD family member 4 1.03148
SF3B1 splicing factor 3b, subunit 1, 155kDa 1.03102
TLCD2 TLC domain containing 2 1.02645
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 1.02174
SLC38A6 solute carrier family 38, member 6 1.02151
CRYM crystallin, mu 1.02128
PVALB parvalbumin 1.01275
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 1.01232
TMEM147 transmembrane protein 147 1.009
IDI1 isopentenyl-diphosphate delta isomerase 1 1.0066
HIPK3 homeodomain interacting protein kinase 3 1.00649
MED30 mediator complex subunit 30 1.0008
MRPS30 mitochondrial ribosomal protein S30 1.00022
CLN3 ceroid-lipofuscinosis, neuronal 3 0.994696
HAAO 3-hydroxyanthranilate 3,4-dioxygenase 0.993777
PMPCB peptidase (mitochondrial processing) beta 0.99239
TSPAN5 tetraspanin 5 0.99193
CRTAP cartilage associated protein 0.980524
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 0.976643
ARID2 AT rich interactive domain 2 (ARID, RFX-like) 0.97629
ZNHIT2 zinc finger, HIT-type containing 2 0.974454
IDUA iduronidase, alpha-L- 0.974348
KIAA2018 KIAA2018 0.973419
MTMR10 myotubularin related protein 10 0.964888
NGRN neugrin, neurite outgrowth associated 0.964646
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like 0.964241
PRR5 proline rich 5 (renal) 0.957229
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 0.953178
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 0.946677
GOLGA5 golgin A5 0.941529
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.938771
COPB1 coatomer protein complex, subunit beta 1 0.937685
PHLDA3 pleckstrin homology-like domain, family A, member 3 0.935264
RHOC ras homolog family member C 0.934427
BOC BOC cell adhesion associated, oncogene regulated 0.932579
FCF1 FCF1 rRNA-processing protein 0.930828
MACROD1 MACRO domain containing 1 0.924967
TMOD1 tropomodulin 1 0.921565
CLDN7 claudin 7 0.918562
FAM43A family with sequence similarity 43, member A 0.913071
HTRA1 HtrA serine peptidase 1 0.912987
IYD iodotyrosine deiodinase 0.91222
RFC5 replication factor C (activator 1) 5, 36.5kDa 0.909889
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 0.909039
WDFY2 WD repeat and FYVE domain containing 2 0.908639
SPNS2 spinster homolog 2 (Drosophila) 0.90852
CCBL1 cysteine conjugate-beta lyase, cytoplasmic 0.907996
MAP3K4 mitogen-activated protein kinase kinase kinase 4 0.906566
CCNDBP1 cyclin D-type binding-protein 1 0.903132
SNX7 sorting nexin 7 0.903083
ARHGAP5 Rho GTPase activating protein 5 0.901651
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.899054
QPRT quinolinate phosphoribosyltransferase 0.895619
SLC7A13 solute carrier family 7 (anionic amino acid transporter), member 13 0.894779
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 0.894103
GLOD4 glyoxalase domain containing 4 0.892013
TCTEX1D2 Tctex1 domain containing 2 0.891858
NBR1 neighbor of BRCA1 gene 1 0.889251
ITFG3 integrin alpha FG-GAP repeat containing 3 0.889158
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 0.888403
MTSS1 metastasis suppressor 1 0.887601
NONO non-POU domain containing, octamer-binding 0.886168
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD) 0.883488
ROGDI rogdi homolog (Drosophila) 0.883338
TM4SF1 transmembrane 4 L six family member 1 0.883331
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa 0.883327
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 0.882112
PIM3 Pim-3 proto-oncogene, serine/threonine kinase 0.880546
HDAC6 histone deacetylase 6 0.879748
PHB prohibitin 0.876736
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.875621
TRIM28 tripartite motif containing 28 0.874086
VKORC1 vitamin K epoxide reductase complex, subunit 1 0.872364
TOX3 TOX high mobility group box family member 3 0.868323
TNS1 tensin 1 0.867786
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.866342
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 0.862994
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.860423
TRIP6 thyroid hormone receptor interactor 6 0.858122
CHSY1 chondroitin sulfate synthase 1 0.85794
SMAGP small cell adhesion glycoprotein 0.849006
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.847567
TESC tescalcin 0.847299
CYR61 cysteine-rich, angiogenic inducer, 61 0.846657
B3GAT2 beta-1,3-glucuronyltransferase 2 0.843825
CSRP2 cysteine and glycine-rich protein 2 0.843306
MRPL14 mitochondrial ribosomal protein L14 0.841
MTMR4 myotubularin related protein 4 0.84076
VPS37A vacuolar protein sorting 37 homolog A (S. cerevisiae) 0.836049
BOD1 biorientation of chromosomes in cell division 1 0.835667
IFITM2 interferon induced transmembrane protein 2 0.833854

decreased expression

Symbol Name Standardized Value
HEXA hexosaminidase A (alpha polypeptide) -5.33397
PAM peptidylglycine alpha-amidating monooxygenase -4.77301
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -4.21045
GUK1 guanylate kinase 1 -3.65479
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) -3.35082
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase -3.35
TSPO translocator protein (18kDa) -3.21526
ACAA2 acetyl-CoA acyltransferase 2 -3.20204
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22 -3.16282
TRPV4 transient receptor potential cation channel, subfamily V, member 4 -3.09572
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -3.08307
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -3.03644
PLEKHA7 pleckstrin homology domain containing, family A member 7 -2.99618
HLF hepatic leukemia factor -2.98819
RAP1B RAP1B, member of RAS oncogene family -2.97936
C8G complement component 8, gamma polypeptide -2.97527
PXMP4 peroxisomal membrane protein 4, 24kDa -2.97334
ZNF322 zinc finger protein 322 -2.84233
APRT adenine phosphoribosyltransferase -2.76601
USP38 ubiquitin specific peptidase 38 -2.72233
RRAGD Ras-related GTP binding D -2.66467
IARS isoleucyl-tRNA synthetase -2.63254
CDH2 cadherin 2, type 1, N-cadherin (neuronal) -2.56914
SPC25 SPC25, NDC80 kinetochore complex component -2.5616
GLO1 glyoxalase I -2.50354
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) -2.49776
DCST2 DC-STAMP domain containing 2 -2.43774
CXCL16 chemokine (C-X-C motif) ligand 16 -2.3936
CDK4 cyclin-dependent kinase 4 -2.38779
DUSP23 dual specificity phosphatase 23 -2.3579
CLCN5 chloride channel, voltage-sensitive 5 -2.32375
KDM2B lysine (K)-specific demethylase 2B -2.3003
TARSL2 threonyl-tRNA synthetase-like 2 -2.26953
BEX4 brain expressed, X-linked 4 -2.25602
RNF145 ring finger protein 145 -2.20686
TST thiosulfate sulfurtransferase (rhodanese) -2.20105
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 -2.16851
PROM1 prominin 1 -2.12322
SLCO3A1 solute carrier organic anion transporter family, member 3A1 -2.11177
CREG1 cellular repressor of E1A-stimulated genes 1 -2.10424
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 -2.08812
SOWAHB sosondowah ankyrin repeat domain family member B -2.06605
MRPS33 mitochondrial ribosomal protein S33 -2.06244
BRAP BRCA1 associated protein -2.02803
TMEM252 transmembrane protein 252 -1.99068
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) -1.95456
PGPEP1 pyroglutamyl-peptidase I -1.94581
CA14 carbonic anhydrase XIV -1.94515
TGM1 transglutaminase 1 -1.91628
LRRC59 leucine rich repeat containing 59 -1.91284
VNN1 vanin 1 -1.90617
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 -1.8688
COL27A1 collagen, type XXVII, alpha 1 -1.84878
PSAP prosaposin -1.84132
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 -1.83545
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -1.83054
RAB22A RAB22A, member RAS oncogene family -1.81635
IRF8 interferon regulatory factor 8 -1.80293
TSPAN33 tetraspanin 33 -1.78301
NRIP1 nuclear receptor interacting protein 1 -1.7598
GHITM growth hormone inducible transmembrane protein -1.73875
DYNLT3 dynein, light chain, Tctex-type 3 -1.71689
LPL lipoprotein lipase -1.71488
MAN2A1 mannosidase, alpha, class 2A, member 1 -1.68022
UFSP2 UFM1-specific peptidase 2 -1.66579
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1 -1.65579
HOXA9 homeobox A9 -1.634
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 -1.61867
TMX1 thioredoxin-related transmembrane protein 1 -1.61361
DOCK5 dedicator of cytokinesis 5 -1.61049
CRIPT cysteine-rich PDZ-binding protein -1.60501
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -1.60354
ITGB1BP1 integrin beta 1 binding protein 1 -1.60337
MCOLN3 mucolipin 3 -1.60212
IGFBP3 insulin-like growth factor binding protein 3 -1.59766
C1ORF198 chromosome 1 open reading frame 198 -1.5924
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa -1.58822
AP1AR adaptor-related protein complex 1 associated regulatory protein -1.56603
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 -1.55892
TMEM82 transmembrane protein 82 -1.55422
MANBA mannosidase, beta A, lysosomal -1.55328
AADAC arylacetamide deacetylase -1.55316
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -1.55173
PBX3 pre-B-cell leukemia homeobox 3 -1.53853
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -1.53406
RNASE4 ribonuclease, RNase A family, 4 -1.53181
SLC22A23 solute carrier family 22, member 23 -1.51197
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha -1.4993
GJB1 gap junction protein, beta 1, 32kDa -1.4915
CTSH cathepsin H -1.48551
ADI1 acireductone dioxygenase 1 -1.47085
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 -1.45894
CHN2 chimerin 2 -1.45659
GC group-specific component (vitamin D binding protein) -1.45518
STX7 syntaxin 7 -1.42893
CAMK1 calcium/calmodulin-dependent protein kinase I -1.42829
NEURL1B neuralized E3 ubiquitin protein ligase 1B -1.42152
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 -1.41533
C9ORF72 chromosome 9 open reading frame 72 -1.4074
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa -1.37897
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -1.36669
ECI1 enoyl-CoA delta isomerase 1 -1.36542
RETSAT retinol saturase (all-trans-retinol 13,14-reductase) -1.36192
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 -1.35956
TIGD2 tigger transposable element derived 2 -1.3529
TGFBR3 transforming growth factor, beta receptor III -1.33892
ADM2 adrenomedullin 2 -1.32522
FAM91A1 family with sequence similarity 91, member A1 -1.32504
DPP7 dipeptidyl-peptidase 7 -1.32241
TMED6 transmembrane emp24 protein transport domain containing 6 -1.3181
FABP7 fatty acid binding protein 7, brain -1.31307
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -1.31301
MLX MLX, MAX dimerization protein -1.30407
PC pyruvate carboxylase -1.29077
PQLC1 PQ loop repeat containing 1 -1.28853
TMEM106A transmembrane protein 106A -1.27886
PER2 period circadian clock 2 -1.27856
MDK midkine (neurite growth-promoting factor 2) -1.27403
GLRX glutaredoxin (thioltransferase) -1.27179
TTR transthyretin -1.26858
RPIA ribose 5-phosphate isomerase A -1.2603
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal -1.25723
PLCXD2 phosphatidylinositol-specific phospholipase C, X domain containing 2 -1.24199
SLC6A19 solute carrier family 6 (neutral amino acid transporter), member 19 -1.23779
CCND1 cyclin D1 -1.2367
C9ORF152 chromosome 9 open reading frame 152 -1.23256
SLC35A5 solute carrier family 35, member A5 -1.22394
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 -1.21791
EDF1 endothelial differentiation-related factor 1 -1.21771
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 -1.20875
BHLHE40 basic helix-loop-helix family, member e40 -1.20124
WWTR1 WW domain containing transcription regulator 1 -1.19494
RRAGC Ras-related GTP binding C -1.18999
SC5D sterol-C5-desaturase -1.18395
NCOA3 nuclear receptor coactivator 3 -1.16244
UGT2B10 UDP glucuronosyltransferase 2 family, polypeptide B10 -1.15969
IGFALS insulin-like growth factor binding protein, acid labile subunit -1.15198
GMPPA GDP-mannose pyrophosphorylase A -1.14842
APOB apolipoprotein B -1.14767
HPD 4-hydroxyphenylpyruvate dioxygenase -1.14596
NBN nibrin -1.14394
HSDL1 hydroxysteroid dehydrogenase like 1 -1.14328
CDA cytidine deaminase -1.14325
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) -1.12808
LGALS1 lectin, galactoside-binding, soluble, 1 -1.11966
RAB11FIP5 RAB11 family interacting protein 5 (class I) -1.11954
IGFBP1 insulin-like growth factor binding protein 1 -1.11258
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) -1.10439
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -1.10197
ZFP36L2 ZFP36 ring finger protein-like 2 -1.0977
AXL AXL receptor tyrosine kinase -1.09213
C14ORF159 chromosome 14 open reading frame 159 -1.0912
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -1.08831
PHYHD1 phytanoyl-CoA dioxygenase domain containing 1 -1.07815
NR1D2 nuclear receptor subfamily 1, group D, member 2 -1.07195
DENND3 DENN/MADD domain containing 3 -1.07058
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -1.06522
CISD2 CDGSH iron sulfur domain 2 -1.06309
EXOSC5 exosome component 5 -1.06007
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -1.05753
PPP1R12C protein phosphatase 1, regulatory subunit 12C -1.05609
MMD monocyte to macrophage differentiation-associated -1.05419
GPR146 G protein-coupled receptor 146 -1.05387
FAM127C family with sequence similarity 127, member C -1.05321
LIPA lipase A, lysosomal acid, cholesterol esterase -1.05263
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 -1.05004
AMPD3 adenosine monophosphate deaminase 3 -1.04907
C16ORF58 chromosome 16 open reading frame 58 -1.04459
TRIP4 thyroid hormone receptor interactor 4 -1.04423
NRBP1 nuclear receptor binding protein 1 -1.03994
KDELC2 KDEL (Lys-Asp-Glu-Leu) containing 2 -1.02912
TSTD1 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 -1.02396
FAM132A family with sequence similarity 132, member A -1.02227
STARD4 StAR-related lipid transfer (START) domain containing 4 -1.02128
SERINC3 serine incorporator 3 -1.01976
COCH cochlin -1.01741
CREB3L2 cAMP responsive element binding protein 3-like 2 -1.01551
SWT1 SWT1 RNA endoribonuclease homolog (S. cerevisiae) -1.01203
SOX18 SRY (sex determining region Y)-box 18 -1.00799
LMTK2 lemur tyrosine kinase 2 -1.00749
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 -1.00678
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) -1.00234
ELAC2 elaC ribonuclease Z 2 -0.994117
GJB2 gap junction protein, beta 2, 26kDa -0.985455
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) -0.983186
ETV2 ets variant 2 -0.979226
CTSZ cathepsin Z -0.978613
CDC34 cell division cycle 34 -0.976195
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 -0.973565
CLIP4 CAP-GLY domain containing linker protein family, member 4 -0.972649
DHPS deoxyhypusine synthase -0.970766
RNF167 ring finger protein 167 -0.969998
COASY CoA synthase -0.968586
GLDC glycine dehydrogenase (decarboxylating) -0.964943
EIF3L eukaryotic translation initiation factor 3, subunit L -0.963957
STAB2 stabilin 2 -0.962242
PSAT1 phosphoserine aminotransferase 1 -0.961361
HSPA13 heat shock protein 70kDa family, member 13 -0.958188
RBM34 RNA binding motif protein 34 -0.957063
OAT ornithine aminotransferase -0.95675
MRPL34 mitochondrial ribosomal protein L34 -0.955452
EIF4E2 eukaryotic translation initiation factor 4E family member 2 -0.954969
TRIP10 thyroid hormone receptor interactor 10 -0.951954
ZNF267 zinc finger protein 267 -0.949847
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.949073
PTTG1 pituitary tumor-transforming 1 -0.944918
NEK3 NIMA-related kinase 3 -0.93733
SLC39A5 solute carrier family 39 (zinc transporter), member 5 -0.937078
CCDC97 coiled-coil domain containing 97 -0.936777
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 -0.931672
UNC5C unc-5 homolog C (C. elegans) -0.931433
NARS asparaginyl-tRNA synthetase -0.931242
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 -0.929731
DPP4 dipeptidyl-peptidase 4 -0.928668
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae) -0.927817
GSPT1 G1 to S phase transition 1 -0.927754
CHMP6 charged multivesicular body protein 6 -0.926143
MATR3 matrin 3 -0.924993
PHLDA2 pleckstrin homology-like domain, family A, member 2 -0.924651
MCOLN1 mucolipin 1 -0.923114
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) -0.92199
GUSB glucuronidase, beta -0.921088
HOXB8 homeobox B8 -0.91878
PARD6A par-6 family cell polarity regulator alpha -0.911422
HIST3H2A histone cluster 3, H2a -0.911277
FABP5 fatty acid binding protein 5 (psoriasis-associated) -0.910145
RAD1 RAD1 checkpoint DNA exonuclease -0.906894
COQ10A coenzyme Q10 homolog A (S. cerevisiae) -0.904821
EIF4A1 eukaryotic translation initiation factor 4A1 -0.900237
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 -0.898677
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 -0.89733
C11ORF86 chromosome 11 open reading frame 86 -0.897221
SLC30A9 solute carrier family 30 (zinc transporter), member 9 -0.896837
UGDH UDP-glucose 6-dehydrogenase -0.891309
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 -0.890303
NR1I2 nuclear receptor subfamily 1, group I, member 2 -0.888252
TMEM116 transmembrane protein 116 -0.887129
EMC2 ER membrane protein complex subunit 2 -0.881545
CYB561 cytochrome b561 -0.880004
PEX7 peroxisomal biogenesis factor 7 -0.878923
CDK19 cyclin-dependent kinase 19 -0.878763
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 -0.876291
PM20D1 peptidase M20 domain containing 1 -0.871851
SAP130 Sin3A-associated protein, 130kDa -0.87166
ANKRD11 ankyrin repeat domain 11 -0.871023
REEP3 receptor accessory protein 3 -0.870945
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -0.870881
PIGY phosphatidylinositol glycan anchor biosynthesis, class Y -0.865923
DHRS4 dehydrogenase/reductase (SDR family) member 4 -0.861203
ERO1LB ERO1-like beta (S. cerevisiae) -0.859966
APLP2 amyloid beta (A4) precursor-like protein 2 -0.858861
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 -0.856302
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae) -0.851662
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -0.85139
POU2F3 POU class 2 homeobox 3 -0.849957
CD99L2 CD99 molecule-like 2 -0.848003
RENBP renin binding protein -0.84207
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor -0.838684
MAN2B2 mannosidase, alpha, class 2B, member 2 -0.83786
GRN granulin -0.8357
AKAP1 A kinase (PRKA) anchor protein 1 -0.827663
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 -0.824036
KLF3 Kruppel-like factor 3 (basic) -0.821883
SLC16A4 solute carrier family 16, member 4 -0.818453
HECA headcase homolog (Drosophila) -0.816043
C19ORF67 chromosome 19 open reading frame 67 -0.814973
TXNDC15 thioredoxin domain containing 15 -0.812416
RAB17 RAB17, member RAS oncogene family -0.811947
CADM4 cell adhesion molecule 4 -0.811027
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic -0.810079
ACSM3 acyl-CoA synthetase medium-chain family member 3 -0.808753
DAP death-associated protein -0.804446
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -0.803483
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 -0.80063
LMOD1 leiomodin 1 (smooth muscle) -0.798166
NUDT16L1 nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1 -0.797205
SIGMAR1 sigma non-opioid intracellular receptor 1 -0.796312
PLIN2 perilipin 2 -0.794933
SCOC short coiled-coil protein -0.794378
WDR45 WD repeat domain 45 -0.793265
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.791301
STK40 serine/threonine kinase 40 -0.791102
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) -0.7886
KIAA0020 KIAA0020 -0.785227
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -0.784513
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 -0.784022
ADAM9 ADAM metallopeptidase domain 9 -0.780653
MANF mesencephalic astrocyte-derived neurotrophic factor -0.777255
SLC25A39 solute carrier family 25, member 39 -0.776791
RUNX2 runt-related transcription factor 2 -0.774129
KCNK7 potassium channel, two pore domain subfamily K, member 7 -0.773545
NIPSNAP3A nipsnap homolog 3A (C. elegans) -0.76982
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 -0.76757
ZNF519 zinc finger protein 519 -0.766388
DHFR dihydrofolate reductase -0.764066
ATP7A ATPase, Cu++ transporting, alpha polypeptide -0.76373
MAVS mitochondrial antiviral signaling protein -0.759452
CBR1 carbonyl reductase 1 -0.758295
COL6A3 collagen, type VI, alpha 3 -0.756736
LPAR3 lysophosphatidic acid receptor 3 -0.753581