Nephronophthisis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description An autosomal recessive disease that is characterized by a chronic tubulointerstitial nephritis that progress to terminal renal failure during the second decade (juvenile form) or before the age of 5 years (infantile form) resulting from dysfunction of ciliary proteins (ciliopathy). (Human Disease Ontology, DOID_12712)
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Genes

595 genes co-occuring with the disease Nephronophthisis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
NPHP1 nephronophthisis 1 (juvenile) 3.812
NPHP4 nephronophthisis 4 3.61
INVS inversin 3.461
NPHP3 nephronophthisis 3 (adolescent) 3.445
CEP290 centrosomal protein 290kDa 3.372
RPGRIP1L RPGRIP1-like 3.301
IQCB1 IQ motif containing B1 3.284
NEK8 NIMA-related kinase 8 3.268
TMEM67 transmembrane protein 67 3.204
TTC21B tetratricopeptide repeat domain 21B 3.139
AHI1 Abelson helper integration site 1 3.128
NEK9 NIMA-related kinase 9 3.099
ANKS6 ankyrin repeat and sterile alpha motif domain containing 6 3.086
CEP164 centrosomal protein 164kDa 3.07
CC2D2A coiled-coil and C2 domain containing 2A 3.059
OFD1 oral-facial-digital syndrome 1 2.991
ARL13B ADP-ribosylation factor-like 13B 2.982
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 2.981
WDR19 WD repeat domain 19 2.955
IFT88 intraflagellar transport 88 2.95
SDCCAG8 serologically defined colon cancer antigen 8 2.943
TMEM216 transmembrane protein 216 2.939
IFT140 intraflagellar transport 140 2.925
MKS1 Meckel syndrome, type 1 2.917
B9D1 B9 protein domain 1 2.866
CEP83 centrosomal protein 83kDa 2.855
PKD1 polycystic kidney disease 1 (autosomal dominant) 2.825
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 2.815
GLIS2 GLIS family zinc finger 2 2.802
PKD2 polycystic kidney disease 2 (autosomal dominant) 2.787
B9D2 B9 protein domain 2 2.77
TCTN2 tectonic family member 2 2.757
TCTN1 tectonic family member 1 2.741
BBS1 Bardet-Biedl syndrome 1 2.729
BBS4 Bardet-Biedl syndrome 4 2.726
KIF3A kinesin family member 3A 2.719
TMEM231 transmembrane protein 231 2.714
IFT20 intraflagellar transport 20 2.661
RPGR retinitis pigmentosa GTPase regulator 2.66
UMOD uromodulin 2.651
IFT172 intraflagellar transport 172 2.637
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial 2.61
ANKS3 ankyrin repeat and sterile alpha motif domain containing 3 2.581
TMEM237 transmembrane protein 237 2.572
SCLT1 sodium channel and clathrin linker 1 2.545
IFT80 intraflagellar transport 80 2.54
IFT43 intraflagellar transport 43 2.535
BBS2 Bardet-Biedl syndrome 2 2.515
ARL3 ADP-ribosylation factor-like 3 2.514
RAB8A RAB8A, member RAS oncogene family 2.511
IFT54 intraflagellar transport 54 2.51
IFT122 intraflagellar transport 122 2.497
TCTN3 tectonic family member 3 2.496
WDR35 WD repeat domain 35 2.494
CCP110 centriolar coiled coil protein 110kDa 2.462
IFT52 intraflagellar transport 52 2.457
BBS7 Bardet-Biedl syndrome 7 2.437
C2CD3 C2 calcium-dependent domain containing 3 2.435
CEP89 centrosomal protein 89kDa 2.409
SLC41A1 solute carrier family 41 (magnesium transporter), member 1 2.405
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 2.403
TULP3 tubby like protein 3 2.4
CNTLN centlein, centrosomal protein 2.396
BBS5 Bardet-Biedl syndrome 5 2.395
CPLANE1 ciliogenesis and planar polarity effector complex subunit 1 2.39
CEP41 centrosomal protein 41kDa 2.378
IFT27 intraflagellar transport 27 2.378
RAB3IP RAB3A interacting protein 2.361
KIF17 kinesin family member 17 2.356
ARL13A ADP-ribosylation factor-like 13A 2.348
KIF7 kinesin family member 7 2.335
DCDC2 doublecortin domain containing 2 2.31
TMEM138 transmembrane protein 138 2.307
KIAA0586 KIAA0586 2.303
IFT74 intraflagellar transport 74 2.3
AVPR2 arginine vasopressin receptor 2 2.278
FBF1 Fas (TNFRSF6) binding factor 1 2.269
ZNF423 zinc finger protein 423 2.265
BBS10 Bardet-Biedl syndrome 10 2.263
MAPKBP1 mitogen-activated protein kinase binding protein 1 2.262
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 2.255
BBS9 Bardet-Biedl syndrome 9 2.248
TTBK2 tau tubulin kinase 2 2.236
IFT57 intraflagellar transport 57 2.224
HNF1B HNF1 homeobox B 2.222
TMEM107 transmembrane protein 107 2.215
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa 2.213
IFT46 intraflagellar transport 46 2.207
CSPP1 centrosome and spindle pole associated protein 1 2.206
SHH sonic hedgehog 2.203
CEP97 centrosomal protein 97kDa 2.203
IFT81 intraflagellar transport 81 2.203
BBS12 Bardet-Biedl syndrome 12 2.195
PCNT pericentrin 2.194
DZIP1L DAZ interacting zinc finger protein 1-like 2.193
SMO smoothened, frizzled class receptor 2.182
ALMS1 Alstrom syndrome protein 1 2.178
SSTR3 somatostatin receptor 3 2.152
KIF24 kinesin family member 24 2.132
CEP120 centrosomal protein 120kDa 2.118
TMEM17 transmembrane protein 17 2.104
GPR161 G protein-coupled receptor 161 2.097
CBY1 chibby homolog 1 (Drosophila) 2.097
TMEM218 transmembrane protein 218 2.091
PRKD1 protein kinase D1 2.091
GLI1 GLI family zinc finger 1 2.083
PAX2 paired box 2 2.078
BBIP1 BBSome interacting protein 1 2.068
EXOC5 exocyst complex component 5 2.066
SPATA7 spermatogenesis associated 7 2.058
IFT38 intraflagellar transport 38 2.054
GLI3 GLI family zinc finger 3 2.053
WDPCP WD repeat containing planar cell polarity effector 2.05
MALL mal, T-cell differentiation protein-like 2.046
IFT22 intraflagellar transport 22 2.046
RHO rhodopsin 2.045
HYLS1 hydrolethalus syndrome 1 2.039
DVL1 dishevelled segment polarity protein 1 2.022
NEK1 NIMA-related kinase 1 2.019
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 2.011
SLC41A3 solute carrier family 41, member 3 2.008
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 2.008
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 2.006
TTC8 tetratricopeptide repeat domain 8 2.005
KIF3B kinesin family member 3B 1.986
WNT9B wingless-type MMTV integration site family, member 9B 1.98
AQP2 aquaporin 2 (collecting duct) 1.978
VANGL2 VANGL planar cell polarity protein 2 1.959
OCRL oculocerebrorenal syndrome of Lowe 1.946
NXPH4 neurexophilin 4 1.938
SEPTIN2 septin 2 1.938
DNAAF4 dynein axonemal assembly factor 4 1.933
GLIS1 GLIS family zinc finger 1 1.932
COL4A5 collagen, type IV, alpha 5 1.925
CEP131 centrosomal protein 131kDa 1.923
GANAB glucosidase, alpha; neutral AB 1.919
NIN ninein (GSK3B interacting protein) 1.917
UNC119 unc-119 homolog (C. elegans) 1.914
RGPD6 RANBP2-like and GRIP domain containing 6 1.911
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 1.901
CCDC28B coiled-coil domain containing 28B 1.9
INTU inturned planar cell polarity protein 1.887
PTCH1 patched 1 1.886
SIX2 SIX homeobox 2 1.88
MCHR1 melanin-concentrating hormone receptor 1 1.878
RAB11A RAB11A, member RAS oncogene family 1.86
RCC1 regulator of chromosome condensation 1 1.851
PCM1 pericentriolar material 1 1.85
DNAH11 dynein, axonemal, heavy chain 11 1.848
CEP63 centrosomal protein 63kDa 1.845
COL4A4 collagen, type IV, alpha 4 1.842
PKD1L1 polycystic kidney disease 1 like 1 1.839
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 1.838
LCA5 Leber congenital amaurosis 5 1.835
GLI2 GLI family zinc finger 2 1.829
CEP104 centrosomal protein 104kDa 1.82
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 1.819
GLIS3 GLIS family zinc finger 3 1.817
BICC1 BicC family RNA binding protein 1 1.815
SLC41A2 solute carrier family 41 (magnesium transporter), member 2 1.813
RGPD5 RANBP2-like and GRIP domain containing 5 1.806
CETN2 centrin, EF-hand protein, 2 1.799
FAM186B family with sequence similarity 186, member B 1.79
FAT4 FAT atypical cadherin 4 1.78
ATXN10 ataxin 10 1.776
PRPH2 peripherin 2 (retinal degeneration, slow) 1.766
USH2A Usher syndrome 2A (autosomal recessive, mild) 1.762
TULP1 tubby like protein 1 1.761
EVC Ellis van Creveld protein 1.758
PIBF1 progesterone immunomodulatory binding factor 1 1.756
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.75
FOXJ1 forkhead box J1 1.737
CNGB1 cyclic nucleotide gated channel beta 1 1.725
SUFU suppressor of fused homolog (Drosophila) 1.717
DNAH5 dynein, axonemal, heavy chain 5 1.714
CYS1 cystin 1 1.711
TINAG tubulointerstitial nephritis antigen 1.706
DNAI1 dynein, axonemal, intermediate chain 1 1.705
ARF4 ADP-ribosylation factor 4 1.702
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 1.694
PPIAP39 peptidylprolyl isomerase A pseudogene 39 1.69
MUC1 mucin 1, cell surface associated 1.688
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 1.687
EVC2 Ellis van Creveld syndrome 2 1.685
CEP152 centrosomal protein 152kDa 1.684
ADCY6 adenylate cyclase 6 1.678
FUZ fuzzy planar cell polarity protein 1.675
ANKRD6 ankyrin repeat domain 6 1.674
DZIP1 DAZ interacting zinc finger protein 1 1.672
RPE65 retinal pigment epithelium-specific protein 65kDa 1.67
PODXL podocalyxin-like 1.67
COQ8B coenzyme Q8B 1.662
HDAC6 histone deacetylase 6 1.662
ADCY3 adenylate cyclase 3 1.659
ROM1 retinal outer segment membrane protein 1 1.657
CLCN5 chloride channel, voltage-sensitive 5 1.653
PCARE photoreceptor cilium actin regulator 1.649
ODF2 outer dense fiber of sperm tails 2 1.644
TMEM80 transmembrane protein 80 1.643
RABIF RAB interacting factor 1.641
PRKCSH protein kinase C substrate 80K-H 1.636
BCAR1 breast cancer anti-estrogen resistance 1 1.632
INF2 inverted formin, FH2 and WH2 domain containing 1.629
UNC119B unc-119 homolog B (C. elegans) 1.626
EXOC6 exocyst complex component 6 1.623
CROCC ciliary rootlet coiled-coil, rootletin 1.622
WT1 Wilms tumor 1 1.617
MCIDAS multiciliate differentiation and DNA synthesis associated cell cycle protein 1.615
EYS eyes shut homolog (Drosophila) 1.612
CCDC65 coiled-coil domain containing 65 1.611
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha 1.611
PRICKLE3 prickle homolog 3 (Drosophila) 1.61
EXOC4 exocyst complex component 4 1.607
CEP135 centrosomal protein 135kDa 1.607
RDH12 retinol dehydrogenase 12 (all-trans/9-cis/11-cis) 1.604
TTLL6 tubulin tyrosine ligase-like family member 6 1.602
GRK1 G protein-coupled receptor kinase 1 1.602
SASS6 spindle assembly 6 homolog (C. elegans) 1.602
PRICKLE2 prickle homolog 2 (Drosophila) 1.602
NEK4 NIMA-related kinase 4 1.598
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.597
EYA1 EYA transcriptional coactivator and phosphatase 1 1.596
TSC2 tuberous sclerosis 2 1.596
KIAA0753 KIAA0753 1.593
NEK2 NIMA-related kinase 2 1.592
LRRC45 leucine rich repeat containing 45 1.59
DVL2 dishevelled segment polarity protein 2 1.59
PRICKLE4 prickle homolog 4 (Drosophila) 1.588
LZTFL1 leucine zipper transcription factor-like 1 1.588
RCC1L RCC1 like 1.587
CEP170 centrosomal protein 170kDa 1.586
TBC1D32 TBC1 domain family, member 32 1.584
TTLL3 tubulin tyrosine ligase-like family member 3 1.581
DYNLT1 dynein, light chain, Tctex-type 1 1.58
TNPO1 transportin 1 1.578
PATJ PATJ crumbs cell polarity complex component 1.576
FAM161A family with sequence similarity 161, member A 1.575
CNGB3 cyclic nucleotide gated channel beta 3 1.572
APOL1 apolipoprotein L, 1 1.568
ACTN4 actinin, alpha 4 1.565
CFAP36 cilia and flagella associated protein 36 1.565
ARMC9 armadillo repeat containing 9 1.557
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 1.548
CRX cone-rod homeobox 1.546
WHRN whirlin 1.544
SALL1 spalt-like transcription factor 1 1.543
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 1.538
SEC63 SEC63 homolog (S. cerevisiae) 1.536
PLCE1 phospholipase C, epsilon 1 1.534
RAB28 RAB28, member RAS oncogene family 1.533
LMX1B LIM homeobox transcription factor 1, beta 1.525
WNT4 wingless-type MMTV integration site family, member 4 1.525
RSPH4A radial spoke head 4 homolog A (Chlamydomonas) 1.524
CPLANE2 ciliogenesis and planar polarity effector complex subunit 2 1.522
NDE1 nudE neurodevelopment protein 1 1.517
RAB23 RAB23, member RAS oncogene family 1.513
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 1.511
NPY2R neuropeptide Y receptor Y2 1.511
AATF apoptosis antagonizing transcription factor 1.509
DRC7 dynein regulatory complex subunit 7 1.508
LIMS3 LIM and senescent cell antigen-like domains 3 1.502
TRIM32 tripartite motif containing 32 1.5
CEP162 centrosomal protein 162kDa 1.5
NUP62 nucleoporin 62kDa 1.499
KIF2A kinesin heavy chain member 2A 1.499
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 1.495
CRB3 crumbs family member 3 1.492
EHD1 EH-domain containing 1 1.491
ARL2 ADP-ribosylation factor-like 2 1.489
DNAI2 dynein, axonemal, intermediate chain 2 1.485
PRCD progressive rod-cone degeneration 1.482
DNAH9 dynein, axonemal, heavy chain 9 1.482
CFAP57 cilia and flagella associated protein 57 1.481
CABP4 calcium binding protein 4 1.48
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 1.474
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 1.469
RFX2 regulatory factor X, 2 (influences HLA class II expression) 1.468
GRK7 G protein-coupled receptor kinase 7 1.467
KIAA0319 KIAA0319 1.462
KIFAP3 kinesin-associated protein 3 1.459
NEK11 NIMA-related kinase 11 1.452
RFX1 regulatory factor X, 1 (influences HLA class II expression) 1.451
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.45
ALB albumin 1.447
PRICKLE1 prickle homolog 1 (Drosophila) 1.445
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 1.444
GMNC geminin coiled-coil domain containing 1.443
AURKA aurora kinase A 1.44
NEK7 NIMA-related kinase 7 1.44
PKD2L1 polycystic kidney disease 2-like 1 1.438
TRPV4 transient receptor potential cation channel, subfamily V, member 4 1.438
MYO7A myosin VIIA 1.434
CBY3 chibby homolog 3 (Drosophila) 1.434
CETN1 centrin, EF-hand protein, 1 1.432
ZC3H11D zinc finger CCCH-type containing 11D 1.432
KIF12 kinesin family member 12 1.431
NUP188 nucleoporin 188kDa 1.429
GUCA1B guanylate cyclase activator 1B (retina) 1.429
PLK1 polo-like kinase 1 1.427
PRPF31 pre-mRNA processing factor 31 1.422
ADGRV1 adhesion G protein-coupled receptor V1 1.422
CETN3 centrin, EF-hand protein, 3 1.422
PLK4 polo-like kinase 4 1.42
CNGA3 cyclic nucleotide gated channel alpha 3 1.41
WDR62 WD repeat domain 62 1.409
CCNO cyclin O 1.403
TXNDC15 thioredoxin domain containing 15 1.402
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta 1.4
LRP2 low density lipoprotein receptor-related protein 2 1.394
CALML3 calmodulin-like 3 1.392
TUB tubby bipartite transcription factor 1.391
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.39
STX3 syntaxin 3 1.387
FOXD1 forkhead box D1 1.387
CALML4 calmodulin-like 4 1.385
DNAAF1 dynein, axonemal, assembly factor 1 1.385
CALML6 calmodulin-like 6 1.385
WNT11 wingless-type MMTV integration site family, member 11 1.384
CALML5 calmodulin-like 5 1.382
ZIC3 Zic family member 3 1.38
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.38
FLNA filamin A, alpha 1.375
POC1B POC1 centriolar protein B 1.375
JADE1 jade family PHD finger 1 1.373
INPP5B inositol polyphosphate-5-phosphatase, 75kDa 1.373
CUBN cubilin (intrinsic factor-cobalamin receptor) 1.368
GUCA1A guanylate cyclase activator 1A (retina) 1.367
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 1.363
CDC42 cell division cycle 42 1.363
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.362
DNAH6 dynein, axonemal, heavy chain 6 1.36
SMAD9 SMAD family member 9 1.36
SAV1 salvador family WW domain containing protein 1 1.356
NEK6 NIMA-related kinase 6 1.356
EXOC3 exocyst complex component 3 1.355
HOXD11 homeobox D11 1.354
DAND5 DAN domain family member 5, BMP antagonist 1.353
TGFB1 transforming growth factor, beta 1 1.352
NME3 NME/NM23 nucleoside diphosphate kinase 3 1.351
DAW1 dynein assembly factor with WDR repeat domains 1 1.344
IHH indian hedgehog 1.343
RP1L1 retinitis pigmentosa 1-like 1 1.343
CEP76 centrosomal protein 76kDa 1.343
KCTD17 potassium channel tetramerization domain containing 17 1.341
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2 1.34
RSPH9 radial spoke head 9 homolog (Chlamydomonas) 1.339
CNGA1 cyclic nucleotide gated channel alpha 1 1.334
RABEP1 rabaptin, RAB GTPase binding effector protein 1 1.33
VANGL1 VANGL planar cell polarity protein 1 1.321
REN renin 1.32
GAS8 growth arrest-specific 8 1.32
TUBE1 tubulin, epsilon 1 1.312
ADCY5 adenylate cyclase 5 1.311
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.31
USH1G Usher syndrome 1G (autosomal recessive) 1.309
PDE4C phosphodiesterase 4C, cAMP-specific 1.308
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 1.306
CD2AP CD2-associated protein 1.306
DEUP1 deuterosome assembly protein 1 1.304
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 1.301
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.296
WNT5A wingless-type MMTV integration site family, member 5A 1.294
TUBD1 tubulin, delta 1 1.293
POC1A POC1 centriolar protein A 1.293
IMPG1 interphotoreceptor matrix proteoglycan 1 1.288
PACS1 phosphofurin acidic cluster sorting protein 1 1.286
DCDC2B doublecortin domain containing 2B 1.285
HNF4A hepatocyte nuclear factor 4, alpha 1.285
PAX8 paired box 8 1.285
CDH16 cadherin 16, KSP-cadherin 1.285
DCHS1 dachsous cadherin-related 1 1.284
TOGARAM1 TOG array regulator of axonemal microtubules 1 1.283
TRPC6 transient receptor potential cation channel, subfamily C, member 6 1.283
EXOC8 exocyst complex component 8 1.283
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.282
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 1.277
CEP350 centrosomal protein 350kDa 1.277
C11ORF24 chromosome 11 open reading frame 24 1.276
DRC1 dynein regulatory complex subunit 1 1.275
DNAAF3 dynein, axonemal, assembly factor 3 1.274
REEP6 receptor accessory protein 6 1.273
CDK5RAP2 CDK5 regulatory subunit associated protein 2 1.273
NUP93 nucleoporin 93kDa 1.271
MYH14 myosin, heavy chain 14, non-muscle 1.267
WWTR1 WW domain containing transcription regulator 1 1.267
RHOA ras homolog family member A 1.266
EFHC1 EF-hand domain (C-terminal) containing 1 1.264
CRB2 crumbs family member 2 1.261
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 1.261
DNAH8 dynein, axonemal, heavy chain 8 1.26
RGS9BP regulator of G protein signaling 9 binding protein 1.257
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 1.255
CC2D2B coiled-coil and C2 domain containing 2B 1.255
PMPCB peptidase (mitochondrial processing) beta 1.255
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 1.254
LHX1 LIM homeobox 1 1.253
PARD6A par-6 family cell polarity regulator alpha 1.253
DGKE diacylglycerol kinase, epsilon 64kDa 1.252
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor 1.251
CEP19 centrosomal protein 19kDa 1.251
SAG S-antigen; retina and pineal gland (arrestin) 1.249
SH2D4B SH2 domain containing 4B 1.248
CCDC14 coiled-coil domain containing 14 1.248
FREM2 FRAS1 related extracellular matrix protein 2 1.244
PTK2B protein tyrosine kinase 2 beta 1.244
CLCNKB chloride channel, voltage-sensitive Kb 1.242
GSK3B glycogen synthase kinase 3 beta 1.24
DNAH1 dynein, axonemal, heavy chain 1 1.238
DYNLL1 dynein, light chain, LC8-type 1 1.234
NUP133 nucleoporin 133kDa 1.233
ZMYND12 zinc finger, MYND-type containing 12 1.232
EXOC1 exocyst complex component 1 1.231
COQ6 coenzyme Q6 monooxygenase 1.23
STK11 serine/threonine kinase 11 1.228
NINL ninein-like 1.227
PKD1L3 polycystic kidney disease 1-like 3 1.227
CEP192 centrosomal protein 192kDa 1.225
TRIP11 thyroid hormone receptor interactor 11 1.223
MAK male germ cell-associated kinase 1.222
RD3 retinal degeneration 3 1.222
HOXB7 homeobox B7 1.221
AGXT alanine-glyoxylate aminotransferase 1.219
AGBL5 ATP/GTP binding protein-like 5 1.219
TEKT1 tektin 1 1.219
CCDC40 coiled-coil domain containing 40 1.219
IQSEC1 IQ motif and Sec7 domain 1 1.218
DNAH7 dynein, axonemal, heavy chain 7 1.217
RASA1 RAS p21 protein activator (GTPase activating protein) 1 1.214
SST somatostatin 1.213
AXIN1 axin 1 1.209
NEK5 NIMA-related kinase 5 1.208
BSND barttin CLCNK-type chloride channel accessory beta subunit 1.208
PTPRU protein tyrosine phosphatase, receptor type, U 1.206
JAG1 jagged 1 1.204
ALG8 ALG8, alpha-1,3-glucosyltransferase 1.201
HAVCR1 hepatitis A virus cellular receptor 1 1.198
FXYD2 FXYD domain containing ion transport regulator 2 1.198
RTTN rotatin 1.198
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 1.197
MROH6 maestro heat-like repeat family member 6 1.195
ARRB2 arrestin, beta 2 1.194
ACTB actin, beta 1.192
PMPCA peptidase (mitochondrial processing) alpha 1.191
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1 1.191
DCTN1 dynactin 1 1.187
MIPEP mitochondrial intermediate peptidase 1.183
DDX59 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 1.181
KIF13B kinesin family member 13B 1.18
SLC66A1 solute carrier family 66 member 1 1.178
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.178
TMEM69 transmembrane protein 69 1.176
GREB1L growth regulation by estrogen in breast cancer-like 1.176
HYDIN HYDIN, axonemal central pair apparatus protein 1.173
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 1.173
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma 1.171
CFAP300 cilia and flagella associated protein 300 1.17
NEDD1 neural precursor cell expressed, developmentally down-regulated 1 1.17
RSPH3 radial spoke 3 homolog (Chlamydomonas) 1.168
LATS1 large tumor suppressor kinase 1 1.167
LGALS4 lectin, galactoside-binding, soluble, 4 1.166
LRP5 low density lipoprotein receptor-related protein 5 1.166
CDH17 cadherin 17, LI cadherin (liver-intestine) 1.165
LEFTY2 left-right determination factor 2 1.165
TTLL5 tubulin tyrosine ligase-like family member 5 1.165
ARRB1 arrestin, beta 1 1.163
CFAP52 cilia and flagella associated protein 52 1.163
FLNC filamin C, gamma 1.162
RSPH1 radial spoke head 1 homolog (Chlamydomonas) 1.16
CEP250 centrosomal protein 250kDa 1.159
TTLL10 tubulin tyrosine ligase-like family member 10 1.156
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 1.152
EFCC1 EF-hand and coiled-coil domain containing 1 1.152
FAM149B1 family with sequence similarity 149, member B1 1.15
TRIM8 tripartite motif containing 8 1.15
FLNB filamin B, beta 1.149
RCVRN recoverin 1.149
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit 1.147
MAPRE3 microtubule-associated protein, RP/EB family, member 3 1.141
SIX1 SIX homeobox 1 1.14
ACE angiotensin I converting enzyme 1.138
CLVS2 clavesin 2 1.136
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 1.131
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase 1.13
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 1.129
PCDH15 protocadherin-related 15 1.129
DNAAF2 dynein, axonemal, assembly factor 2 1.129
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 1.129
RANBP2 RAN binding protein 2 1.129
NEK10 NIMA-related kinase 10 1.129
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.128
SHROOM3 shroom family member 3 1.128
BMP4 bone morphogenetic protein 4 1.127
CEP72 centrosomal protein 72kDa 1.127
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.126
AVP arginine vasopressin 1.126
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3 1.124
STK38L serine/threonine kinase 38 like 1.123
SAXO2 stabilizer of axonemal microtubules 2 1.123
DNAH17 dynein, axonemal, heavy chain 17 1.119
RBM48 RNA binding motif protein 48 1.117
BLOC1S2 biogenesis of lysosomal organelles complex-1, subunit 2 1.117
KIRREL1 kirre like nephrin family adhesion molecule 1 1.112
EGF epidermal growth factor 1.111
AQP1 aquaporin 1 (Colton blood group) 1.111
MAP4 microtubule-associated protein 4 1.108
EVI5L ecotropic viral integration site 5-like 1.107
EXOC7 exocyst complex component 7 1.107
FZD4 frizzled class receptor 4 1.106
NEK3 NIMA-related kinase 3 1.105
CCDC102A coiled-coil domain containing 102A 1.104
RABEP2 rabaptin, RAB GTPase binding effector protein 2 1.104
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 1.103
STIL SCL/TAL1 interrupting locus 1.102
SEC61B Sec61 beta subunit 1.1
DAAM1 dishevelled associated activator of morphogenesis 1 1.099
SCRIB scribbled planar cell polarity protein 1.097
DCX doublecortin 1.096
CCDC63 coiled-coil domain containing 63 1.096
MTLN mitoregulin 1.096
CASR calcium-sensing receptor 1.091
AVPI1 arginine vasopressin-induced 1 1.089
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 1.088
USH1C Usher syndrome 1C (autosomal recessive, severe) 1.084
UNC45A unc-45 homolog A (C. elegans) 1.083
MYH9 myosin, heavy chain 9, non-muscle 1.083
POC5 POC5 centriolar protein 1.078
CDK5 cyclin-dependent kinase 5 1.077
SCAPER S-phase cyclin A-associated protein in the ER 1.075
TBL1X transducin (beta)-like 1X-linked 1.074
CCDC68 coiled-coil domain containing 68 1.072
CLRN1 clarin 1 1.068
NME7 NME/NM23 family member 7 1.067
FZD8 frizzled class receptor 8 1.067
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 1.066
DYNLL2 dynein, light chain, LC8-type 2 1.065
FHAD1 forkhead-associated (FHA) phosphopeptide binding domain 1 1.065
RFX3 regulatory factor X, 3 (influences HLA class II expression) 1.063
WNT7B wingless-type MMTV integration site family, member 7B 1.062
NUP205 nucleoporin 205kDa 1.061
CTNS cystinosin, lysosomal cystine transporter 1.061
FN1 fibronectin 1 1.061
C5ORF52 chromosome 5 open reading frame 52 1.061
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 1.06
TP53 tumor protein p53 1.058
ESPN espin 1.057
ANKMY2 ankyrin repeat and MYND domain containing 2 1.056
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 1.056
ZBTB14 zinc finger and BTB domain containing 14 1.055
PAX6 paired box 6 1.055
FGF9 fibroblast growth factor 9 1.054
PACRG PARK2 co-regulated 1.052
GOLGB1 golgin B1 1.052
SNX3 sorting nexin 3 1.052
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 1.051
CDH23 cadherin-related 23 1.05
FGF8 fibroblast growth factor 8 (androgen-induced) 1.048
NDEL1 nudE neurodevelopment protein 1-like 1 1.048
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 1.046
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 1.046
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 1.044
MAP2K1 mitogen-activated protein kinase kinase 1 1.042
ANKRD46 ankyrin repeat domain 46 1.042
WNT3A wingless-type MMTV integration site family, member 3A 1.038
FRAS1 Fraser extracellular matrix complex subunit 1 1.037
TMEM255A transmembrane protein 255A 1.035
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) 1.035
CST3 cystatin C 1.035
CDKN3 cyclin-dependent kinase inhibitor 3 1.034
STK36 serine/threonine kinase 36 1.031
NRL neural retina leucine zipper 1.03
ARR3 arrestin 3, retinal (X-arrestin) 1.028
CCDC39 coiled-coil domain containing 39 1.028
FAM168B family with sequence similarity 168, member B 1.027
ARHGEF19 Rho guanine nucleotide exchange factor (GEF) 19 1.025
HAP1 huntingtin-associated protein 1 1.025
GDNF glial cell derived neurotrophic factor 1.025
DCTN5 dynactin 5 (p25) 1.024
RAX2 retina and anterior neural fold homeobox 2 1.023
ST6GALNAC1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 1.023
VSX2 visual system homeobox 2 1.023
RFX4 regulatory factor X, 4 (influences HLA class II expression) 1.022
ZNF274 zinc finger protein 274 1.022
MERTK MER proto-oncogene, tyrosine kinase 1.02
COL4A1 collagen, type IV, alpha 1 1.019
CEP128 centrosomal protein 128kDa 1.019
KIF19 kinesin family member 19 1.019
DCTN2 dynactin 2 (p50) 1.013
AXIN2 axin 2 1.012
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase) 1.01
CNKSR2 connector enhancer of kinase suppressor of Ras 2 1.008
UPK3A uroplakin 3A 1.007
ARHGAP24 Rho GTPase activating protein 24 1.003
SLC22A14 solute carrier family 22, member 14 1.003
NKX2-2 NK2 homeobox 2 1.002
MOB2 MOB kinase activator 2 1.0