| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Niclosamide (olamine) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Niclosamide (olamine)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.175779 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0954957 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0824915 |
| PLEC | plectin | 0.0795693 |
| AHNAK | AHNAK nucleoprotein | 0.070312 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0663521 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0658788 |
| ITGA6 | integrin, alpha 6 | 0.0656628 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0649982 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0626093 |
| NDRG1 | N-myc downstream regulated 1 | 0.0602043 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0575065 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0555004 |
| FAM107B | family with sequence similarity 107, member B | 0.0554832 |
| OGA | O-GlcNAcase | 0.0551404 |
| SDC4 | syndecan 4 | 0.0484461 |
| CAPRIN2 | caprin family member 2 | 0.0475797 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0461175 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0459544 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.042955 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0418052 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0417288 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0406822 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0398767 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0396178 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.039607 |
| PGK1 | phosphoglycerate kinase 1 | 0.0368039 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0364163 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0354803 |
| LDHA | lactate dehydrogenase A | 0.0345839 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0338808 |
| DSG2 | desmoglein 2 | 0.0338508 |
| PTMA | prothymosin, alpha | 0.0326882 |
| ZNF292 | zinc finger protein 292 | 0.0323847 |
| ANXA2 | annexin A2 | 0.0319437 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0317829 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.0314765 |
| ANLN | anillin, actin binding protein | 0.0301757 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.028771 |
| S100A10 | S100 calcium binding protein A10 | 0.0281763 |
| EFNA5 | ephrin-A5 | 0.0281014 |
| VCL | vinculin | 0.0276353 |
| NPAS2 | neuronal PAS domain protein 2 | 0.026578 |
| FAM13A | family with sequence similarity 13, member A | 0.0263229 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0257322 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0255033 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.024857 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0245122 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0243441 |
| ITGB4 | integrin, beta 4 | 0.0243345 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0233382 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.022719 |
| FSCN1 | fascin actin-bundling protein 1 | 0.0226614 |
| HPCAL1 | hippocalcin-like 1 | 0.0223458 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0222913 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0219865 |
| TPD52 | tumor protein D52 | 0.0213809 |
| EMP1 | epithelial membrane protein 1 | 0.0212869 |
| CTBP2 | C-terminal binding protein 2 | 0.0208788 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0208688 |
| SMAD3 | SMAD family member 3 | 0.0208622 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0205046 |
| CSTB | cystatin B (stefin B) | 0.020247 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0201971 |
| NEK7 | NIMA-related kinase 7 | 0.0198971 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0196886 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0194948 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0193867 |
| SERTAD2 | SERTA domain containing 2 | 0.0191949 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0190954 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0189713 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0187417 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0187146 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.018713 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0184932 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0184923 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0184357 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0183809 |
| KRT8 | keratin 8, type II | 0.0183668 |
| AFDN | afadin, adherens junction formation factor | 0.0183436 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0181715 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0180492 |
| TUFT1 | tuftelin 1 | 0.0177932 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0177093 |
| NPTN | neuroplastin | 0.0176381 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.01722 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0170915 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0170395 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0169082 |
| PTK2B | protein tyrosine kinase 2 beta | 0.0165571 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0162887 |
| FOXO3 | forkhead box O3 | 0.016247 |
| SBF2 | SET binding factor 2 | 0.0161928 |
| S100A6 | S100 calcium binding protein A6 | 0.0160934 |
| ANO6 | anoctamin 6 | 0.0160656 |
| MCU | mitochondrial calcium uniporter | 0.015894 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0155596 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.015407 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0152811 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0152381 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | -0.203042 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.11294 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.112052 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0998448 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0970073 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.095487 |
| TMSB10 | thymosin beta 10 | -0.0876392 |
| LAMB3 | laminin, beta 3 | -0.0731254 |
| TXNIP | thioredoxin interacting protein | -0.0713406 |
| EGFR | epidermal growth factor receptor | -0.0673112 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.063914 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0602106 |
| KLK10 | kallikrein-related peptidase 10 | -0.059381 |
| FTL | ferritin, light polypeptide | -0.0570329 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0557808 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0529434 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0525206 |
| B2M | beta-2-microglobulin | -0.0483304 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0481104 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0471582 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0443202 |
| PARD3 | par-3 family cell polarity regulator | -0.0433089 |
| CLMP | CXADR-like membrane protein | -0.0422928 |
| TPM4 | tropomyosin 4 | -0.0415033 |
| HMGA1 | high mobility group AT-hook 1 | -0.0413609 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0413479 |
| EGR1 | early growth response 1 | -0.0402638 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0398084 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0372664 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0360502 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0355704 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0349501 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0345277 |
| AK1 | adenylate kinase 1 | -0.0345036 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0342742 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0342482 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0339725 |
| FOSL1 | FOS-like antigen 1 | -0.0332248 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.032727 |
| MXD1 | MAX dimerization protein 1 | -0.0324349 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0323389 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0317061 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.0313084 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0312772 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.031164 |
| DIAPH1 | diaphanous-related formin 1 | -0.0305049 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0304446 |
| RPL35A | ribosomal protein L35a | -0.0298046 |
| VCAN | versican | -0.0287167 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0285268 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0283022 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0280144 |
| RPS21 | ribosomal protein S21 | -0.0276117 |
| MIDN | midnolin | -0.0275187 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0274808 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0274737 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0273515 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0271644 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0271366 |
| ARF4 | ADP-ribosylation factor 4 | -0.0269278 |
| GOLGB1 | golgin B1 | -0.0267957 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0266444 |
| RPLP2 | ribosomal protein, large, P2 | -0.0265692 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0263884 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0263554 |
| FERMT1 | fermitin family member 1 | -0.0263372 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.026306 |
| RPL23 | ribosomal protein L23 | -0.026277 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0262247 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0260604 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0259416 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.025818 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0255253 |
| UPP1 | uridine phosphorylase 1 | -0.02541 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0253408 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0251257 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0248826 |
| HDAC9 | histone deacetylase 9 | -0.0234643 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0233906 |
| SVIL | supervillin | -0.0231239 |
| USP34 | ubiquitin specific peptidase 34 | -0.0230102 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0228872 |
| THBD | thrombomodulin | -0.0228683 |
| UBAP2 | ubiquitin associated protein 2 | -0.0227898 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0227662 |
| IER3 | immediate early response 3 | -0.0226888 |
| RPL31 | ribosomal protein L31 | -0.022636 |
| FAM3C | family with sequence similarity 3, member C | -0.022634 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0224668 |
| PCBP2 | poly(rC) binding protein 2 | -0.0212925 |
| DIAPH2 | diaphanous-related formin 2 | -0.0212608 |
| LMO7 | LIM domain 7 | -0.021153 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0209843 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0206182 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0204079 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0202998 |
| RPS13 | ribosomal protein S13 | -0.0200427 |
| RNF213 | ring finger protein 213 | -0.0198094 |
| RPS27 | ribosomal protein S27 | -0.0196154 |
| AREG | amphiregulin | -0.0194634 |
