| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Neratinib perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Neratinib_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0914 |
| PTMA | prothymosin, alpha | 0.0420581 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0396021 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0337661 |
| TPX2 | TPX2, microtubule-associated | 0.0322666 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0320274 |
| TMSB10 | thymosin beta 10 | 0.0312074 |
| TXNRD1 | thioredoxin reductase 1 | 0.031136 |
| MYO9A | myosin IXA | 0.0308281 |
| ANLN | anillin, actin binding protein | 0.0301052 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0250714 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0246894 |
| NAV2 | neuron navigator 2 | 0.0245592 |
| UBQLN1 | ubiquilin 1 | 0.024439 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0240801 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0240132 |
| CANX | calnexin | 0.0229343 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0226314 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0225903 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0224678 |
| PHF21A | PHD finger protein 21A | 0.0224021 |
| EXOC5 | exocyst complex component 5 | 0.0223093 |
| CENPF | centromere protein F, 350/400kDa | 0.022026 |
| MAP1B | microtubule-associated protein 1B | 0.0220083 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0216427 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0213058 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0211976 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0208312 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0206315 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0205815 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0205553 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.020468 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0204571 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0203599 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0201777 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0200431 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0200187 |
| KIF5B | kinesin family member 5B | 0.0199812 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.019688 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.019675 |
| CD9 | CD9 molecule | 0.0196703 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.019468 |
| PHF3 | PHD finger protein 3 | 0.0191178 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0189571 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0189521 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0185523 |
| DCP1A | decapping mRNA 1A | 0.0182185 |
| PARD3 | par-3 family cell polarity regulator | 0.0182148 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0181861 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0181578 |
| CPNE8 | copine VIII | 0.0180872 |
| NUP58 | nucleoporin 58 | 0.0180004 |
| NCKAP1 | NCK-associated protein 1 | 0.0176131 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0174771 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0174546 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0174292 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0173171 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0172086 |
| TULP4 | tubby like protein 4 | 0.0171741 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0171516 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0170738 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0170147 |
| RAI1 | retinoic acid induced 1 | 0.0168434 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.01683 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.0168032 |
| PGM3 | phosphoglucomutase 3 | 0.016538 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0165089 |
| DNM2 | dynamin 2 | 0.0163806 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0163536 |
| RAB10 | RAB10, member RAS oncogene family | 0.0163037 |
| CDC27 | cell division cycle 27 | 0.0162349 |
| ATF4 | activating transcription factor 4 | 0.0161892 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0161127 |
| HJURP | Holliday junction recognition protein | 0.0160817 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0159642 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0159177 |
| ATG10 | autophagy related 10 | 0.0157524 |
| ECT2 | epithelial cell transforming 2 | 0.0157436 |
| GAS2L3 | growth arrest-specific 2 like 3 | 0.0156937 |
| NBEAL1 | neurobeachin-like 1 | 0.0156806 |
| SPNS1 | spinster homolog 1 (Drosophila) | 0.0156207 |
| ZNF438 | zinc finger protein 438 | 0.0155972 |
| SERINC1 | serine incorporator 1 | 0.015538 |
| SRPK1 | SRSF protein kinase 1 | 0.0154955 |
| RBM6 | RNA binding motif protein 6 | 0.0154578 |
| PGM2L1 | phosphoglucomutase 2-like 1 | 0.0154209 |
| RHEB | Ras homolog enriched in brain | 0.0153764 |
| MAP4 | microtubule-associated protein 4 | 0.0153312 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0152898 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0152483 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0152058 |
| ANKRD37 | ankyrin repeat domain 37 | 0.015138 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0149851 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0149404 |
| SPAG9 | sperm associated antigen 9 | 0.0148828 |
| RAB21 | RAB21, member RAS oncogene family | 0.0148694 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0147935 |
| STAG2 | stromal antigen 2 | 0.0147728 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.0146752 |
| DIAPH1 | diaphanous-related formin 1 | 0.0146629 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.287785 |
| VIM | vimentin | -0.0787852 |
| SMYD3 | SET and MYND domain containing 3 | -0.062992 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0550271 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0515186 |
| OSMR | oncostatin M receptor | -0.0487722 |
| CD44 | CD44 molecule (Indian blood group) | -0.0479646 |
| GOLGA4 | golgin A4 | -0.0478179 |
| FNDC3B | fibronectin type III domain containing 3B | -0.046384 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0458778 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0434904 |
| RPS6 | ribosomal protein S6 | -0.0422007 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0408345 |
| EXOC6B | exocyst complex component 6B | -0.0401446 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0398373 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0393223 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0392482 |
| NF1 | neurofibromin 1 | -0.0378263 |
| ACTG1 | actin gamma 1 | -0.0373828 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0366277 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0356082 |
| HMGA2 | high mobility group AT-hook 2 | -0.0327247 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0312996 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0305886 |
| FMNL2 | formin-like 2 | -0.0301523 |
| VCL | vinculin | -0.0294991 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0293328 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0291893 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0290807 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0285863 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0284086 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | -0.0283183 |
| RIGI | RNA sensor RIG-I | -0.0278676 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0275678 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0270558 |
| PKM | pyruvate kinase, muscle | -0.0265865 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0262038 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0260281 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0259924 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0258987 |
| SLC36A4 | solute carrier family 36 (proton/amino acid symporter), member 4 | -0.0252878 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0252409 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0248931 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0248266 |
| FUS | FUS RNA binding protein | -0.024634 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.024586 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0243596 |
| RPLP1 | ribosomal protein, large, P1 | -0.0241023 |
| RPL19 | ribosomal protein L19 | -0.0240548 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0227544 |
| IL6ST | interleukin 6 signal transducer | -0.0225238 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0224415 |
| SQSTM1 | sequestosome 1 | -0.0221112 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0218769 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0215779 |
| EGR1 | early growth response 1 | -0.0215715 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0215246 |
| RBM33 | RNA binding motif protein 33 | -0.0213671 |
| RPS27A | ribosomal protein S27a | -0.0211633 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0210205 |
| TMEM263 | transmembrane protein 263 | -0.0208296 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0207943 |
| CWF19L2 | CWF19-like 2, cell cycle control (S. pombe) | -0.0207745 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0205674 |
| RPS13 | ribosomal protein S13 | -0.0204809 |
| NALCN | sodium leak channel, non selective | -0.020441 |
| JMJD1C | jumonji domain containing 1C | -0.0203549 |
| NABP1 | nucleic acid binding protein 1 | -0.0203402 |
| SEC24D | SEC24 family member D | -0.0201635 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0200059 |
| RPS25 | ribosomal protein S25 | -0.0199982 |
| OLA1 | Obg-like ATPase 1 | -0.0198229 |
| GPHN | gephyrin | -0.0198198 |
| EVI5 | ecotropic viral integration site 5 | -0.0194063 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0193999 |
| S100A10 | S100 calcium binding protein A10 | -0.0193387 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.01926 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0191858 |
| UBB | ubiquitin B | -0.0191375 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0190654 |
| RPL11 | ribosomal protein L11 | -0.0189485 |
| GNAS | GNAS complex locus | -0.0189121 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0189036 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0187647 |
| MYO9B | myosin IXB | -0.0187591 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0186612 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0185401 |
| SIK3 | SIK family kinase 3 | -0.0184712 |
| HMGB1 | high mobility group box 1 | -0.018433 |
| RPL35 | ribosomal protein L35 | -0.0184284 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0184146 |
| MSN | moesin | -0.0184125 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0183987 |
| PHF14 | PHD finger protein 14 | -0.0183353 |
| RPS29 | ribosomal protein S29 | -0.01829 |
| RSU1 | Ras suppressor protein 1 | -0.0181846 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0181676 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0181233 |
| ERBIN | erbb2 interacting protein | -0.0181206 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0181186 |
