| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| Description | A polypeptide that has formula C50H80N14O14S. (Chemical Entities of Biological Interest Ontology, CHEBI_80311) |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/5311311 |
| Similar Terms | |
| Downloads & Tools |
200 proteins with high or low expression in Neurokinin A relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DES | desmin | 4.66 |
| BAHCC1 | BAH domain and coiled-coil containing 1 | 1.42 |
| FDXACB1 | ferredoxin-fold anticodon binding domain containing 1 | 1.22 |
| DMD | dystrophin | 1.06 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 1.02 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.8 |
| C12ORF60 | chromosome 12 open reading frame 60 | 0.66 |
| ZNF91 | zinc finger protein 91 | 0.61 |
| MYO10 | myosin X | 0.59 |
| FAS | Fas cell surface death receptor | 0.56 |
| NKX2-8 | NK2 homeobox 8 | 0.55 |
| LRIG3 | leucine-rich repeats and immunoglobulin-like domains 3 | 0.55 |
| LRP1 | low density lipoprotein receptor-related protein 1 | 0.54 |
| MDM4 | MDM4, p53 regulator | 0.52 |
| FANCC | Fanconi anemia, complementation group C | 0.48 |
| MTUS2 | microtubule associated tumor suppressor candidate 2 | 0.47 |
| ADK | adenosine kinase | 0.47 |
| BCL2L12 | BCL2-like 12 (proline rich) | 0.47 |
| MYZAP | myocardial zonula adherens protein | 0.46 |
| LRRC46 | leucine rich repeat containing 46 | 0.46 |
| ZNF14 | zinc finger protein 14 | 0.46 |
| ZHX1 | zinc fingers and homeoboxes 1 | 0.46 |
| ZFPM1 | zinc finger protein, FOG family member 1 | 0.45 |
| SPC24 | SPC24, NDC80 kinetochore complex component | 0.45 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.44 |
| JPT1 | Jupiter microtubule associated homolog 1 | 0.44 |
| EHF | ets homologous factor | 0.42 |
| COA4 | cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) | 0.42 |
| SLC26A11 | solute carrier family 26 (anion exchanger), member 11 | 0.42 |
| ZNF557 | zinc finger protein 557 | 0.42 |
| EMC2 | ER membrane protein complex subunit 2 | 0.41 |
| HGH1 | HGH1 homolog (S. cerevisiae) | 0.41 |
| CD320 | CD320 molecule | 0.41 |
| GRHL1 | grainyhead-like 1 (Drosophila) | 0.39 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | 0.39 |
| PHLPP2 | PH domain and leucine rich repeat protein phosphatase 2 | 0.38 |
| REX1BD | required for excision 1-B domain containing | 0.38 |
| RCAN1 | regulator of calcineurin 1 | 0.38 |
| DNAH1 | dynein, axonemal, heavy chain 1 | 0.37 |
| BBS1 | Bardet-Biedl syndrome 1 | 0.37 |
| CPTP | ceramide-1-phosphate transfer protein | 0.37 |
| TIMM8B | translocase of inner mitochondrial membrane 8 homolog B (yeast) | 0.37 |
| POLE4 | polymerase (DNA-directed), epsilon 4, accessory subunit | 0.36 |
| RNF141 | ring finger protein 141 | 0.36 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | 0.35 |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 | 0.35 |
| RAD9A | RAD9 homolog A (S. pombe) | 0.35 |
| BRK1 | BRICK1, SCAR/WAVE actin-nucleating complex subunit | 0.35 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 | 0.34 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 | 0.34 |
| UQCRH | ubiquinol-cytochrome c reductase hinge protein | 0.34 |
| OGG1 | 8-oxoguanine DNA glycosylase | 0.33 |
| REPS2 | RALBP1 associated Eps domain containing 2 | 0.33 |
| KMT2B | lysine (K)-specific methyltransferase 2B | 0.33 |
| SNAI1 | snail family zinc finger 1 | 0.33 |
| RNF7 | ring finger protein 7 | 0.33 |
| ARL6IP6 | ADP-ribosylation factor-like 6 interacting protein 6 | 0.33 |
| FBXL3 | F-box and leucine-rich repeat protein 3 | 0.33 |
| ALK | anaplastic lymphoma receptor tyrosine kinase | 0.32 |
| HOXA9 | homeobox A9 | 0.32 |
| FANCF | Fanconi anemia, complementation group F | 0.31 |
| TEDC2 | tubulin epsilon and delta complex 2 | 0.31 |
| PTMA | prothymosin, alpha | 0.31 |
| SRPX | sushi-repeat containing protein, X-linked | 0.31 |
| S100PBP | S100P binding protein | 0.31 |
| KIAA0586 | KIAA0586 | 0.31 |
| PROSER3 | proline and serine rich 3 | 0.31 |
| MED8 | mediator complex subunit 8 | 0.31 |
| TP73 | tumor protein p73 | 0.31 |
| ABCD1 | ATP-binding cassette, sub-family D (ALD), member 1 | 0.31 |
| HAUS7 | HAUS augmin-like complex, subunit 7 | 0.31 |
| FANCL | Fanconi anemia, complementation group L | 0.31 |
| RPL26 | ribosomal protein L26 | 0.3 |
| ARL14EPL | ADP-ribosylation factor-like 14 effector protein-like | 0.3 |
| BTN2A1 | butyrophilin, subfamily 2, member A1 | 0.3 |
| VWA1 | von Willebrand factor A domain containing 1 | 0.3 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.3 |
| TRIM62 | tripartite motif containing 62 | 0.3 |
| VIM | vimentin | 0.3 |
| IER2 | immediate early response 2 | 0.3 |
| TTN | titin | 0.3 |
| CR2 | complement component (3d/Epstein Barr virus) receptor 2 | 0.3 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | 0.29 |
| GLRX5 | glutaredoxin 5 | 0.29 |
| ZNF543 | zinc finger protein 543 | 0.29 |
| ODC1 | ornithine decarboxylase 1 | 0.29 |
| PRXL2C | peroxiredoxin like 2C | 0.29 |
| HSP90AB3P | heat shock protein 90kDa alpha (cytosolic), class B member 3, pseudogene | 0.29 |
| ZNF827 | zinc finger protein 827 | 0.29 |
| ZCCHC2 | zinc finger, CCHC domain containing 2 | 0.29 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like | 0.29 |
| TIMM8A | translocase of inner mitochondrial membrane 8 homolog A (yeast) | 0.29 |
| TTC8 | tetratricopeptide repeat domain 8 | 0.29 |
| MIF | macrophage migration inhibitory factor (glycosylation-inhibiting factor) | 0.29 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.29 |
| HSBP1 | heat shock factor binding protein 1 | 0.29 |
| C2CD2L | C2CD2-like | 0.28 |
| ATXN7L3B | ataxin 7-like 3B | 0.28 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.28 |
| CUTA | cutA divalent cation tolerance homolog (E. coli) | 0.28 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MDM1 | Mdm1 nuclear protein homolog (mouse) | -2.65 |
| HMOX1 | heme oxygenase 1 | -0.84 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 | -0.82 |
| PAQR7 | progestin and adipoQ receptor family member VII | -0.73 |
| ZNF564 | zinc finger protein 564 | -0.66 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.63 |
| HIST2H2AA3 | histone cluster 2, H2aa3 | -0.62 |
| SQSTM1 | sequestosome 1 | -0.62 |
| DCAF5 | DDB1 and CUL4 associated factor 5 | -0.59 |
| ABHD4 | abhydrolase domain containing 4 | -0.57 |
| TCP11L1 | t-complex 11, testis-specific-like 1 | -0.56 |
| ANKRD46 | ankyrin repeat domain 46 | -0.55 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 | -0.5 |
| PCMTD1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 | -0.49 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 | -0.46 |
| TMEM120A | transmembrane protein 120A | -0.45 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 | -0.45 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.44 |
| DBNL | drebrin-like | -0.43 |
| GDF15 | growth differentiation factor 15 | -0.38 |
| CCDC158 | coiled-coil domain containing 158 | -0.37 |
| ACTBL2 | actin, beta-like 2 | -0.37 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.36 |
| E4F1 | E4F transcription factor 1 | -0.36 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | -0.35 |
| ADCK1 | aarF domain containing kinase 1 | -0.35 |
| C4BPA | complement component 4 binding protein, alpha | -0.35 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.34 |
| PLEKHA3 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3 | -0.34 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.34 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.34 |
| NTN1 | netrin 1 | -0.33 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | -0.33 |
| RARG | retinoic acid receptor, gamma | -0.33 |
| LMLN | leishmanolysin-like (metallopeptidase M8 family) | -0.33 |
| TTC9 | tetratricopeptide repeat domain 9 | -0.33 |
| SMAP1 | small ArfGAP 1 | -0.3 |
| PCDH1 | protocadherin 1 | -0.3 |
| SSH2 | slingshot protein phosphatase 2 | -0.3 |
| SH3D19 | SH3 domain containing 19 | -0.3 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic | -0.3 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.3 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) | -0.29 |
| RASSF5 | Ras association (RalGDS/AF-6) domain family member 5 | -0.29 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.29 |
| FAM241B | family with sequence similarity 241 member B | -0.29 |
| FHIT | fragile histidine triad | -0.28 |
| HMCN1 | hemicentin 1 | -0.28 |
| TUFT1 | tuftelin 1 | -0.28 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.28 |
| IRS2 | insulin receptor substrate 2 | -0.27 |
| CCDC28A | coiled-coil domain containing 28A | -0.27 |
| CARD10 | caspase recruitment domain family, member 10 | -0.27 |
| FGF19 | fibroblast growth factor 19 | -0.27 |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G | -0.26 |
| PSMC1 | proteasome (prosome, macropain) 26S subunit, ATPase, 1 | -0.26 |
| ACVR2A | activin A receptor, type IIA | -0.26 |
| FN1 | fibronectin 1 | -0.26 |
| PRG4 | proteoglycan 4 | -0.26 |
| DST | dystonin | -0.26 |
| HMGN4 | high mobility group nucleosomal binding domain 4 | -0.26 |
| SERINC1 | serine incorporator 1 | -0.25 |
| SRD5A3 | steroid 5 alpha-reductase 3 | -0.25 |
| ZYX | zyxin | -0.25 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.25 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.25 |
| HECW2 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 | -0.25 |
| SPNS1 | spinster homolog 1 (Drosophila) | -0.25 |
| FOXJ2 | forkhead box J2 | -0.24 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.24 |
| CHMP1B | charged multivesicular body protein 1B | -0.24 |
| VAMP8 | vesicle-associated membrane protein 8 | -0.24 |
| NEDD8 | neural precursor cell expressed, developmentally down-regulated 8 | -0.23 |
| KDF1 | keratinocyte differentiation factor 1 | -0.23 |
| RAD51D | RAD51 paralog D | -0.23 |
| GPATCH2L | G patch domain containing 2-like | -0.23 |
| MLH3 | mutL homolog 3 | -0.23 |
| CCNT2 | cyclin T2 | -0.23 |
| HECA | headcase homolog (Drosophila) | -0.23 |
| MED30 | mediator complex subunit 30 | -0.23 |
| LRP6 | low density lipoprotein receptor-related protein 6 | -0.23 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.23 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.23 |
| ANKRD20A4 | ankyrin repeat domain 20 family, member A4 | -0.22 |
| MSMO1 | methylsterol monooxygenase 1 | -0.22 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | -0.22 |
| DNLZ | DNL-type zinc finger | -0.22 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | -0.22 |
| GGT2 | gamma-glutamyltransferase 2 | -0.22 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.22 |
| NPDC1 | neural proliferation, differentiation and control, 1 | -0.22 |
| UQCC2 | ubiquinol-cytochrome c reductase complex assembly factor 2 | -0.22 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.22 |
| CYBA | cytochrome b-245, alpha polypeptide | -0.22 |
| CBR3 | carbonyl reductase 3 | -0.22 |
| JOSD1 | Josephin domain containing 1 | -0.21 |
| EPDR1 | ependymin related 1 | -0.21 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.21 |
| LINGO1 | leucine rich repeat and Ig domain containing 1 | -0.21 |
| ALG14 | ALG14, UDP-N-acetylglucosaminyltransferase subunit | -0.21 |
