| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nevirapine perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Nevirapine_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FBN1 | fibrillin 1 | 0.0793158 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0487932 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0448539 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0444531 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0405794 |
| UBC | ubiquitin C | 0.0402215 |
| LOXL2 | lysyl oxidase-like 2 | 0.0388598 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0358044 |
| SBF2 | SET binding factor 2 | 0.0352419 |
| ATP13A3 | ATPase type 13A3 | 0.0344388 |
| OGA | O-GlcNAcase | 0.0301905 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0300928 |
| COL1A2 | collagen, type I, alpha 2 | 0.0285955 |
| OPTN | optineurin | 0.0271623 |
| SQSTM1 | sequestosome 1 | 0.0270992 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0269109 |
| GPC6 | glypican 6 | 0.025729 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0249308 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.024871 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0244386 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0239186 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0237972 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0237941 |
| CD109 | CD109 molecule | 0.0231527 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0227689 |
| AUTS2 | autism susceptibility candidate 2 | 0.0223919 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0217325 |
| GOLGA4 | golgin A4 | 0.0214583 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.021386 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0213624 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0211976 |
| NAV2 | neuron navigator 2 | 0.0210051 |
| PLEC | plectin | 0.0208357 |
| MEF2A | myocyte enhancer factor 2A | 0.0206344 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0201444 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0198544 |
| ARRDC3 | arrestin domain containing 3 | 0.0194049 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0191385 |
| STC1 | stanniocalcin 1 | 0.0190545 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0189092 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.018749 |
| RNF145 | ring finger protein 145 | 0.0186956 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | 0.0185883 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0185746 |
| HIP1 | huntingtin interacting protein 1 | 0.0184995 |
| HELZ | helicase with zinc finger | 0.01836 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0180858 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0180703 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0179871 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0177923 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0177728 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0176971 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0176787 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0174111 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0170416 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0169334 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0168176 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | 0.0166128 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0165284 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0165069 |
| SEPTIN9 | septin 9 | 0.0164827 |
| FMNL2 | formin-like 2 | 0.0162745 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0162657 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0162079 |
| USP12 | ubiquitin specific peptidase 12 | 0.0160591 |
| FLNB | filamin B, beta | 0.015967 |
| TMOD1 | tropomodulin 1 | 0.0158343 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0157648 |
| SDC4 | syndecan 4 | 0.0157261 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.015676 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0153426 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0152682 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0152547 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0152061 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0151681 |
| C1D | C1D nuclear receptor corepressor | 0.0149127 |
| DENND4C | DENN/MADD domain containing 4C | 0.0148343 |
| YEATS2 | YEATS domain containing 2 | 0.0146743 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0145653 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0144315 |
| XPO1 | exportin 1 | 0.0144196 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0142948 |
| FNBP1L | formin binding protein 1-like | 0.0142624 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0142392 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.0142062 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0141779 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | 0.0140827 |
| DENND4A | DENN/MADD domain containing 4A | 0.0140089 |
| APP | amyloid beta (A4) precursor protein | 0.0138837 |
| ZNF207 | zinc finger protein 207 | 0.0138535 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0137773 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0137769 |
| COL3A1 | collagen, type III, alpha 1 | 0.0136668 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0136391 |
| TFG | TRK-fused gene | 0.0135466 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0132204 |
| SPAG9 | sperm associated antigen 9 | 0.0131891 |
| RNF24 | ring finger protein 24 | 0.0130904 |
| ZNF148 | zinc finger protein 148 | 0.0130871 |
| HBP1 | HMG-box transcription factor 1 | 0.0130821 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.24423 |
| TMSB10 | thymosin beta 10 | -0.182215 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.16753 |
| CDH13 | cadherin 13 | -0.130632 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.121288 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.119785 |
| PODXL | podocalyxin-like | -0.110197 |
| MT2A | metallothionein 2A | -0.102342 |
| MAP1B | microtubule-associated protein 1B | -0.0980815 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0809568 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0796849 |
| FN1 | fibronectin 1 | -0.0729475 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0677115 |
| LOX | lysyl oxidase | -0.0673034 |
| COL5A1 | collagen, type V, alpha 1 | -0.0659964 |
| SUCNR1 | succinate receptor 1 | -0.0598589 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0592093 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0591603 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0526659 |
| CSTB | cystatin B (stefin B) | -0.0507129 |
| EGFR | epidermal growth factor receptor | -0.0479581 |
| B2M | beta-2-microglobulin | -0.0473389 |
| NAV1 | neuron navigator 1 | -0.045354 |
| LMNA | lamin A/C | -0.0452029 |
| PRSS23 | protease, serine, 23 | -0.0440144 |
| AHNAK | AHNAK nucleoprotein | -0.0437218 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0410593 |
| S100A10 | S100 calcium binding protein A10 | -0.0407245 |
| TPM4 | tropomyosin 4 | -0.0404658 |
| EFNA5 | ephrin-A5 | -0.0398625 |
| POTEF | POTE ankyrin domain family, member F | -0.0388696 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0384818 |
| PLAT | plasminogen activator, tissue | -0.0380946 |
| CALR | calreticulin | -0.0380068 |
| RIGI | RNA sensor RIG-I | -0.0369221 |
| HLA-B | major histocompatibility complex, class I, B | -0.0367809 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0367361 |
| MX2 | MX dynamin-like GTPase 2 | -0.0360932 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0359505 |
| PTMA | prothymosin, alpha | -0.0342577 |
| S100A6 | S100 calcium binding protein A6 | -0.0342485 |
| ASPH | aspartate beta-hydroxylase | -0.0342009 |
| CANX | calnexin | -0.0339932 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0322524 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0310986 |
| MEIS2 | Meis homeobox 2 | -0.0310965 |
| FSTL1 | follistatin-like 1 | -0.0308426 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0298497 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.02954 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0289023 |
| S100A11 | S100 calcium binding protein A11 | -0.0281 |
| LRRC17 | leucine rich repeat containing 17 | -0.0276684 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0274877 |
| FRMD4A | FERM domain containing 4A | -0.0273919 |
| SP100 | SP100 nuclear antigen | -0.0273873 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0273773 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0271439 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.0271234 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0270112 |
| CAVIN1 | caveolae associated protein 1 | -0.0268414 |
| CD44 | CD44 molecule (Indian blood group) | -0.0262113 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0258522 |
| TPM1 | tropomyosin 1 (alpha) | -0.0258035 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0254152 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0252849 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0248504 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.02476 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0247532 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0245303 |
| TAGLN2 | transgelin 2 | -0.0243438 |
| CYTH3 | cytohesin 3 | -0.0235757 |
| RPL35A | ribosomal protein L35a | -0.0232487 |
| FTL | ferritin, light polypeptide | -0.0230913 |
| SEC61G | Sec61 gamma subunit | -0.0230437 |
| PLXNA2 | plexin A2 | -0.0228202 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0227421 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0223117 |
| PKM | pyruvate kinase, muscle | -0.0222964 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0222003 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | -0.022179 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0219123 |
| PGK1 | phosphoglycerate kinase 1 | -0.0218723 |
| HLA-C | major histocompatibility complex, class I, C | -0.021833 |
| RPL37A | ribosomal protein L37a | -0.0215775 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.021524 |
| CUX1 | cut-like homeobox 1 | -0.0214918 |
| ANKRD11 | ankyrin repeat domain 11 | -0.021436 |
| RPL36 | ribosomal protein L36 | -0.0212561 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.0211384 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.020804 |
| CCND1 | cyclin D1 | -0.0207409 |
| PFN1 | profilin 1 | -0.0202341 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0201911 |
| RPS24 | ribosomal protein S24 | -0.0200163 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0200095 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0199329 |
| TMSB4X | thymosin beta 4, X-linked | -0.0198176 |
| CD59 | CD59 molecule, complement regulatory protein | -0.019702 |
| PCDH7 | protocadherin 7 | -0.019544 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0194554 |
