| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Niclosamide (olamine) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Niclosamide (olamine)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.0899248 |
| VEGFA | vascular endothelial growth factor A | 0.0844591 |
| ZNF292 | zinc finger protein 292 | 0.0757237 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.058971 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0562048 |
| GOLGA4 | golgin A4 | 0.0534217 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0529108 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0513104 |
| QKI | QKI, KH domain containing, RNA binding | 0.0512971 |
| JMJD1C | jumonji domain containing 1C | 0.0498859 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0495218 |
| RPL13A | ribosomal protein L13a | 0.0493518 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0469638 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0460676 |
| PDGFC | platelet derived growth factor C | 0.0423021 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0417218 |
| FAM168A | family with sequence similarity 168, member A | 0.0403896 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.040306 |
| RPL11 | ribosomal protein L11 | 0.0392128 |
| RPS6 | ribosomal protein S6 | 0.0390131 |
| RPS2 | ribosomal protein S2 | 0.0361492 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0356386 |
| USP3 | ubiquitin specific peptidase 3 | 0.0355581 |
| RNF145 | ring finger protein 145 | 0.0354092 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0351321 |
| PHF3 | PHD finger protein 3 | 0.0350282 |
| KIAA1958 | KIAA1958 | 0.0348646 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0343556 |
| RLF | rearranged L-myc fusion | 0.0339728 |
| MGP | matrix Gla protein | 0.0339509 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0337958 |
| RYBP | RING1 and YY1 binding protein | 0.0337438 |
| CREBRF | CREB3 regulatory factor | 0.0332422 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0327624 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.031855 |
| HELZ | helicase with zinc finger | 0.0313017 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0310801 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0308358 |
| ADM | adrenomedullin | 0.0297349 |
| SBF2 | SET binding factor 2 | 0.0293508 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0287532 |
| RPL35A | ribosomal protein L35a | 0.0280625 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0280179 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0278281 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.027353 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0271928 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0271334 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0268532 |
| TMF1 | TATA element modulatory factor 1 | 0.0268467 |
| DIPK2A | divergent protein kinase domain 2A | 0.026473 |
| SFTPA2 | surfactant protein A2 | 0.0259933 |
| CD70 | CD70 molecule | 0.0259708 |
| EPC1 | enhancer of polycomb homolog 1 (Drosophila) | 0.0258499 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0255814 |
| RBM27 | RNA binding motif protein 27 | 0.0250679 |
| CALR | calreticulin | 0.0248641 |
| DMXL1 | Dmx-like 1 | 0.0247675 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0245502 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0245358 |
| TPD52 | tumor protein D52 | 0.0244409 |
| RPL21 | ribosomal protein L21 | 0.0244088 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0243707 |
| MT2A | metallothionein 2A | 0.0241394 |
| RFX7 | regulatory factor X, 7 | 0.0235742 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0235448 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0233514 |
| MEOX2 | mesenchyme homeobox 2 | 0.0232909 |
| SRP54 | signal recognition particle 54kDa | 0.0231678 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0230302 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.022915 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.0229031 |
| OGA | O-GlcNAcase | 0.0227691 |
| RPS25 | ribosomal protein S25 | 0.0227425 |
| RPL12 | ribosomal protein L12 | 0.0226289 |
| MTF2 | metal response element binding transcription factor 2 | 0.0224844 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0222996 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0222017 |
| ZNF451 | zinc finger protein 451 | 0.0219955 |
| SMAP1 | small ArfGAP 1 | 0.021993 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0217852 |
| RANBP9 | RAN binding protein 9 | 0.0216314 |
| RREB1 | ras responsive element binding protein 1 | 0.02161 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | 0.0215828 |
| CHKA | choline kinase alpha | 0.0214932 |
| USP47 | ubiquitin specific peptidase 47 | 0.0213824 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0213553 |
| MED13L | mediator complex subunit 13-like | 0.0213021 |
| ZNF608 | zinc finger protein 608 | 0.0211394 |
| SYF2 | SYF2 pre-mRNA-splicing factor | 0.021097 |
| RPS12 | ribosomal protein S12 | 0.021073 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0210605 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0210033 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0209614 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0209572 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0209279 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0208923 |
| FBXO11 | F-box protein 11 | 0.0208751 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0208208 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0207884 |
| FMNL2 | formin-like 2 | 0.0207839 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.191274 |
| VIM | vimentin | -0.124839 |
| HMGA2 | high mobility group AT-hook 2 | -0.112727 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.111492 |
| CADM2 | cell adhesion molecule 2 | -0.107492 |
| PEG10 | paternally expressed 10 | -0.101857 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0930531 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0870161 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0829906 |
| MEST | mesoderm specific transcript | -0.0792272 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0735542 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.066908 |
| ENO1 | enolase 1, (alpha) | -0.0663444 |
| UBC | ubiquitin C | -0.0652651 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0649267 |
| SEPTIN11 | septin 11 | -0.0646344 |
| RPS27A | ribosomal protein S27a | -0.0572344 |
| RANBP17 | RAN binding protein 17 | -0.0531169 |
| CDK6 | cyclin-dependent kinase 6 | -0.0519339 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0513475 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0490921 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0479116 |
| PCBP2 | poly(rC) binding protein 2 | -0.0471344 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0457183 |
| BCOR | BCL6 corepressor | -0.0455873 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0448362 |
| AHNAK | AHNAK nucleoprotein | -0.0440242 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0438136 |
| CANX | calnexin | -0.0433404 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0431361 |
| FRYL | FRY-like | -0.0428367 |
| EXOC4 | exocyst complex component 4 | -0.0424039 |
| MKI67 | marker of proliferation Ki-67 | -0.0408338 |
| DIAPH3 | diaphanous-related formin 3 | -0.0404516 |
| APP | amyloid beta (A4) precursor protein | -0.0399587 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0392156 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0384062 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0383418 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0367157 |
| CENPF | centromere protein F, 350/400kDa | -0.0362935 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0360891 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0360177 |
| LDHA | lactate dehydrogenase A | -0.0356462 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | -0.0350781 |
| ENAH | enabled homolog (Drosophila) | -0.0348394 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0342853 |
| NBEA | neurobeachin | -0.0342303 |
| SPAG9 | sperm associated antigen 9 | -0.033785 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0337194 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0333564 |
| GSE1 | Gse1 coiled-coil protein | -0.0332197 |
| CUX1 | cut-like homeobox 1 | -0.0329951 |
| EXOC6B | exocyst complex component 6B | -0.0326812 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0326787 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0324013 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0320264 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0319619 |
| WWOX | WW domain containing oxidoreductase | -0.0316895 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0316427 |
| TPM4 | tropomyosin 4 | -0.0307957 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | -0.0307565 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0304095 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0302973 |
| BPTF | bromodomain PHD finger transcription factor | -0.0302451 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0301483 |
| RPL23 | ribosomal protein L23 | -0.029955 |
| TCF12 | transcription factor 12 | -0.0293357 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | -0.029223 |
| HMGB2 | high mobility group box 2 | -0.0291403 |
| FNIP1 | folliculin interacting protein 1 | -0.0290827 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0289381 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0288778 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0288447 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0287029 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0285265 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.0284963 |
| HDAC8 | histone deacetylase 8 | -0.0282313 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | -0.0281988 |
| IER3 | immediate early response 3 | -0.0281229 |
| UVRAG | UV radiation resistance associated | -0.027974 |
| FOXP1 | forkhead box P1 | -0.0277174 |
| CENPE | centromere protein E, 312kDa | -0.0273233 |
| PRELID2 | PRELI domain containing 2 | -0.0270647 |
| SMC1A | structural maintenance of chromosomes 1A | -0.0266525 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0264625 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0263673 |
| TNPO1 | transportin 1 | -0.0263421 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0262724 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | -0.0262026 |
| TXNRD1 | thioredoxin reductase 1 | -0.0260037 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0259714 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0258841 |
| CCNB1 | cyclin B1 | -0.025568 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0255678 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0254545 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0253292 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0253255 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0252998 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0251617 |
| MATR3 | matrin 3 | -0.0251475 |
