| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nevirapine perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Nevirapine_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.154985 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0757531 |
| RNF145 | ring finger protein 145 | 0.072575 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0687663 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0686576 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0682956 |
| RBM39 | RNA binding motif protein 39 | 0.0656938 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0654629 |
| EREG | epiregulin | 0.065162 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0647365 |
| MED13L | mediator complex subunit 13-like | 0.063501 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0593625 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0563393 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0553232 |
| FAM13A | family with sequence similarity 13, member A | 0.0526014 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.050959 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0505114 |
| GOLGA4 | golgin A4 | 0.0504359 |
| TFG | TRK-fused gene | 0.0493587 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0491605 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0489538 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0477135 |
| USP3 | ubiquitin specific peptidase 3 | 0.0453057 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0447698 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0447131 |
| NUP58 | nucleoporin 58 | 0.0428404 |
| PUM1 | pumilio RNA-binding family member 1 | 0.041251 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0407859 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0406341 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0401805 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0399221 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0390708 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.039051 |
| ZNF292 | zinc finger protein 292 | 0.0387313 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0386945 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0377616 |
| TXNIP | thioredoxin interacting protein | 0.0376477 |
| RPL3 | ribosomal protein L3 | 0.0373793 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0370803 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0368544 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0367918 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0356439 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0354431 |
| WDR43 | WD repeat domain 43 | 0.0353745 |
| NDRG1 | N-myc downstream regulated 1 | 0.0352666 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0350078 |
| HELZ | helicase with zinc finger | 0.0347065 |
| FNBP1L | formin binding protein 1-like | 0.0345917 |
| VEGFA | vascular endothelial growth factor A | 0.0339062 |
| COG5 | component of oligomeric golgi complex 5 | 0.0331286 |
| RLF | rearranged L-myc fusion | 0.0328037 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0326763 |
| CCNY | cyclin Y | 0.0324509 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0323398 |
| WDR45B | WD repeat domain 45B | 0.0321383 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0318327 |
| SETD5 | SET domain containing 5 | 0.0315288 |
| NCKAP1 | NCK-associated protein 1 | 0.0314989 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0314497 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0313183 |
| CCNL1 | cyclin L1 | 0.0313033 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0309518 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0309436 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0305755 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0304018 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0304008 |
| MATR3 | matrin 3 | 0.0303884 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0303635 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0303376 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0303114 |
| COPA | coatomer protein complex, subunit alpha | 0.0300787 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0295332 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0294861 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.029362 |
| PCBP2 | poly(rC) binding protein 2 | 0.0292647 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0287495 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.028705 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0283711 |
| ANXA11 | annexin A11 | 0.0281692 |
| XPO1 | exportin 1 | 0.0281408 |
| PLEC | plectin | 0.0279937 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0277003 |
| PRRC1 | proline-rich coiled-coil 1 | 0.0272431 |
| NEK7 | NIMA-related kinase 7 | 0.0271977 |
| YME1L1 | YME1-like 1 ATPase | 0.0270606 |
| RREB1 | ras responsive element binding protein 1 | 0.02701 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0269957 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0268611 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0267356 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0265952 |
| TPM3 | tropomyosin 3 | 0.0265819 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0265089 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0264568 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0264526 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0262659 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0262209 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0260359 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0259047 |
| H2AC6 | H2A clustered histone 6 | 0.0257962 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0257956 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.124667 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.118047 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.110708 |
| MYO1E | myosin IE | -0.0826939 |
| ANTXR2 | anthrax toxin receptor 2 | -0.059749 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0530691 |
| TMSB10 | thymosin beta 10 | -0.0496567 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0452577 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0431351 |
| VCL | vinculin | -0.0423989 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.036736 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0353802 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0346887 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0345303 |
| FHIT | fragile histidine triad | -0.0342107 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.033677 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0324025 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.031666 |
| RAD51B | RAD51 paralog B | -0.0313935 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.031312 |
| ACTG1 | actin gamma 1 | -0.0310267 |
| LAMA4 | laminin, alpha 4 | -0.030578 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0305647 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0304621 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0295027 |
| ONECUT3 | one cut homeobox 3 | -0.0288531 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0285392 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0275701 |
| EGFR | epidermal growth factor receptor | -0.027437 |
| POF1B | premature ovarian failure, 1B | -0.0272665 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0262662 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0261754 |
| RNF217 | ring finger protein 217 | -0.0260514 |
| PALLD | palladin, cytoskeletal associated protein | -0.0258156 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0249365 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0248375 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0241806 |
| SMYD3 | SET and MYND domain containing 3 | -0.0237071 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0224071 |
| PCDH9 | protocadherin 9 | -0.0214649 |
| FLNB | filamin B, beta | -0.0211445 |
| MT2A | metallothionein 2A | -0.020749 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0205065 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.020097 |
| RIN2 | Ras and Rab interactor 2 | -0.0199899 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0197853 |
| MECOM | MDS1 and EVI1 complex locus | -0.0195549 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0194144 |
| ATXN1 | ataxin 1 | -0.0191098 |
| PRELID2 | PRELI domain containing 2 | -0.0180903 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0180858 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0180677 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0179667 |
| ASPH | aspartate beta-hydroxylase | -0.0179218 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0178214 |
| KLF6 | Kruppel-like factor 6 | -0.017809 |
| SH3D19 | SH3 domain containing 19 | -0.0177008 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0175656 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0175413 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0174547 |
| MUC13 | mucin 13, cell surface associated | -0.0174387 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0174 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0167147 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0166659 |
| IER3 | immediate early response 3 | -0.0160143 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0159758 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0159084 |
| AHNAK | AHNAK nucleoprotein | -0.0157907 |
| EXOC4 | exocyst complex component 4 | -0.0155973 |
| RPL26 | ribosomal protein L26 | -0.0155809 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0155688 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0154855 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0154404 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.0149559 |
| EFNB2 | ephrin-B2 | -0.014933 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0147591 |
| AHCYL2 | adenosylhomocysteinase-like 2 | -0.0146974 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0145389 |
| MUC17 | mucin 17, cell surface associated | -0.0143571 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0143351 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0143172 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0142666 |
| RPS8 | ribosomal protein S8 | -0.0141886 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | -0.0138985 |
| SVIL | supervillin | -0.0138673 |
| CCDC146 | coiled-coil domain containing 146 | -0.0138376 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0137849 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0137834 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | -0.0137573 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0137237 |
| DIAPH2 | diaphanous-related formin 2 | -0.0136358 |
| DENND1A | DENN/MADD domain containing 1A | -0.0136332 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0135489 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0134647 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0133984 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0133861 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0133661 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0132401 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.013182 |
| FRMD5 | FERM domain containing 5 | -0.0129111 |
