Neurofilament Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores 2025
Category structural or functional annotations
Type cellular component
Description A type of intermediate filament found in the core of neuronal axons. Neurofilaments are heteropolymers composed of three type IV polypeptides: NF-L, NF-M, and NF-H (for low, middle, and high molecular weight). Neurofilaments are responsible for the radial growth of an axon and determine axonal diameter. (Gene Ontology, GO_0005883)
External Link http://amigo.geneontology.org/amigo/term/GO:0005883
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Genes

7 proteins localized to the Neurofilament cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

Symbol Name Standardized Value
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 5.0
NEFL neurofilament, light polypeptide 5.0
NEFM neurofilament, medium polypeptide 4.0
INA internexin neuronal intermediate filament protein, alpha 4.0
CLDN11 claudin 11 4.0
NEFH neurofilament, heavy polypeptide 3.0
LDLRAP1 low density lipoprotein receptor adaptor protein 1 3.0