| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Neratinib perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Neratinib_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.175607 |
| PDLIM5 | PDZ and LIM domain 5 | 0.090495 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0781006 |
| FLNB | filamin B, beta | 0.0700302 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0652546 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0642361 |
| RASAL2 | RAS protein activator like 2 | 0.0641949 |
| MSN | moesin | 0.0551062 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0508976 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0501868 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0478662 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.047328 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0463112 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0441665 |
| POTEF | POTE ankyrin domain family, member F | 0.0430238 |
| EGFR | epidermal growth factor receptor | 0.0385373 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0380982 |
| LUZP1 | leucine zipper protein 1 | 0.0380309 |
| RCOR1 | REST corepressor 1 | 0.0379247 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0378746 |
| RAI14 | retinoic acid induced 14 | 0.0377467 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0372504 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0371785 |
| LMO7 | LIM domain 7 | 0.0371359 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0370798 |
| INTS6 | integrator complex subunit 6 | 0.0365223 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0347449 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0345648 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0331832 |
| CLIC4 | chloride intracellular channel 4 | 0.0327054 |
| SULF1 | sulfatase 1 | 0.0323629 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0322624 |
| RAD51B | RAD51 paralog B | 0.031721 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0310583 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.030529 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0300947 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0294804 |
| EGR1 | early growth response 1 | 0.0291547 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0288581 |
| MCL1 | myeloid cell leukemia 1 | 0.0282777 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0282321 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0282287 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0280531 |
| EXOC4 | exocyst complex component 4 | 0.0278253 |
| DGKH | diacylglycerol kinase, eta | 0.0277672 |
| CDK6 | cyclin-dependent kinase 6 | 0.0276792 |
| CAPRIN2 | caprin family member 2 | 0.0269501 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0264663 |
| SOX7 | SRY (sex determining region Y)-box 7 | 0.0262548 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0259687 |
| HDAC9 | histone deacetylase 9 | 0.0258222 |
| CALB1 | calbindin 1, 28kDa | 0.0257128 |
| PLS3 | plastin 3 | 0.0253773 |
| TJP1 | tight junction protein 1 | 0.0253503 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0243931 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0243882 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.024035 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0239585 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0238763 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0236336 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0233999 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0233992 |
| PODXL | podocalyxin-like | 0.0233788 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0230863 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0224165 |
| EXOC6B | exocyst complex component 6B | 0.0224057 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0224015 |
| OXR1 | oxidation resistance 1 | 0.0219302 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0218453 |
| LAMC2 | laminin, gamma 2 | 0.0218351 |
| TGM2 | transglutaminase 2 | 0.0218247 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0214669 |
| VMP1 | vacuole membrane protein 1 | 0.021379 |
| PRSS23 | protease, serine, 23 | 0.0212723 |
| RNF217 | ring finger protein 217 | 0.021249 |
| PCDH1 | protocadherin 1 | 0.0211934 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0210629 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0209879 |
| TXNIP | thioredoxin interacting protein | 0.0209193 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0206038 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.020447 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0204287 |
| RTN4 | reticulon 4 | 0.0199955 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0197949 |
| CORO2A | coronin, actin binding protein, 2A | 0.0197662 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0197002 |
| PALLD | palladin, cytoskeletal associated protein | 0.0196574 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.019397 |
| SETX | senataxin | 0.0193441 |
| PTHLH | parathyroid hormone-like hormone | 0.0192897 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.019129 |
| CD9 | CD9 molecule | 0.0188784 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0188267 |
| ITGA6 | integrin, alpha 6 | 0.0188179 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0187311 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0185015 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0184997 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0182649 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.0182645 |
| MYADM | myeloid-associated differentiation marker | 0.0182547 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MYOF | myoferlin | -0.0901443 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0901057 |
| ANXA1 | annexin A1 | -0.085336 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0729759 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.069785 |
| KIAA1217 | KIAA1217 | -0.0675431 |
| OGA | O-GlcNAcase | -0.0666283 |
| EMP1 | epithelial membrane protein 1 | -0.0656473 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.065625 |
| CD44 | CD44 molecule (Indian blood group) | -0.0627845 |
| GNAS | GNAS complex locus | -0.0572128 |
| MEF2A | myocyte enhancer factor 2A | -0.0561569 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0552148 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0545948 |
| NDRG1 | N-myc downstream regulated 1 | -0.0540375 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0521782 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0515849 |
| H1-0 | H1.0 linker histone | -0.0510839 |
| TMSB4X | thymosin beta 4, X-linked | -0.050559 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.050325 |
| CANX | calnexin | -0.0490672 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0467982 |
| EZR | ezrin | -0.0463664 |
| LMNA | lamin A/C | -0.0459418 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0454475 |
| SMAD3 | SMAD family member 3 | -0.0442384 |
| MORF4L2 | mortality factor 4 like 2 | -0.0439988 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0432672 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0431063 |
| S100A10 | S100 calcium binding protein A10 | -0.042661 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0424509 |
| RPLP1 | ribosomal protein, large, P1 | -0.0413647 |
| RBM39 | RNA binding motif protein 39 | -0.0406213 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.040601 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0394952 |
| RLF | rearranged L-myc fusion | -0.0390694 |
| MTSS1 | metastasis suppressor 1 | -0.039021 |
| ANXA2 | annexin A2 | -0.0388092 |
| PTMA | prothymosin, alpha | -0.0387628 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0382821 |
| RPS6 | ribosomal protein S6 | -0.0359938 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0357386 |
| AHNAK | AHNAK nucleoprotein | -0.0351906 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0335582 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0333905 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0331844 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0330465 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0325021 |
| GOLGA4 | golgin A4 | -0.0324563 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0319654 |
| RPL23 | ribosomal protein L23 | -0.0315694 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0314708 |
| YBX3 | Y box binding protein 3 | -0.0313378 |
| PGK1 | phosphoglycerate kinase 1 | -0.0312824 |
| CUL4B | cullin 4B | -0.0305813 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0299887 |
| TMSB10 | thymosin beta 10 | -0.0298955 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0297282 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0296 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0295252 |
| ARF1 | ADP-ribosylation factor 1 | -0.0291601 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0290676 |
| MED13L | mediator complex subunit 13-like | -0.0289817 |
| SDC4 | syndecan 4 | -0.0288383 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0286263 |
| HELZ | helicase with zinc finger | -0.0282637 |
| SUCO | SUN domain containing ossification factor | -0.0282258 |
| KRT17 | keratin 17, type I | -0.0281495 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.027844 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0275753 |
| FSCN1 | fascin actin-bundling protein 1 | -0.027525 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0275012 |
| ZNF292 | zinc finger protein 292 | -0.0274507 |
| QKI | QKI, KH domain containing, RNA binding | -0.0268873 |
| PRELID2 | PRELI domain containing 2 | -0.0266926 |
| SPAG9 | sperm associated antigen 9 | -0.0266362 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0263366 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0263167 |
| RRBP1 | ribosome binding protein 1 | -0.0258604 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0257479 |
| ANLN | anillin, actin binding protein | -0.0253901 |
| PLEC | plectin | -0.0253134 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0252117 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0248846 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0245187 |
| FAM13A | family with sequence similarity 13, member A | -0.0242226 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | -0.0241773 |
| RPS21 | ribosomal protein S21 | -0.0241193 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0240272 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0238863 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0238125 |
| IER3 | immediate early response 3 | -0.0234985 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | -0.0231636 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0229556 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0228974 |
| FNDC3B | fibronectin type III domain containing 3B | -0.022867 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.022817 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0227412 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0227201 |
| RPS24 | ribosomal protein S24 | -0.0225901 |
