| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nevirapine perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Nevirapine_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0428958 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0403536 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0390287 |
| CADM2 | cell adhesion molecule 2 | 0.0270158 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.025228 |
| RAD51B | RAD51 paralog B | 0.02042 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0203606 |
| PRKD1 | protein kinase D1 | 0.0191768 |
| NTM | neurotrimin | 0.0189241 |
| ARHGAP15 | Rho GTPase activating protein 15 | 0.0184084 |
| PARD3B | par-3 family cell polarity regulator beta | 0.017933 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0175827 |
| SKIL | SKI-like proto-oncogene | 0.0167044 |
| NBEAL1 | neurobeachin-like 1 | 0.0166864 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0162391 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0161788 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0159204 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0157084 |
| ZNF638 | zinc finger protein 638 | 0.0155617 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0154587 |
| ZFPM2 | zinc finger protein, FOG family member 2 | 0.014877 |
| MEIS2 | Meis homeobox 2 | 0.0148533 |
| MPG | N-methylpurine-DNA glycosylase | 0.0148194 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0146268 |
| LYST | lysosomal trafficking regulator | 0.0142636 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0141805 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0138205 |
| ABR | active BCR-related | 0.0136413 |
| NUMB | numb homolog (Drosophila) | 0.0135475 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0134846 |
| TENM2 | teneurin transmembrane protein 2 | 0.0134294 |
| NRXN1 | neurexin 1 | 0.0134271 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 0.0133082 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0132619 |
| KLHDC10 | kelch domain containing 10 | 0.0130311 |
| EZR | ezrin | 0.0130037 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0127524 |
| INSR | insulin receptor | 0.0127371 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0123823 |
| EXOC1 | exocyst complex component 1 | 0.0123414 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0123394 |
| KIF13A | kinesin family member 13A | 0.0122644 |
| ELP4 | elongator acetyltransferase complex subunit 4 | 0.012024 |
| C2CD5 | C2 calcium-dependent domain containing 5 | 0.0118768 |
| NFIA | nuclear factor I/A | 0.0118553 |
| SHROOM3 | shroom family member 3 | 0.0117551 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0116764 |
| ZHX3 | zinc fingers and homeoboxes 3 | 0.0115246 |
| CCDC200 | coiled-coil domain containing 200 | 0.0114879 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0114792 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0114601 |
| DYNC1I2 | dynein, cytoplasmic 1, intermediate chain 2 | 0.0114526 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0111338 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.011099 |
| PAX6 | paired box 6 | 0.0110325 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0110321 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0108611 |
| RNF149 | ring finger protein 149 | 0.0107954 |
| SLC6A4 | solute carrier family 6 (neurotransmitter transporter), member 4 | 0.0107284 |
| ATP6V0C | ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c | 0.0106819 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0106507 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0105817 |
| FST | follistatin | 0.0105756 |
| H2AC6 | H2A clustered histone 6 | 0.0105635 |
| TOX | thymocyte selection-associated high mobility group box | 0.0105298 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.010493 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0104512 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0103778 |
| MYO9A | myosin IXA | 0.0103739 |
| ATP9B | ATPase, class II, type 9B | 0.0103636 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0103379 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 0.0102779 |
| DUSP6 | dual specificity phosphatase 6 | 0.010268 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0102415 |
| ZFP30 | ZFP30 zinc finger protein | 0.0100922 |
| DOK6 | docking protein 6 | 0.0100814 |
| RIGI | RNA sensor RIG-I | 0.010073 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | 0.0100548 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0100413 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0100342 |
| SP4 | Sp4 transcription factor | 0.0100143 |
| TGM2 | transglutaminase 2 | 0.00997716 |
| TOM1L2 | target of myb1-like 2 (chicken) | 0.00989371 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00988599 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 0.00982661 |
| PSEN1 | presenilin 1 | 0.00979473 |
| CEP290 | centrosomal protein 290kDa | 0.00973157 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.00972451 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0097151 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.00968263 |
| ZBTB37 | zinc finger and BTB domain containing 37 | 0.00965356 |
| PDE8A | phosphodiesterase 8A | 0.00964505 |
| MBTPS1 | membrane-bound transcription factor peptidase, site 1 | 0.00958681 |
| VCL | vinculin | 0.00958417 |
| LCLAT1 | lysocardiolipin acyltransferase 1 | 0.00957464 |
| LPIN2 | lipin 2 | 0.00955713 |
| USP28 | ubiquitin specific peptidase 28 | 0.009549 |
| ZRANB3 | zinc finger, RAN-binding domain containing 3 | 0.00952026 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | 0.00951512 |
| CDH13 | cadherin 13 | 0.00948676 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.171484 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.153608 |
| PTMA | prothymosin, alpha | -0.139834 |
| TMSB10 | thymosin beta 10 | -0.13669 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.107297 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0901039 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0900544 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0849049 |
| THBS1 | thrombospondin 1 | -0.0833269 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0823732 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0739311 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0726792 |
| UBC | ubiquitin C | -0.0722613 |
| ITGAV | integrin, alpha V | -0.0669274 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0649224 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0632584 |
| ACTG1 | actin gamma 1 | -0.0610574 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0607528 |
| POTEF | POTE ankyrin domain family, member F | -0.060238 |
| RPS27A | ribosomal protein S27a | -0.0598071 |
| APP | amyloid beta (A4) precursor protein | -0.0583442 |
| COL3A1 | collagen, type III, alpha 1 | -0.0568103 |
| TMSB4X | thymosin beta 4, X-linked | -0.0541478 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0539989 |
| SET | SET nuclear proto-oncogene | -0.0538254 |
| EMP1 | epithelial membrane protein 1 | -0.0502319 |
| ZNF292 | zinc finger protein 292 | -0.0499838 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0486092 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0475335 |
| RPS16 | ribosomal protein S16 | -0.0473254 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0459259 |
| PEG10 | paternally expressed 10 | -0.0457433 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0455485 |
| RPL5 | ribosomal protein L5 | -0.0449102 |
| CALR | calreticulin | -0.0438208 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0425251 |
| AHNAK | AHNAK nucleoprotein | -0.0420806 |
| PRRC2C | proline-rich coiled-coil 2C | -0.04144 |
| PCBP2 | poly(rC) binding protein 2 | -0.041196 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0396001 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0392313 |
| GPC3 | glypican 3 | -0.0391666 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0389936 |
| TPX2 | TPX2, microtubule-associated | -0.0384483 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0382945 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | -0.0380276 |
| RBM39 | RNA binding motif protein 39 | -0.0380055 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0379921 |
| CALU | calumenin | -0.0375455 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0367616 |
| RTN4 | reticulon 4 | -0.0367055 |
| HMGB2 | high mobility group box 2 | -0.0366445 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0365622 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0364576 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0359683 |
| S100A10 | S100 calcium binding protein A10 | -0.035951 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0355437 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0355005 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0354063 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0346452 |
| SRP54 | signal recognition particle 54kDa | -0.03452 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0342861 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0341913 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0340831 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0339032 |
| ENO1 | enolase 1, (alpha) | -0.0335362 |
| SPAG9 | sperm associated antigen 9 | -0.0328283 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0327931 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0320205 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0319969 |
| HDAC9 | histone deacetylase 9 | -0.0319867 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0318622 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0312415 |
| RPS8 | ribosomal protein S8 | -0.0309363 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.0309212 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0301534 |
| SMYD3 | SET and MYND domain containing 3 | -0.0301529 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0297909 |
| MKI67 | marker of proliferation Ki-67 | -0.0295896 |
| WDR43 | WD repeat domain 43 | -0.0295311 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0293231 |
| SRP72 | signal recognition particle 72kDa | -0.0292048 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0290463 |
| ANXA2 | annexin A2 | -0.0287686 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0285264 |
| CANX | calnexin | -0.0282796 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0282737 |
| TXNRD1 | thioredoxin reductase 1 | -0.0282041 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.028101 |
| RPL23 | ribosomal protein L23 | -0.0280275 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0278967 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | -0.0275409 |
| CDK6 | cyclin-dependent kinase 6 | -0.0275179 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0273925 |
| NCKAP1 | NCK-associated protein 1 | -0.0273233 |
| SEPTIN7 | septin 7 | -0.0272119 |
| YBX1 | Y box binding protein 1 | -0.0271967 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0270542 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0270408 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | -0.0270396 |
