Nerve Degeneration Gene Set
Genes
32 genes associated with the Nerve Degeneration phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.
| Symbol |
Name |
|
ACE
|
angiotensin I converting enzyme
|
|
APOE
|
apolipoprotein E
|
|
APP
|
amyloid beta (A4) precursor protein
|
|
ATXN2
|
ataxin 2
|
|
BACE1
|
beta-site APP-cleaving enzyme 1
|
|
CDKN2B-AS1
|
CDKN2B antisense RNA 1
|
|
CNR1
|
cannabinoid receptor 1 (brain)
|
|
COX1
|
|
|
CYP2D6
|
cytochrome P450, family 2, subfamily D, polypeptide 6
|
|
DHFR
|
dihydrofolate reductase
|
|
GAPDH
|
glyceraldehyde-3-phosphate dehydrogenase
|
|
GRIN2B
|
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
|
|
GSK3A
|
glycogen synthase kinase 3 alpha
|
|
HFE
|
hemochromatosis
|
|
IL1A
|
interleukin 1, alpha
|
|
IL1B
|
interleukin 1, beta
|
|
KIF5A
|
kinesin family member 5A
|
|
MAPT
|
microtubule-associated protein tau
|
|
MT-ND2
|
MTND2
|
|
MTHFR
|
methylenetetrahydrofolate reductase (NAD(P)H)
|
|
NINJ1
|
ninjurin 1
|
|
PARK2
|
parkin RBR E3 ubiquitin protein ligase
|
|
PITX3
|
paired-like homeodomain 3
|
|
SIX1
|
SIX homeobox 1
|
|
SIX6
|
SIX homeobox 6
|
|
SMN1
|
survival of motor neuron 1, telomeric
|
|
SMN2
|
survival of motor neuron 2, centromeric
|
|
SNCA
|
synuclein, alpha (non A4 component of amyloid precursor)
|
|
SOD1
|
superoxide dismutase 1, soluble
|
|
SORL1
|
sortilin-related receptor, L(DLR class) A repeats containing
|
|
UBQLN1
|
ubiquilin 1
|
|
WFS1
|
Wolfram syndrome 1 (wolframin)
|
