| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Neratinib (maleate) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Neratinib (maleate)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.143042 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.123486 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0803046 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0779838 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0779425 |
| AHNAK | AHNAK nucleoprotein | 0.0702997 |
| DSPP | dentin sialophosphoprotein | 0.0694088 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.065211 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0624356 |
| TXNRD1 | thioredoxin reductase 1 | 0.0608176 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0596364 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0595993 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0594522 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0594266 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0581293 |
| LDHA | lactate dehydrogenase A | 0.0576322 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0564581 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0549476 |
| SVIL | supervillin | 0.054934 |
| FAM3C | family with sequence similarity 3, member C | 0.0526517 |
| PRELID2 | PRELI domain containing 2 | 0.052336 |
| TMEM123 | transmembrane protein 123 | 0.0521593 |
| MAP4 | microtubule-associated protein 4 | 0.0511798 |
| CANX | calnexin | 0.0505398 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0501406 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0499674 |
| HDLBP | high density lipoprotein binding protein | 0.0494612 |
| STC2 | stanniocalcin 2 | 0.0491332 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0483992 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0476667 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0474139 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0464315 |
| PLEC | plectin | 0.0459718 |
| WWC1 | WW and C2 domain containing 1 | 0.0452221 |
| CTSA | cathepsin A | 0.0448754 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0448569 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0446525 |
| HM13 | histocompatibility (minor) 13 | 0.0444968 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0440396 |
| CUX1 | cut-like homeobox 1 | 0.0439816 |
| SNX9 | sorting nexin 9 | 0.0433048 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0432303 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.042427 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0420704 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0420085 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0417484 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0413269 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0412333 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0410994 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0408143 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0405578 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0403729 |
| CTBP2 | C-terminal binding protein 2 | 0.0402773 |
| SMAD3 | SMAD family member 3 | 0.039892 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0398671 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0381853 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0377222 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0372183 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0364264 |
| KRT18 | keratin 18, type I | 0.0363971 |
| BCL2L1 | BCL2-like 1 | 0.0362775 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0362343 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0362102 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0356706 |
| SETD5 | SET domain containing 5 | 0.0356442 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0352682 |
| FHIT | fragile histidine triad | 0.0350581 |
| DST | dystonin | 0.0349695 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0347668 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0345076 |
| GOLGA4 | golgin A4 | 0.0344359 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0343862 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0342235 |
| RAD51B | RAD51 paralog B | 0.0342147 |
| SBF2 | SET binding factor 2 | 0.0342051 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0340772 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0339141 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0338974 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0334056 |
| WWOX | WW domain containing oxidoreductase | 0.0332688 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0332564 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0332355 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0330577 |
| TJP1 | tight junction protein 1 | 0.0324797 |
| GOLGB1 | golgin B1 | 0.0322705 |
| FNBP1L | formin binding protein 1-like | 0.0318968 |
| LARP1 | La ribonucleoprotein domain family, member 1 | 0.0318645 |
| JMJD1C | jumonji domain containing 1C | 0.0316921 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0315711 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0314359 |
| ZNF148 | zinc finger protein 148 | 0.0312962 |
| COBL | cordon-bleu WH2 repeat protein | 0.0309963 |
| PGK1 | phosphoglycerate kinase 1 | 0.0308858 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0306801 |
| NF1 | neurofibromin 1 | 0.0305704 |
| SFTPA2 | surfactant protein A2 | 0.0304557 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0300731 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0297978 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0296706 |
| ANXA4 | annexin A4 | 0.0294468 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.115477 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.107433 |
| PTMA | prothymosin, alpha | -0.0992802 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0672293 |
| UBC | ubiquitin C | -0.058228 |
| RPS27A | ribosomal protein S27a | -0.0578647 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0570702 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0526186 |
| KRT8 | keratin 8, type II | -0.0491392 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0488964 |
| RPL23 | ribosomal protein L23 | -0.0481567 |
| RPS12 | ribosomal protein S12 | -0.0439077 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0409777 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0368922 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0361741 |
| JUN | jun proto-oncogene | -0.0357454 |
| ECT2 | epithelial cell transforming 2 | -0.0352179 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0347921 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.034536 |
| RPL37A | ribosomal protein L37a | -0.0341992 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0337837 |
| RBM25 | RNA binding motif protein 25 | -0.0328677 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0313283 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0310273 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.030854 |
| RPS3 | ribosomal protein S3 | -0.0302917 |
| CCNL1 | cyclin L1 | -0.0297581 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.0292912 |
| RPL36 | ribosomal protein L36 | -0.0286023 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0285515 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0284957 |
| INTS6 | integrator complex subunit 6 | -0.0281599 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0270298 |
| RPS19 | ribosomal protein S19 | -0.0261633 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0257377 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0256814 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0253957 |
| HMGB2 | high mobility group box 2 | -0.0252274 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0245265 |
| ITGA6 | integrin, alpha 6 | -0.0242711 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0241629 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0239054 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0235549 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0232847 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0230457 |
| RPL9 | ribosomal protein L9 | -0.0228661 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0228336 |
| RPL11 | ribosomal protein L11 | -0.0227123 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0225812 |
| SET | SET nuclear proto-oncogene | -0.0215876 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0214802 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.021143 |
| CENPE | centromere protein E, 312kDa | -0.0209544 |
| RPS21 | ribosomal protein S21 | -0.0209515 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0205699 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 | -0.0204585 |
| RPL26 | ribosomal protein L26 | -0.0200355 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | -0.0199922 |
| NOP58 | NOP58 ribonucleoprotein | -0.019619 |
| RPL5 | ribosomal protein L5 | -0.0193605 |
| H3-3B | H3.3 histone B | -0.0187304 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0186913 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0183777 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0183158 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0182864 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.018157 |
| TPX2 | TPX2, microtubule-associated | -0.0181379 |
| RCOR1 | REST corepressor 1 | -0.0179903 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0176753 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0176701 |
| RPL18 | ribosomal protein L18 | -0.0173851 |
| NAV2 | neuron navigator 2 | -0.0173813 |
| OGA | O-GlcNAcase | -0.0173727 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.0173646 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0173534 |
| RPL12 | ribosomal protein L12 | -0.0173361 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0172351 |
| DDX27 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 | -0.0172281 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | -0.0170316 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0168381 |
| DUSP5 | dual specificity phosphatase 5 | -0.0168041 |
| LAMB3 | laminin, beta 3 | -0.0167607 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.0165126 |
| CFAP161 | cilia and flagella associated protein 161 | -0.0164495 |
| HMGA2 | high mobility group AT-hook 2 | -0.0164346 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0164027 |
| TFRC | transferrin receptor | -0.0162799 |
| RRM2 | ribonucleotide reductase M2 | -0.0160324 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0160212 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.015998 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0158778 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0157883 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.0157217 |
| COX6C | cytochrome c oxidase subunit VIc | -0.0154875 |
| TFG | TRK-fused gene | -0.0154872 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0154771 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0154588 |
| CENPF | centromere protein F, 350/400kDa | -0.0154551 |
| LAMA4 | laminin, alpha 4 | -0.0154186 |
| FTL | ferritin, light polypeptide | -0.0151457 |
