| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Neratinib (maleate) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Neratinib (maleate)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AHNAK | AHNAK nucleoprotein | 0.124194 |
| FLNB | filamin B, beta | 0.0993139 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0914375 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0887096 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0886103 |
| ASPH | aspartate beta-hydroxylase | 0.0868081 |
| PLEC | plectin | 0.0858542 |
| MSN | moesin | 0.0814182 |
| TGM2 | transglutaminase 2 | 0.0759509 |
| LMO7 | LIM domain 7 | 0.0747823 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.073911 |
| EZR | ezrin | 0.062954 |
| MYOF | myoferlin | 0.0597707 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0596602 |
| MEF2A | myocyte enhancer factor 2A | 0.0575792 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0560435 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.054247 |
| RAI14 | retinoic acid induced 14 | 0.0510348 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0506037 |
| TPM3 | tropomyosin 3 | 0.0470483 |
| PRELID2 | PRELI domain containing 2 | 0.046896 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0457958 |
| APP | amyloid beta (A4) precursor protein | 0.045334 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0453015 |
| DOK5 | docking protein 5 | 0.0444862 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0436224 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0424876 |
| EMP1 | epithelial membrane protein 1 | 0.0406671 |
| TXNRD1 | thioredoxin reductase 1 | 0.0402501 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0402207 |
| RASAL2 | RAS protein activator like 2 | 0.0392586 |
| PGK1 | phosphoglycerate kinase 1 | 0.0388393 |
| MXRA5 | matrix-remodelling associated 5 | 0.0386858 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0385589 |
| OSMR | oncostatin M receptor | 0.0384309 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0383513 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0381229 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0377467 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0377367 |
| MCL1 | myeloid cell leukemia 1 | 0.0374727 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0365245 |
| AOPEP | aminopeptidase O (putative) | 0.0363054 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0362714 |
| CEP250 | centrosomal protein 250kDa | 0.0360074 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0358674 |
| RAD51B | RAD51 paralog B | 0.0349333 |
| SLK | STE20-like kinase | 0.0347163 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0344831 |
| ECE1 | endothelin converting enzyme 1 | 0.0343756 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0331272 |
| PRSS23 | protease, serine, 23 | 0.0330473 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0329925 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0328752 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0324385 |
| LRRC8C | leucine rich repeat containing 8 family, member C | 0.0323736 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0323257 |
| LAMA5 | laminin, alpha 5 | 0.0321642 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0321598 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0321125 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0318793 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0316798 |
| DST | dystonin | 0.0314897 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0314878 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0314487 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0310118 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0305625 |
| IFI44L | interferon-induced protein 44-like | 0.0304419 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0300274 |
| PCBP2 | poly(rC) binding protein 2 | 0.0300119 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0299398 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0299356 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0297953 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0297102 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0296314 |
| PTK2 | protein tyrosine kinase 2 | 0.0293347 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0293173 |
| PODXL | podocalyxin-like | 0.0290588 |
| AFAP1 | actin filament associated protein 1 | 0.028882 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0287774 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0287154 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0287117 |
| CDK6 | cyclin-dependent kinase 6 | 0.028485 |
| AMOTL1 | angiomotin like 1 | 0.0278131 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0277893 |
| TXNIP | thioredoxin interacting protein | 0.0276459 |
| MEGF6 | multiple EGF-like-domains 6 | 0.0272881 |
| ACTN4 | actinin, alpha 4 | 0.0272404 |
| CD9 | CD9 molecule | 0.027102 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0270427 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.026768 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0266426 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0264515 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0262163 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0260637 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0253845 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.025008 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | 0.0246886 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0246416 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0246414 |
| TPM4 | tropomyosin 4 | 0.0246197 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.097421 |
| B2M | beta-2-microglobulin | -0.0930289 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0832774 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0734086 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0605907 |
| HLA-B | major histocompatibility complex, class I, B | -0.054783 |
| PTMA | prothymosin, alpha | -0.0541375 |
| RPL11 | ribosomal protein L11 | -0.052285 |
| TMSB10 | thymosin beta 10 | -0.0508538 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0491239 |
| HM13 | histocompatibility (minor) 13 | -0.047694 |
| RPS8 | ribosomal protein S8 | -0.0473208 |
| RPS3 | ribosomal protein S3 | -0.0466632 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0461281 |
| INTS6 | integrator complex subunit 6 | -0.045884 |
| RPS21 | ribosomal protein S21 | -0.0427159 |
| RPS24 | ribosomal protein S24 | -0.042457 |
| CLU | clusterin | -0.0407988 |
| RPS13 | ribosomal protein S13 | -0.0386803 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.038132 |
| RPL23 | ribosomal protein L23 | -0.0376125 |
| RPL9 | ribosomal protein L9 | -0.0373816 |
| S100A9 | S100 calcium binding protein A9 | -0.0364378 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0343301 |
| HMGA2 | high mobility group AT-hook 2 | -0.0324937 |
| FTL | ferritin, light polypeptide | -0.0323584 |
| RPS25 | ribosomal protein S25 | -0.0309834 |
| NDRG1 | N-myc downstream regulated 1 | -0.0309374 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0308581 |
| RPS27A | ribosomal protein S27a | -0.0303463 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0302704 |
| FKBP5 | FK506 binding protein 5 | -0.0302664 |
| RPL37A | ribosomal protein L37a | -0.0301233 |
| COG6 | component of oligomeric golgi complex 6 | -0.0300274 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0296454 |
| RPL35A | ribosomal protein L35a | -0.0293361 |
| RPS19 | ribosomal protein S19 | -0.0292624 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0291544 |
| TMSB4X | thymosin beta 4, X-linked | -0.0278987 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0277701 |
| S100A2 | S100 calcium binding protein A2 | -0.0274219 |
| RPL26 | ribosomal protein L26 | -0.0268192 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0266933 |
| SQLE | squalene epoxidase | -0.0262532 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0261351 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0258361 |
| RPS12 | ribosomal protein S12 | -0.0256407 |
| RPLP2 | ribosomal protein, large, P2 | -0.025601 |
| RPL31 | ribosomal protein L31 | -0.0244436 |
| MT1X | metallothionein 1X | -0.0243493 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0242625 |
| SP100 | SP100 nuclear antigen | -0.0241705 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0235503 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0235106 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0234918 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0231006 |
| POMP | proteasome maturation protein | -0.0229246 |
| RPS29 | ribosomal protein S29 | -0.0228147 |
| RPL35 | ribosomal protein L35 | -0.0227515 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.022608 |
| RPL32 | ribosomal protein L32 | -0.0215892 |
| IRS2 | insulin receptor substrate 2 | -0.0215553 |
| RPL12 | ribosomal protein L12 | -0.0215149 |
| RPS11 | ribosomal protein S11 | -0.0215091 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0210195 |
| PLTP | phospholipid transfer protein | -0.020807 |
| RPL37 | ribosomal protein L37 | -0.020555 |
| RPL34 | ribosomal protein L34 | -0.0204741 |
| RPL27A | ribosomal protein L27a | -0.0202706 |
| GOLGA4 | golgin A4 | -0.0200493 |
| SRP54 | signal recognition particle 54kDa | -0.0200325 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.019944 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0199078 |
| PMM2 | phosphomannomutase 2 | -0.0197929 |
| RPS17 | ribosomal protein S17 | -0.0196028 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.0195767 |
| SPAG9 | sperm associated antigen 9 | -0.0195586 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0195356 |
| RPS23 | ribosomal protein S23 | -0.0194544 |
| HLA-A | major histocompatibility complex, class I, A | -0.0193527 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0193135 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0192579 |
| TMEM263 | transmembrane protein 263 | -0.018877 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0184671 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0184038 |
| RPL7 | ribosomal protein L7 | -0.0183276 |
| RPL19 | ribosomal protein L19 | -0.0182525 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0180168 |
| GUK1 | guanylate kinase 1 | -0.0179632 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0175814 |
| RPL5 | ribosomal protein L5 | -0.0175724 |
| MT1E | metallothionein 1E | -0.0175536 |
| MORF4L2 | mortality factor 4 like 2 | -0.0173538 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0172707 |
| VCL | vinculin | -0.0172377 |
| RPL36 | ribosomal protein L36 | -0.0169901 |
| RPL7A | ribosomal protein L7a | -0.0169777 |
| ZNF217 | zinc finger protein 217 | -0.0169189 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0169173 |
| RPL30 | ribosomal protein L30 | -0.0168537 |
