| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Niclosamide (olamine) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Niclosamide (olamine)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.101996 |
| NCOA3 | nuclear receptor coactivator 3 | 0.101211 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0782461 |
| PTMA | prothymosin, alpha | 0.0700859 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0424243 |
| RPL23 | ribosomal protein L23 | 0.0412572 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0407342 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0356359 |
| TMEM123 | transmembrane protein 123 | 0.0337561 |
| DSTN | destrin (actin depolymerizing factor) | 0.0315107 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0295228 |
| ZNF292 | zinc finger protein 292 | 0.0283883 |
| VEGFA | vascular endothelial growth factor A | 0.027641 |
| TPD52 | tumor protein D52 | 0.0272957 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0269582 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0256604 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0254876 |
| ACTG1 | actin gamma 1 | 0.0250636 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0244551 |
| RPL35A | ribosomal protein L35a | 0.024262 |
| MSI2 | musashi RNA-binding protein 2 | 0.0238442 |
| RPL37A | ribosomal protein L37a | 0.0237234 |
| USP3 | ubiquitin specific peptidase 3 | 0.0231146 |
| RBM25 | RNA binding motif protein 25 | 0.0229062 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0219329 |
| SET | SET nuclear proto-oncogene | 0.0218097 |
| POLD3 | polymerase (DNA-directed), delta 3, accessory subunit | 0.0217726 |
| FNBP1L | formin binding protein 1-like | 0.0212466 |
| PNN | pinin, desmosome associated protein | 0.0211204 |
| CCNY | cyclin Y | 0.0209576 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0206765 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0205581 |
| PLEKHA7 | pleckstrin homology domain containing, family A member 7 | 0.0204796 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0199409 |
| MCL1 | myeloid cell leukemia 1 | 0.0198563 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0196528 |
| TCEA2 | transcription elongation factor A (SII), 2 | 0.0193397 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0191174 |
| JMJD1C | jumonji domain containing 1C | 0.018988 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0188254 |
| ICAM1 | intercellular adhesion molecule 1 | 0.018731 |
| RNF24 | ring finger protein 24 | 0.0184625 |
| CDYL | chromodomain protein, Y-like | 0.0178563 |
| VIPR2 | vasoactive intestinal peptide receptor 2 | 0.0177999 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0176593 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0176327 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0175681 |
| RIOK3 | RIO kinase 3 | 0.0175233 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0172315 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0172294 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0171522 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0170214 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0169712 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0169008 |
| RTN3 | reticulon 3 | 0.0168445 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0168289 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0167206 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0167139 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0165771 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0163991 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0162866 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0162279 |
| GRHL1 | grainyhead-like 1 (Drosophila) | 0.0161553 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0160991 |
| NEK6 | NIMA-related kinase 6 | 0.0160824 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0160582 |
| NDUFAF6 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 | 0.0160416 |
| RPS6 | ribosomal protein S6 | 0.0159069 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0158828 |
| TNRC6A | trinucleotide repeat containing 6A | 0.015876 |
| MED24 | mediator complex subunit 24 | 0.0155844 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0155545 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0155095 |
| NAA25 | N(alpha)-acetyltransferase 25, NatB auxiliary subunit | 0.0153768 |
| RPL37 | ribosomal protein L37 | 0.0153163 |
| TUFT1 | tuftelin 1 | 0.0151533 |
| UVRAG | UV radiation resistance associated | 0.0150456 |
| WDR45B | WD repeat domain 45B | 0.0150165 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0148705 |
| RREB1 | ras responsive element binding protein 1 | 0.0148288 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.014709 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | 0.0146659 |
| TMSB4X | thymosin beta 4, X-linked | 0.0146658 |
| RYBP | RING1 and YY1 binding protein | 0.0145771 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0145324 |
| GPD2 | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) | 0.0144817 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0143584 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.014315 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.014312 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0142344 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0142127 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0141772 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0141759 |
| OGA | O-GlcNAcase | 0.0141443 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0140317 |
| RLF | rearranged L-myc fusion | 0.0139517 |
| CALR | calreticulin | 0.013768 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0135829 |
| RNF149 | ring finger protein 149 | 0.0133226 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0132307 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.161414 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.111412 |
| ASPH | aspartate beta-hydroxylase | -0.105715 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0916069 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.088439 |
| CDK12 | cyclin-dependent kinase 12 | -0.0772641 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0747227 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.0740389 |
| VMP1 | vacuole membrane protein 1 | -0.0736806 |
| LASP1 | LIM and SH3 protein 1 | -0.0666159 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.066249 |
| EXT1 | exostosin glycosyltransferase 1 | -0.063907 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0635951 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0606524 |
| OSMR | oncostatin M receptor | -0.0586506 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.058146 |
| ANKRD36C | ankyrin repeat domain 36C | -0.0555689 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0546443 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0537685 |
| SMYD3 | SET and MYND domain containing 3 | -0.0535034 |
| SRCIN1 | SRC kinase signaling inhibitor 1 | -0.0520708 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0498876 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0494572 |
| CLTC | clathrin, heavy chain (Hc) | -0.0462128 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0428954 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0423814 |
| NTN4 | netrin 4 | -0.0408815 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0406276 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0405826 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0405318 |
| GSE1 | Gse1 coiled-coil protein | -0.0400487 |
| TENM2 | teneurin transmembrane protein 2 | -0.0399529 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0389414 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0378087 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0377974 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0376189 |
| S100A9 | S100 calcium binding protein A9 | -0.0373921 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0370677 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0365208 |
| ENAH | enabled homolog (Drosophila) | -0.0362468 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0360588 |
| TC2N | tandem C2 domains, nuclear | -0.0359882 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0358687 |
| DUSP16 | dual specificity phosphatase 16 | -0.0356504 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0354674 |
| NF1 | neurofibromin 1 | -0.0352064 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0351399 |
| S100A8 | S100 calcium binding protein A8 | -0.0348671 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0347288 |
| DSPP | dentin sialophosphoprotein | -0.0345027 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0338772 |
| BCAS1 | breast carcinoma amplified sequence 1 | -0.0338573 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0335259 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0334358 |
| TMC5 | transmembrane channel-like 5 | -0.0331405 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0325207 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0324444 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0321344 |
| MT2A | metallothionein 2A | -0.0319158 |
| CCND1 | cyclin D1 | -0.0318619 |
| PTK2 | protein tyrosine kinase 2 | -0.0316562 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.031412 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0312148 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0309235 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0308337 |
| MED13L | mediator complex subunit 13-like | -0.0304281 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0303104 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0302093 |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) | -0.0301927 |
| TXNRD1 | thioredoxin reductase 1 | -0.029627 |
| VAV3 | vav 3 guanine nucleotide exchange factor | -0.029393 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | -0.0292422 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0290179 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0289836 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0287134 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0286473 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.0283817 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 | -0.0282279 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0279705 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0279343 |
| CD164 | CD164 molecule, sialomucin | -0.0278715 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0278332 |
| KLF6 | Kruppel-like factor 6 | -0.0277464 |
| TTC6 | tetratricopeptide repeat domain 6 | -0.0276305 |
| BPTF | bromodomain PHD finger transcription factor | -0.0273465 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0270548 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0268187 |
| MYOF | myoferlin | -0.0267028 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.0264302 |
| TMEM45B | transmembrane protein 45B | -0.0264193 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0259901 |
| PLK2 | polo-like kinase 2 | -0.0257324 |
| SEPTIN9 | septin 9 | -0.0254663 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.025434 |
| FADS2 | fatty acid desaturase 2 | -0.0252079 |
| PRLR | prolactin receptor | -0.0250753 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0250731 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0250352 |
| NCOA6 | nuclear receptor coactivator 6 | -0.0249405 |
| AHR | aryl hydrocarbon receptor | -0.0247406 |
