| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nevirapine perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Nevirapine_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.157007 |
| EFNA5 | ephrin-A5 | 0.13899 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.111505 |
| FN1 | fibronectin 1 | 0.104729 |
| GPC6 | glypican 6 | 0.101514 |
| VGF | VGF nerve growth factor inducible | 0.0908582 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0897896 |
| JMJD1C | jumonji domain containing 1C | 0.0888925 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.085738 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0851241 |
| NDRG1 | N-myc downstream regulated 1 | 0.083664 |
| DST | dystonin | 0.0823626 |
| PDE10A | phosphodiesterase 10A | 0.0781625 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0781469 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0777825 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0777202 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0668544 |
| SPAG9 | sperm associated antigen 9 | 0.065233 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.064275 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0634929 |
| ASPH | aspartate beta-hydroxylase | 0.063215 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0627241 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0604213 |
| STC1 | stanniocalcin 1 | 0.0596774 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0596059 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0595311 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0583105 |
| USP34 | ubiquitin specific peptidase 34 | 0.0582048 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0555005 |
| APP | amyloid beta (A4) precursor protein | 0.0549954 |
| HELZ | helicase with zinc finger | 0.0548404 |
| CALU | calumenin | 0.0523338 |
| RORA | RAR-related orphan receptor A | 0.0518263 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0517589 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0513178 |
| CANX | calnexin | 0.0512967 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0507379 |
| SMYD3 | SET and MYND domain containing 3 | 0.0505989 |
| FLNB | filamin B, beta | 0.0492466 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0489401 |
| RTN4 | reticulon 4 | 0.0487066 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0486355 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0480913 |
| TMEM165 | transmembrane protein 165 | 0.0478032 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0470421 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0459053 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0447715 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0446122 |
| CD44 | CD44 molecule (Indian blood group) | 0.0442632 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0442591 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0438447 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0418378 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0400818 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0382644 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0378873 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0377418 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0355287 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0354487 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0350192 |
| SCFD1 | sec1 family domain containing 1 | 0.0344534 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0337089 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0336488 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0334784 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0328704 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0327126 |
| LAMB3 | laminin, beta 3 | 0.0320993 |
| PRKCA | protein kinase C, alpha | 0.0320255 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0317167 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0314578 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0314289 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0299775 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0299588 |
| MAP4 | microtubule-associated protein 4 | 0.0281442 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0278916 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0269329 |
| METTL15 | methyltransferase like 15 | 0.0266948 |
| MYO1E | myosin IE | 0.02549 |
| TXNRD1 | thioredoxin reductase 1 | 0.0248066 |
| RUNX1 | runt-related transcription factor 1 | 0.0248022 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0234074 |
| OGA | O-GlcNAcase | 0.0226125 |
| RBM39 | RNA binding motif protein 39 | 0.0225315 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0218554 |
| RNF145 | ring finger protein 145 | 0.0208289 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0204659 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0201946 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.020194 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0197615 |
| MATR3 | matrin 3 | 0.0193477 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0191417 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.018716 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0168973 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0165084 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.0147218 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0134577 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0128753 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0112885 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0108908 |
| GNAS | GNAS complex locus | 0.0106338 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0100676 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.145741 |
| LMO7 | LIM domain 7 | -0.133173 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.109329 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.106659 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0995601 |
| VIM | vimentin | -0.0979103 |
| RPS6 | ribosomal protein S6 | -0.097359 |
| PGK1 | phosphoglycerate kinase 1 | -0.0800702 |
| B2M | beta-2-microglobulin | -0.079779 |
| LDHA | lactate dehydrogenase A | -0.0790675 |
| NAV2 | neuron navigator 2 | -0.0785251 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0773909 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0757703 |
| RPL35A | ribosomal protein L35a | -0.0746036 |
| RPS12 | ribosomal protein S12 | -0.0704487 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0696539 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0689659 |
| IGF2 | insulin-like growth factor 2 | -0.0632889 |
| EGFR | epidermal growth factor receptor | -0.0629845 |
| HLA-B | major histocompatibility complex, class I, B | -0.0627533 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0626824 |
| RPL37A | ribosomal protein L37a | -0.0613907 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0571054 |
| FTL | ferritin, light polypeptide | -0.0564219 |
| RPL7A | ribosomal protein L7a | -0.0556103 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0550007 |
| RPS8 | ribosomal protein S8 | -0.0547945 |
| MT2A | metallothionein 2A | -0.0545346 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0538822 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.05364 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0536285 |
| RPL19 | ribosomal protein L19 | -0.0515817 |
| RPS13 | ribosomal protein S13 | -0.0505399 |
| MSI2 | musashi RNA-binding protein 2 | -0.0493366 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0489478 |
| ACTG1 | actin gamma 1 | -0.0489319 |
| RPLP1 | ribosomal protein, large, P1 | -0.048567 |
| ZNF292 | zinc finger protein 292 | -0.0480794 |
| BPTF | bromodomain PHD finger transcription factor | -0.0476562 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0475773 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0474339 |
| RPL26 | ribosomal protein L26 | -0.0472795 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0471922 |
| PDE8A | phosphodiesterase 8A | -0.0456059 |
| WASF2 | WAS protein family, member 2 | -0.044925 |
| AK1 | adenylate kinase 1 | -0.0447671 |
| DSPP | dentin sialophosphoprotein | -0.0430784 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0427948 |
| RPL11 | ribosomal protein L11 | -0.0416928 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0406641 |
| CALR | calreticulin | -0.0402167 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0394959 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0391526 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0389022 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0370547 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0366618 |
| CDK6 | cyclin-dependent kinase 6 | -0.0364408 |
| HM13 | histocompatibility (minor) 13 | -0.0353071 |
| RPL23 | ribosomal protein L23 | -0.0349931 |
| MED13L | mediator complex subunit 13-like | -0.034977 |
| CD2AP | CD2-associated protein | -0.0344574 |
| GOLGB1 | golgin B1 | -0.0343322 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0336415 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0329414 |
| RPL8 | ribosomal protein L8 | -0.0313956 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0310021 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0304271 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0303118 |
| ANXA2 | annexin A2 | -0.0302787 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0301584 |
| INSIG1 | insulin induced gene 1 | -0.0297888 |
| FAT1 | FAT atypical cadherin 1 | -0.0292931 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.029269 |
| USP33 | ubiquitin specific peptidase 33 | -0.0289375 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0288613 |
| RND3 | Rho family GTPase 3 | -0.0286752 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0286727 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0265753 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0259771 |
| ATOSA | atos homolog A | -0.0256347 |
| RPS21 | ribosomal protein S21 | -0.0245277 |
| MMP1 | matrix metallopeptidase 1 | -0.0242624 |
| WAPL | WAPL cohesin release factor | -0.0226334 |
| RPS3 | ribosomal protein S3 | -0.0218384 |
| TMSB10 | thymosin beta 10 | -0.0214036 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0213353 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0199662 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0190532 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0188032 |
| RPS19 | ribosomal protein S19 | -0.0188022 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0186024 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0179628 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0176671 |
| RBM25 | RNA binding motif protein 25 | -0.017075 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0158261 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0150848 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | -0.0148641 |
| PTK2 | protein tyrosine kinase 2 | -0.0140971 |
| EPN2 | epsin 2 | -0.0135005 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0134571 |
