Nevirapine_SNU-1 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Nevirapine perturbation in SNU-1 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Nevirapine_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0902223
VCL vinculin 0.0835802
RBM39 RNA binding motif protein 39 0.0800104
RPL3 ribosomal protein L3 0.0794841
PDE4D phosphodiesterase 4D, cAMP-specific 0.077953
TXNRD1 thioredoxin reductase 1 0.0771564
EEF2 eukaryotic translation elongation factor 2 0.0767547
TJP1 tight junction protein 1 0.0761528
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0760103
EML4 echinoderm microtubule associated protein like 4 0.0748111
ADAM10 ADAM metallopeptidase domain 10 0.0747156
WAC WW domain containing adaptor with coiled-coil 0.0653029
ZFAND3 zinc finger, AN1-type domain 3 0.0639429
ANKRD11 ankyrin repeat domain 11 0.0624946
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0615601
STAT1 signal transducer and activator of transcription 1, 91kDa 0.0599624
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.0576565
NAMPT nicotinamide phosphoribosyltransferase 0.0555722
PKM pyruvate kinase, muscle 0.054195
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0537609
ADAM9 ADAM metallopeptidase domain 9 0.0533593
PDGFC platelet derived growth factor C 0.0527614
RTN4 reticulon 4 0.0523353
TFG TRK-fused gene 0.0522471
KDM3A lysine (K)-specific demethylase 3A 0.0514111
NCKAP1 NCK-associated protein 1 0.0499109
PCBP2 poly(rC) binding protein 2 0.0498948
GOLGA4 golgin A4 0.0498695
GSK3B glycogen synthase kinase 3 beta 0.0494154
DSCAM Down syndrome cell adhesion molecule 0.0477483
SSBP2 single-stranded DNA binding protein 2 0.047589
PYGB phosphorylase, glycogen; brain 0.0472888
PRRC2C proline-rich coiled-coil 2C 0.0471561
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.0465557
NUP58 nucleoporin 58 0.0461311
ZNF292 zinc finger protein 292 0.0460983
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0456853
KMT2E lysine (K)-specific methyltransferase 2E 0.0446713
CRY1 cryptochrome circadian clock 1 0.0444222
KDM6A lysine (K)-specific demethylase 6A 0.0441684
UBE2D3 ubiquitin-conjugating enzyme E2D 3 0.0436096
CCNL1 cyclin L1 0.0433986
EIF4A2 eukaryotic translation initiation factor 4A2 0.042334
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0422252
PTBP2 polypyrimidine tract binding protein 2 0.0421671
LOC112694756 uncharaterized LOC112694756 0.0415014
MSI2 musashi RNA-binding protein 2 0.0412372
GNPDA1 glucosamine-6-phosphate deaminase 1 0.0397267
CDC73 cell division cycle 73 0.03959
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 0.0390649
ECT2 epithelial cell transforming 2 0.0390293
WDR43 WD repeat domain 43 0.0390038
PTK2 protein tyrosine kinase 2 0.0389383
AHNAK AHNAK nucleoprotein 0.0383173
LUC7L2 LUC7-like 2 (S. cerevisiae) 0.0380182
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0379294
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0373948
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 0.0370673
EXOC6B exocyst complex component 6B 0.0365606
MAP3K2 mitogen-activated protein kinase kinase kinase 2 0.0364161
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.0359998
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0357539
EGFR epidermal growth factor receptor 0.0356009
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) 0.0354391
QKI QKI, KH domain containing, RNA binding 0.0352062
COG5 component of oligomeric golgi complex 5 0.0350994
FNDC3B fibronectin type III domain containing 3B 0.0348994
YAP1 Yes-associated protein 1 0.0346705
HDLBP high density lipoprotein binding protein 0.0346152
STRN3 striatin, calmodulin binding protein 3 0.0343006
CSDE1 cold shock domain containing E1, RNA-binding 0.0342151
PUM2 pumilio RNA-binding family member 2 0.0340698
PARD3 par-3 family cell polarity regulator 0.0336384
UBC ubiquitin C 0.0336064
PGK1 phosphoglycerate kinase 1 0.0333278
SPRED2 sprouty-related, EVH1 domain containing 2 0.0332748
NBAS neuroblastoma amplified sequence 0.0330719
EZR ezrin 0.0330102
FAM91A1 family with sequence similarity 91, member A1 0.0329951
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0329529
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.0328545
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 0.0328123
PIWIL1 piwi-like RNA-mediated gene silencing 1 0.03266
HDAC9 histone deacetylase 9 0.0326118
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 0.032442
MATR3 matrin 3 0.0324174
ZNF644 zinc finger protein 644 0.0318699
FLNB filamin B, beta 0.031793
ANKRD17 ankyrin repeat domain 17 0.0317729
KMT2C lysine (K)-specific methyltransferase 2C 0.0317352
SRRM2 serine/arginine repetitive matrix 2 0.0312094
PHC3 polyhomeotic homolog 3 (Drosophila) 0.0309402
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 0.0309185
RHEB Ras homolog enriched in brain 0.0304355
FXR1 fragile X mental retardation, autosomal homolog 1 0.0304215
CALU calumenin 0.0303039
RHOA ras homolog family member A 0.0302834
APP amyloid beta (A4) precursor protein 0.0300844
BIRC6 baculoviral IAP repeat containing 6 0.0298992
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0298653

decreased expression

Symbol Name Standardized Value
PTMA prothymosin, alpha -0.148334
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 -0.0747935
RPS8 ribosomal protein S8 -0.0618944
TPT1 tumor protein, translationally-controlled 1 -0.0590202
PFN1 profilin 1 -0.0511258
RPL35A ribosomal protein L35a -0.0507668
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0499978
RPS6 ribosomal protein S6 -0.0479448
RPLP2 ribosomal protein, large, P2 -0.0463962
BMP10 bone morphogenetic protein 10 -0.0454617
RPL7A ribosomal protein L7a -0.0444635
CPED1 cadherin-like and PC-esterase domain containing 1 -0.0437111
RPLP1 ribosomal protein, large, P1 -0.0424889
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0383581
RPL37A ribosomal protein L37a -0.0379741
RPL31 ribosomal protein L31 -0.0379371
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.0341696
RPL26 ribosomal protein L26 -0.03402
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0330594
RPL36 ribosomal protein L36 -0.0325376
RPS13 ribosomal protein S13 -0.0323924
RPL34 ribosomal protein L34 -0.0319726
DLG1 discs, large homolog 1 (Drosophila) -0.0314458
RPL9 ribosomal protein L9 -0.0312186
SMC4 structural maintenance of chromosomes 4 -0.0310772
TMSB10 thymosin beta 10 -0.0303379
RPS19 ribosomal protein S19 -0.0296495
RACK1 receptor for activated C kinase 1 -0.0291081
FTL ferritin, light polypeptide -0.0285201
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.0282125
HSPB1 heat shock 27kDa protein 1 -0.0273367
RPS21 ribosomal protein S21 -0.0265296
SDK1 sidekick cell adhesion molecule 1 -0.0264502
ACTG1 actin gamma 1 -0.0263954
DIAPH3 diaphanous-related formin 3 -0.0262904
RPS3 ribosomal protein S3 -0.0252323
RPS27A ribosomal protein S27a -0.0248653
RPS12 ribosomal protein S12 -0.0247984
S100A9 S100 calcium binding protein A9 -0.0243863
RFC3 replication factor C (activator 1) 3, 38kDa -0.02386
TM4SF1 transmembrane 4 L six family member 1 -0.0234669
RPS27 ribosomal protein S27 -0.0232882
HJURP Holliday junction recognition protein -0.023258
RPL18 ribosomal protein L18 -0.0229127
NAV2 neuron navigator 2 -0.0226138
RPL23 ribosomal protein L23 -0.0225052
RPL28 ribosomal protein L28 -0.0223211
RPS17 ribosomal protein S17 -0.0217766
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0216299
RPS16 ribosomal protein S16 -0.0210867
RPL12 ribosomal protein L12 -0.0209977
RPS29 ribosomal protein S29 -0.0209491
MKI67 marker of proliferation Ki-67 -0.0208812
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0208546
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -0.0204726
HMGA1 high mobility group AT-hook 1 -0.0200252
CENPE centromere protein E, 312kDa -0.0197262
MT2A metallothionein 2A -0.0197103
RPL19 ribosomal protein L19 -0.0194317
BZW2 basic leucine zipper and W2 domains 2 -0.018528
RPS25 ribosomal protein S25 -0.018338
INTS6 integrator complex subunit 6 -0.0182895
NACA nascent polypeptide-associated complex alpha subunit -0.0180265
RPLP0 ribosomal protein, large, P0 -0.0178743
LOC102724023 ES1 protein homolog, mitochondrial -0.0173761
CENPF centromere protein F, 350/400kDa -0.0173572
CACNB4 calcium channel, voltage-dependent, beta 4 subunit -0.017336
MYO5A myosin VA (heavy chain 12, myoxin) -0.0172264
RPL30 ribosomal protein L30 -0.0171906
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 -0.017188
RPL36A ribosomal protein L36a -0.017051
ANKRD36B ankyrin repeat domain 36B -0.0168661
RPS24 ribosomal protein S24 -0.0167058
TBCA tubulin folding cofactor A -0.0165351
ANKRD12 ankyrin repeat domain 12 -0.0163207
ARL4C ADP-ribosylation factor-like 4C -0.0162888
UQCRB ubiquinol-cytochrome c reductase binding protein -0.0162616
RPL17-C18ORF32 RPL17-C18orf32 readthrough -0.0160038
BCOR BCL6 corepressor -0.0156959
COX4I1 cytochrome c oxidase subunit IV isoform 1 -0.015629
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) -0.0151226
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.0149325
RPL5 ribosomal protein L5 -0.0148791
RPL32 ribosomal protein L32 -0.0146964
CALM1 calmodulin 1 (phosphorylase kinase, delta) -0.0146629
NDUFA4 NDUFA4, mitochondrial complex associated -0.0146506
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 -0.0145162
RPS23 ribosomal protein S23 -0.0143475
RPL35 ribosomal protein L35 -0.0143198
RPL21 ribosomal protein L21 -0.014134
RPL27 ribosomal protein L27 -0.0138132
RPS14 ribosomal protein S14 -0.0137063
AEBP2 AE binding protein 2 -0.0136776
HILPDA hypoxia inducible lipid droplet-associated -0.0134949
EMP3 epithelial membrane protein 3 -0.0134578
MRPS6 mitochondrial ribosomal protein S6 -0.0134576
RRM2 ribonucleotide reductase M2 -0.0131948
ARMH4 armadillo like helical domain containing 4 -0.0130602
S100A4 S100 calcium binding protein A4 -0.0128435
PRUNE2 prune homolog 2 (Drosophila) -0.0128393