Nickel Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description Chemical element (nickel group element atom) with atomic number 28. (Chemical Entities of Biological Interest Ontology, CHEBI_28112)
External Link http://ctdbase.org/detail.go?type=chem&acc=D009532
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Genes

72 genes/proteins interacting with the chemical Nickel from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACO1 aconitase 1, soluble
AKT1 v-akt murine thymoma viral oncogene homolog 1
APP amyloid beta (A4) precursor protein
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BIRC5 baculoviral IAP repeat containing 5
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CAT catalase
CCL2 chemokine (C-C motif) ligand 2
CD80 CD80 molecule
CD86 CD86 molecule
CDC20 cell division cycle 20
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL2 chemokine (C-X-C motif) ligand 2
EHMT2 euchromatic histone-lysine N-methyltransferase 2
EPAS1 endothelial PAS domain protein 1
F2 coagulation factor II (thrombin)
GSR glutathione reductase
HDAC8 histone deacetylase 8
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST2H2AC histone cluster 2, H2ac
HIST3H2BB histone cluster 3, H2bb
HIST3H3 histone cluster 3, H3
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HMOX1 heme oxygenase 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
ICAM1 intercellular adhesion molecule 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IL1B interleukin 1, beta
IL5 interleukin 5
IL6 interleukin 6
INSR insulin receptor
IRS4 insulin receptor substrate 4
KDM3A lysine (K)-specific demethylase 3A
KEAP1 kelch-like ECH-associated protein 1
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MDM4 MDM4, p53 regulator
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MT2A metallothionein 2A
MTF1 metal-regulatory transcription factor 1
NDRG1 N-myc downstream regulated 1
NGF nerve growth factor (beta polypeptide)
NOS3 nitric oxide synthase 3 (endothelial cell)
PDGFB platelet-derived growth factor beta polypeptide
PRNP prion protein
SCO1 SCO1 cytochrome c oxidase assembly protein
SFTPB surfactant protein B
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SP1 Sp1 transcription factor
SPRY2 sprouty homolog 2 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT1 signal transducer and activator of transcription 1, 91kDa
TNF tumor necrosis factor
TP53 tumor protein p53
UBE2A ubiquitin-conjugating enzyme E2A
UBE2E1 ubiquitin-conjugating enzyme E2E 1
VEGFA vascular endothelial growth factor A