| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Neratinib (maleate) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Neratinib (maleate)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.140628 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.107958 |
| CANX | calnexin | 0.0942603 |
| MEST | mesoderm specific transcript | 0.0909496 |
| CADM2 | cell adhesion molecule 2 | 0.0871171 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0838156 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0800419 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0652979 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0652607 |
| UTRN | utrophin | 0.0609077 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0596403 |
| MGP | matrix Gla protein | 0.0575309 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0539002 |
| RANBP17 | RAN binding protein 17 | 0.0532813 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0529668 |
| TPK1 | thiamin pyrophosphokinase 1 | 0.0526811 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0523479 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0505792 |
| KAZN | kazrin, periplakin interacting protein | 0.0503637 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0501193 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0494166 |
| OGA | O-GlcNAcase | 0.0490795 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0490261 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0477516 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.04619 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0454449 |
| SEPTIN11 | septin 11 | 0.0451677 |
| VEGFA | vascular endothelial growth factor A | 0.0443298 |
| ENAH | enabled homolog (Drosophila) | 0.0439599 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0430131 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0426659 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0425633 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0424909 |
| NF1 | neurofibromin 1 | 0.042168 |
| GPHN | gephyrin | 0.04002 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0399816 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0390259 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0389903 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0389657 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0382919 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | 0.0376562 |
| GSE1 | Gse1 coiled-coil protein | 0.037271 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0367626 |
| PCBP2 | poly(rC) binding protein 2 | 0.0359057 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0357338 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0356586 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0355786 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0353713 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | 0.0353644 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0351128 |
| PTK2 | protein tyrosine kinase 2 | 0.0349895 |
| ENO1 | enolase 1, (alpha) | 0.0344488 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0343456 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0342697 |
| MAP4 | microtubule-associated protein 4 | 0.0340423 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.033974 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0339136 |
| NFIB | nuclear factor I/B | 0.0338817 |
| CUX1 | cut-like homeobox 1 | 0.0338375 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0337451 |
| EXOC6B | exocyst complex component 6B | 0.0334412 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0333601 |
| WWC2 | WW and C2 domain containing 2 | 0.0333343 |
| SMYD3 | SET and MYND domain containing 3 | 0.0332485 |
| CDK6 | cyclin-dependent kinase 6 | 0.0330846 |
| MATR3 | matrin 3 | 0.0328846 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0327086 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0326686 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0324898 |
| TUBB | tubulin, beta class I | 0.0322545 |
| JMJD1C | jumonji domain containing 1C | 0.0321283 |
| BPTF | bromodomain PHD finger transcription factor | 0.0317976 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0313434 |
| MEOX2 | mesenchyme homeobox 2 | 0.0309928 |
| CALR | calreticulin | 0.0304501 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0303398 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0301902 |
| ZNF148 | zinc finger protein 148 | 0.0301541 |
| MED13L | mediator complex subunit 13-like | 0.0300789 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | 0.0300508 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0297707 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0296696 |
| PRELID2 | PRELI domain containing 2 | 0.0296592 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0295827 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0295414 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0294435 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0294364 |
| PEG10 | paternally expressed 10 | 0.0293963 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0293222 |
| ZNF292 | zinc finger protein 292 | 0.029267 |
| TMSB4X | thymosin beta 4, X-linked | 0.0291414 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0291299 |
| SRPK1 | SRSF protein kinase 1 | 0.0289431 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0289364 |
| ITGAV | integrin, alpha V | 0.0288589 |
| RSF1 | remodeling and spacing factor 1 | 0.0288211 |
| IL6ST | interleukin 6 signal transducer | 0.0287954 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0285447 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0284927 |
| SRPK2 | SRSF protein kinase 2 | 0.0284288 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.124619 |
| TMSB10 | thymosin beta 10 | -0.0769622 |
| RPS12 | ribosomal protein S12 | -0.0706761 |
| RPL23 | ribosomal protein L23 | -0.0600566 |
| RPS6 | ribosomal protein S6 | -0.0574485 |
| RPL37A | ribosomal protein L37a | -0.056094 |
| RPS8 | ribosomal protein S8 | -0.0531557 |
| RPL35A | ribosomal protein L35a | -0.0476082 |
| ACTG1 | actin gamma 1 | -0.0466385 |
| MT2A | metallothionein 2A | -0.0444455 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0434162 |
| RACK1 | receptor for activated C kinase 1 | -0.0428623 |
| RPL34 | ribosomal protein L34 | -0.040548 |
| RPS3 | ribosomal protein S3 | -0.0403331 |
| RPLP1 | ribosomal protein, large, P1 | -0.0400023 |
| RPL12 | ribosomal protein L12 | -0.0383587 |
| RPL31 | ribosomal protein L31 | -0.0380517 |
| RPL9 | ribosomal protein L9 | -0.0374596 |
| RPS24 | ribosomal protein S24 | -0.0370938 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0359658 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0341815 |
| RPS19 | ribosomal protein S19 | -0.0338711 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0331698 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0325652 |
| RPS2 | ribosomal protein S2 | -0.0311257 |
| RPS4X | ribosomal protein S4, X-linked | -0.0309278 |
| RPL36 | ribosomal protein L36 | -0.0302047 |
| RPL7 | ribosomal protein L7 | -0.0291063 |
| RPL37 | ribosomal protein L37 | -0.0289136 |
| RPLP2 | ribosomal protein, large, P2 | -0.0287623 |
| RPS14 | ribosomal protein S14 | -0.0285383 |
| RPS10 | ribosomal protein S10 | -0.0284031 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0281513 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0271751 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.027136 |
| RPL11 | ribosomal protein L11 | -0.027028 |
| HBP1 | HMG-box transcription factor 1 | -0.0267652 |
| RPS17 | ribosomal protein S17 | -0.026723 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0263181 |
| RPL26 | ribosomal protein L26 | -0.0259537 |
| RPS29 | ribosomal protein S29 | -0.0256156 |
| S100A9 | S100 calcium binding protein A9 | -0.0243375 |
| FTL | ferritin, light polypeptide | -0.0242744 |
| IER3 | immediate early response 3 | -0.0242616 |
| RPS15 | ribosomal protein S15 | -0.0238897 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0236778 |
| RPL32 | ribosomal protein L32 | -0.0236526 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.023631 |
| RPL27 | ribosomal protein L27 | -0.0236002 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0229727 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0224396 |
| CREBBP | CREB binding protein | -0.0223919 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0223444 |
| RPL19 | ribosomal protein L19 | -0.0223391 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.022284 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0222794 |
| KMT5B | lysine methyltransferase 5B | -0.0221208 |
| RPL35 | ribosomal protein L35 | -0.0219338 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | -0.0218133 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0213671 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.021176 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0209093 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0206114 |
| ZC3H13 | zinc finger CCCH-type containing 13 | -0.0205684 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0202992 |
| YBX3 | Y box binding protein 3 | -0.0199576 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0197012 |
| RBM4 | RNA binding motif protein 4 | -0.0194817 |
| RPS21 | ribosomal protein S21 | -0.0191166 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0189832 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.018859 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0187742 |
| KDM3B | lysine (K)-specific demethylase 3B | -0.0184376 |
| RFX7 | regulatory factor X, 7 | -0.0183529 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | -0.0182362 |
| RPS27A | ribosomal protein S27a | -0.0182189 |
| AASS | aminoadipate-semialdehyde synthase | -0.0181253 |
| GPX4 | glutathione peroxidase 4 | -0.0179713 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0178452 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0178073 |
| RB1 | retinoblastoma 1 | -0.0177648 |
| SLC25A33 | solute carrier family 25 (pyrimidine nucleotide carrier), member 33 | -0.0177263 |
| RSL24D1 | ribosomal L24 domain containing 1 | -0.0177245 |
| RPL5 | ribosomal protein L5 | -0.0176246 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0174364 |
| S100A6 | S100 calcium binding protein A6 | -0.0172344 |
| MTPN | myotrophin | -0.0172055 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.017186 |
| RAB6A | RAB6A, member RAS oncogene family | -0.017158 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0169511 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0169194 |
| RPLP0 | ribosomal protein, large, P0 | -0.0167611 |
| RPS25 | ribosomal protein S25 | -0.0167051 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0166765 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0166564 |
| HLA-E | major histocompatibility complex, class I, E | -0.0165616 |
| TOP1 | topoisomerase (DNA) I | -0.016384 |
| FOXO3 | forkhead box O3 | -0.0163441 |
| BRD7 | bromodomain containing 7 | -0.0163029 |
| LAMB3 | laminin, beta 3 | -0.0161503 |
