| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Nevirapine perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Nevirapine_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0902223 |
| VCL | vinculin | 0.0835802 |
| RBM39 | RNA binding motif protein 39 | 0.0800104 |
| RPL3 | ribosomal protein L3 | 0.0794841 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.077953 |
| TXNRD1 | thioredoxin reductase 1 | 0.0771564 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0767547 |
| TJP1 | tight junction protein 1 | 0.0761528 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0760103 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0748111 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0747156 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0653029 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0639429 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0624946 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0615601 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0599624 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0576565 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0555722 |
| PKM | pyruvate kinase, muscle | 0.054195 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0537609 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0533593 |
| PDGFC | platelet derived growth factor C | 0.0527614 |
| RTN4 | reticulon 4 | 0.0523353 |
| TFG | TRK-fused gene | 0.0522471 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0514111 |
| NCKAP1 | NCK-associated protein 1 | 0.0499109 |
| PCBP2 | poly(rC) binding protein 2 | 0.0498948 |
| GOLGA4 | golgin A4 | 0.0498695 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0494154 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0477483 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.047589 |
| PYGB | phosphorylase, glycogen; brain | 0.0472888 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0471561 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0465557 |
| NUP58 | nucleoporin 58 | 0.0461311 |
| ZNF292 | zinc finger protein 292 | 0.0460983 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0456853 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0446713 |
| CRY1 | cryptochrome circadian clock 1 | 0.0444222 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0441684 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0436096 |
| CCNL1 | cyclin L1 | 0.0433986 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.042334 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0422252 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0421671 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0415014 |
| MSI2 | musashi RNA-binding protein 2 | 0.0412372 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0397267 |
| CDC73 | cell division cycle 73 | 0.03959 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0390649 |
| ECT2 | epithelial cell transforming 2 | 0.0390293 |
| WDR43 | WD repeat domain 43 | 0.0390038 |
| PTK2 | protein tyrosine kinase 2 | 0.0389383 |
| AHNAK | AHNAK nucleoprotein | 0.0383173 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0380182 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0379294 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0373948 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0370673 |
| EXOC6B | exocyst complex component 6B | 0.0365606 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0364161 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0359998 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0357539 |
| EGFR | epidermal growth factor receptor | 0.0356009 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0354391 |
| QKI | QKI, KH domain containing, RNA binding | 0.0352062 |
| COG5 | component of oligomeric golgi complex 5 | 0.0350994 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0348994 |
| YAP1 | Yes-associated protein 1 | 0.0346705 |
| HDLBP | high density lipoprotein binding protein | 0.0346152 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0343006 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0342151 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0340698 |
| PARD3 | par-3 family cell polarity regulator | 0.0336384 |
| UBC | ubiquitin C | 0.0336064 |
| PGK1 | phosphoglycerate kinase 1 | 0.0333278 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0332748 |
| NBAS | neuroblastoma amplified sequence | 0.0330719 |
| EZR | ezrin | 0.0330102 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.0329951 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0329529 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0328545 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0328123 |
| PIWIL1 | piwi-like RNA-mediated gene silencing 1 | 0.03266 |
| HDAC9 | histone deacetylase 9 | 0.0326118 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.032442 |
| MATR3 | matrin 3 | 0.0324174 |
| ZNF644 | zinc finger protein 644 | 0.0318699 |
| FLNB | filamin B, beta | 0.031793 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0317729 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0317352 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0312094 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0309402 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 0.0309185 |
| RHEB | Ras homolog enriched in brain | 0.0304355 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0304215 |
| CALU | calumenin | 0.0303039 |
| RHOA | ras homolog family member A | 0.0302834 |
| APP | amyloid beta (A4) precursor protein | 0.0300844 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0298992 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0298653 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.148334 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0747935 |
| RPS8 | ribosomal protein S8 | -0.0618944 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0590202 |
| PFN1 | profilin 1 | -0.0511258 |
| RPL35A | ribosomal protein L35a | -0.0507668 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0499978 |
| RPS6 | ribosomal protein S6 | -0.0479448 |
| RPLP2 | ribosomal protein, large, P2 | -0.0463962 |
| BMP10 | bone morphogenetic protein 10 | -0.0454617 |
| RPL7A | ribosomal protein L7a | -0.0444635 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0437111 |
| RPLP1 | ribosomal protein, large, P1 | -0.0424889 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0383581 |
| RPL37A | ribosomal protein L37a | -0.0379741 |
| RPL31 | ribosomal protein L31 | -0.0379371 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0341696 |
| RPL26 | ribosomal protein L26 | -0.03402 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0330594 |
| RPL36 | ribosomal protein L36 | -0.0325376 |
| RPS13 | ribosomal protein S13 | -0.0323924 |
| RPL34 | ribosomal protein L34 | -0.0319726 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0314458 |
| RPL9 | ribosomal protein L9 | -0.0312186 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0310772 |
| TMSB10 | thymosin beta 10 | -0.0303379 |
| RPS19 | ribosomal protein S19 | -0.0296495 |
| RACK1 | receptor for activated C kinase 1 | -0.0291081 |
| FTL | ferritin, light polypeptide | -0.0285201 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0282125 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0273367 |
| RPS21 | ribosomal protein S21 | -0.0265296 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0264502 |
| ACTG1 | actin gamma 1 | -0.0263954 |
| DIAPH3 | diaphanous-related formin 3 | -0.0262904 |
| RPS3 | ribosomal protein S3 | -0.0252323 |
| RPS27A | ribosomal protein S27a | -0.0248653 |
| RPS12 | ribosomal protein S12 | -0.0247984 |
| S100A9 | S100 calcium binding protein A9 | -0.0243863 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.02386 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0234669 |
| RPS27 | ribosomal protein S27 | -0.0232882 |
| HJURP | Holliday junction recognition protein | -0.023258 |
| RPL18 | ribosomal protein L18 | -0.0229127 |
| NAV2 | neuron navigator 2 | -0.0226138 |
| RPL23 | ribosomal protein L23 | -0.0225052 |
| RPL28 | ribosomal protein L28 | -0.0223211 |
| RPS17 | ribosomal protein S17 | -0.0217766 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0216299 |
| RPS16 | ribosomal protein S16 | -0.0210867 |
| RPL12 | ribosomal protein L12 | -0.0209977 |
| RPS29 | ribosomal protein S29 | -0.0209491 |
| MKI67 | marker of proliferation Ki-67 | -0.0208812 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0208546 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.0204726 |
| HMGA1 | high mobility group AT-hook 1 | -0.0200252 |
| CENPE | centromere protein E, 312kDa | -0.0197262 |
| MT2A | metallothionein 2A | -0.0197103 |
| RPL19 | ribosomal protein L19 | -0.0194317 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.018528 |
| RPS25 | ribosomal protein S25 | -0.018338 |
| INTS6 | integrator complex subunit 6 | -0.0182895 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0180265 |
| RPLP0 | ribosomal protein, large, P0 | -0.0178743 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0173761 |
| CENPF | centromere protein F, 350/400kDa | -0.0173572 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.017336 |
| MYO5A | myosin VA (heavy chain 12, myoxin) | -0.0172264 |
| RPL30 | ribosomal protein L30 | -0.0171906 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | -0.017188 |
| RPL36A | ribosomal protein L36a | -0.017051 |
| ANKRD36B | ankyrin repeat domain 36B | -0.0168661 |
| RPS24 | ribosomal protein S24 | -0.0167058 |
| TBCA | tubulin folding cofactor A | -0.0165351 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0163207 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0162888 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0162616 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0160038 |
| BCOR | BCL6 corepressor | -0.0156959 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.015629 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -0.0151226 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0149325 |
| RPL5 | ribosomal protein L5 | -0.0148791 |
| RPL32 | ribosomal protein L32 | -0.0146964 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0146629 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0146506 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0145162 |
| RPS23 | ribosomal protein S23 | -0.0143475 |
| RPL35 | ribosomal protein L35 | -0.0143198 |
| RPL21 | ribosomal protein L21 | -0.014134 |
| RPL27 | ribosomal protein L27 | -0.0138132 |
| RPS14 | ribosomal protein S14 | -0.0137063 |
| AEBP2 | AE binding protein 2 | -0.0136776 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0134949 |
| EMP3 | epithelial membrane protein 3 | -0.0134578 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0134576 |
| RRM2 | ribonucleotide reductase M2 | -0.0131948 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0130602 |
| S100A4 | S100 calcium binding protein A4 | -0.0128435 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.0128393 |