| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nevirapine perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Nevirapine_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0587034 |
| PLEC | plectin | 0.0569728 |
| ATP13A3 | ATPase type 13A3 | 0.0504215 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0491843 |
| SMAD3 | SMAD family member 3 | 0.0442605 |
| SPAG9 | sperm associated antigen 9 | 0.0348877 |
| ZNF292 | zinc finger protein 292 | 0.031073 |
| ARRDC3 | arrestin domain containing 3 | 0.0308392 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0291582 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0280906 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0277299 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.02739 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0256704 |
| USP3 | ubiquitin specific peptidase 3 | 0.0254807 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.025171 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0247054 |
| POSTN | periostin, osteoblast specific factor | 0.0236524 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0227085 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0225713 |
| FLNA | filamin A, alpha | 0.0208873 |
| TFG | TRK-fused gene | 0.020688 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0204763 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0201254 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0196476 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0195784 |
| PCBP2 | poly(rC) binding protein 2 | 0.0192817 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0191525 |
| CENPF | centromere protein F, 350/400kDa | 0.0190969 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0182733 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0182335 |
| RPL3 | ribosomal protein L3 | 0.0175753 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.017279 |
| RLF | rearranged L-myc fusion | 0.0171858 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0166964 |
| ECT2 | epithelial cell transforming 2 | 0.0166276 |
| RASA2 | RAS p21 protein activator 2 | 0.0164807 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0164246 |
| PDE8A | phosphodiesterase 8A | 0.0162354 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0160691 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0160071 |
| PTK2 | protein tyrosine kinase 2 | 0.015997 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0159407 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0158929 |
| RNF145 | ring finger protein 145 | 0.0154949 |
| ZNF148 | zinc finger protein 148 | 0.015441 |
| KIF1B | kinesin family member 1B | 0.0149588 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0149484 |
| SRPK2 | SRSF protein kinase 2 | 0.0146174 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0141699 |
| MLF1 | myeloid leukemia factor 1 | 0.014167 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0141326 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0137691 |
| RBM39 | RNA binding motif protein 39 | 0.0137424 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0136899 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0135746 |
| TMEM39A | transmembrane protein 39A | 0.0133553 |
| FNBP1L | formin binding protein 1-like | 0.0133336 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0133 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0132862 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.0132014 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0131898 |
| AFAP1 | actin filament associated protein 1 | 0.0130893 |
| ANLN | anillin, actin binding protein | 0.0130849 |
| RYBP | RING1 and YY1 binding protein | 0.0130323 |
| ECE1 | endothelin converting enzyme 1 | 0.0130288 |
| TXNRD1 | thioredoxin reductase 1 | 0.0127869 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0127856 |
| MSN | moesin | 0.0127682 |
| ANXA5 | annexin A5 | 0.012693 |
| CCNL1 | cyclin L1 | 0.0126575 |
| MKI67 | marker of proliferation Ki-67 | 0.012298 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0122003 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0121153 |
| FOSL1 | FOS-like antigen 1 | 0.0120621 |
| QKI | QKI, KH domain containing, RNA binding | 0.0117553 |
| AZIN1 | antizyme inhibitor 1 | 0.0117103 |
| PHIP | pleckstrin homology domain interacting protein | 0.0115512 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0114744 |
| SLMAP | sarcolemma associated protein | 0.0114521 |
| MAP1B | microtubule-associated protein 1B | 0.0114117 |
| NUP58 | nucleoporin 58 | 0.0113968 |
| XPO1 | exportin 1 | 0.0112865 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0112578 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0109511 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0109421 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0109205 |
| SUCO | SUN domain containing ossification factor | 0.0109119 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0106132 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0105949 |
| DIAPH3 | diaphanous-related formin 3 | 0.0105693 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.010546 |
| HELZ | helicase with zinc finger | 0.0104983 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0104975 |
| RRM2 | ribonucleotide reductase M2 | 0.0104709 |
| FOXJ3 | forkhead box J3 | 0.0104478 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0104056 |
| MTF2 | metal response element binding transcription factor 2 | 0.0102305 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0101995 |
| DDB1 | damage-specific DNA binding protein 1, 127kDa | 0.0101763 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0101755 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.289171 |
| VIM | vimentin | -0.183979 |
| CDH13 | cadherin 13 | -0.144622 |
| TMSB10 | thymosin beta 10 | -0.139521 |
| NDRG1 | N-myc downstream regulated 1 | -0.0994923 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0958293 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0951167 |
| MT2A | metallothionein 2A | -0.0938582 |
| COL1A1 | collagen, type I, alpha 1 | -0.0930093 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0899322 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0868795 |
| FBN1 | fibrillin 1 | -0.0805228 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0777278 |
| IER3 | immediate early response 3 | -0.0760105 |
| FTL | ferritin, light polypeptide | -0.075246 |
| COL1A2 | collagen, type I, alpha 2 | -0.0729562 |
| RPL35A | ribosomal protein L35a | -0.0705914 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0686959 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0621221 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0618706 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0592984 |
| RPS8 | ribosomal protein S8 | -0.0576364 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0565026 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0563309 |
| ENO1 | enolase 1, (alpha) | -0.0548847 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0521947 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0500589 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0498281 |
| ASPH | aspartate beta-hydroxylase | -0.0481335 |
| RPS3 | ribosomal protein S3 | -0.0463677 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.04624 |
| COL5A1 | collagen, type V, alpha 1 | -0.0460442 |
| ACTG1 | actin gamma 1 | -0.0459915 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0456046 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0452879 |
| RPL37A | ribosomal protein L37a | -0.0440936 |
| GLIS3 | GLIS family zinc finger 3 | -0.043739 |
| CALR | calreticulin | -0.0424039 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0409924 |
| LOX | lysyl oxidase | -0.0404783 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0396769 |
| CALD1 | caldesmon 1 | -0.0392231 |
| HLA-B | major histocompatibility complex, class I, B | -0.0391968 |
| RPS6 | ribosomal protein S6 | -0.03889 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0381803 |
| VCAN | versican | -0.0380734 |
| GOLGB1 | golgin B1 | -0.0373132 |
| IL6 | interleukin 6 | -0.0360207 |
| RPLP2 | ribosomal protein, large, P2 | -0.0359388 |
| RPS19 | ribosomal protein S19 | -0.0358443 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0351252 |
| S100A9 | S100 calcium binding protein A9 | -0.034555 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0341582 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0338202 |
| PTMA | prothymosin, alpha | -0.0337854 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0331509 |
| MTDH | metadherin | -0.0330425 |
| RPL26 | ribosomal protein L26 | -0.0326844 |
| RPL23 | ribosomal protein L23 | -0.0323389 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0312112 |
| EGFR | epidermal growth factor receptor | -0.0312107 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0311474 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0308144 |
| RPL30 | ribosomal protein L30 | -0.0306346 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0303492 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0302053 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0301776 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0301053 |
| RPS12 | ribosomal protein S12 | -0.0300112 |
| CANX | calnexin | -0.0299851 |
| ATXN1 | ataxin 1 | -0.0299123 |
| RPL28 | ribosomal protein L28 | -0.0299069 |
| RPS25 | ribosomal protein S25 | -0.0298213 |
| RPL19 | ribosomal protein L19 | -0.0297626 |
| RACK1 | receptor for activated C kinase 1 | -0.0295002 |
| RND3 | Rho family GTPase 3 | -0.0293669 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0293332 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0292047 |
| RPL11 | ribosomal protein L11 | -0.028862 |
| VCL | vinculin | -0.028795 |
| RPL5 | ribosomal protein L5 | -0.0286371 |
| RPL36 | ribosomal protein L36 | -0.0284694 |
| CAVIN1 | caveolae associated protein 1 | -0.0282836 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0281017 |
| CD44 | CD44 molecule (Indian blood group) | -0.0280743 |
| S100A6 | S100 calcium binding protein A6 | -0.0279724 |
| RPL31 | ribosomal protein L31 | -0.0279116 |
| CNTN5 | contactin 5 | -0.0273648 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0273257 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0272076 |
| RPL9 | ribosomal protein L9 | -0.0270575 |
| NAV1 | neuron navigator 1 | -0.0269414 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0266966 |
| OSMR | oncostatin M receptor | -0.0265069 |
| RPL7 | ribosomal protein L7 | -0.0263579 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0256768 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0256186 |
| RPS27A | ribosomal protein S27a | -0.025545 |
| RPS13 | ribosomal protein S13 | -0.0255214 |
| RPL12 | ribosomal protein L12 | -0.0254248 |
