| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Neratinib (maleate) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Neratinib (maleate)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.16031 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.148916 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.136779 |
| FAT1 | FAT atypical cadherin 1 | 0.121098 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0948794 |
| PCBP2 | poly(rC) binding protein 2 | 0.0916754 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0895781 |
| DSPP | dentin sialophosphoprotein | 0.0867838 |
| LDHA | lactate dehydrogenase A | 0.0827069 |
| ONECUT3 | one cut homeobox 3 | 0.0784599 |
| CADPS | Ca++-dependent secretion activator | 0.0770417 |
| VEGFA | vascular endothelial growth factor A | 0.0755434 |
| TXNIP | thioredoxin interacting protein | 0.0733793 |
| RNF43 | ring finger protein 43 | 0.066558 |
| PKM | pyruvate kinase, muscle | 0.0662585 |
| AHNAK | AHNAK nucleoprotein | 0.0651815 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0647949 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0634153 |
| EZR | ezrin | 0.0627866 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0618506 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0594579 |
| ABHD2 | abhydrolase domain containing 2 | 0.058044 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0570153 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0555467 |
| RPL3 | ribosomal protein L3 | 0.0514632 |
| FOXP1 | forkhead box P1 | 0.0513845 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0510684 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0508438 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0478489 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0476625 |
| ENO1 | enolase 1, (alpha) | 0.0469814 |
| ITGA6 | integrin, alpha 6 | 0.0468368 |
| RNF145 | ring finger protein 145 | 0.0461944 |
| PRELID2 | PRELI domain containing 2 | 0.0460859 |
| PTEN | phosphatase and tensin homolog | 0.0447974 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0446297 |
| MED13L | mediator complex subunit 13-like | 0.0445673 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0438899 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0438886 |
| TPM3 | tropomyosin 3 | 0.0437799 |
| NDRG1 | N-myc downstream regulated 1 | 0.0425452 |
| PGK1 | phosphoglycerate kinase 1 | 0.0424094 |
| GPHN | gephyrin | 0.0415834 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0414275 |
| PIGR | polymeric immunoglobulin receptor | 0.0399038 |
| RPS18 | ribosomal protein S18 | 0.0396109 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0393659 |
| EREG | epiregulin | 0.0392836 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0388204 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0380683 |
| INSIG1 | insulin induced gene 1 | 0.0371258 |
| TNS4 | tensin 4 | 0.037019 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.037004 |
| FAM13A | family with sequence similarity 13, member A | 0.0366348 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0365595 |
| TRIM2 | tripartite motif containing 2 | 0.0364293 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0358534 |
| APP | amyloid beta (A4) precursor protein | 0.0358151 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0355763 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0352121 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0350546 |
| SETD5 | SET domain containing 5 | 0.0347334 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.034617 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0346018 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0345625 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0343762 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0336764 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0331304 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0328792 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0325096 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0323794 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.032037 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.031881 |
| PLS1 | plastin 1 | 0.031797 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0317616 |
| CDK19 | cyclin-dependent kinase 19 | 0.0314831 |
| S100A14 | S100 calcium binding protein A14 | 0.0311142 |
| PLEC | plectin | 0.0310594 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0306471 |
| FAM120A | family with sequence similarity 120A | 0.0305528 |
| DNM2 | dynamin 2 | 0.0304807 |
| VMP1 | vacuole membrane protein 1 | 0.0304535 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0304467 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.0303687 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.030177 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0300056 |
| CANX | calnexin | 0.0297553 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.029746 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0295889 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0290552 |
| DENND4C | DENN/MADD domain containing 4C | 0.0285782 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0285497 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0283668 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0282956 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0280033 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.027711 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0276639 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0276254 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0276178 |
| CCNY | cyclin Y | 0.0276085 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.200018 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.181244 |
| NPSR1 | neuropeptide S receptor 1 | -0.0999516 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0976617 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0939833 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0935677 |
| TMSB10 | thymosin beta 10 | -0.0907762 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0905157 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0886845 |
| RPL35A | ribosomal protein L35a | -0.0700934 |
| ACTG1 | actin gamma 1 | -0.0667624 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0519206 |
| RPS24 | ribosomal protein S24 | -0.045527 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0449151 |
| HMGB1 | high mobility group box 1 | -0.0444581 |
| IER3 | immediate early response 3 | -0.0440536 |
| RPL9 | ribosomal protein L9 | -0.0430952 |
| RPLP1 | ribosomal protein, large, P1 | -0.0426731 |
| RPS8 | ribosomal protein S8 | -0.0413494 |
| RPS6 | ribosomal protein S6 | -0.0398485 |
| RPL34 | ribosomal protein L34 | -0.0393132 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0378482 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0371873 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0367972 |
| TFF1 | trefoil factor 1 | -0.0367814 |
| S100A6 | S100 calcium binding protein A6 | -0.0364727 |
| LAMA4 | laminin, alpha 4 | -0.0357077 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0350839 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.034088 |
| RPLP2 | ribosomal protein, large, P2 | -0.0334941 |
| LSAMP | limbic system-associated membrane protein | -0.0315773 |
| EGFR | epidermal growth factor receptor | -0.0308901 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0291711 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0283832 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0283592 |
| KLK10 | kallikrein-related peptidase 10 | -0.0282834 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0280463 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0279922 |
| RNF217 | ring finger protein 217 | -0.0277618 |
| VCL | vinculin | -0.0267918 |
| RPS21 | ribosomal protein S21 | -0.026729 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0265358 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0264655 |
| RPS27A | ribosomal protein S27a | -0.0253683 |
| RPL38 | ribosomal protein L38 | -0.0249257 |
| AGR2 | anterior gradient 2 | -0.0248152 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0242032 |
| RIGI | RNA sensor RIG-I | -0.024035 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0236486 |
| MT2A | metallothionein 2A | -0.0235835 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0234773 |
| TUBA1B | tubulin, alpha 1b | -0.0230644 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0222754 |
| DEK | DEK proto-oncogene | -0.0214879 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | -0.0214297 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | -0.0212371 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0210716 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0209972 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0203863 |
| AHI1 | Abelson helper integration site 1 | -0.0203336 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0200514 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0200185 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0197612 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0197548 |
| RPL7A | ribosomal protein L7a | -0.0196202 |
| RRBP1 | ribosome binding protein 1 | -0.0195419 |
| FERMT1 | fermitin family member 1 | -0.019425 |
| FBXO11 | F-box protein 11 | -0.0191033 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0187819 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | -0.0187442 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0187276 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0185246 |
| EHBP1 | EH domain binding protein 1 | -0.0184411 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0179224 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0179067 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0178514 |
| H3-3B | H3.3 histone B | -0.0176428 |
| RPL30 | ribosomal protein L30 | -0.0175335 |
| RPS10 | ribosomal protein S10 | -0.0173742 |
| USP53 | ubiquitin specific peptidase 53 | -0.0171562 |
| HDAC2 | histone deacetylase 2 | -0.0170671 |
| S100A10 | S100 calcium binding protein A10 | -0.0169908 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0169013 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0165998 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0165134 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.0164305 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0163135 |
| RPS16 | ribosomal protein S16 | -0.0162914 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0162888 |
| POMP | proteasome maturation protein | -0.0160355 |
| NPR2 | natriuretic peptide receptor 2 | -0.0160315 |
| RPS29 | ribosomal protein S29 | -0.0160197 |
| RPL31 | ribosomal protein L31 | -0.015926 |
| FOSL1 | FOS-like antigen 1 | -0.0158378 |
| RPL23 | ribosomal protein L23 | -0.0158108 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0153688 |
| CALU | calumenin | -0.015357 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0152329 |
| RPL36A | ribosomal protein L36a | -0.0152287 |
| ZNF33A | zinc finger protein 33A | -0.0152252 |
