| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Neratinib (maleate) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Neratinib (maleate)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | 0.12778 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.12557 |
| LMO7 | LIM domain 7 | 0.081721 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0602626 |
| NTN4 | netrin 4 | 0.0561435 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0559189 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0529147 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0526713 |
| KLF6 | Kruppel-like factor 6 | 0.0496785 |
| NDRG1 | N-myc downstream regulated 1 | 0.0484411 |
| MYO5B | myosin VB | 0.0368714 |
| TXNRD1 | thioredoxin reductase 1 | 0.0361586 |
| SMAD3 | SMAD family member 3 | 0.034847 |
| ATXN1 | ataxin 1 | 0.0307662 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0282892 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0280336 |
| BCL2L1 | BCL2-like 1 | 0.0264675 |
| RPL35A | ribosomal protein L35a | 0.0261761 |
| TNS1 | tensin 1 | 0.0247675 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0238279 |
| DST | dystonin | 0.0236335 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0236275 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.0221038 |
| TJP1 | tight junction protein 1 | 0.0218207 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0214356 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0213298 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0209122 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0207885 |
| VIM | vimentin | 0.0195506 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0190744 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0189516 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0188042 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0186615 |
| MYOF | myoferlin | 0.0186462 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0183694 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0183456 |
| PDE10A | phosphodiesterase 10A | 0.0183242 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0182825 |
| SNX9 | sorting nexin 9 | 0.0182595 |
| FAM13A | family with sequence similarity 13, member A | 0.0181544 |
| TJP2 | tight junction protein 2 | 0.0181333 |
| VEGFA | vascular endothelial growth factor A | 0.0180311 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0179615 |
| LPIN2 | lipin 2 | 0.0177827 |
| CTBP2 | C-terminal binding protein 2 | 0.0176166 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0175377 |
| RNF213 | ring finger protein 213 | 0.0173823 |
| SVIL | supervillin | 0.0172941 |
| TMEM65 | transmembrane protein 65 | 0.0170493 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0167877 |
| RPS23 | ribosomal protein S23 | 0.0164896 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0160595 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0158697 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.0157513 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0151602 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0150481 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0150063 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0149474 |
| HMGA1 | high mobility group AT-hook 1 | 0.0148382 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0147345 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 0.0146317 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0145983 |
| CLIC5 | chloride intracellular channel 5 | 0.0145421 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0142572 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0140929 |
| PGCKA1 | PDCD10 and GCKIII kinases associated 1 | 0.0139726 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | 0.0138643 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0138554 |
| DENND4C | DENN/MADD domain containing 4C | 0.0137009 |
| RPS14 | ribosomal protein S14 | 0.0134999 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0134162 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0133953 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0133803 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0133175 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0131 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0130194 |
| PCDHB16 | protocadherin beta 16 | 0.0129253 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0129076 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0129043 |
| CPNE8 | copine VIII | 0.0128983 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0128363 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0127385 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0126466 |
| RPL12 | ribosomal protein L12 | 0.0125887 |
| SLTM | SAFB-like, transcription modulator | 0.0124715 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.012308 |
| ATF4 | activating transcription factor 4 | 0.0122903 |
| EGFR | epidermal growth factor receptor | 0.0122537 |
| UGT8 | UDP glycosyltransferase 8 | 0.0121342 |
| ATP9A | ATPase, class II, type 9A | 0.0120362 |
| MT2A | metallothionein 2A | 0.0119452 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0116273 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.011565 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0115283 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0112806 |
| AFDN | afadin, adherens junction formation factor | 0.0112006 |
| CCNYL1 | cyclin Y-like 1 | 0.0111961 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0110983 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0110685 |
| AXIN2 | axin 2 | 0.0110666 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.127246 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.114302 |
| UBC | ubiquitin C | -0.0966736 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0865471 |
| ACTN4 | actinin, alpha 4 | -0.0858031 |
| PTMA | prothymosin, alpha | -0.0824931 |
| RPS27A | ribosomal protein S27a | -0.0792112 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0769429 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0760045 |
| JUN | jun proto-oncogene | -0.0732649 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0687795 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0674542 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0670319 |
| AHNAK | AHNAK nucleoprotein | -0.066593 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0638501 |
| KRT8 | keratin 8, type II | -0.0621261 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0604819 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0603178 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0599752 |
| KRT20 | keratin 20, type I | -0.0577362 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0577006 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0567741 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0540023 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0513536 |
| LAMA4 | laminin, alpha 4 | -0.050203 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0482083 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0474848 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0472905 |
| YPEL2 | yippee-like 2 (Drosophila) | -0.0461325 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0438362 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0437745 |
| ENO1 | enolase 1, (alpha) | -0.0429425 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0417603 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0412277 |
| OGA | O-GlcNAcase | -0.0400951 |
| VMP1 | vacuole membrane protein 1 | -0.0395374 |
| EHF | ets homologous factor | -0.0391412 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0391158 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.038813 |
| POF1B | premature ovarian failure, 1B | -0.0386692 |
| ANXA2 | annexin A2 | -0.0385486 |
| CANX | calnexin | -0.0385151 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0374181 |
| SET | SET nuclear proto-oncogene | -0.0369649 |
| SERINC5 | serine incorporator 5 | -0.0363016 |
| INTS6 | integrator complex subunit 6 | -0.0353387 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0346876 |
| SBF2 | SET binding factor 2 | -0.034158 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0341177 |
| RPL4 | ribosomal protein L4 | -0.0339822 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0338214 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0335939 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0335596 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0335574 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0333566 |
| RPS3 | ribosomal protein S3 | -0.0331339 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0327654 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0326337 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0324441 |
| TRIB1 | tribbles pseudokinase 1 | -0.0317006 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0316269 |
| EPCAM | epithelial cell adhesion molecule | -0.0314547 |
| PTK2 | protein tyrosine kinase 2 | -0.0310678 |
| RPL23 | ribosomal protein L23 | -0.0309908 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0308699 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0306995 |
| NF1 | neurofibromin 1 | -0.030173 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0297567 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0297358 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0294734 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0291219 |
| DGKH | diacylglycerol kinase, eta | -0.0288848 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0284314 |
| GOLGB1 | golgin B1 | -0.0283068 |
| TOP1 | topoisomerase (DNA) I | -0.0282305 |
| MKI67 | marker of proliferation Ki-67 | -0.0282229 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0281732 |
| BPTF | bromodomain PHD finger transcription factor | -0.0278203 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0275669 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0275327 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0273173 |
| ZNF207 | zinc finger protein 207 | -0.0273063 |
| HYOU1 | hypoxia up-regulated 1 | -0.0272734 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0272516 |
| ACTG1 | actin gamma 1 | -0.0271737 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.027046 |
| PRELID2 | PRELI domain containing 2 | -0.0269369 |
| FAT1 | FAT atypical cadherin 1 | -0.0268914 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0268651 |
| SQSTM1 | sequestosome 1 | -0.0266788 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0266252 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0265788 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.026553 |
| TFRC | transferrin receptor | -0.0264691 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0264398 |
| WASF2 | WAS protein family, member 2 | -0.0264231 |
| NUP98 | nucleoporin 98kDa | -0.0263087 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0259851 |
| HMGB2 | high mobility group box 2 | -0.0259635 |
| DIAPH3 | diaphanous-related formin 3 | -0.0258611 |
