Neuroticism Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description disease cluster belonging to disease group psych (Genetic Association Database)
External Link https://www.disgenet.org/browser/0/1/0/C1842981
Similar Terms
Downloads & Tools

Genes

134 genes associated with the disease Neuroticism in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACE angiotensin I converting enzyme
ADSL adenylosuccinate lyase
ANKK1 ankyrin repeat and kinase domain containing 1
APOE apolipoprotein E
AR androgen receptor
ARR3 arrestin 3, retinal (X-arrestin)
ARSI arylsulfatase family, member I
ASCL1 achaete-scute family bHLH transcription factor 1
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATP7A ATPase, Cu++ transporting, alpha polypeptide
AVPR1A arginine vasopressin receptor 1A
AZU1 azurocidin 1
BDNF brain-derived neurotrophic factor
BLK BLK proto-oncogene, Src family tyrosine kinase
BPNT2 3'(2'), 5'-bisphosphate nucleotidase 2
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CASR calcium-sensing receptor
CCDC6 coiled-coil domain containing 6
CCHCR1 coiled-coil alpha-helical rod protein 1
CD38 CD38 molecule
CDH13 cadherin 13
CDH23 cadherin-related 23
CDK6 cyclin-dependent kinase 6
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CLU clusterin
CNR1 cannabinoid receptor 1 (brain)
CNTNAP2 contactin associated protein-like 2
COMT catechol-O-methyltransferase
CRHR1 corticotropin releasing hormone receptor 1
CRP C-reactive protein, pentraxin-related
CSTB cystatin B (stefin B)
CXADR coxsackie virus and adenovirus receptor
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DNAH8 dynein, axonemal, heavy chain 8
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
DTNBP1 dystrobrevin binding protein 1
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
F9 coagulation factor IX
FKBP5 FK506 binding protein 5
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GPC6 glypican 6
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRM7 glutamate receptor, metabotropic 7
GYPA glycophorin A (MNS blood group)
HIST1H2BH histone cluster 1, H2bh
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
IFNG interferon, gamma
IL10 interleukin 10
IL13 interleukin 13
IL2 interleukin 2
IL4 interleukin 4
IL5 interleukin 5
IL6 interleukin 6
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITK IL2-inducible T-cell kinase
KANSL1 KAT8 regulatory NSL complex subunit 1
KLHL2 kelch-like family member 2
KRT7 keratin 7, type II
L1CAM L1 cell adhesion molecule
L3MBTL2 l(3)mbt-like 2 (Drosophila)
LCE3C late cornified envelope 3C
LMO4 LIM domain only 4
LRRC57 leucine rich repeat containing 57
LTA lymphotoxin alpha
LXN latexin
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAOA monoamine oxidase A
MCIDAS multiciliate differentiation and DNA synthesis associated cell cycle protein
MCPH1 microcephalin 1
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MSRA methionine sulfoxide reductase A
MTA2 metastasis associated 1 family, member 2
MTCL1 microtubule crosslinking factor 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NF2 neurofibromin 2 (merlin)
NKAIN2 Na+/K+ transporting ATPase interacting 2
NOS1 nitric oxide synthase 1 (neuronal)
NPY neuropeptide Y
NR1I3 nuclear receptor subfamily 1, group I, member 3
NR3C2 nuclear receptor subfamily 3, group C, member 2
NRG1 neuregulin 1
OPRM1 opioid receptor, mu 1
OXT oxytocin/neurophysin I prepropeptide
OXTR oxytocin receptor
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PCDH15 protocadherin-related 15
PDE4D phosphodiesterase 4D, cAMP-specific
PENK proenkephalin
PNN pinin, desmosome associated protein
PRB1 proline-rich protein BstNI subfamily 1
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRL prolactin
PTCH1 patched 1
PTPN12 protein tyrosine phosphatase, non-receptor type 12
RET ret proto-oncogene
RPS29 ribosomal protein S29
RXRG retinoid X receptor, gamma
SCLY selenocysteine lyase
SELENBP1 selenium binding protein 1
SGK223 homolog of rat pragma of Rnd2
SHBG sex hormone-binding globulin
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SNAP25 synaptosomal-associated protein, 25kDa
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOSTDC1 sclerostin domain containing 1
SPDEF SAM pointed domain containing ETS transcription factor
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)
SRPX sushi-repeat containing protein, X-linked
TACC2 transforming, acidic coiled-coil containing protein 2
TAL1 T-cell acute lymphocytic leukemia 1
TAS2R38 taste receptor, type 2, member 38
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TMPRSS9 transmembrane protease, serine 9
TNF tumor necrosis factor
TPH2 tryptophan hydroxylase 2
TRIM13 tripartite motif containing 13
WSCD2 WSC domain containing 2
XBP1 X-box binding protein 1
XKR6 XK, Kell blood group complex subunit-related family, member 6