Neratinib Gene Set
Genes
20 kinases inhibited by the Neratinib small molecule from the KinomeScan Kinase Inhibitor Targets dataset.
| Symbol |
Name |
Standardized Value |
|
ERBB3
|
erb-b2 receptor tyrosine kinase 3
|
1.36211
|
|
EGFR
|
epidermal growth factor receptor
|
1.36211
|
|
STK24
|
serine/threonine kinase 24
|
1.33582
|
|
MAP4K5
|
mitogen-activated protein kinase kinase kinase kinase 5
|
1.29393
|
|
SLK
|
STE20-like kinase
|
1.25436
|
|
STK3
|
serine/threonine kinase 3
|
1.25436
|
|
STK26
|
serine/threonine protein kinase 26
|
1.20983
|
|
BLK
|
BLK proto-oncogene, Src family tyrosine kinase
|
1.1424
|
|
LCK
|
LCK proto-oncogene, Src family tyrosine kinase
|
1.09992
|
|
MAP3K3
|
mitogen-activated protein kinase kinase kinase 3
|
1.09415
|
|
BTK
|
Bruton agammaglobulinemia tyrosine kinase
|
1.06105
|
|
MAP3K4
|
mitogen-activated protein kinase kinase kinase 4
|
1.04035
|
|
MAP4K2
|
mitogen-activated protein kinase kinase kinase kinase 2
|
1.02071
|
|
AXL
|
AXL receptor tyrosine kinase
|
1.01127
|
|
TNIK
|
TRAF2 and NCK interacting kinase
|
0.984392
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
0.975893
|
|
MINK1
|
misshapen-like kinase 1
|
0.9517
|
|
MERTK
|
MER proto-oncogene, tyrosine kinase
|
0.895762
|
|
NUAK2
|
NUAK family, SNF1-like kinase, 2
|
0.883492
|
|
GAK
|
cyclin G associated kinase
|
0.850157
|
