| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Neratinib (maleate) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Neratinib (maleate)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.20228 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.175805 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.172281 |
| COL6A3 | collagen, type VI, alpha 3 | 0.170735 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.129152 |
| VEGFA | vascular endothelial growth factor A | 0.11484 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.105857 |
| CD44 | CD44 molecule (Indian blood group) | 0.101531 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.100687 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0872686 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0848282 |
| MSN | moesin | 0.0826494 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0822297 |
| LDHA | lactate dehydrogenase A | 0.0798529 |
| SEPTIN9 | septin 9 | 0.0780612 |
| AHNAK | AHNAK nucleoprotein | 0.0748691 |
| DST | dystonin | 0.0741745 |
| PDE10A | phosphodiesterase 10A | 0.0709167 |
| PLIN2 | perilipin 2 | 0.0708241 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0697806 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0684822 |
| ENO1 | enolase 1, (alpha) | 0.0682284 |
| LOXL2 | lysyl oxidase-like 2 | 0.068192 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0677147 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0663856 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0653476 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0633405 |
| MLPH | melanophilin | 0.0621011 |
| COL5A1 | collagen, type V, alpha 1 | 0.0620448 |
| PCBP2 | poly(rC) binding protein 2 | 0.0609301 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0598136 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0583831 |
| RAD51B | RAD51 paralog B | 0.0569726 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0553298 |
| ASPH | aspartate beta-hydroxylase | 0.0548588 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.052738 |
| APP | amyloid beta (A4) precursor protein | 0.0522654 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0512265 |
| VCAN | versican | 0.0512075 |
| NAV2 | neuron navigator 2 | 0.0505029 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0504363 |
| NDRG1 | N-myc downstream regulated 1 | 0.050148 |
| PRELID2 | PRELI domain containing 2 | 0.0483569 |
| STC2 | stanniocalcin 2 | 0.0471488 |
| FMNL2 | formin-like 2 | 0.0458277 |
| MYOF | myoferlin | 0.045137 |
| OPTN | optineurin | 0.0449903 |
| C3 | complement component 3 | 0.0447037 |
| TMEM132D | transmembrane protein 132D | 0.044536 |
| SQSTM1 | sequestosome 1 | 0.0443282 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0437398 |
| CANX | calnexin | 0.0422789 |
| SFTPA2 | surfactant protein A2 | 0.0414609 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0413676 |
| ADM | adrenomedullin | 0.0412922 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0411177 |
| PFKP | phosphofructokinase, platelet | 0.0406346 |
| CEP250 | centrosomal protein 250kDa | 0.0405262 |
| TNS3 | tensin 3 | 0.0393415 |
| SMAD3 | SMAD family member 3 | 0.0393387 |
| RAI14 | retinoic acid induced 14 | 0.0386986 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0384994 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0378095 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0377852 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0377237 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0376693 |
| TRAM2 | translocation associated membrane protein 2 | 0.0371277 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0368115 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0367357 |
| PKM | pyruvate kinase, muscle | 0.0367102 |
| EGFR | epidermal growth factor receptor | 0.0364864 |
| PHF21A | PHD finger protein 21A | 0.0364707 |
| RPS18 | ribosomal protein S18 | 0.0364421 |
| PGK1 | phosphoglycerate kinase 1 | 0.0361064 |
| HDAC9 | histone deacetylase 9 | 0.0360772 |
| RNF213 | ring finger protein 213 | 0.0359477 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0358027 |
| MCL1 | myeloid cell leukemia 1 | 0.0356563 |
| NAV1 | neuron navigator 1 | 0.0356331 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0354806 |
| WWOX | WW domain containing oxidoreductase | 0.0350673 |
| CALR | calreticulin | 0.0350424 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0347822 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0347043 |
| MMP12 | matrix metallopeptidase 12 | 0.0341231 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0337318 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0335629 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.033456 |
| CDH13 | cadherin 13 | 0.0327799 |
| SYNJ2 | synaptojanin 2 | 0.0326158 |
| PHF3 | PHD finger protein 3 | 0.0320498 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0318269 |
| ARFGEF3 | ARFGEF family member 3 | 0.0317119 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0315095 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0308431 |
| ATXN1 | ataxin 1 | 0.030142 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0298568 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.029805 |
| UTRN | utrophin | 0.029568 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0293966 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.130699 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0838434 |
| HLA-B | major histocompatibility complex, class I, B | -0.0795226 |
| FRMD4A | FERM domain containing 4A | -0.0760386 |
| TMSB10 | thymosin beta 10 | -0.0680844 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0588405 |
| IER3 | immediate early response 3 | -0.0557752 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0556866 |
| RPL23 | ribosomal protein L23 | -0.0550337 |
| MKI67 | marker of proliferation Ki-67 | -0.0531282 |
| BICC1 | BicC family RNA binding protein 1 | -0.0505237 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0502138 |
| VCL | vinculin | -0.048224 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0472287 |
| CENPF | centromere protein F, 350/400kDa | -0.0464794 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0462203 |
| THBS1 | thrombospondin 1 | -0.0461614 |
| RPS24 | ribosomal protein S24 | -0.0458568 |
| ANLN | anillin, actin binding protein | -0.04457 |
| KYNU | kynureninase | -0.0428756 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0416235 |
| PTMA | prothymosin, alpha | -0.0413902 |
| NABP1 | nucleic acid binding protein 1 | -0.0412391 |
| RPS3 | ribosomal protein S3 | -0.040047 |
| MT2A | metallothionein 2A | -0.038651 |
| RPL35A | ribosomal protein L35a | -0.0383057 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0380154 |
| ACTG1 | actin gamma 1 | -0.0368628 |
| RPL37A | ribosomal protein L37a | -0.0366891 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0365353 |
| MORF4L2 | mortality factor 4 like 2 | -0.0342599 |
| DIAPH3 | diaphanous-related formin 3 | -0.0341449 |
| FN1 | fibronectin 1 | -0.033435 |
| RPL9 | ribosomal protein L9 | -0.0332892 |
| PALLD | palladin, cytoskeletal associated protein | -0.0327582 |
| FTL | ferritin, light polypeptide | -0.0322141 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0319569 |
| RPS6 | ribosomal protein S6 | -0.0308044 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0297712 |
| KIF4A | kinesin family member 4A | -0.0295481 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0290435 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0286185 |
| RPS8 | ribosomal protein S8 | -0.0276944 |
| RPLP2 | ribosomal protein, large, P2 | -0.0269948 |
| RPL32 | ribosomal protein L32 | -0.0268036 |
| RPLP1 | ribosomal protein, large, P1 | -0.0267556 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0261442 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0260747 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0260274 |
| RPS19 | ribosomal protein S19 | -0.0256493 |
| RPL12 | ribosomal protein L12 | -0.0252616 |
| TNNC1 | troponin C type 1 (slow) | -0.0252051 |
| CADM1 | cell adhesion molecule 1 | -0.0249474 |
| RPL36 | ribosomal protein L36 | -0.0248728 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.024499 |
| RPS4X | ribosomal protein S4, X-linked | -0.0236469 |
| TPX2 | TPX2, microtubule-associated | -0.0229084 |
| RPL26 | ribosomal protein L26 | -0.0227462 |
| RPLP0 | ribosomal protein, large, P0 | -0.0221031 |
| RBM39 | RNA binding motif protein 39 | -0.0220696 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0216266 |
| RPL11 | ribosomal protein L11 | -0.0216233 |
| RPS21 | ribosomal protein S21 | -0.0212469 |
| SRGN | serglycin | -0.0211786 |
| OSMR | oncostatin M receptor | -0.021067 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0210495 |
| DEK | DEK proto-oncogene | -0.0208917 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.020818 |
| PRR11 | proline rich 11 | -0.0206183 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | -0.0205473 |
| RPS27A | ribosomal protein S27a | -0.020477 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0204659 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0202538 |
| CENPE | centromere protein E, 312kDa | -0.0197169 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0196304 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0195435 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0195202 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0194624 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0194102 |
| RBMX | RNA binding motif protein, X-linked | -0.0191595 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0189774 |
| KIF18A | kinesin family member 18A | -0.018921 |
| WDR45B | WD repeat domain 45B | -0.0189138 |
| RACK1 | receptor for activated C kinase 1 | -0.0188302 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.018726 |
| COL1A1 | collagen, type I, alpha 1 | -0.0185559 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0184744 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0184414 |
| GOPC | golgi-associated PDZ and coiled-coil motif containing | -0.0184181 |
| WTAP | Wilms tumor 1 associated protein | -0.018414 |
| TMEM263 | transmembrane protein 263 | -0.0183219 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0182226 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0180765 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0180287 |
| EGR1 | early growth response 1 | -0.017956 |
| RIGI | RNA sensor RIG-I | -0.0178864 |
| THOC2 | THO complex 2 | -0.0176775 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0174007 |
| RPL30 | ribosomal protein L30 | -0.0173708 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.017362 |
