Neuritis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
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Genes

383 genes co-occuring with the disease Neuritis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
NGF nerve growth factor (beta polypeptide) 2.483
PMP2 peripheral myelin protein 2 2.449
SNCA synuclein, alpha (non A4 component of amyloid precursor) 2.418
MBP myelin basic protein 2.408
MOG myelin oligodendrocyte glycoprotein 2.379
IFNG interferon, gamma 2.378
CD4 CD4 molecule 2.357
TNF tumor necrosis factor 2.335
IL6 interleukin 6 2.326
IL1B interleukin 1, beta 2.301
APP amyloid beta (A4) precursor protein 2.3
BDNF brain-derived neurotrophic factor 2.265
IL10 interleukin 10 2.226
IL17A interleukin 17A 2.131
IL4 interleukin 4 2.118
NFASC neurofascin 2.084
GLDN gliomedin 2.081
CD8A CD8a molecule 2.02
GDNF glial cell derived neurotrophic factor 2.0
FOXP3 forkhead box P3 1.972
AIF1 allograft inflammatory factor 1 1.965
MAPT microtubule-associated protein tau 1.96
MAG myelin associated glycoprotein 1.957
TGFB1 transforming growth factor, beta 1 1.942
GFAP glial fibrillary acidic protein 1.94
ALB albumin 1.916
CCL2 chemokine (C-C motif) ligand 2 1.909
MAP2 microtubule-associated protein 2 1.904
IL2 interleukin 2 1.9
TLR4 toll-like receptor 4 1.886
TARDBP TAR DNA binding protein 1.875
INS insulin 1.855
NEFL neurofilament, light polypeptide 1.827
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 1.82
TAC1 tachykinin, precursor 1 1.816
PXDN peroxidasin 1.816
BACE1 beta-site APP-cleaving enzyme 1 1.814
PXDNL peroxidasin-like 1.813
CRP C-reactive protein, pentraxin-related 1.812
GAP43 growth associated protein 43 1.811
TH tyrosine hydroxylase 1.809
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.792
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.779
APOE apolipoprotein E 1.775
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 1.774
CNTNAP1 contactin associated protein 1 1.772
PSEN1 presenilin 1 1.771
SEPTIN9 septin 9 1.765
IL1A interleukin 1, alpha 1.762
LRRK2 leucine-rich repeat kinase 2 1.761
CD86 CD86 molecule 1.756
CXCL10 chemokine (C-X-C motif) ligand 10 1.745
CD68 CD68 molecule 1.733
TLR2 toll-like receptor 2 1.723
SYP synaptophysin 1.72
IFNB1 interferon, beta 1, fibroblast 1.718
PRKN parkin RBR E3 ubiquitin protein ligase 1.717
DLG4 discs, large homolog 4 (Drosophila) 1.714
S100B S100 calcium binding protein B 1.707
TRPV1 transient receptor potential cation channel, subfamily V, member 1 1.699
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.699
FGF2 fibroblast growth factor 2 (basic) 1.695
CXCL8 chemokine (C-X-C motif) ligand 8 1.692
PINK1 PTEN induced putative kinase 1 1.691
ACTB actin, beta 1.688
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.686
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.682
JUN jun proto-oncogene 1.68
IL18 interleukin 18 1.662
GSK3B glycogen synthase kinase 3 beta 1.662
NES nestin 1.659
ICAM1 intercellular adhesion molecule 1 1.647
CCL3 chemokine (C-C motif) ligand 3 1.643
CX3CR1 chemokine (C-X3-C motif) receptor 1 1.641
HMOX1 heme oxygenase 1 1.639
NEFH neurofilament, heavy polypeptide 1.633
NTF3 neurotrophin 3 1.628
CREB1 cAMP responsive element binding protein 1 1.626
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.613
PARK7 parkinson protein 7 1.613
BCL2 B-cell CLL/lymphoma 2 1.61
MMP9 matrix metallopeptidase 9 1.608
ACHE acetylcholinesterase (Yt blood group) 1.607
NGFR nerve growth factor receptor 1.605
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 1.591
CCL5 chemokine (C-C motif) ligand 5 1.588
CNTF ciliary neurotrophic factor 1.583
SYN1 synapsin I 1.577
CDK5 cyclin-dependent kinase 5 1.577
IL9 interleukin 9 1.568
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.567
IL13 interleukin 13 1.565
CHAT choline O-acetyltransferase 1.562
PMP22 peripheral myelin protein 22 1.56
IL5 interleukin 5 1.552
ACE2 angiotensin I converting enzyme 2 1.551
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.543
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.542
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.54
CYCS cytochrome c, somatic 1.539
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.538
SOD1 superoxide dismutase 1, soluble 1.537
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.536
CNTN1 contactin 1 1.527
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.517
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.516
CCNDBP1 cyclin D-type binding-protein 1 1.515
CD80 CD80 molecule 1.508
MYD88 myeloid differentiation primary response 88 1.506
NLRP3 NLR family, pyrin domain containing 3 1.505
CCR2 chemokine (C-C motif) receptor 2 1.499
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 1.489
FN1 fibronectin 1 1.484
IDE insulin-degrading enzyme 1.477
PTPRC protein tyrosine phosphatase, receptor type, C 1.468
MAPK3 mitogen-activated protein kinase 3 1.459
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.454
IFNA1 interferon, alpha 1 1.446
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 1.443
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.442
HTT huntingtin 1.442
CD28 CD28 molecule 1.439
IGF1 insulin-like growth factor 1 (somatomedin C) 1.435
FOS FBJ murine osteosarcoma viral oncogene homolog 1.43
DPYSL5 dihydropyrimidinase-like 5 1.427
TLR1 toll-like receptor 1 1.427
TBX21 T-box 21 1.425
THY1 Thy-1 cell surface antigen 1.421
EGF epidermal growth factor 1.409
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.407
CD40 CD40 molecule, TNF receptor superfamily member 5 1.407
CXCL13 chemokine (C-X-C motif) ligand 13 1.404
BCHE butyrylcholinesterase 1.404
VCAM1 vascular cell adhesion molecule 1 1.403
CKM creatine kinase, muscle 1.398
BAX BCL2-associated X protein 1.397
SCN9A sodium channel, voltage gated, type IX alpha subunit 1.397
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase 1.396
PSEN2 presenilin 2 1.393
CKB creatine kinase, brain 1.393
PRX periaxin 1.392
IL22 interleukin 22 1.392
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1.391
CKMT1B creatine kinase, mitochondrial 1B 1.39
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1.384
C9ORF72 chromosome 9 open reading frame 72 1.376
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.374
TLR9 toll-like receptor 9 1.373
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.363
TREM2 triggering receptor expressed on myeloid cells 2 1.362
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.361
FGF8 fibroblast growth factor 8 (androgen-induced) 1.356
MPZL1 myelin protein zero-like 1 1.353
SIRT1 sirtuin 1 1.349
SNCG synuclein, gamma (breast cancer-specific protein 1) 1.347
RHOA ras homolog family member A 1.347
CCL4 chemokine (C-C motif) ligand 4 1.346
POMC proopiomelanocortin 1.342
SCN8A sodium channel, voltage gated, type VIII alpha subunit 1.336
NCAM1 neural cell adhesion molecule 1 1.335
FUS FUS RNA binding protein 1.326
NFE2L2 nuclear factor, erythroid 2-like 2 1.323
CXCL12 chemokine (C-X-C motif) ligand 12 1.323
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.323
ACE angiotensin I converting enzyme 1.322
GALC galactosylceramidase 1.315
OR4F29 olfactory receptor, family 4, subfamily F, member 29 1.315
MPO myeloperoxidase 1.314
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.312
TP53 tumor protein p53 1.309
CXCR3 chemokine (C-X-C motif) receptor 3 1.308
GPX8 glutathione peroxidase 8 (putative) 1.306
ATP13A2 ATPase type 13A2 1.306
HSPA4 heat shock 70kDa protein 4 1.302
GPX6 glutathione peroxidase 6 1.3
SCN10A sodium channel, voltage gated, type X alpha subunit 1.299
FGF17 fibroblast growth factor 17 1.298
GPX5 glutathione peroxidase 5 1.298
NTF4 neurotrophin 4 1.296
SYN2 synapsin II 1.295
GPX7 glutathione peroxidase 7 1.295
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.294
GPX2 glutathione peroxidase 2 1.293
MUSK muscle, skeletal, receptor tyrosine kinase 1.292
FGF20 fibroblast growth factor 20 1.292
TRPA1 transient receptor potential cation channel, subfamily A, member 1 1.289
DPYSL2 dihydropyrimidinase-like 2 1.284
GPX3 glutathione peroxidase 3 1.284
MAOB monoamine oxidase B 1.284
FGF10 fibroblast growth factor 10 1.283
FGF3 fibroblast growth factor 3 1.281
MARVELD1 MARVEL domain containing 1 1.278
SOX10 SRY (sex determining region Y)-box 10 1.272
C3 complement component 3 1.269
PPARG peroxisome proliferator-activated receptor gamma 1.266
OLIG2 oligodendrocyte lineage transcription factor 2 1.265
FGF4 fibroblast growth factor 4 1.262
FGF16 fibroblast growth factor 16 1.26
FGF6 fibroblast growth factor 6 1.26
FGF7 fibroblast growth factor 7 1.258
FGF22 fibroblast growth factor 22 1.253
FGF5 fibroblast growth factor 5 1.252
MAP1B microtubule-associated protein 1B 1.244
FGF9 fibroblast growth factor 9 1.243
FGF18 fibroblast growth factor 18 1.243
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 1.242
EPO erythropoietin 1.241
MRC1 mannose receptor, C type 1 1.238
NRG1 neuregulin 1 1.237
SNAP25 synaptosomal-associated protein, 25kDa 1.236
SYN3 synapsin III 1.235
CNTNAP2 contactin associated protein-like 2 1.235
LTA lymphotoxin alpha 1.23
CLDN5 claudin 5 1.228
CD19 CD19 molecule 1.227
OPTN optineurin 1.227
CDC42 cell division cycle 42 1.222
MAOA monoamine oxidase A 1.22
MMEL1 membrane metallo-endopeptidase-like 1 1.217
HMGB1 high mobility group box 1 1.212
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 1.211
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.205
SELL selectin L 1.204
BECN1 beclin 1, autophagy related 1.201
PPP1R3A protein phosphatase 1, regulatory subunit 3A 1.199
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) 1.198
FASLG Fas ligand (TNF superfamily, member 6) 1.194
DNAH8 dynein, axonemal, heavy chain 8 1.192
CD44 CD44 molecule (Indian blood group) 1.192
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 1.19
SQSTM1 sequestosome 1 1.187
DCX doublecortin 1.184
ARTN artemin 1.183
STAT1 signal transducer and activator of transcription 1, 91kDa 1.183
CD276 CD276 molecule 1.181
TLR3 toll-like receptor 3 1.179
RORC RAR-related orphan receptor C 1.179
JAK2 Janus kinase 2 1.179
GPR32 G protein-coupled receptor 32 1.178
SNCAIP synuclein, alpha interacting protein 1.178
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.174
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.174
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 1.174
MME membrane metallo-endopeptidase 1.172
MAPK8 mitogen-activated protein kinase 8 1.171
CXCR4 chemokine (C-X-C motif) receptor 4 1.169
CXCL9 chemokine (C-X-C motif) ligand 9 1.169
CSF3 colony stimulating factor 3 (granulocyte) 1.169
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.168
BIN1 bridging integrator 1 1.168
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) 1.164
BCL2L1 BCL2-like 1 1.16
SOX1 SRY (sex determining region Y)-box 1 1.159
ARG1 arginase 1 1.155
IL17F interleukin 17F 1.154
S1PR5 sphingosine-1-phosphate receptor 5 1.152
TUBB3 tubulin, beta 3 class III 1.15
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.149
CD274 CD274 molecule 1.149
NRCAM neuronal cell adhesion molecule 1.146
GOLGA6L6 golgin A6 family-like 6 1.146
PAX6 paired box 6 1.145
ISL1 ISL LIM homeobox 1 1.141
PDCD1 programmed cell death 1 1.141
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.14
CCDC122 coiled-coil domain containing 122 1.139
NOS2 nitric oxide synthase 2, inducible 1.138
PRTN3 proteinase 3 1.138
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 1.137
TLR6 toll-like receptor 6 1.135
POU4F1 POU class 4 homeobox 1 1.133
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 1.129
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 1.127
CD40LG CD40 ligand 1.125
IL1R1 interleukin 1 receptor, type I 1.125
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 1.124
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.123
IL15 interleukin 15 1.121
SELE selectin E 1.114
FGF13 fibroblast growth factor 13 1.114
GATA3 GATA binding protein 3 1.114
ICOS inducible T-cell co-stimulator 1.11
AMPH amphiphysin 1.109
IDO1 indoleamine 2,3-dioxygenase 1 1.108
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 1.108
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 1.108
MYH14 myosin, heavy chain 14, non-muscle 1.105
PTRHD1 peptidyl-tRNA hydrolase domain containing 1 1.104
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.104
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.103
SHTN1 shootin 1 1.101
NTN1 netrin 1 1.101
ENO2 enolase 2 (gamma, neuronal) 1.101
NCSTN nicastrin 1.101
OCLN occludin 1.097
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.097
GRIA1 glutamate receptor, ionotropic, AMPA 1 1.096
S1PR3 sphingosine-1-phosphate receptor 3 1.096
PRNP prion protein 1.093
NRTN neurturin 1.093
IFNA2 interferon, alpha 2 1.089
KEAP1 kelch-like ECH-associated protein 1 1.089
LGI1 leucine-rich, glioma inactivated 1 1.088
EGR2 early growth response 2 1.088
MMP3 matrix metallopeptidase 3 1.088
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.087
TJP1 tight junction protein 1 1.084
PLP1 proteolipid protein 1 1.083
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 1.083
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 1.082
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 1.08
RAG1 recombination activating gene 1 1.079
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 1.075
CALML3 calmodulin-like 3 1.075
CALML5 calmodulin-like 5 1.074
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 1.071
CSF1 colony stimulating factor 1 (macrophage) 1.071
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 1.07
SOX2 SRY (sex determining region Y)-box 2 1.069
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 1.069
IL33 interleukin 33 1.069
SPP1 secreted phosphoprotein 1 1.067
MFN2 mitofusin 2 1.065
CCR1 chemokine (C-C motif) receptor 1 1.065
CALML4 calmodulin-like 4 1.064
RTN3 reticulon 3 1.064
CALML6 calmodulin-like 6 1.064
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 1.064
KNG1 kininogen 1 1.063
VIP vasoactive intestinal peptide 1.062
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.06
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 1.059
COCH cochlin 1.058
RBP3 retinol binding protein 3, interstitial 1.058
DCTN1 dynactin 1 1.058
PTN pleiotrophin 1.058
SNCB synuclein, beta 1.056
PRPH peripherin 1.055
OR4F16 olfactory receptor, family 4, subfamily F, member 16 1.054
DEFB110 defensin, beta 110 1.054
NOS1 nitric oxide synthase 1 (neuronal) 1.054
CCK cholecystokinin 1.053
SPTBN4 spectrin, beta, non-erythrocytic 4 1.052
GRN granulin 1.051
ATF3 activating transcription factor 3 1.048
CALB1 calbindin 1, 28kDa 1.048
TBK1 TANK-binding kinase 1 1.045
RTN4 reticulon 4 1.045
TSPO translocator protein (18kDa) 1.043
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.041
FYN FYN proto-oncogene, Src family tyrosine kinase 1.037
ATG5 autophagy related 5 1.035
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 1.035
DES desmin 1.035
TRPC4 transient receptor potential cation channel, subfamily C, member 4 1.034
EGFR epidermal growth factor receptor 1.032
TLR7 toll-like receptor 7 1.031
GSR glutathione reductase 1.03
TTR transthyretin 1.028
TRPC1 transient receptor potential cation channel, subfamily C, member 1 1.027
NOD2 nucleotide-binding oligomerization domain containing 2 1.026
LINGO1 leucine rich repeat and Ig domain containing 1 1.025
IL7 interleukin 7 1.025
SCN11A sodium channel, voltage gated, type XI alpha subunit 1.024
FRMD7 FERM domain containing 7 1.022
FPR2 formyl peptide receptor 2 1.022
SCRT1 scratch family zinc finger 1 1.022
NELFCD negative elongation factor complex member C/D 1.019
IDO2 indoleamine 2,3-dioxygenase 2 1.019
CCL11 chemokine (C-C motif) ligand 11 1.018
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 1.017
SPON1 spondin 1, extracellular matrix protein 1.016
NRBF2 nuclear receptor binding factor 2 1.014
UBQLN2 ubiquilin 2 1.013
DNTT DNA nucleotidylexotransferase 1.011
ERVW-1 endogenous retrovirus group W, member 1 1.01
RTN4R reticulon 4 receptor 1.01
NEUROD1 neuronal differentiation 1 1.009
CD163 CD163 molecule 1.009
TFRC transferrin receptor 1.008
PSENEN presenilin enhancer gamma secretase subunit 1.006
F2R coagulation factor II (thrombin) receptor 1.006
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 1.001