| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Neratinib (maleate) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Neratinib (maleate)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.163022 |
| AHNAK | AHNAK nucleoprotein | 0.135959 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.128347 |
| TXNRD1 | thioredoxin reductase 1 | 0.127002 |
| DST | dystonin | 0.100856 |
| PCBP2 | poly(rC) binding protein 2 | 0.0853899 |
| MAP1B | microtubule-associated protein 1B | 0.0765407 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.075557 |
| RPS18 | ribosomal protein S18 | 0.0710288 |
| PLEC | plectin | 0.070903 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0676927 |
| MSN | moesin | 0.061442 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.059119 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0587548 |
| YBX3 | Y box binding protein 3 | 0.0580636 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0579495 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.05772 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0571413 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0554746 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0552628 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0551921 |
| MCL1 | myeloid cell leukemia 1 | 0.0533637 |
| RPL3 | ribosomal protein L3 | 0.0519229 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0514547 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0514291 |
| APP | amyloid beta (A4) precursor protein | 0.0495559 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0488931 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0482802 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0479737 |
| LIMA1 | LIM domain and actin binding 1 | 0.0476984 |
| FLNA | filamin A, alpha | 0.0468012 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0451893 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0440732 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0439746 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.043913 |
| RND3 | Rho family GTPase 3 | 0.0438993 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0424412 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0419107 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.0416821 |
| XPOT | exportin, tRNA | 0.0409797 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.040685 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.040423 |
| FRMD6 | FERM domain containing 6 | 0.0403245 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0401053 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0397822 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0396282 |
| EMP1 | epithelial membrane protein 1 | 0.0387927 |
| BDNF | brain-derived neurotrophic factor | 0.0381895 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0378398 |
| CORO1C | coronin, actin binding protein, 1C | 0.0377547 |
| ANK2 | ankyrin 2, neuronal | 0.0372534 |
| KLF6 | Kruppel-like factor 6 | 0.0371074 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0368823 |
| ASPH | aspartate beta-hydroxylase | 0.0364241 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0346646 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0337728 |
| CARS1 | cysteinyl-tRNA synthetase 1 | 0.0335445 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0335193 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0334827 |
| MED13L | mediator complex subunit 13-like | 0.0334553 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0333552 |
| TPM3 | tropomyosin 3 | 0.0331977 |
| ERBIN | erbb2 interacting protein | 0.0331704 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0325181 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.032273 |
| YARS1 | tyrosyl-tRNA synthetase 1 | 0.0312367 |
| ACTG1 | actin gamma 1 | 0.0311079 |
| NCKAP1 | NCK-associated protein 1 | 0.0310291 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0309633 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0308327 |
| RPS2 | ribosomal protein S2 | 0.0306368 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.030629 |
| PAPPA2 | pappalysin 2 | 0.0306141 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0306026 |
| NAV3 | neuron navigator 3 | 0.0301532 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0298286 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0296707 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0295514 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0294901 |
| ACTN1 | actinin, alpha 1 | 0.0288251 |
| HMGA1 | high mobility group AT-hook 1 | 0.0282042 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0281531 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0279729 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.027927 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0277462 |
| RPS12 | ribosomal protein S12 | 0.0277316 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0275118 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0274515 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0270682 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.0268166 |
| FAM120A | family with sequence similarity 120A | 0.0267914 |
| RBM39 | RNA binding motif protein 39 | 0.0267157 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0267151 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0264498 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0263996 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0263072 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0262785 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0262564 |
| AEBP2 | AE binding protein 2 | 0.0258713 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0257274 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.205655 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.147315 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.126811 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.123234 |
| EXT1 | exostosin glycosyltransferase 1 | -0.114012 |
| GPC6 | glypican 6 | -0.109696 |
| LSAMP | limbic system-associated membrane protein | -0.108873 |
| VIM | vimentin | -0.107504 |
| DTNA | dystrobrevin, alpha | -0.100541 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0974072 |
| TMSB10 | thymosin beta 10 | -0.0965213 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0761759 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0724025 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0712235 |
| PTMA | prothymosin, alpha | -0.0694011 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0675528 |
| HMGA2 | high mobility group AT-hook 2 | -0.0610057 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0599228 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0551766 |
| CDH13 | cadherin 13 | -0.05483 |
| VCL | vinculin | -0.0489672 |
| FN1 | fibronectin 1 | -0.0474928 |
| EFNA5 | ephrin-A5 | -0.0474921 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0471173 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0455644 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0426927 |
| PTK2 | protein tyrosine kinase 2 | -0.0424497 |
| RPL35A | ribosomal protein L35a | -0.0411712 |
| RPS24 | ribosomal protein S24 | -0.0403589 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0380715 |
| KIAA1549L | KIAA1549-like | -0.0375307 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0365499 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0363315 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0359104 |
| NABP1 | nucleic acid binding protein 1 | -0.0345051 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0343083 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0338272 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0333511 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0319585 |
| ZNF804A | zinc finger protein 804A | -0.031955 |
| SP100 | SP100 nuclear antigen | -0.0316415 |
| HMGB1 | high mobility group box 1 | -0.031533 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0314627 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0311709 |
| DIAPH3 | diaphanous-related formin 3 | -0.0305583 |
| CAVIN1 | caveolae associated protein 1 | -0.0300656 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0300342 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0300229 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0296285 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0285092 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0281692 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0281477 |
| CFAP251 | cilia and flagella associated protein 251 | -0.0278858 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0275486 |
| RPS27A | ribosomal protein S27a | -0.0273152 |
| MYO10 | myosin X | -0.0261953 |
| ARHGAP18 | Rho GTPase activating protein 18 | -0.0260133 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0259964 |
| PCDH11X | protocadherin 11 X-linked | -0.0258511 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0251698 |
| TMEM263 | transmembrane protein 263 | -0.0248192 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0244976 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | -0.0241307 |
| RIGI | RNA sensor RIG-I | -0.0240089 |
| RPL9 | ribosomal protein L9 | -0.0238742 |
| VEPH1 | ventricular zone expressed PH domain-containing 1 | -0.0238318 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0234782 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0231128 |
| NAV1 | neuron navigator 1 | -0.0230868 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0229488 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0228706 |
| RPS6 | ribosomal protein S6 | -0.022753 |
| CENPF | centromere protein F, 350/400kDa | -0.02266 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0225942 |
| MT2A | metallothionein 2A | -0.0223922 |
| RPS21 | ribosomal protein S21 | -0.0222734 |
| CDK14 | cyclin-dependent kinase 14 | -0.0221187 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0217908 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0217423 |
| FRMD4A | FERM domain containing 4A | -0.021726 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0216543 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0213456 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0212302 |
| MKI67 | marker of proliferation Ki-67 | -0.0211151 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0210199 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0209888 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0209101 |
| NGLY1 | N-glycanase 1 | -0.0207367 |
| CALD1 | caldesmon 1 | -0.020573 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0205541 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0205316 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0201947 |
| PTCHD4 | patched domain containing 4 | -0.0201428 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0199238 |
| CCDC80 | coiled-coil domain containing 80 | -0.0196473 |
| FUS | FUS RNA binding protein | -0.0195708 |
| RPS19 | ribosomal protein S19 | -0.0195391 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0191993 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0188558 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0188496 |
