| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Niclosamide (olamine) perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Niclosamide (olamine)_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0828567 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0729617 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0714124 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0642893 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0608052 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0579796 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0532394 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0513339 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0498284 |
| GOLGA4 | golgin A4 | 0.0472734 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0448299 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.044523 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0407209 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0404347 |
| FNDC3B | fibronectin type III domain containing 3B | 0.039087 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0383006 |
| SBF2 | SET binding factor 2 | 0.0382179 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0372684 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0366468 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0365111 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0356342 |
| CADM1 | cell adhesion molecule 1 | 0.0351795 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0344322 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.0341474 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0341195 |
| RTN4 | reticulon 4 | 0.0334642 |
| ATP13A3 | ATPase type 13A3 | 0.0328166 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0320173 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0318618 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0317709 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0315956 |
| NDRG1 | N-myc downstream regulated 1 | 0.0308285 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.0305931 |
| SEPTIN9 | septin 9 | 0.0296637 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0291542 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0289301 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0289055 |
| CALU | calumenin | 0.0288816 |
| PTMA | prothymosin, alpha | 0.0287752 |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.0286954 |
| RNF220 | ring finger protein 220 | 0.0285501 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0280046 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0278456 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0277995 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0276772 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0276593 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0274722 |
| COG5 | component of oligomeric golgi complex 5 | 0.0274503 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0272009 |
| TPM3 | tropomyosin 3 | 0.0271723 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0271477 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0270616 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0269277 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0269148 |
| SP3 | Sp3 transcription factor | 0.0268879 |
| MSN | moesin | 0.0266793 |
| MAP1B | microtubule-associated protein 1B | 0.0255651 |
| ARRDC3 | arrestin domain containing 3 | 0.0255631 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0251376 |
| TFG | TRK-fused gene | 0.0243198 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0239425 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0239301 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.023883 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0237176 |
| CENPF | centromere protein F, 350/400kDa | 0.0230781 |
| PLEC | plectin | 0.0229684 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0229116 |
| XPO1 | exportin 1 | 0.0228291 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.022653 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0226345 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0225934 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0224765 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0224738 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0223078 |
| OPTN | optineurin | 0.0222511 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.022234 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0221669 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0219966 |
| OGA | O-GlcNAcase | 0.0219039 |
| JMJD1C | jumonji domain containing 1C | 0.0218351 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0217606 |
| GOLGA2 | golgin A2 | 0.0215885 |
| AFTPH | aftiphilin | 0.0215522 |
| JAK1 | Janus kinase 1 | 0.0213478 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | 0.0211037 |
| DSTN | destrin (actin depolymerizing factor) | 0.0210858 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0209456 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0208059 |
| RLIM | ring finger protein, LIM domain interacting | 0.0207389 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0206609 |
| LRRC49 | leucine rich repeat containing 49 | 0.0206103 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.020519 |
| RUNX1 | runt-related transcription factor 1 | 0.0204868 |
| ADAR | adenosine deaminase, RNA-specific | 0.0204155 |
| ITGAV | integrin, alpha V | 0.0203605 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0203485 |
| NRP2 | neuropilin 2 | 0.0203392 |
| YME1L1 | YME1-like 1 ATPase | 0.0203337 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0200278 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0198846 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.109359 |
| FRMD4A | FERM domain containing 4A | -0.0924902 |
| GPC6 | glypican 6 | -0.0813936 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0561129 |
| TMSB10 | thymosin beta 10 | -0.0531891 |
| GLIS3 | GLIS family zinc finger 3 | -0.0462769 |
| CP | ceruloplasmin (ferroxidase) | -0.0422941 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0403567 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0289636 |
| ASPH | aspartate beta-hydroxylase | -0.0287564 |
| INTS6 | integrator complex subunit 6 | -0.0273765 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0270025 |
| RIGI | RNA sensor RIG-I | -0.0269437 |
| EHBP1 | EH domain binding protein 1 | -0.0269219 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0248661 |
| IFI44L | interferon-induced protein 44-like | -0.0228898 |
| KYNU | kynureninase | -0.0220745 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | -0.0216422 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0216049 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0210692 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0191312 |
| EFNA5 | ephrin-A5 | -0.0184378 |
| PRKCA | protein kinase C, alpha | -0.0169105 |
| FAM20C | family with sequence similarity 20, member C | -0.0157821 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0154033 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0149923 |
| UBAP2 | ubiquitin associated protein 2 | -0.0148967 |
| DIAPH3 | diaphanous-related formin 3 | -0.0148487 |
| EXOC4 | exocyst complex component 4 | -0.0146695 |
| HLA-B | major histocompatibility complex, class I, B | -0.0145517 |
| PTH2R | parathyroid hormone 2 receptor | -0.0142614 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0141744 |
| APOL1 | apolipoprotein L, 1 | -0.0141618 |
| PALLD | palladin, cytoskeletal associated protein | -0.0139296 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0136113 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.013581 |
| ACTG1 | actin gamma 1 | -0.0135408 |
| SORCS2 | sortilin-related VPS10 domain containing receptor 2 | -0.0132915 |
| RBPMS | RNA binding protein with multiple splicing | -0.0129278 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0128901 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0128409 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 | -0.012805 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0124506 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0123542 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0122927 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0122885 |
| BNC2 | basonuclin 2 | -0.0120449 |
| COL27A1 | collagen, type XXVII, alpha 1 | -0.0120399 |
| RPL31 | ribosomal protein L31 | -0.0117944 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0114941 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0114209 |
| DGKI | diacylglycerol kinase, iota | -0.0114015 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.011349 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0112421 |
| VCL | vinculin | -0.0112205 |
| RRM2 | ribonucleotide reductase M2 | -0.011195 |
| TENM3 | teneurin transmembrane protein 3 | -0.0111161 |
| ANXA4 | annexin A4 | -0.0110894 |
| RPL28 | ribosomal protein L28 | -0.011018 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 | -0.0108492 |
| B2M | beta-2-microglobulin | -0.0106568 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0105853 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0104871 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0104722 |
| TBCA | tubulin folding cofactor A | -0.0104003 |
| OXR1 | oxidation resistance 1 | -0.010269 |
| PLSCR2 | phospholipid scramblase 2 | -0.0101656 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0100072 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0100071 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00993248 |
| POTEF | POTE ankyrin domain family, member F | -0.00992769 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0098841 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.00978675 |
| ADIPOR2 | adiponectin receptor 2 | -0.00970453 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.00965891 |
| CUX1 | cut-like homeobox 1 | -0.00958725 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.00955156 |
| RPL23 | ribosomal protein L23 | -0.00954417 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.00948256 |
| GEN1 | GEN1 Holliday junction 5' flap endonuclease | -0.00946444 |
| NEK10 | NIMA-related kinase 10 | -0.00945452 |
| EGFR | epidermal growth factor receptor | -0.00942883 |
| TPM1 | tropomyosin 1 (alpha) | -0.00933618 |
| C5AR1 | complement component 5a receptor 1 | -0.00928632 |
| CDR2 | cerebellar degeneration-related protein 2, 62kDa | -0.00928165 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.00924198 |
| RDH10 | retinol dehydrogenase 10 (all-trans) | -0.00921134 |
| SP100 | SP100 nuclear antigen | -0.00918928 |
| PILRA | paired immunoglobin-like type 2 receptor alpha | -0.00917545 |
| CLMP | CXADR-like membrane protein | -0.00909907 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.00908365 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.00907935 |
| BICC1 | BicC family RNA binding protein 1 | -0.0090636 |
| CDK14 | cyclin-dependent kinase 14 | -0.00905709 |
| MT2A | metallothionein 2A | -0.00898851 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa | -0.00898605 |
| FUS | FUS RNA binding protein | -0.00884474 |
| NCOA2 | nuclear receptor coactivator 2 | -0.00884005 |
| KALRN | kalirin, RhoGEF kinase | -0.00883306 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.00882412 |
