| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Neratinib (maleate) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Neratinib (maleate)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.12316 |
| PCBP2 | poly(rC) binding protein 2 | 0.115467 |
| EZR | ezrin | 0.114355 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.106741 |
| RAD51B | RAD51 paralog B | 0.0958403 |
| CDH13 | cadherin 13 | 0.0949866 |
| WWOX | WW domain containing oxidoreductase | 0.0934555 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0882256 |
| ENO1 | enolase 1, (alpha) | 0.0878047 |
| AHNAK | AHNAK nucleoprotein | 0.0867995 |
| ASPH | aspartate beta-hydroxylase | 0.0836526 |
| NAV2 | neuron navigator 2 | 0.0819504 |
| FLNB | filamin B, beta | 0.0806816 |
| PLEC | plectin | 0.0782008 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0764012 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0704314 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0697252 |
| PGK1 | phosphoglycerate kinase 1 | 0.0689934 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0688408 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0681453 |
| LDHA | lactate dehydrogenase A | 0.0655044 |
| SYT1 | synaptotagmin I | 0.0643888 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0615852 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0610198 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0606457 |
| PKM | pyruvate kinase, muscle | 0.0593446 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0566311 |
| MSN | moesin | 0.0554446 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0549571 |
| POTEF | POTE ankyrin domain family, member F | 0.0549344 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0545147 |
| ANXA2 | annexin A2 | 0.0534031 |
| SEPTIN9 | septin 9 | 0.0526765 |
| FHIT | fragile histidine triad | 0.0525032 |
| EXOC4 | exocyst complex component 4 | 0.0514849 |
| ITGB4 | integrin, beta 4 | 0.0512395 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0474217 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0471849 |
| TPM4 | tropomyosin 4 | 0.0459749 |
| ITGA6 | integrin, alpha 6 | 0.0457002 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0455952 |
| ACTN1 | actinin, alpha 1 | 0.0454381 |
| KRT18 | keratin 18, type I | 0.044556 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0444687 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0440453 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0424213 |
| TPM3 | tropomyosin 3 | 0.040988 |
| RPL3 | ribosomal protein L3 | 0.0404693 |
| HDAC4 | histone deacetylase 4 | 0.039796 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0397268 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0396434 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0387808 |
| DIAPH2 | diaphanous-related formin 2 | 0.0384224 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0384179 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.037632 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0375346 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0375249 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0367058 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0364791 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0349779 |
| CUX1 | cut-like homeobox 1 | 0.0347293 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0344427 |
| SKAP1 | src kinase associated phosphoprotein 1 | 0.0343382 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0341267 |
| EHBP1 | EH domain binding protein 1 | 0.0340516 |
| CANX | calnexin | 0.0337376 |
| STC2 | stanniocalcin 2 | 0.0330716 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | 0.0324852 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0323301 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0322897 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.0322501 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0321351 |
| CBX5 | chromobox homolog 5 | 0.0318079 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0317866 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0317461 |
| HMGA1 | high mobility group AT-hook 1 | 0.0312807 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0312323 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0311908 |
| AIG1 | androgen-induced 1 | 0.0310621 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0310579 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0307614 |
| FLNA | filamin A, alpha | 0.0305641 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0303533 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0299946 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0299855 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0299063 |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta | 0.0298649 |
| BRD4 | bromodomain containing 4 | 0.0298478 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0298111 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0295312 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0294603 |
| DOCK9 | dedicator of cytokinesis 9 | 0.0291905 |
| FAM120A | family with sequence similarity 120A | 0.029188 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0291769 |
| NHSL1 | NHS-like 1 | 0.0291297 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0290928 |
| CMIP | c-Maf inducing protein | 0.028988 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.0289675 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0288128 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.028597 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.163491 |
| RPL35A | ribosomal protein L35a | -0.0739857 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0675053 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0648138 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0519017 |
| RPL23 | ribosomal protein L23 | -0.0501585 |
| RPS24 | ribosomal protein S24 | -0.048608 |
| PTMA | prothymosin, alpha | -0.0485209 |
| RPL26 | ribosomal protein L26 | -0.0482403 |
| RPLP1 | ribosomal protein, large, P1 | -0.0442417 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | -0.0423012 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0396799 |
| RPS19 | ribosomal protein S19 | -0.0391387 |
| RPL11 | ribosomal protein L11 | -0.0384233 |
| RPL37A | ribosomal protein L37a | -0.038095 |
| RPL9 | ribosomal protein L9 | -0.03753 |
| RPL12 | ribosomal protein L12 | -0.0362722 |
| RPS6 | ribosomal protein S6 | -0.0361694 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0346051 |
| RPS27A | ribosomal protein S27a | -0.0343958 |
| BMP5 | bone morphogenetic protein 5 | -0.0320597 |
| RPS21 | ribosomal protein S21 | -0.0310301 |
| HMGB1 | high mobility group box 1 | -0.0303526 |
| RPLP2 | ribosomal protein, large, P2 | -0.029801 |
| RPS8 | ribosomal protein S8 | -0.0297283 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0294821 |
| RPL34 | ribosomal protein L34 | -0.0273525 |
| RPL36 | ribosomal protein L36 | -0.027012 |
| PRRC2C | proline-rich coiled-coil 2C | -0.02628 |
| TMSB10 | thymosin beta 10 | -0.0262065 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0257506 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0253846 |
| OGA | O-GlcNAcase | -0.0251503 |
| AOPEP | aminopeptidase O (putative) | -0.0249345 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.024825 |
| RPL32 | ribosomal protein L32 | -0.0246096 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0244861 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0244102 |
| EFNB2 | ephrin-B2 | -0.0232833 |
| RPS3 | ribosomal protein S3 | -0.0231725 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0230611 |
| RPL38 | ribosomal protein L38 | -0.0222877 |
| FOXP1 | forkhead box P1 | -0.0221333 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0212953 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0212627 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0204936 |
| HMGB2 | high mobility group box 2 | -0.0203951 |
| MT2A | metallothionein 2A | -0.0202993 |
| RPL35 | ribosomal protein L35 | -0.0200118 |
| IER3 | immediate early response 3 | -0.0198835 |
| RPS4X | ribosomal protein S4, X-linked | -0.019809 |
| RPL31 | ribosomal protein L31 | -0.0196874 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0195844 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0187856 |
| PERP | PERP, TP53 apoptosis effector | -0.0186858 |
| H3-3B | H3.3 histone B | -0.0184249 |
| RACK1 | receptor for activated C kinase 1 | -0.0183472 |
| ZFR | zinc finger RNA binding protein | -0.0181824 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.018071 |
| RPL19 | ribosomal protein L19 | -0.0180181 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0180151 |
| RPL5 | ribosomal protein L5 | -0.0178138 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0178069 |
| CCDC82 | coiled-coil domain containing 82 | -0.0177838 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0176152 |
| PROX1 | prospero homeobox 1 | -0.0174338 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0173927 |
| RPL36A | ribosomal protein L36a | -0.0172432 |
| NF1 | neurofibromin 1 | -0.0171559 |
| RPL27A | ribosomal protein L27a | -0.016932 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0167206 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0166303 |
| ABHD2 | abhydrolase domain containing 2 | -0.0165731 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -0.0165662 |
| THOC2 | THO complex 2 | -0.0164676 |
| RPL30 | ribosomal protein L30 | -0.0163322 |
| RPS16 | ribosomal protein S16 | -0.0161985 |
| RPLP0 | ribosomal protein, large, P0 | -0.0161829 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0161776 |
| CEP95 | centrosomal protein 95kDa | -0.0160169 |
| RPS15 | ribosomal protein S15 | -0.015775 |
| SMOC2 | SPARC related modular calcium binding 2 | -0.0155658 |
| DCUN1D3 | DCN1, defective in cullin neddylation 1, domain containing 3 | -0.0155087 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0154749 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0151428 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.015142 |
| OXR1 | oxidation resistance 1 | -0.01509 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0150744 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0149618 |
| MORF4L2 | mortality factor 4 like 2 | -0.0148218 |
| RPL4 | ribosomal protein L4 | -0.0148173 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0147518 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0146581 |
| RPL18 | ribosomal protein L18 | -0.0146359 |
| SPATA13 | spermatogenesis associated 13 | -0.0143815 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0143215 |
| RPL7 | ribosomal protein L7 | -0.0142289 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0140689 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0140372 |
| RNF43 | ring finger protein 43 | -0.0139899 |
