| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Neratinib (maleate) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Neratinib (maleate)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.126679 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.10136 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0889776 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0832034 |
| RTN4 | reticulon 4 | 0.0694742 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0681945 |
| GOLGA4 | golgin A4 | 0.0651768 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0619595 |
| JMJD1C | jumonji domain containing 1C | 0.061058 |
| ANK2 | ankyrin 2, neuronal | 0.0597877 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0591601 |
| ZNF292 | zinc finger protein 292 | 0.0569486 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0559964 |
| TXNRD1 | thioredoxin reductase 1 | 0.0529188 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0522953 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0516166 |
| EFNA5 | ephrin-A5 | 0.0496746 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0488344 |
| QKI | QKI, KH domain containing, RNA binding | 0.0460636 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0459485 |
| COG5 | component of oligomeric golgi complex 5 | 0.0452356 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.044483 |
| RBM39 | RNA binding motif protein 39 | 0.0442334 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0441239 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0429117 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0425767 |
| NBAS | neuroblastoma amplified sequence | 0.0415575 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0409334 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0391607 |
| TMEM65 | transmembrane protein 65 | 0.0380748 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0369246 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0363575 |
| VMP1 | vacuole membrane protein 1 | 0.0363354 |
| PGK1 | phosphoglycerate kinase 1 | 0.0358708 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0354471 |
| TMEM41B | transmembrane protein 41B | 0.0353657 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0347316 |
| EZR | ezrin | 0.0346957 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0345262 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0341744 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0337648 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.033738 |
| YAP1 | Yes-associated protein 1 | 0.0335167 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0333546 |
| TJP1 | tight junction protein 1 | 0.0333016 |
| SETD5 | SET domain containing 5 | 0.0332703 |
| FOXJ3 | forkhead box J3 | 0.0330861 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0330374 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0330203 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0327321 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0325901 |
| EGFR | epidermal growth factor receptor | 0.0325717 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0319241 |
| SBF2 | SET binding factor 2 | 0.0314154 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0314012 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.031397 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0313385 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0313277 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0309282 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0308947 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0305582 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0304732 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0304246 |
| RNF145 | ring finger protein 145 | 0.0300593 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0300528 |
| HDLBP | high density lipoprotein binding protein | 0.0298288 |
| USP3 | ubiquitin specific peptidase 3 | 0.0296662 |
| CDC73 | cell division cycle 73 | 0.0296603 |
| NUP58 | nucleoporin 58 | 0.0295479 |
| NCKAP1 | NCK-associated protein 1 | 0.0291945 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0289378 |
| SMYD3 | SET and MYND domain containing 3 | 0.0288411 |
| USP47 | ubiquitin specific peptidase 47 | 0.0275948 |
| MSI2 | musashi RNA-binding protein 2 | 0.027212 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0270619 |
| LOC112694756 | uncharaterized LOC112694756 | 0.026877 |
| TFG | TRK-fused gene | 0.0265072 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0264182 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0263551 |
| RREB1 | ras responsive element binding protein 1 | 0.0263054 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0262764 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0262316 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0260108 |
| HM13 | histocompatibility (minor) 13 | 0.0259823 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0256593 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0256196 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0255842 |
| TMEM135 | transmembrane protein 135 | 0.0255126 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0254807 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0253945 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0253928 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.0251679 |
| PTK2 | protein tyrosine kinase 2 | 0.0249259 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0249003 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0247912 |
| ZNF608 | zinc finger protein 608 | 0.0247102 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0244967 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0240839 |
| PHF21A | PHD finger protein 21A | 0.0240421 |
| FBXO11 | F-box protein 11 | 0.0240055 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.316243 |
| BMP10 | bone morphogenetic protein 10 | -0.128597 |
| MKI67 | marker of proliferation Ki-67 | -0.0899567 |
| NAV2 | neuron navigator 2 | -0.078104 |
| RPS8 | ribosomal protein S8 | -0.0747239 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0724765 |
| CENPF | centromere protein F, 350/400kDa | -0.0691666 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0666931 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0646202 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0632896 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0623645 |
| RPS6 | ribosomal protein S6 | -0.0606237 |
| RPS12 | ribosomal protein S12 | -0.0559196 |
| RPLP1 | ribosomal protein, large, P1 | -0.0547639 |
| RPS3 | ribosomal protein S3 | -0.0542868 |
| PKM | pyruvate kinase, muscle | -0.0542369 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.053391 |
| VCL | vinculin | -0.0527845 |
| RPL26 | ribosomal protein L26 | -0.0514614 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0491034 |
| DIAPH3 | diaphanous-related formin 3 | -0.0488987 |
| RPL37A | ribosomal protein L37a | -0.0456173 |
| HJURP | Holliday junction recognition protein | -0.0441555 |
| RPL35A | ribosomal protein L35a | -0.0434313 |
| MYO5C | myosin VC | -0.043361 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0428092 |
| RPL36 | ribosomal protein L36 | -0.0414823 |
| FOXP1 | forkhead box P1 | -0.0414403 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0411087 |
| RPL9 | ribosomal protein L9 | -0.0407014 |
| GLI3 | GLI family zinc finger 3 | -0.0406852 |
| RPL34 | ribosomal protein L34 | -0.0396205 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0391169 |
| TMSB10 | thymosin beta 10 | -0.0381165 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0379455 |
| S100A4 | S100 calcium binding protein A4 | -0.0378627 |
| RPL23 | ribosomal protein L23 | -0.0378566 |
| EMP3 | epithelial membrane protein 3 | -0.0377534 |
| TPX2 | TPX2, microtubule-associated | -0.0375716 |
| RPL31 | ribosomal protein L31 | -0.0369839 |
| TPM4 | tropomyosin 4 | -0.0358775 |
| CENPE | centromere protein E, 312kDa | -0.0354866 |
| RPL19 | ribosomal protein L19 | -0.0350654 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0342551 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0341133 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0339175 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.033839 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0337029 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.033252 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0332055 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0331004 |
| RRM2 | ribonucleotide reductase M2 | -0.0325036 |
| RPS13 | ribosomal protein S13 | -0.0319427 |
| RPS19 | ribosomal protein S19 | -0.0318781 |
| RPS27 | ribosomal protein S27 | -0.0318689 |
| NBEA | neurobeachin | -0.031819 |
| TMSB4X | thymosin beta 4, X-linked | -0.0315665 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0314489 |
| ZNF438 | zinc finger protein 438 | -0.0312994 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0312988 |
| RPL12 | ribosomal protein L12 | -0.0305063 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0298535 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.029749 |
| GSE1 | Gse1 coiled-coil protein | -0.0297018 |
| RPLP2 | ribosomal protein, large, P2 | -0.0291507 |
| PDE7B | phosphodiesterase 7B | -0.0287514 |
| RPS21 | ribosomal protein S21 | -0.0284279 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0283107 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0276079 |
| HSPB1 | heat shock 27kDa protein 1 | -0.027433 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.0272725 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0269194 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0261877 |
| RPS27A | ribosomal protein S27a | -0.0257081 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0254089 |
| CEP112 | centrosomal protein 112kDa | -0.0247598 |
| PTMS | parathymosin | -0.0247552 |
| HMGB1 | high mobility group box 1 | -0.0245549 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0240655 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0237424 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0235273 |
| ANLN | anillin, actin binding protein | -0.0233255 |
| ITGA10 | integrin, alpha 10 | -0.0233248 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0232267 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0231441 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0230648 |
| RPL11 | ribosomal protein L11 | -0.0230229 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.0228747 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0226189 |
| RPS17 | ribosomal protein S17 | -0.022605 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0225385 |
| PRDX2 | peroxiredoxin 2 | -0.02242 |
| RPL37 | ribosomal protein L37 | -0.0224172 |
| TPI1 | triosephosphate isomerase 1 | -0.0214674 |
| FMN1 | formin 1 | -0.0214098 |
| B2M | beta-2-microglobulin | -0.0213413 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0210531 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0207572 |
| RPS23 | ribosomal protein S23 | -0.0206937 |
| ARHGAP11A | Rho GTPase activating protein 11A | -0.0206346 |
