| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Neratinib (maleate) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Neratinib (maleate)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.179761 |
| SEPTIN9 | septin 9 | 0.1382 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.11131 |
| SMAD3 | SMAD family member 3 | 0.110023 |
| FNDC3B | fibronectin type III domain containing 3B | 0.107847 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.106191 |
| FBL | fibrillarin | 0.103076 |
| AHNAK | AHNAK nucleoprotein | 0.0990315 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0922079 |
| PCBP2 | poly(rC) binding protein 2 | 0.0906692 |
| PTK2 | protein tyrosine kinase 2 | 0.0903755 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0875287 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0842056 |
| ASPH | aspartate beta-hydroxylase | 0.0836342 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0823512 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0820917 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0813154 |
| DST | dystonin | 0.0759742 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0757547 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0756098 |
| PKM | pyruvate kinase, muscle | 0.0706697 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0676792 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0673196 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0658792 |
| TXNRD1 | thioredoxin reductase 1 | 0.0640075 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0637181 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0625367 |
| TPM3 | tropomyosin 3 | 0.0589718 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0560953 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0560069 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0556244 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.05552 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0554661 |
| FMNL2 | formin-like 2 | 0.0549943 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.054496 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0538388 |
| NAV2 | neuron navigator 2 | 0.0529974 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0518862 |
| SFTPA2 | surfactant protein A2 | 0.0518417 |
| ZFP36 | ZFP36 ring finger protein | 0.0512676 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.051021 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.0503007 |
| CTBP2 | C-terminal binding protein 2 | 0.0498455 |
| MAP3K10 | mitogen-activated protein kinase kinase kinase 10 | 0.0488958 |
| MSN | moesin | 0.0487952 |
| NHSL1 | NHS-like 1 | 0.0486128 |
| PLEC | plectin | 0.0477752 |
| RAD51B | RAD51 paralog B | 0.047483 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0460378 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0460355 |
| SLC35F3 | solute carrier family 35, member F3 | 0.045741 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0456676 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0451895 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0449861 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.043602 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0429838 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0429096 |
| TNS3 | tensin 3 | 0.042687 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0422407 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0422229 |
| LDHA | lactate dehydrogenase A | 0.0421178 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0417806 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0417027 |
| ANO6 | anoctamin 6 | 0.0412626 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0411647 |
| MYOF | myoferlin | 0.0411044 |
| POTEF | POTE ankyrin domain family, member F | 0.0404949 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | 0.0403443 |
| PDE10A | phosphodiesterase 10A | 0.0401533 |
| AFAP1 | actin filament associated protein 1 | 0.040132 |
| STC2 | stanniocalcin 2 | 0.0397338 |
| PRELID2 | PRELI domain containing 2 | 0.0396986 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0393547 |
| IPO7 | importin 7 | 0.0391916 |
| SQSTM1 | sequestosome 1 | 0.0390193 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0389538 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0387665 |
| MED13L | mediator complex subunit 13-like | 0.0381712 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0380331 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0379124 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0377273 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0369762 |
| UTRN | utrophin | 0.0366106 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0362893 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0361154 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0358965 |
| MYO10 | myosin X | 0.0355289 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0353743 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.0352339 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0348894 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0348333 |
| RNF213 | ring finger protein 213 | 0.0345403 |
| RPL3 | ribosomal protein L3 | 0.0344931 |
| APP | amyloid beta (A4) precursor protein | 0.0344099 |
| HMGA1 | high mobility group AT-hook 1 | 0.0343436 |
| SYNJ2 | synaptojanin 2 | 0.0336872 |
| ACTN4 | actinin, alpha 4 | 0.0335574 |
| CMIP | c-Maf inducing protein | 0.0331806 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0331566 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0331511 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | -0.134273 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.111435 |
| RPS16 | ribosomal protein S16 | -0.108787 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.098439 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0780227 |
| PTMA | prothymosin, alpha | -0.0754792 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0616248 |
| TMSB10 | thymosin beta 10 | -0.0549621 |
| CD44 | CD44 molecule (Indian blood group) | -0.0509554 |
| VIM | vimentin | -0.0473277 |
| RPL35A | ribosomal protein L35a | -0.042309 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0419218 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0386421 |
| RPS24 | ribosomal protein S24 | -0.0364387 |
| RPLP2 | ribosomal protein, large, P2 | -0.0333368 |
| EGR1 | early growth response 1 | -0.0293544 |
| H1-0 | H1.0 linker histone | -0.0283345 |
| RPL12 | ribosomal protein L12 | -0.0272294 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0271566 |
| ACTG1 | actin gamma 1 | -0.0269729 |
| RPS8 | ribosomal protein S8 | -0.0268665 |
| IER3 | immediate early response 3 | -0.0266788 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0257582 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0256428 |
| RPLP1 | ribosomal protein, large, P1 | -0.0248167 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0242285 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0233777 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0229685 |
| RPS5 | ribosomal protein S5 | -0.0226507 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0224465 |
| WDR45B | WD repeat domain 45B | -0.022293 |
| RPLP0 | ribosomal protein, large, P0 | -0.0220622 |
| RPS21 | ribosomal protein S21 | -0.0217207 |
| RPS19 | ribosomal protein S19 | -0.0214558 |
| RPS27A | ribosomal protein S27a | -0.0208343 |
| ZNF217 | zinc finger protein 217 | -0.0206362 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0197529 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0193779 |
| RPS25 | ribosomal protein S25 | -0.0191916 |
| RPL34 | ribosomal protein L34 | -0.0186526 |
| CAVIN1 | caveolae associated protein 1 | -0.0186352 |
| RPL36A | ribosomal protein L36a | -0.0177919 |
| RPL38 | ribosomal protein L38 | -0.0176903 |
| RPL26 | ribosomal protein L26 | -0.0174462 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0173902 |
| KLF6 | Kruppel-like factor 6 | -0.0172217 |
| VDAC1 | voltage-dependent anion channel 1 | -0.016639 |
| ANLN | anillin, actin binding protein | -0.016602 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0163697 |
| RPL37A | ribosomal protein L37a | -0.015979 |
| RPL36 | ribosomal protein L36 | -0.0158253 |
| MYSM1 | Myb-like, SWIRM and MPN domains 1 | -0.0156333 |
| ZNF546 | zinc finger protein 546 | -0.0152969 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0152009 |
| MORF4L2 | mortality factor 4 like 2 | -0.0151595 |
| HMGB1 | high mobility group box 1 | -0.015116 |
| NABP1 | nucleic acid binding protein 1 | -0.0149066 |
| RPL32 | ribosomal protein L32 | -0.0148906 |
| SERINC1 | serine incorporator 1 | -0.0146377 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0143338 |
| RPL9 | ribosomal protein L9 | -0.0143248 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0141008 |
| RPS3 | ribosomal protein S3 | -0.0140204 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.01391 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0139032 |
| TMEM263 | transmembrane protein 263 | -0.0138806 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0138433 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0138317 |
| SPAG9 | sperm associated antigen 9 | -0.0137956 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0137588 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0135717 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0135544 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0135295 |
| RAB1B | RAB1B, member RAS oncogene family | -0.0134782 |
| RPL30 | ribosomal protein L30 | -0.01334 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0131282 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0129981 |
| RPL11 | ribosomal protein L11 | -0.0127827 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | -0.0127821 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.012675 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0122817 |
| EIF3J | eukaryotic translation initiation factor 3, subunit J | -0.0121186 |
| RPL27A | ribosomal protein L27a | -0.01204 |
| RPL6 | ribosomal protein L6 | -0.012035 |
| RPL28 | ribosomal protein L28 | -0.0118723 |
| RPL19 | ribosomal protein L19 | -0.0117145 |
| RPL23 | ribosomal protein L23 | -0.0117103 |
| RPL4 | ribosomal protein L4 | -0.0115592 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0115306 |
| RPS13 | ribosomal protein S13 | -0.0114964 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0113196 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0112611 |
| HLA-B | major histocompatibility complex, class I, B | -0.0110474 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0110402 |
| RPL31 | ribosomal protein L31 | -0.0110363 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0109944 |
| ARF1 | ADP-ribosylation factor 1 | -0.0108163 |
| RPL37 | ribosomal protein L37 | -0.0107977 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0107021 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | -0.0106755 |
