| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Neratinib perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Neratinib_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.11541 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0991119 |
| VMP1 | vacuole membrane protein 1 | 0.060158 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0576664 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0535415 |
| PCBP2 | poly(rC) binding protein 2 | 0.0528836 |
| TXNIP | thioredoxin interacting protein | 0.0502301 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0498452 |
| LOXL3 | lysyl oxidase-like 3 | 0.0495242 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0477437 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0470901 |
| S100A6 | S100 calcium binding protein A6 | 0.0465369 |
| PKM | pyruvate kinase, muscle | 0.0460395 |
| PRDX2 | peroxiredoxin 2 | 0.0457824 |
| LDHA | lactate dehydrogenase A | 0.0449283 |
| WDR43 | WD repeat domain 43 | 0.0441037 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0436449 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0427826 |
| CD47 | CD47 molecule | 0.0417525 |
| TJP1 | tight junction protein 1 | 0.0382904 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0380875 |
| RHOA | ras homolog family member A | 0.0367064 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0366844 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0360551 |
| CALR | calreticulin | 0.034987 |
| EGFR | epidermal growth factor receptor | 0.0341438 |
| SSR1 | signal sequence receptor, alpha | 0.0336782 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.033021 |
| DSTN | destrin (actin depolymerizing factor) | 0.0324348 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0308776 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0308484 |
| MT2A | metallothionein 2A | 0.030501 |
| DUSP4 | dual specificity phosphatase 4 | 0.0300423 |
| ARF4 | ADP-ribosylation factor 4 | 0.0299483 |
| RBM25 | RNA binding motif protein 25 | 0.0295439 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0294873 |
| POTEF | POTE ankyrin domain family, member F | 0.029001 |
| CAVIN2 | caveolae associated protein 2 | 0.0285163 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0284426 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.027416 |
| PDE7B | phosphodiesterase 7B | 0.0273854 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0273343 |
| MLEC | malectin | 0.0268003 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | 0.026632 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0258532 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0258121 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0257487 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0251631 |
| B2M | beta-2-microglobulin | 0.0250601 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0249145 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0248318 |
| ATP5F1A | ATP synthase F1 subunit alpha | 0.0243695 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0241508 |
| CCNL1 | cyclin L1 | 0.0241303 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.0239128 |
| GLI3 | GLI family zinc finger 3 | 0.023591 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | 0.023359 |
| PLXNA2 | plexin A2 | 0.0231548 |
| RNF145 | ring finger protein 145 | 0.0231045 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0229472 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0228243 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0228024 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.022338 |
| PFN1 | profilin 1 | 0.0222984 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0218497 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0218013 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0216113 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0214196 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0212115 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0211742 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0208825 |
| HDLBP | high density lipoprotein binding protein | 0.020754 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | 0.0206843 |
| WASF2 | WAS protein family, member 2 | 0.0206503 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.020551 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.0203694 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa | 0.0200148 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | 0.0197153 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0196265 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0193947 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0193624 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0193254 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0192395 |
| MED13 | mediator complex subunit 13 | 0.0190931 |
| ALKBH5 | AlkB family member 5, RNA demethylase | 0.0190388 |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide | 0.018881 |
| PCBP1 | poly(rC) binding protein 1 | 0.018842 |
| ATXN2 | ataxin 2 | 0.0188061 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.018775 |
| NEBL | nebulette | 0.0185644 |
| HDGF | hepatoma-derived growth factor | 0.0185192 |
| LAMTOR5 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 | 0.0184373 |
| ARF1 | ADP-ribosylation factor 1 | 0.0183506 |
| NUP58 | nucleoporin 58 | 0.0181925 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0181857 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0181405 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 | 0.0181337 |
| VIRMA | vir like m6A methyltransferase associated | 0.0178857 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0178685 |
| TPK1 | thiamin pyrophosphokinase 1 | 0.0178448 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.231888 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.147565 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.116841 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.096463 |
| AHNAK | AHNAK nucleoprotein | -0.0935425 |
| BMP10 | bone morphogenetic protein 10 | -0.0912098 |
| RPS6 | ribosomal protein S6 | -0.0842405 |
| TXNRD1 | thioredoxin reductase 1 | -0.0828209 |
| RPS8 | ribosomal protein S8 | -0.0747578 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0722792 |
| MKI67 | marker of proliferation Ki-67 | -0.0718922 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.070671 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0645232 |
| ACTG1 | actin gamma 1 | -0.0638206 |
| RPLP1 | ribosomal protein, large, P1 | -0.0613335 |
| RPL26 | ribosomal protein L26 | -0.0611891 |
| GLI2 | GLI family zinc finger 2 | -0.0597754 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0588645 |
| RPL9 | ribosomal protein L9 | -0.0585692 |
| CCND1 | cyclin D1 | -0.0565349 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0565238 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0543191 |
| RPL34 | ribosomal protein L34 | -0.0538872 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0512119 |
| FUS | FUS RNA binding protein | -0.0507011 |
| VCL | vinculin | -0.0503199 |
| DIAPH3 | diaphanous-related formin 3 | -0.04807 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0476754 |
| PRELID2 | PRELI domain containing 2 | -0.0457705 |
| RPL35A | ribosomal protein L35a | -0.045396 |
| ANXA1 | annexin A1 | -0.0448315 |
| PDGFC | platelet derived growth factor C | -0.0439459 |
| S100A10 | S100 calcium binding protein A10 | -0.0406267 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.040297 |
| RPS24 | ribosomal protein S24 | -0.0399603 |
| H1-4 | H1.4 linker histone, cluster member | -0.0394552 |
| S100A4 | S100 calcium binding protein A4 | -0.0394286 |
| RPL38 | ribosomal protein L38 | -0.0389988 |
| PTMA | prothymosin, alpha | -0.0389647 |
| RPS2 | ribosomal protein S2 | -0.037874 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.036977 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0366719 |
| RPS21 | ribosomal protein S21 | -0.0361027 |
| FNIP1 | folliculin interacting protein 1 | -0.0353556 |
| APP | amyloid beta (A4) precursor protein | -0.035153 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0350582 |
| RPL12 | ribosomal protein L12 | -0.0344799 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0341287 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.033896 |
| RPS23 | ribosomal protein S23 | -0.033816 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0335416 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0335175 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0334358 |
| ANLN | anillin, actin binding protein | -0.0329101 |
| RPS17 | ribosomal protein S17 | -0.0325818 |
| USP34 | ubiquitin specific peptidase 34 | -0.0325412 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0322211 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0318372 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0314052 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0309514 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0304983 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0304836 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0303396 |
| XPO1 | exportin 1 | -0.030175 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0301383 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0300134 |
| RPL4 | ribosomal protein L4 | -0.0297773 |
| ATP9B | ATPase, class II, type 9B | -0.0297203 |
| MACROD2 | MACRO domain containing 2 | -0.029605 |
| MAP4 | microtubule-associated protein 4 | -0.029517 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0294117 |
| MEF2A | myocyte enhancer factor 2A | -0.0293772 |
| RPL7A | ribosomal protein L7a | -0.0293222 |
| PHF3 | PHD finger protein 3 | -0.0290726 |
| RPL30 | ribosomal protein L30 | -0.0290153 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0287674 |
| HJURP | Holliday junction recognition protein | -0.0287061 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0285606 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0283028 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0281962 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0280346 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0277867 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0276475 |
| FAM162A | family with sequence similarity 162, member A | -0.0269719 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0269376 |
| RPS12 | ribosomal protein S12 | -0.0268374 |
| RPL32 | ribosomal protein L32 | -0.0267862 |
| PDE8A | phosphodiesterase 8A | -0.0267266 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.026466 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0264471 |
| JMJD1C | jumonji domain containing 1C | -0.0264148 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.0263204 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0262384 |
| UBC | ubiquitin C | -0.0261907 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0258485 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0258133 |
| RPL36 | ribosomal protein L36 | -0.0257937 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0255716 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0252616 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0248899 |
